NB10064358V

HLA DQ/DR/DP Antibody (WR18), DyLight 405, Novus Biologicals™

Manufacturer: Novus Biologicals

Select a Size

Pack Size SKU Availability Price
Each of 1 NB10064358V-Each-of-1 In Stock ₹ 54,245.04

NB10064358V - Each of 1

₹ 54,245.04

In Stock

Quantity

1

Base Price: ₹ 54,245.04

GST (18%): ₹ 9,764.107

Total Price: ₹ 64,009.147

Antigen

HLA DQ/DR/DP

Classification

Monoclonal

Conjugate

DyLight 405

Formulation

50mM Sodium Borate with 0.05% Sodium Azide

Gene Symbols

HLA-DQA1

Immunogen

Human HLA Class II (DP, DQ, DR)

Quantity

0.1 mL

Research Discipline

Adaptive Immunity, Asthma, Immunology

Gene ID (Entrez)

3117

Target Species

Human

Form

Purified

Applications

Flow Cytometry, Immunohistochemistry, Immunohistochemistry (Paraffin)

Clone

WR18

Dilution

Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Paraffin

Gene Alias

CD, CELIAC1DQ alpha 1 chain, DC-1 alpha chain, DQ-A1, FLJ27088, FLJ27328, GSE, HLA class II histocompatibility antigen, DQ(W3) alpha chain, HLA-DCA, HLA-DQA, leucocyte antigen DQA1, leukocyte antigen alpha chain, major histocompatibility complex, class II, DQ alpha 1, MGC149527, MHC class II antigen, MHC class II DQA1, MHC class II HLA-D alpha glycoprotein, MHC class II HLA-DQ-alpha-1, MHC class II surface glycoprotein, MHC HLA-DQ alpha

Host Species

Mouse

Purification Method

Protein G purified

Regulatory Status

RUO

Primary or Secondary

Primary

Test Specificity

Recognizes HLA Class II beta chains of human major histocompatability antigen, Mw 28 kD. It reacts with a monomorphic determinant common to each beta chain type. The antigen is expressed by human B lymphocytes, monocytes and activated T lymphocytes.

Content And Storage

Store at 4C in the dark.

Isotype

IgG2a

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Description

  • HLA DQ/DR/DP Monoclonal specifically detects HLA DQ/DR/DP in Human samples
  • It is validated for Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Paraffin.

Compare Similar Items

Show Difference

Img

Novus Biologicals

NB10064358V

--


Antigen:
HLA DQ/DR/DP

Classification:
Monoclonal

Conjugate:
DyLight 405

Formulation:
50mM Sodium Borate with 0.05% Sodium Azide

Gene Symbols:
HLA-DQA1

Immunogen:
Human HLA Class II (DP, DQ, DR)

Quantity:
0.1 mL

Research Discipline:
Adaptive Immunity, Asthma, Immunology

Gene ID (Entrez):
3117

Target Species:
Human

Form:
Purified

Applications:
Flow Cytometry, Immunohistochemistry, Immunohistochemistry (Paraffin)

Clone:
WR18

Dilution:
Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Paraffin

Gene Alias:
CD, CELIAC1DQ alpha 1 chain, DC-1 alpha chain, DQ-A1, FLJ27088, FLJ27328, GSE, HLA class II histocompatibility antigen, DQ(W3) alpha chain, HLA-DCA, HLA-DQA, leucocyte antigen DQA1, leukocyte antigen alpha chain, major histocompatibility complex, class II, DQ alpha 1, MGC149527, MHC class II antigen, MHC class II DQA1, MHC class II HLA-D alpha glycoprotein, MHC class II HLA-DQ-alpha-1, MHC class II surface glycoprotein, MHC HLA-DQ alpha

Host Species:
Mouse

Purification Method:
Protein G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
Recognizes HLA Class II beta chains of human major histocompatability antigen, Mw 28 kD. It reacts with a monomorphic determinant common to each beta chain type. The antigen is expressed by human B lymphocytes, monocytes and activated T lymphocytes.

Content And Storage:
Store at 4C in the dark.

Isotype:
IgG2a

Img

Fischer Scientific

NB10064359

--


Antigen:
SerpinB9

Classification:
Monoclonal

Conjugate:
Unconjugated

Formulation:
__

Gene Symbols:
SERPINB9

Immunogen:
Recombinant PI-9 produced in P. pastoris.

Quantity:
0.1 mg

Research Discipline:
Apoptosis, Immunology

Gene ID (Entrez):
5272

Target Species:
Human, Mouse (Negative), Porcine (Negative)

Form:
Purified

Applications:
Western Blot, Flow Cytometry, Immunohistochemistry, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen)

Clone:
7D8

Dilution:
Western Blot 1:100-1:2000, Flow Cytometry 1:10-1:100, Immunohistochemistry 1:10-1:500, Immunohistochemistry-Paraffin 1:50, Immunohistochemistry-Frozen 1:10-1:500

Gene Alias:
CAP-3, CAP3PI-9, Cytoplasmic antiproteinase 3, Peptidase inhibitor 9, PI9protease inhibitor 9 (ovalbumin type), serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 9, serpin B9, serpin peptidase inhibitor, clade B (ovalbumin), member 9, serpin peptidase inhibitor, clade B, member 9

