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NB247670APC

HLA-DR Antibody (LN-3), Allophycocyanin, Novus Biologicals™

Manufacturer: Novus Biologicals

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Pack Size SKU Availability Price
Each of 1 NB247670APC-Each-of-1 In Stock ₹ 54,245.04

NB247670APC - Each of 1

₹ 54,245.04

In Stock

Quantity

1

Base Price: ₹ 54,245.04

GST (18%): ₹ 9,764.107

Total Price: ₹ 64,009.147

Antigen

HLA-DR

Classification

Monoclonal

Conjugate

APC

Formulation

PBS with 0.05% Sodium Azide

Gene Symbols

HLA-DRA

Immunogen

Activated human peripheral blood mononuclear cells

Quantity

0.1 mL

Primary or Secondary

Primary

Test Specificity

This monoclonal antibody reacts with a 28kDa chain of HLA-DRB1 antigen, a member of MHC class II molecules. It does not cross react with HLA-DP and HLA-DQ. The L243 antibody recognizes a different epitope than the LN3 monoclonal antibody, and these antibodies do not cross-block binding to each others respective epitopes. HLA-DR is a heterodimeric cell surface glycoprotein comprised of a 36kDa alpha (heavy) chain and a 28kDa beta (light) chain. It is expressed on B-cells, activated T-cells, monocytes/macrophages, dendritic cells and other non-professional APCs. In conjunction with the CD3/TCR complex and CD4 molecules, HLA-DR is critical for efficient peptide presentation to CD4+ T cells. It is an excellent histiocytic marker in paraffin sections producing intense staining. True histiocytic neoplasms are similarly positive. HLA-DR antigens also occur on a variety of epithelial cells and their corresponding neoplastic counterparts. Loss of HLA-DR expression is related to tumor microenvironment and predicts adverse outcome in diffuse large B-cell lymphoma.

Content And Storage

Store at 4C in the dark.

Isotype

IgG2b κ

Applications

Flow Cytometry

Clone

LN-3

Dilution

Flow Cytometry

Gene Alias

FLJ51114, histocompatibility antigen HLA-DR alpha, HLA class II histocompatibility antigen, DR alpha chain, HLA-DRA1, major histocompatibility complex, class II, DR alpha, MHC cell surface glycoprotein, MHC class II antigen DRA, MLRW

Host Species

Mouse

Purification Method

Protein A or G purified

Research Discipline

Adaptive Immunity, B Cell Development and Differentiation Markers, Cell Biology, Cellular Markers, Diabetes Research, Immunology, Major Histocompatibility Complexes

Gene ID (Entrez)

3122

Target Species

Human, Monkey, Mouse (Negative)

Form

Purified

Description

  • HLA-DR Monoclonal specifically detects HLA-DR in Human, Monkey, Mouse (Negative) samples
  • It is validated for Flow Cytometry.

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Img

Novus Biologicals

NB247670APC

--

Antigen:
HLA-DR
Classification:
Monoclonal
Conjugate:
APC
Formulation:
PBS with 0.05% Sodium Azide
Gene Symbols:
HLA-DRA
Immunogen:
Activated human peripheral blood mononuclear cells
Quantity:
0.1 mL
Primary or Secondary:
Primary
Test Specificity:
This monoclonal antibody reacts with a 28kDa chain of HLA-DRB1 antigen, a member of MHC class II molecules. It does not cross react with HLA-DP and HLA-DQ. The L243 antibody recognizes a different epitope than the LN3 monoclonal antibody, and these antibodies do not cross-block binding to each others respective epitopes. HLA-DR is a heterodimeric cell surface glycoprotein comprised of a 36kDa alpha (heavy) chain and a 28kDa beta (light) chain. It is expressed on B-cells, activated T-cells, monocytes/macrophages, dendritic cells and other non-professional APCs. In conjunction with the CD3/TCR complex and CD4 molecules, HLA-DR is critical for efficient peptide presentation to CD4+ T cells. It is an excellent histiocytic marker in paraffin sections producing intense staining. True histiocytic neoplasms are similarly positive. HLA-DR antigens also occur on a variety of epithelial cells and their corresponding neoplastic counterparts. Loss of HLA-DR expression is related to tumor microenvironment and predicts adverse outcome in diffuse large B-cell lymphoma.
Content And Storage:
Store at 4C in the dark.
Isotype:
IgG2b κ
Applications:
Flow Cytometry
Clone:
LN-3
Dilution:
Flow Cytometry
Gene Alias:
FLJ51114, histocompatibility antigen HLA-DR alpha, HLA class II histocompatibility antigen, DR alpha chain, HLA-DRA1, major histocompatibility complex, class II, DR alpha, MHC cell surface glycoprotein, MHC class II antigen DRA, MLRW
Host Species:
Mouse
Purification Method:
Protein A or G purified
Research Discipline:
Adaptive Immunity, B Cell Development and Differentiation Markers, Cell Biology, Cellular Markers, Diabetes Research, Immunology, Major Histocompatibility Complexes
Gene ID (Entrez):
3122
Target Species:
Human, Monkey, Mouse (Negative)
Form:
Purified

