NB20100UG

MilliporeSigma™ anti-AnkyrinG Clone: 463,

Manufacturer: MilliporeSigma™

Select a Size

Pack Size SKU Availability Price
Each of 1 NB20100UG-Each-of-1 In Stock ₹ 43,707.47

NB20100UG - Each of 1

₹ 43,707.47

In Stock

Quantity

1

Base Price: ₹ 43,707.47

GST (18%): ₹ 7,867.345

Total Price: ₹ 51,574.815

Antigen

AnkyrinG

Classification

Monoclonal

Conjugate

Unconjugated

Host Species

Mouse

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Canine, Human, Mouse, Rat

Form

Purified

Applications

Immunoblot, Immunofluorescence, Immunohistochemistry (Frozen)

Clone

463

Formulation

In 50mM sodium phosphate buffer, 0.2% gelatin, pH 7.5.

Immunogen

a synthetic peptide corresponding to amino acids from the spectrin-binding domain of human ankyrinG

Regulatory Status

RUO

Test Specificity

Recognizes the ∽190kDa ankyrinGprotein in brain extracts. Reacts with all spliced forms of ankyrinG. Antibody Target Gene Symbol: ANK3 Target Synonym: 2900054D09RIK, AI314020, AnkG, Ankyrin-3, ANKYRIN-G, FLJ45464, MGC14049 Entrez Gene Name: ankyrin 3, node of Ranvier (ankyrin G)

Content And Storage

2°C to 8°C

Isotype

IgG1

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Description

  • Specifically detects Ankyrin G Clone: 463 in Canine, Human, Mouse, Rat samples, and it is validated for Immunofluorescence, Immunohistochemistry (Frozen), Immuno Blotting Ankyrins are a family of spectrin-binding proteins that couple the spectrin/actin cytoskeletal network to the cytoplasmic domains of integral membrane proteins which include channels such as the anion exchanger, voltage-dependent sodium channel, and the Na/K ATPase, as well as neuronal cell adhesion molecules related to L1
  • In the nervous system, three different ankyrins are known to exist; ankyrin B , ankyrin G , and ankyrin R
  • All three ankyrins contain an N-terminal membrane binding domain, an internal domain capable of binding spectrin, and a C-terminal regulatory domain which is the target of alternative splicing
  • AnkyrinB, the predominant neuronal ankyrin includes two isoforms of ∽220kDa and ∽440kDa
  • The ∽220kDa alternatively spliced isoform is the major form present in the adult brain, while the ∽440kDa form is preferentially expressed in the developing neonatal brain
  • Three forms of ankyrinG (∽190kDa, ∽270kDa, ∽480kDa) are localized in axonal initial segments and the nodes of Ranvier of myelinated axons where fluxes of action potential occur and ion channels are enriched
  • Ankyrins comprise ∽0.5%-1% of the total membrane protein in the adult vertebrate brain.

Compare Similar Items

Show Difference

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MilliporeSigma™

NB20100UG

--


Antigen:
AnkyrinG

Classification:
Monoclonal

Conjugate:
Unconjugated

Host Species:
Mouse

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Canine, Human, Mouse, Rat

Form:
Purified

Applications:
Immunoblot, Immunofluorescence, Immunohistochemistry (Frozen)

Clone:
463

Formulation:
In 50mM sodium phosphate buffer, 0.2% gelatin, pH 7.5.

Immunogen:
a synthetic peptide corresponding to amino acids from the spectrin-binding domain of human ankyrinG

Regulatory Status:
RUO

Test Specificity:
Recognizes the ∽190kDa ankyrinGprotein in brain extracts. Reacts with all spliced forms of ankyrinG. Antibody Target Gene Symbol: ANK3 Target Synonym: 2900054D09RIK, AI314020, AnkG, Ankyrin-3, ANKYRIN-G, FLJ45464, MGC14049 Entrez Gene Name: ankyrin 3, node of Ranvier (ankyrin G)

Content And Storage:
2°C to 8°C

Isotype:
IgG1

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Novus Biologicals

NB201010

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Antigen:
COMMD7

Classification:
Polyclonal

Conjugate:
Alexa Fluor 405

Host Species:
Rabbit

Quantity:
0.1 mL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Form:
Purified

Applications:
Western Blot, ELISA, Immunohistochemistry, Immunohistochemistry (Paraffin)

Clone:
__

Formulation:
50mM Sodium Borate

Immunogen:
Antibody was raised against a 19 amino acid peptide near the center of human COMMD7. The immunogen is located within amino acids 90 - 140 of COMMD7. Amino Acid Squence: LSEEKATYFSEKWKQNAPT

Regulatory Status:
RUO

Test Specificity:
__

Content And Storage:
Store at 4°C in the dark.

Isotype:
IgG

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Novus Biologicals

NB201011

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Antigen:
SLC29A4

Classification:
Polyclonal

Conjugate:
Janelia Fluor 549

Host Species:
Rabbit

Quantity:
0.1 mL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Purified

Applications:
Western Blot, ELISA, Immunohistochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)

Clone:
__

Formulation:
50mM Sodium Borate

Immunogen:
Antibody was raised against an 18 amino acid peptide near the center of human SLC29A4. The immunogen is located within amino acids 310 - 360 of SLC29A4. Amino Acid Squence: MRFDVPRPRVQRSWPTFR

Regulatory Status:
RUO

Test Specificity:
__

Content And Storage:
Store at 4°C in the dark.

Isotype:
IgG

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Novus Biologicals

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Antigen:
TMEPAI

Classification:
Polyclonal

Conjugate:
Alexa Fluor 350

Host Species:
Rabbit

Quantity:
0.1 mL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Form:
Purified

Applications:
Western Blot, ELISA, Immunohistochemistry, Immunohistochemistry (Paraffin)

Clone:
__

Formulation:
50mM Sodium Borate

Immunogen:
Antibody was raised against a 16 amino acid peptide near the center of human PMEPA1. The immunogen is located within amino acids 160 - 210 of PMEPA1. Amino Acid Squence: QLELNRESVRAPPNRT

Regulatory Status:
RUO

Test Specificity:
__

Content And Storage:
Store at 4°C in the dark.

Isotype:
IgG