NB10064329V
ILT5/CD85a/LILRB3 Antibody (4F9), DyLight 405, Novus Biologicals™
Manufacturer: Novus Biologicals
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | NB10064329V-Each-of-1 | In Stock | ₹ 53,218.32 |
NB10064329V - Each of 1
In Stock
Quantity
1
Base Price: ₹ 53,218.32
GST (18%): ₹ 9,579.298
Total Price: ₹ 62,797.618
Antigen
ILT5/CD85a/LILRB3
Classification
Monoclonal
Conjugate
DyLight 405
Formulation
50mM Sodium Borate with 0.05% Sodium Azide
Gene Symbols
LILRB3
Immunogen
Monocyte derived dendritic cells
Quantity
0.1 mL
Primary or Secondary
Primary
Test Specificity
NB100-64329 is specific for human CD85a (leucocyte immunoglobulin-like receptor, subfamily B, member 3/ LILRB3), also known as ILT-5, expressed by monocytes, dendritic cells, macrophages, subpopulation of T lymphocytes, B cells and at high levels on plasma cells. CD85a is a 631 amino acid type I transmembrane glycoprotein, which contains four immunoreceptor tyrosine-based inhibition motif (ITIM) sequences within a long cytoplasmic tail. Phosphorylation of the tyrosine residues within ITIMs is known to enable the binding and activation of protein tyrosine phosphatases, which act as cell signalling modulators and inhibitors of cell activation.
Content And Storage
Store at 4C in the dark.
Isotype
IgG1
Applications
Flow Cytometry, Immunohistochemistry, Immunohistochemistry (Frozen)
Clone
4F9
Dilution
Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Frozen
Gene Alias
CD85 antigen-like family member A, CD85a antigen, HL9Immunoglobulin-like transcript 5, ILT-5, ILT5CD85a, Leukocyte immunoglobulin-like receptor 3, leukocyte immunoglobulin-like receptor subfamily B member 3, leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), LIR3CD85A, LIR-3MGC138403, member 3, Monocyte inhibitory receptor HL9, PIRB
Host Species
Mouse
Purification Method
Protein G purified
Regulatory Status
RUO
Gene ID (Entrez)
11025
Target Species
Human
Form
Purified
Related Products
Description
- ILT5/CD85a/LILRB3 Monoclonal specifically detects ILT5/CD85a/LILRB3 in Human samples
- It is validated for Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Frozen.
Compare Similar Items
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Antigen: ILT5/CD85a/LILRB3
Classification: Monoclonal
Conjugate: DyLight 405
Formulation: 50mM Sodium Borate with 0.05% Sodium Azide
Gene Symbols: LILRB3
Immunogen: Monocyte derived dendritic cells
Quantity: 0.1 mL
Primary or Secondary: Primary
Test Specificity: NB100-64329 is specific for human CD85a (leucocyte immunoglobulin-like receptor, subfamily B, member 3/ LILRB3), also known as ILT-5, expressed by monocytes, dendritic cells, macrophages, subpopulation of T lymphocytes, B cells and at high levels on plasma cells. CD85a is a 631 amino acid type I transmembrane glycoprotein, which contains four immunoreceptor tyrosine-based inhibition motif (ITIM) sequences within a long cytoplasmic tail. Phosphorylation of the tyrosine residues within ITIMs is known to enable the binding and activation of protein tyrosine phosphatases, which act as cell signalling modulators and inhibitors of cell activation.
Content And Storage: Store at 4C in the dark.
Isotype: IgG1
Applications: Flow Cytometry, Immunohistochemistry, Immunohistochemistry (Frozen)
Clone: 4F9
Dilution: Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Frozen
Gene Alias: CD85 antigen-like family member A, CD85a antigen, HL9Immunoglobulin-like transcript 5, ILT-5, ILT5CD85a, Leukocyte immunoglobulin-like receptor 3, leukocyte immunoglobulin-like receptor subfamily B member 3, leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), LIR3CD85A, LIR-3MGC138403, member 3, Monocyte inhibitory receptor HL9, PIRB
Host Species: Mouse
Purification Method: Protein G purified
Regulatory Status: RUO
Gene ID (Entrez): 11025
Target Species: Human
Form: Purified
Antigen:
ILT5/CD85a/LILRB3
Classification:
Monoclonal
Conjugate:
DyLight 405
Formulation:
50mM Sodium Borate with 0.05% Sodium Azide
Gene Symbols:
LILRB3
Immunogen:
Monocyte derived dendritic cells
Quantity:
0.1 mL
Primary or Secondary:
Primary
Test Specificity:
NB100-64329 is specific for human CD85a (leucocyte immunoglobulin-like receptor, subfamily B, member 3/ LILRB3), also known as ILT-5, expressed by monocytes, dendritic cells, macrophages, subpopulation of T lymphocytes, B cells and at high levels on plasma cells. CD85a is a 631 amino acid type I transmembrane glycoprotein, which contains four immunoreceptor tyrosine-based inhibition motif (ITIM) sequences within a long cytoplasmic tail. Phosphorylation of the tyrosine residues within ITIMs is known to enable the binding and activation of protein tyrosine phosphatases, which act as cell signalling modulators and inhibitors of cell activation.