Img

Novus Biologicals

NB247670PCP

--

Antigen:
HLA-DR
Classification:
Monoclonal
Conjugate:
PerCP
Formulation:
PBS with 0.05% Sodium Azide
Gene Symbols:
HLA-DRA
Immunogen:
Activated human peripheral blood mononuclear cells
Quantity:
0.1 mL
Primary or Secondary:
Primary
Test Specificity:
This monoclonal antibody reacts with a 28kDa chain of HLA-DRB1 antigen, a member of MHC class II molecules. It does not cross react with HLA-DP and HLA-DQ. The L243 antibody recognizes a different epitope than the LN3 monoclonal antibody, and these antibodies do not cross-block binding to each others respective epitopes. HLA-DR is a heterodimeric cell surface glycoprotein comprised of a 36kDa alpha (heavy) chain and a 28kDa beta (light) chain. It is expressed on B-cells, activated T-cells, monocytes/macrophages, dendritic cells and other non-professional APCs. In conjunction with the CD3/TCR complex and CD4 molecules, HLA-DR is critical for efficient peptide presentation to CD4+ T cells. It is an excellent histiocytic marker in paraffin sections producing intense staining. True histiocytic neoplasms are similarly positive. HLA-DR antigens also occur on a variety of epithelial cells and their corresponding neoplastic counterparts. Loss of HLA-DR expression is related to tumor microenvironment and predicts adverse outcome in diffuse large B-cell lymphoma.
Content And Storage:
Store at 4C in the dark.
Isotype:
IgG2b κ
Applications:
Flow Cytometry
Clone:
LN-3
Dilution:
Flow Cytometry
Gene Alias:
FLJ51114, histocompatibility antigen HLA-DR alpha, HLA class II histocompatibility antigen, DR alpha chain, HLA-DRA1, major histocompatibility complex, class II, DR alpha, MHC cell surface glycoprotein, MHC class II antigen DRA, MLRW
Host Species:
Mouse
Purification Method:
Protein A or G purified
Research Discipline:
Adaptive Immunity, B Cell Development and Differentiation Markers, Cell Biology, Cellular Markers, Diabetes Research, Immunology, Major Histocompatibility Complexes
Gene ID (Entrez):
3122
Target Species:
Human, Monkey, Mouse (Negative)
Form:
Purified

Img

Novus Biologicals

NB247671

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Antigen:
Anillin
Classification:
Polyclonal
Conjugate:
Biotin
Formulation:
PBS
Gene Symbols:
__
Immunogen:
The immunogen recognized by this antibody maps to a region between residue 1074 and 1124 of human actin binding protein Anillin using the numbering given in entry NP_061155.2 (GeneID 54443).
Quantity:
0.1 mL
Primary or Secondary:
Primary
Test Specificity:
__
Content And Storage:
Store at 4C in the dark.
Isotype:
IgG
Applications:
Western Blot, Immunohistochemistry, Immunohistochemistry (Paraffin)
Clone:
__
Dilution:
Western Blot, Immunohistochemistry, Immunohistochemistry-Paraffin
Gene Alias:
actin-binding protein anillin, ANILLIN, anillin (Drosophila Scraps homolog), actin binding protein, anillin, actin binding protein, anillin, actin binding protein (scraps homolog, Drosophila), DKFZp779A055, Drosophila Scraps homolog, scra, Scraps
Host Species:
Rabbit
Purification Method:
Immunogen affinity purified
Research Discipline:
__
Gene ID (Entrez):
54443
Target Species:
Human
Form:
Purified

Img

Novus Biologicals

NB247672

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Antigen:
NIPBL
Classification:
Polyclonal
Conjugate:
DyLight 650
Formulation:
50mM Sodium Borate
Gene Symbols:
__
Immunogen:
The immunogen recognized by this antibody maps to a region between residue 1025 and 1075 of human Nipped-B-like using the numbering given in entry NP_597677.2 (GeneID 25836).
Quantity:
0.1 mL
Primary or Secondary:
Primary
Test Specificity:
__
Content And Storage:
Store at 4C in the dark.
Isotype:
IgG
Applications:
Western Blot
Clone:
__
Dilution:
Western Blot
Gene Alias:
CDLS1, delangin, DKFZp434L1319, FLJ11203, FLJ12597, FLJ13354, FLJ13648, FLJ44854, IDN3-B, IDN3CDLS, Nipped-B homolog (Drosophila), nipped-B-like protein, Scc2, SCC2 homolog, sister chromatid cohesion 2 homolog
Host Species:
Rabbit
Purification Method:
Immunogen affinity purified
Research Discipline:
Cell Cycle and Replication
Gene ID (Entrez):
25836
Target Species:
Human
Form:
Purified