NB10065388S

L-Selectin/CD62L Antibody (FMC46), DyLight 550, Novus Biologicals™

Manufacturer: Novus Biologicals

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Pack Size SKU Availability Price
Each of 1 NB10065388S-Each-of-1 In Stock ₹ 52,191.60

NB10065388S - Each of 1

₹ 52,191.60

In Stock

Quantity

1

Base Price: ₹ 52,191.60

GST (18%): ₹ 9,394.488

Total Price: ₹ 61,586.088

Antigen

L-Selectin/CD62L

Classification

Monoclonal

Conjugate

DyLight 550

Formulation

50 mM sodium borate with 0.05% sodium azide

Gene Symbols

SELL

Immunogen

PHA stimulated lymphoblasts.

Quantity

0.1 mL

Primary or Secondary

Primary

Test Specificity

NB100-65388 recognizes human CD62L, also known a L-selectin, a 74-95kDa member of the selectin family of adhesion receptors, which acts as a ligand for both CD62-P (P-selectin) and CD62E (E-selectin). Human CD62L is constitutively expressed on most leucocytes including monocytes, granulocytes, lymphocytes, NK cells, bone marrow myeloid progenitor cells and on a subset of thymocytes. CD62L plays an important role in leucocyte tethering and rolling on the endothelial cell surface and for the homing of naive lymphocytes to lymph nodes and Peyers patches via HEV. Neutrophils require a constant supply of this molecule on the cell surface for migration into peripheral tissues and adhesion to activated endothelium at sites of inflammation, where CD62L is rapidly shed as soluble L-selectin, but surface expression still remains. The expression of CD62L is down regulated on lymphocytes and neutrophils by PMA stimulation.

Content And Storage

Store at 4°C in the dark.

Applications

Flow Cytometry, Immunohistochemistry, Immunohistochemistry (Frozen)

Clone

FMC46

Dilution

Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Frozen

Gene Alias

CD62L, CD62L antigen, gp90-MEL, hLHRc, LAM-1, LAM1LECAM1, Leu-8, LEU8, Leukocyte adhesion molecule 1, Leukocyte surface antigen Leu-8, Leukocyte-endothelial cell adhesion molecule 1, LNHRTQ1, LSEL, L-selectin, Lyam-1, LYAM1CD62 antigen-like family member L, Lymph node homing receptor, lymphocyte adhesion molecule 1, pln homing receptor, PLNHR, selectin L

Host Species

Mouse

Purification Method

Protein G purified

Research Discipline

Adaptive Immunity, B Cell Development and Differentiation Markers, Cardiovascular Biology, Glycobiology, Immunology, Lipid and Metabolism, Myeloid derived Suppressor Cell, Signal Transduction, Stem Cells

Gene ID (Entrez)

6402.0

Target Species

Human, Bovine, Canine, Primate

Isotype

IgG2b

Description

  • Description L-Selectin/CD62L Monoclonal specifically detects L-Selectin/CD62L in Human, Bovine, Canine, Primate samples
  • It is validated for Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Frozen.

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Img

Novus Biologicals

NB10065388S

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Antigen:
L-Selectin/CD62L

Classification:
Monoclonal

Conjugate:
DyLight 550

Formulation:
50 mM sodium borate with 0.05% sodium azide

Gene Symbols:
SELL

Immunogen:
PHA stimulated lymphoblasts.

Quantity:
0.1 mL

Primary or Secondary:
Primary

Test Specificity:
NB100-65388 recognizes human CD62L, also known a L-selectin, a 74-95kDa member of the selectin family of adhesion receptors, which acts as a ligand for both CD62-P (P-selectin) and CD62E (E-selectin). Human CD62L is constitutively expressed on most leucocytes including monocytes, granulocytes, lymphocytes, NK cells, bone marrow myeloid progenitor cells and on a subset of thymocytes. CD62L plays an important role in leucocyte tethering and rolling on the endothelial cell surface and for the homing of naive lymphocytes to lymph nodes and Peyers patches via HEV. Neutrophils require a constant supply of this molecule on the cell surface for migration into peripheral tissues and adhesion to activated endothelium at sites of inflammation, where CD62L is rapidly shed as soluble L-selectin, but surface expression still remains. The expression of CD62L is down regulated on lymphocytes and neutrophils by PMA stimulation.

