NB253243200
Filaggrin Antibody (FLG/1561), Novus Biologicals™
Manufacturer: Fischer Scientific
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Antigen
Filaggrin
Classification
Monoclonal
Concentration
0.2 mg/mL
Dilution
Flow Cytometry 0.5 - 1 ug/million cells, Immunocytochemistry/Immunofluorescence 1 - 2 ug/ml, Immunohistochemistry-Paraffin 0.5 - 1.0 ug/ml, SDS-Page
Gene Alias
ATOD2, epidermal filaggrin, filaggrin, Profilaggrin
Host Species
Mouse
Purification Method
Protein A or G purified
Regulatory Status
RUO
Primary or Secondary
Primary
Test Specificity
Filaggrin is an intermediate filament-associated protein that aggregates keratin intermediate filaments in mammalian epidermis. It is initially synthesized as a polyprotein precursor, profilaggrin (consisting of multiple filaggrin units of 324 aa each), which is localized in keratohyalin granules, and is subsequently proteolytically processed into individual functional filaggrin molecules. Active filaggrin is present at a level of the epidermis where keratinocytes are in transition between the live nucleated granular layer and the anucleate cornified layer, suggesting that filaggrin aids in the terminal differentiation process by facilitating apoptotic machinery
Content And Storage
Store at 4C.
Isotype
IgG1
Applications
Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), SDS-Page
Clone
FLG/1561
Conjugate
Unconjugated
Formulation
10mM PBS with 0.05% BSA with 0.05% Sodium Azide
Gene Symbols
FLG
Immunogen
Recombinant human Filaggrin protein fragment (aa 198-288) (exact sequence is proprietary)
Quantity
200 μg
Research Discipline
Cytoskeleton Markers
Gene ID (Entrez)
2312
Target Species
Human
Form
Purified
Related Products
Description
- Filaggrin Monoclonal specifically detects Filaggrin in Human samples
- It is validated for Immunohistochemistry, Immunohistochemistry-Paraffin, Protein Array.
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Antigen: Filaggrin
Classification: Monoclonal
Concentration: 0.2 mg/mL
Dilution: Flow Cytometry 0.5 - 1 ug/million cells, Immunocytochemistry/Immunofluorescence 1 - 2 ug/ml, Immunohistochemistry-Paraffin 0.5 - 1.0 ug/ml, SDS-Page
Gene Alias: ATOD2, epidermal filaggrin, filaggrin, Profilaggrin
Host Species: Mouse
Purification Method: Protein A or G purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: Filaggrin is an intermediate filament-associated protein that aggregates keratin intermediate filaments in mammalian epidermis. It is initially synthesized as a polyprotein precursor, profilaggrin (consisting of multiple filaggrin units of 324 aa each), which is localized in keratohyalin granules, and is subsequently proteolytically processed into individual functional filaggrin molecules. Active filaggrin is present at a level of the epidermis where keratinocytes are in transition between the live nucleated granular layer and the anucleate cornified layer, suggesting that filaggrin aids in the terminal differentiation process by facilitating apoptotic machinery
Content And Storage: Store at 4C.
Isotype: IgG1
Applications: Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), SDS-Page
Clone: FLG/1561
Conjugate: Unconjugated
Formulation: 10mM PBS with 0.05% BSA with 0.05% Sodium Azide
Gene Symbols: FLG
Immunogen: Recombinant human Filaggrin protein fragment (aa 198-288) (exact sequence is proprietary)
Quantity: 200 μg
Research Discipline: Cytoskeleton Markers
Gene ID (Entrez): 2312
Target Species: Human
Form: Purified
Antigen:
Filaggrin
Classification:
Monoclonal
Concentration:
0.2 mg/mL
Dilution:
Flow Cytometry 0.5 - 1 ug/million cells, Immunocytochemistry/Immunofluorescence 1 - 2 ug/ml, Immunohistochemistry-Paraffin 0.5 - 1.0 ug/ml, SDS-Page
Gene Alias:
ATOD2, epidermal filaggrin, filaggrin, Profilaggrin
Host Species:
Mouse
Purification Method:
Protein A or G purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
Filaggrin is an intermediate filament-associated protein that aggregates keratin intermediate filaments in mammalian epidermis. It is initially synthesized as a polyprotein precursor, profilaggrin (consisting of multiple filaggrin units of 324 aa each), which is localized in keratohyalin granules, and is subsequently proteolytically processed into individual functional filaggrin molecules. Active filaggrin is present at a level of the epidermis where keratinocytes are in transition between the live nucleated granular layer and the anucleate cornified layer, suggesting that filaggrin aids in the terminal differentiation process by facilitating apoptotic machinery
Content And Storage:
Store at 4C.