Content And Storage:
Store at 4C in the dark.
Isotype:
IgG1
Applications:
Flow Cytometry, Immunohistochemistry, Immunohistochemistry (Frozen)
Clone:
4F9
Dilution:
Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Frozen
Gene Alias:
CD85 antigen-like family member A, CD85a antigen, HL9Immunoglobulin-like transcript 5, ILT-5, ILT5CD85a, Leukocyte immunoglobulin-like receptor 3, leukocyte immunoglobulin-like receptor subfamily B member 3, leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), LIR3CD85A, LIR-3MGC138403, member 3, Monocyte inhibitory receptor HL9, PIRB
Host Species:
Mouse
Purification Method:
Protein G purified
Regulatory Status:
RUO
Gene ID (Entrez):
11025
Target Species:
Human
Form:
Purified
Antigen: Complement C6
Classification: Monoclonal
Conjugate: Unconjugated
Formulation: __
Gene Symbols: C6
Immunogen: Purified human C6
Quantity: 0.05 mg
Primary or Secondary: Primary
Test Specificity: NB100-64337 recognizes complement component 6 (C6), a 104 kDa member of the complement C6/C7/C8/C9 family present in blood serum. The factor I modules of C6 bind the C-terminus of the C5b alpha-chain, anchoring the molecule to the membrane; they also binds complement component 7. This enables the formation of the C5b-7 precursor complex. C5b-7 then functions as a receptor for components C8 and C9 which form the complement membrane attack complex (MAC). Deficiency of C6 results in susceptibility to bacterial infection. NB100-64337 recognizes MAC.
Content And Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Isotype: IgG1
Applications: Flow Cytometry, ELISA, Immunohistochemistry, Immunohistochemistry (Frozen)
Clone: 056B-214.2.4.2
Dilution: Flow Cytometry 1:10-1:1000, ELISA 1:100-1:2000, Immunohistochemistry 1:10-1:500, Immunohistochemistry-Frozen 1:10-1:500
Gene Alias: complement component 6, complement component C6
Host Species: Mouse
Purification Method: Protein A purified
Regulatory Status: RUO
Gene ID (Entrez): 729
Target Species: Human
Form: Purified
Antigen:
Complement C6
Classification:
Monoclonal
Conjugate:
Unconjugated
Formulation:
__
Gene Symbols:
C6
Immunogen:
Purified human C6
Quantity:
0.05 mg
Primary or Secondary:
Primary
Test Specificity:
NB100-64337 recognizes complement component 6 (C6), a 104 kDa member of the complement C6/C7/C8/C9 family present in blood serum. The factor I modules of C6 bind the C-terminus of the C5b alpha-chain, anchoring the molecule to the membrane; they also binds complement component 7. This enables the formation of the C5b-7 precursor complex. C5b-7 then functions as a receptor for components C8 and C9 which form the complement membrane attack complex (MAC). Deficiency of C6 results in susceptibility to bacterial infection. NB100-64337 recognizes MAC.
Content And Storage:
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Isotype:
IgG1
Applications:
Flow Cytometry, ELISA, Immunohistochemistry, Immunohistochemistry (Frozen)
Clone:
056B-214.2.4.2
Dilution:
Flow Cytometry 1:10-1:1000, ELISA 1:100-1:2000, Immunohistochemistry 1:10-1:500, Immunohistochemistry-Frozen 1:10-1:500
Gene Alias:
complement component 6, complement component C6
Host Species:
Mouse
Purification Method:
Protein A purified
Regulatory Status:
RUO
Gene ID (Entrez):
729
Target Species:
Human
Form:
Purified
Antigen: Complement C3c
Classification: Monoclonal
Conjugate: Unconjugated
Formulation: __
Gene Symbols: C3
Immunogen: Human C3 from normal serum, highly purified by chromatography.
Quantity: 0.05 mg
Primary or Secondary: Primary
Test Specificity: NB100-64339 recognizes 135 kDa complement component 3c (C3c), present in blood serum. C3c is generated over the course of complement activation, where convertase C4b2a (classical pathway) and convertase C3bBb (alternative pathway) cleave C3 to C3b and C3a. C3b is further degraded into iC3b and C3dg/C3d. iC3b is then slowly cleaved (possibly by factor I) to form C3c (beta chain + alpha' chain fragment 1 + alpha' chain fragment 2), C3dg and C3f. C3 is crucial in the induction of tolerance generated when an antigen is introduced into immunoprivileged sites and this is exploited by pathogens and cancer cells to evade the immune system by inhibiting complement activation.