Content And Storage:
Store at 4°C in the dark.

Applications:
Flow Cytometry, Immunohistochemistry, Immunohistochemistry (Frozen)

Clone:
FMC46

Dilution:
Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Frozen

Gene Alias:
CD62L, CD62L antigen, gp90-MEL, hLHRc, LAM-1, LAM1LECAM1, Leu-8, LEU8, Leukocyte adhesion molecule 1, Leukocyte surface antigen Leu-8, Leukocyte-endothelial cell adhesion molecule 1, LNHRTQ1, LSEL, L-selectin, Lyam-1, LYAM1CD62 antigen-like family member L, Lymph node homing receptor, lymphocyte adhesion molecule 1, pln homing receptor, PLNHR, selectin L

Host Species:
Mouse

Purification Method:
Protein G purified

Research Discipline:
Adaptive Immunity, B Cell Development and Differentiation Markers, Cardiovascular Biology, Glycobiology, Immunology, Lipid and Metabolism, Myeloid derived Suppressor Cell, Signal Transduction, Stem Cells

Gene ID (Entrez):
6402.0

Target Species:
Human, Bovine, Canine, Primate

Isotype:
IgG2b

Img

Novus Biologicals

NB10065388U

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Antigen:
L-Selectin/CD62L

Classification:
Monoclonal

Conjugate:
DyLight 350

Formulation:
__

Gene Symbols:
SELL

Immunogen:
PHA stimulated lymphoblasts.

Quantity:
0.1 mL

Primary or Secondary:
Primary

Test Specificity:
NB100-65388 recognizes human CD62L, also known a L-selectin, a 74-95kDa member of the selectin family of adhesion receptors, which acts as a ligand for both CD62-P (P-selectin) and CD62E (E-selectin). Human CD62L is constitutively expressed on most leucocytes including monocytes, granulocytes, lymphocytes, NK cells, bone marrow myeloid progenitor cells and on a subset of thymocytes. CD62L plays an important role in leucocyte tethering and rolling on the endothelial cell surface and for the homing of naive lymphocytes to lymph nodes and Peyers patches via HEV. Neutrophils require a constant supply of this molecule on the cell surface for migration into peripheral tissues and adhesion to activated endothelium at sites of inflammation, where CD62L is rapidly shed as soluble L-selectin, but surface expression still remains. The expression of CD62L is down regulated on lymphocytes and neutrophils by PMA stimulation.

Content And Storage:
Store at 4C in the dark.

Applications:
Flow Cytometry, Immunohistochemistry, Immunohistochemistry (Frozen)

Clone:
FMC46

Dilution:
Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Frozen

Gene Alias:
CD62L, CD62L antigen, gp90-MEL, hLHRc, LAM-1, LAM1LECAM1, Leu-8, LEU8, Leukocyte adhesion molecule 1, Leukocyte surface antigen Leu-8, Leukocyte-endothelial cell adhesion molecule 1, LNHRTQ1, LSEL, L-selectin, Lyam-1, LYAM1CD62 antigen-like family member L, Lymph node homing receptor, lymphocyte adhesion molecule 1, pln homing receptor, PLNHR, selectin L

Host Species:
Mouse

Purification Method:
Protein G purified

Research Discipline:
Adaptive Immunity, B Cell Development and Differentiation Markers, Cardiovascular Biology, Glycobiology, Immunology, Lipid and Metabolism, Myeloid derived Suppressor Cell, Signal Transduction, Stem Cells

Gene ID (Entrez):
6402

Target Species:
Human, Bovine, Canine, Primate

Isotype:
IgG2b

Img

Novus Biologicals

NB10065388Z

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Antigen:
L-Selectin/CD62L

Classification:
Monoclonal

Conjugate:
Alexa Fluor 700

Formulation:
50mM Sodium Borate with 0.05% Sodium Azide

Gene Symbols:
SELL

Immunogen:
PHA stimulated lymphoblasts.