Isotype:
IgG1
Applications:
Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), SDS-Page
Clone:
FLG/1561
Conjugate:
Unconjugated
Formulation:
10mM PBS with 0.05% BSA with 0.05% Sodium Azide
Gene Symbols:
FLG
Immunogen:
Recombinant human Filaggrin protein fragment (aa 198-288) (exact sequence is proprietary)
Quantity:
200 μg
Research Discipline:
Cytoskeleton Markers
Gene ID (Entrez):
2312
Target Species:
Human
Form:
Purified
Antigen: Filaggrin
Classification: Monoclonal
Concentration: 0.2 mg/mL
Dilution: Flow Cytometry 0.5 - 1 ug/million cells, Immunocytochemistry/Immunofluorescence 1 - 2 ug/ml, Immunohistochemistry-Paraffin 0.5 - 1.0 ug/ml
Gene Alias: ATOD2, epidermal filaggrin, filaggrin, Profilaggrin
Host Species: Mouse
Purification Method: Protein A or G purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: Filaggrin is an intermediate filament-associated protein that aggregates keratin intermediate filaments in mammalian epidermis. It is initially synthesized as a polyprotein precursor, profilaggrin (consisting of multiple filaggrin units of 324 aa each), which is localized in keratohyalin granules, and is subsequently proteolytically processed into individual functional filaggrin molecules. Active filaggrin is present at a level of the epidermis where keratinocytes are in transition between the live nucleated granular layer and the anucleate cornified layer, suggesting that filaggrin aids in the terminal differentiation process by facilitating apoptotic machinery.
Content And Storage: Store at 4C.
Isotype: IgG1 κ
Applications: Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)
Clone: SPM181
Conjugate: Unconjugated
Formulation: 10mM PBS with 0.05% BSA with 0.05% Sodium Azide
Gene Symbols: FLG
Immunogen: Recombinant human Filaggrin protein
Quantity: 100 μg
Research Discipline: Cytoskeleton Markers
Gene ID (Entrez): 2312
Target Species: Human
Form: Purified
Antigen:
Filaggrin
Classification:
Monoclonal
Concentration:
0.2 mg/mL
Dilution:
Flow Cytometry 0.5 - 1 ug/million cells, Immunocytochemistry/Immunofluorescence 1 - 2 ug/ml, Immunohistochemistry-Paraffin 0.5 - 1.0 ug/ml
Gene Alias:
ATOD2, epidermal filaggrin, filaggrin, Profilaggrin
Host Species:
Mouse
Purification Method:
Protein A or G purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
Filaggrin is an intermediate filament-associated protein that aggregates keratin intermediate filaments in mammalian epidermis. It is initially synthesized as a polyprotein precursor, profilaggrin (consisting of multiple filaggrin units of 324 aa each), which is localized in keratohyalin granules, and is subsequently proteolytically processed into individual functional filaggrin molecules. Active filaggrin is present at a level of the epidermis where keratinocytes are in transition between the live nucleated granular layer and the anucleate cornified layer, suggesting that filaggrin aids in the terminal differentiation process by facilitating apoptotic machinery.
Content And Storage:
Store at 4C.
Isotype:
IgG1 κ
Applications:
Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)
Clone:
SPM181
Conjugate:
Unconjugated
Formulation:
10mM PBS with 0.05% BSA with 0.05% Sodium Azide
Gene Symbols:
FLG
Immunogen:
Recombinant human Filaggrin protein
Quantity:
100 μg
Research Discipline:
Cytoskeleton Markers
Gene ID (Entrez):
2312
Target Species:
Human
Form:
Purified
Antigen: Filaggrin
Classification: Monoclonal
Concentration: 0.2 mg/mL
Dilution: Flow Cytometry 0.5 - 1 ug/million cells, Immunocytochemistry/Immunofluorescence 1 - 2 ug/ml, Immunohistochemistry-Paraffin 0.5 - 1.0 ug/ml
Gene Alias: ATOD2, epidermal filaggrin, filaggrin, Profilaggrin
Host Species: Mouse
Purification Method: Protein A or G purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: Filaggrin is an intermediate filament-associated protein that aggregates keratin intermediate filaments in mammalian epidermis. It is initially synthesized as a polyprotein precursor, profilaggrin (consisting of multiple filaggrin units of 324 aa each), which is localized in keratohyalin granules, and is subsequently proteolytically processed into individual functional filaggrin molecules. Active filaggrin is present at a level of the epidermis where keratinocytes are in transition between the live nucleated granular layer and the anucleate cornified layer, suggesting that filaggrin aids in the terminal differentiation process by facilitating apoptotic machinery.
Content And Storage: Store at 4C.