Content And Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Isotype: IgG1
Applications: Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunohistochemistry (Frozen)
Clone: 10-02A
Dilution: Western Blot 1:100-1:2000, Flow Cytometry 1:10-1:1000, ELISA 1:100-1:2000, Immunohistochemistry 1:10-1:500, Immunohistochemistry-Frozen 1:10-1:500
Gene Alias: AHUS5, ARMD9, ASP, C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1, complement C3, complement component 3, complement component C3, CPAMD1acylation-stimulating protein cleavage product
Host Species: Mouse
Purification Method: Protein A purified
Regulatory Status: RUO
Gene ID (Entrez): 718
Target Species: Human
Form: Purified
Antigen:
Complement C3c
Classification:
Monoclonal
Conjugate:
Unconjugated
Formulation:
__
Gene Symbols:
C3
Immunogen:
Human C3 from normal serum, highly purified by chromatography.
Quantity:
0.05 mg
Primary or Secondary:
Primary
Test Specificity:
NB100-64339 recognizes 135 kDa complement component 3c (C3c), present in blood serum. C3c is generated over the course of complement activation, where convertase C4b2a (classical pathway) and convertase C3bBb (alternative pathway) cleave C3 to C3b and C3a. C3b is further degraded into iC3b and C3dg/C3d. iC3b is then slowly cleaved (possibly by factor I) to form C3c (beta chain + alpha' chain fragment 1 + alpha' chain fragment 2), C3dg and C3f. C3 is crucial in the induction of tolerance generated when an antigen is introduced into immunoprivileged sites and this is exploited by pathogens and cancer cells to evade the immune system by inhibiting complement activation.
Content And Storage:
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Isotype:
IgG1
Applications:
Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunohistochemistry (Frozen)
Clone:
10-02A
Dilution:
Western Blot 1:100-1:2000, Flow Cytometry 1:10-1:1000, ELISA 1:100-1:2000, Immunohistochemistry 1:10-1:500, Immunohistochemistry-Frozen 1:10-1:500
Gene Alias:
AHUS5, ARMD9, ASP, C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1, complement C3, complement component 3, complement component C3, CPAMD1acylation-stimulating protein cleavage product
Host Species:
Mouse
Purification Method:
Protein A purified
Regulatory Status:
RUO
Gene ID (Entrez):
718
Target Species:
Human
Form:
Purified
Antigen: Complement C8A/B/G
Classification: Monoclonal
Conjugate: Unconjugated
Formulation: __
Gene Symbols: C8A
Immunogen: Purified human C8
Quantity: 0.05 mg
Primary or Secondary: Primary
Test Specificity: This antibody recognizes complement component 8 (C8), a 151 kDa member of the complement C6/C7/C8/C9 family, present in blood serum. C8 is a terminal component of the complement system, part of both the complement membrane attack complex (MAC), and important to MAC assembly. C8 binds to the C5b-7 complex, anchored to the membrane, creating C5b-8. C5b-8 binds C9 and catalyzes the polymerization of C9 molecules to form C5-b9 (MAC). C8 is thought to contain lipid binding sites, facilitating the insertion of MAC into the membrane. Defects in the alpha chain of C8 can result in complement C8 deficiency type I. Furthermore, C8 deficiencies can cause recurring bacterial infections, in particular from Neisseria meningitides.
Content And Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Isotype: IgG1
Applications: Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunohistochemistry (Frozen)
Clone: 056B-373
Dilution: Western Blot 1:100-1:2000, Flow Cytometry 1:10-1:1000, ELISA 1:100-1:2000, Immunohistochemistry 1:10-1:500, Immunohistochemistry-Frozen 1:10-1:500
Gene Alias: complement component 8, alpha polypeptide, complement component C8 alpha chain
Host Species: Mouse
Purification Method: Protein A purified
Regulatory Status: RUO
Gene ID (Entrez): 731
Target Species: Human
Form: Purified
Antigen:
Complement C8A/B/G
Classification:
Monoclonal
Conjugate:
Unconjugated
Formulation:
__
Gene Symbols:
C8A
Immunogen:
Purified human C8
Quantity:
0.05 mg
Primary or Secondary:
Primary
Test Specificity:
This antibody recognizes complement component 8 (C8), a 151 kDa member of the complement C6/C7/C8/C9 family, present in blood serum. C8 is a terminal component of the complement system, part of both the complement membrane attack complex (MAC), and important to MAC assembly. C8 binds to the C5b-7 complex, anchored to the membrane, creating C5b-8. C5b-8 binds C9 and catalyzes the polymerization of C9 molecules to form C5-b9 (MAC). C8 is thought to contain lipid binding sites, facilitating the insertion of MAC into the membrane. Defects in the alpha chain of C8 can result in complement C8 deficiency type I. Furthermore, C8 deficiencies can cause recurring bacterial infections, in particular from Neisseria meningitides.
Content And Storage:
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Isotype:
IgG1
Applications:
Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunohistochemistry (Frozen)
Clone:
056B-373
Dilution:
Western Blot 1:100-1:2000, Flow Cytometry 1:10-1:1000, ELISA 1:100-1:2000, Immunohistochemistry 1:10-1:500, Immunohistochemistry-Frozen 1:10-1:500
Gene Alias:
complement component 8, alpha polypeptide, complement component C8 alpha chain
Host Species:
Mouse
Purification Method:
Protein A purified
Regulatory Status:
RUO
Gene ID (Entrez):
731
Target Species:
Human
Form:
Purified