Quantity:
0.1 mL

Primary or Secondary:
Primary

Test Specificity:
NB100-65388 recognizes human CD62L, also known a L-selectin, a 74-95kDa member of the selectin family of adhesion receptors, which acts as a ligand for both CD62-P (P-selectin) and CD62E (E-selectin). Human CD62L is constitutively expressed on most leucocytes including monocytes, granulocytes, lymphocytes, NK cells, bone marrow myeloid progenitor cells and on a subset of thymocytes. CD62L plays an important role in leucocyte tethering and rolling on the endothelial cell surface and for the homing of naive lymphocytes to lymph nodes and Peyers patches via HEV. Neutrophils require a constant supply of this molecule on the cell surface for migration into peripheral tissues and adhesion to activated endothelium at sites of inflammation, where CD62L is rapidly shed as soluble L-selectin, but surface expression still remains. The expression of CD62L is down regulated on lymphocytes and neutrophils by PMA stimulation.

Content And Storage:
Store at 4C in the dark.

Applications:
Flow Cytometry, Immunohistochemistry, Immunohistochemistry (Frozen)

Clone:
FMC46

Dilution:
Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Frozen

Gene Alias:
CD62L, CD62L antigen, gp90-MEL, hLHRc, LAM-1, LAM1LECAM1, Leu-8, LEU8, Leukocyte adhesion molecule 1, Leukocyte surface antigen Leu-8, Leukocyte-endothelial cell adhesion molecule 1, LNHRTQ1, LSEL, L-selectin, Lyam-1, LYAM1CD62 antigen-like family member L, Lymph node homing receptor, lymphocyte adhesion molecule 1, pln homing receptor, PLNHR, selectin L

Host Species:
Mouse

Purification Method:
Protein G purified

Research Discipline:
Adaptive Immunity, B Cell Development and Differentiation Markers, Cardiovascular Biology, Glycobiology, Immunology, Lipid and Metabolism, Myeloid derived Suppressor Cell, Signal Transduction, Stem Cells

Gene ID (Entrez):
6402

Target Species:
Human, Bovine, Canine, Primate

Isotype:
IgG2b

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Fischer Scientific

NB10065391

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Antigen:
P-Selectin/CD62P

Classification:
Monoclonal

Conjugate:
Unconjugated

Formulation:
__

Gene Symbols:
SELP

Immunogen:
P-Selectin transfected 300.19 cells.

Quantity:
0.1 mg

Primary or Secondary:
Primary

Test Specificity:
NB100-65391 recognizes the P-Selectin cell surface antigen, a 140kD glycoprotein. P-Selectin is expressed by activated platelets and endothelial cells, and plays an important role in adhesive processes between leucocytes and endothelial cells. Clone Psel.KO.2.12 is reported to inhibit P-selectin-dependent adhesion between HL60 cells and P-selectin transfected COS cells.

Content And Storage:
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Applications:
Flow Cytometry, Immunohistochemistry, Immunoprecipitation, Immunohistochemistry (Frozen)

Clone:
Psel.KO.2.12

Dilution:
Flow Cytometry 1:50-1:100, Immunohistochemistry 1:10-1:500, Immunoprecipitation 1:10-1:500, Immunohistochemistry-Frozen 1:10-1:500

Gene Alias:
CD62P antigen, FLJ45155, PADGEMantigen CD62), selectin P (granule membrane protein 140kDa, antigen CD62)

Host Species:
Mouse

Purification Method:
Protein G purified

Research Discipline:
__

Gene ID (Entrez):
6403

Target Species:
Human, Rat, Goat, Sheep

Isotype:
IgG1