Isotype: IgG1 κ
Applications: Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)
Clone: SPM181
Conjugate: Unconjugated
Formulation: 10mM PBS with 0.05% BSA with 0.05% Sodium Azide
Gene Symbols: FLG
Immunogen: Recombinant human Filaggrin protein
Quantity: 20 μg
Research Discipline: Cytoskeleton Markers
Gene ID (Entrez): 2312
Target Species: Human
Form: Purified
Antigen:
Filaggrin
Classification:
Monoclonal
Concentration:
0.2 mg/mL
Dilution:
Flow Cytometry 0.5 - 1 ug/million cells, Immunocytochemistry/Immunofluorescence 1 - 2 ug/ml, Immunohistochemistry-Paraffin 0.5 - 1.0 ug/ml
Gene Alias:
ATOD2, epidermal filaggrin, filaggrin, Profilaggrin
Host Species:
Mouse
Purification Method:
Protein A or G purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
Filaggrin is an intermediate filament-associated protein that aggregates keratin intermediate filaments in mammalian epidermis. It is initially synthesized as a polyprotein precursor, profilaggrin (consisting of multiple filaggrin units of 324 aa each), which is localized in keratohyalin granules, and is subsequently proteolytically processed into individual functional filaggrin molecules. Active filaggrin is present at a level of the epidermis where keratinocytes are in transition between the live nucleated granular layer and the anucleate cornified layer, suggesting that filaggrin aids in the terminal differentiation process by facilitating apoptotic machinery.
Content And Storage:
Store at 4C.
Isotype:
IgG1 κ
Applications:
Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)
Clone:
SPM181
Conjugate:
Unconjugated
Formulation:
10mM PBS with 0.05% BSA with 0.05% Sodium Azide
Gene Symbols:
FLG
Immunogen:
Recombinant human Filaggrin protein
Quantity:
20 μg
Research Discipline:
Cytoskeleton Markers
Gene ID (Entrez):
2312
Target Species:
Human
Form:
Purified
Antigen: Filaggrin
Classification: Monoclonal
Concentration: 0.2 mg/mL
Dilution: Flow Cytometry 0.5 - 1 ug/million cells, Immunocytochemistry/Immunofluorescence 1 - 2 ug/ml, Immunohistochemistry-Paraffin 0.5 - 1.0 ug/ml
Gene Alias: ATOD2, epidermal filaggrin, filaggrin, Profilaggrin
Host Species: Mouse
Purification Method: Protein A or G purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: Filaggrin is an intermediate filament-associated protein that aggregates keratin intermediate filaments in mammalian epidermis. It is initially synthesized as a polyprotein precursor, profilaggrin (consisting of multiple filaggrin units of 324 aa each), which is localized in keratohyalin granules, and is subsequently proteolytically processed into individual functional filaggrin molecules. Active filaggrin is present at a level of the epidermis where keratinocytes are in transition between the live nucleated granular layer and the anucleate cornified layer, suggesting that filaggrin aids in the terminal differentiation process by facilitating apoptotic machinery.
Content And Storage: Store at 4C.
Isotype: IgG1 κ
Applications: Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)
Clone: SPM181
Conjugate: Unconjugated
Formulation: 10mM PBS with 0.05% BSA with 0.05% Sodium Azide
Gene Symbols: FLG
Immunogen: Recombinant human Filaggrin protein
Quantity: 200 μg
Research Discipline: Cytoskeleton Markers
Gene ID (Entrez): 2312
Target Species: Human
Form: Purified
Antigen:
Filaggrin
Classification:
Monoclonal
Concentration:
0.2 mg/mL
Dilution:
Flow Cytometry 0.5 - 1 ug/million cells, Immunocytochemistry/Immunofluorescence 1 - 2 ug/ml, Immunohistochemistry-Paraffin 0.5 - 1.0 ug/ml
Gene Alias:
ATOD2, epidermal filaggrin, filaggrin, Profilaggrin
Host Species:
Mouse
Purification Method:
Protein A or G purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
Filaggrin is an intermediate filament-associated protein that aggregates keratin intermediate filaments in mammalian epidermis. It is initially synthesized as a polyprotein precursor, profilaggrin (consisting of multiple filaggrin units of 324 aa each), which is localized in keratohyalin granules, and is subsequently proteolytically processed into individual functional filaggrin molecules. Active filaggrin is present at a level of the epidermis where keratinocytes are in transition between the live nucleated granular layer and the anucleate cornified layer, suggesting that filaggrin aids in the terminal differentiation process by facilitating apoptotic machinery.
Content And Storage:
Store at 4C.
Isotype:
IgG1 κ
Applications:
Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)
Clone:
SPM181
Conjugate:
Unconjugated
Formulation:
10mM PBS with 0.05% BSA with 0.05% Sodium Azide
Gene Symbols:
FLG
Immunogen:
Recombinant human Filaggrin protein
Quantity:
200 μg
Research Discipline:
Cytoskeleton Markers
Gene ID (Entrez):
2312
Target Species:
Human
Form:
Purified