Host Species:
Mouse

Purification Method:
Protein G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
NB100-64359 is specific for human PI-9 (proteinase inhibitor 9), also known as SerpinB9, a 42kDa intracellular nucleocytoplasmic serpin expressed in cytotoxic lymphocytes (CTLs), natural killer (NK) cells, monocyte-derived dendritic cells (DCs), and to a lesser extent in B cells and myeloid cells. Granzyme B (grB) is a serine protease highly expressed by CTLs and NK cells, which is endocytosed by virus-infected and malignant target cells. The subsequent release of grB from the endocytic vesicles into the cytoplasm of the target cells, triggers grB-mediated apoptosis, through cleavage of various cytoplasmic or nuclear proteins. PI-9, up-regulated in response to grB production and degranulation, has been identified as a potent inhibitor of Granzyme B-mediated apoptosis, providing a vital self-protection mechanism against the premature apoptosis of CTLs and NK cells by grB, which may escape into the cytoplasm of the effector cells themselves. Clone 7D8 detects a band of approximately 42kDa under reducing conditions. Clone 7D8 is suitable for use in indirect Immunofluorescence (2).

Content And Storage:
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Isotype:
IgG1

Img

Novus Biologicals

NB10064359C

--


Antigen:
SerpinB9

Classification:
Monoclonal

Conjugate:
DyLight 650

Formulation:
50 mM sodium borate with 0.05% sodium azide

Gene Symbols:
SERPINB9

Immunogen:
Recombinant PI-9 produced in P. pastoris.

Quantity:
0.1 mL

Research Discipline:
__

Gene ID (Entrez):
5272

Target Species:
Human, Mouse, Porcine

Form:
__

Applications:
Western Blot, Flow Cytometry, Immunohistochemistry, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen)

Clone:
7D8

Dilution:
Western Blot, Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen

Gene Alias:
CAP-3, CAP3PI-9, Cytoplasmic antiproteinase 3, Peptidase inhibitor 9, PI9protease inhibitor 9 (ovalbumin type), serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 9, serpin B9, serpin peptidase inhibitor, clade B (ovalbumin), member 9, serpin peptidase inhibitor, clade B, member 9

Host Species:
Mouse

Purification Method:
__

Regulatory Status:
__

Primary or Secondary:
Primary

Test Specificity:
NB100-64359 is specific for human PI-9 (proteinase inhibitor 9), also known as SerpinB9, a 42kDa intracellular nucleocytoplasmic serpin expressed in cytotoxic lymphocytes (CTLs), natural killer (NK) cells, monocyte-derived dendritic cells (DCs), and to a lesser extent in B cells and myeloid cells. Granzyme B (grB) is a serine protease highly expressed by CTLs and NK cells, which is endocytosed by virus-infected and malignant target cells. The subsequent release of grB from the endocytic vesicles into the cytoplasm of the target cells, triggers grB-mediated apoptosis, through cleavage of various cytoplasmic or nuclear proteins. PI-9, up-regulated in response to grB production and degranulation, has been identified as a potent inhibitor of Granzyme B-mediated apoptosis, providing a vital self-protection mechanism against the premature apoptosis of CTLs and NK cells by grB, which may escape into the cytoplasm of the effector cells themselves. Clone 7D8 detects a band of approximately 42kD

Content And Storage:
Store at 4°C in the dark.

Isotype:
IgG1

Img

Novus Biologicals

NB10064359G

--


Antigen:
SerpinB9

Classification:
Monoclonal

Conjugate:
DyLight 488

Formulation:
__

Gene Symbols:
SERPINB9

Immunogen:
Recombinant PI-9 produced in P. pastoris.

Quantity:
0.1 mL

Research Discipline:
Apoptosis, Immunology

Gene ID (Entrez):
5272

Target Species:
Human, Mouse (Negative), Porcine (Negative)

Form:
Purified

Applications:
Western Blot, Flow Cytometry, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen)

Clone:
7D8

Dilution:
Western Blot, Flow Cytometry, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen

Gene Alias:
CAP-3, CAP3PI-9, Cytoplasmic antiproteinase 3, Peptidase inhibitor 9, PI9protease inhibitor 9 (ovalbumin type), serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 9, serpin B9, serpin peptidase inhibitor, clade B (ovalbumin), member 9, serpin peptidase inhibitor, clade B, member 9

Host Species:
Mouse

Purification Method:
Protein G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
NB100-64359 is specific for human PI-9 (proteinase inhibitor 9), also known as SerpinB9, a 42kDa intracellular nucleocytoplasmic serpin expressed in cytotoxic lymphocytes (CTLs), natural killer (NK) cells, monocyte-derived dendritic cells (DCs), and to a lesser extent in B cells and myeloid cells. Granzyme B (grB) is a serine protease highly expressed by CTLs and NK cells, which is endocytosed by virus-infected and malignant target cells. The subsequent release of grB from the endocytic vesicles into the cytoplasm of the target cells, triggers grB-mediated apoptosis, through cleavage of various cytoplasmic or nuclear proteins. PI-9, up-regulated in response to grB production and degranulation, has been identified as a potent inhibitor of Granzyme B-mediated apoptosis, providing a vital self-protection mechanism against the premature apoptosis of CTLs and NK cells by grB, which may escape into the cytoplasm of the effector cells themselves. Clone 7D8 detects a band of approximately 42kD

Content And Storage:
Store at 4C in the dark.

Isotype:
IgG1