NB25324420
Filaggrin Antibody (SPM181), Novus Biologicals™
Manufacturer: Fischer Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | NB25324420-Each-of-1 | In Stock | ₹ 22,930.08 |
NB25324420 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 22,930.08
GST (18%): ₹ 4,127.414
Total Price: ₹ 27,057.494
Antigen
Filaggrin
Classification
Monoclonal
Concentration
0.2 mg/mL
Dilution
Flow Cytometry 0.5 - 1 ug/million cells, Immunocytochemistry/Immunofluorescence 1 - 2 ug/ml, Immunohistochemistry-Paraffin 0.5 - 1.0 ug/ml
Gene Alias
ATOD2, epidermal filaggrin, filaggrin, Profilaggrin
Host Species
Mouse
Purification Method
Protein A or G purified
Regulatory Status
RUO
Primary or Secondary
Primary
Test Specificity
Filaggrin is an intermediate filament-associated protein that aggregates keratin intermediate filaments in mammalian epidermis. It is initially synthesized as a polyprotein precursor, profilaggrin (consisting of multiple filaggrin units of 324 aa each), which is localized in keratohyalin granules, and is subsequently proteolytically processed into individual functional filaggrin molecules. Active filaggrin is present at a level of the epidermis where keratinocytes are in transition between the live nucleated granular layer and the anucleate cornified layer, suggesting that filaggrin aids in the terminal differentiation process by facilitating apoptotic machinery.
Content And Storage
Store at 4C.
Isotype
IgG1 κ
Applications
Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)
Clone
SPM181
Conjugate
Unconjugated
Formulation
10mM PBS with 0.05% BSA with 0.05% Sodium Azide
Gene Symbols
FLG
Immunogen
Recombinant human Filaggrin protein
Quantity
20 μg
Research Discipline
Cytoskeleton Markers
Gene ID (Entrez)
2312
Target Species
Human
Form
Purified
Related Products
Description
- Filaggrin Monoclonal specifically detects Filaggrin in Human samples
- It is validated for Immunohistochemistry, Immunohistochemistry-Paraffin.
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Show Difference
Antigen: Filaggrin
Classification: Monoclonal
Concentration: 0.2 mg/mL
Dilution: Flow Cytometry 0.5 - 1 ug/million cells, Immunocytochemistry/Immunofluorescence 1 - 2 ug/ml, Immunohistochemistry-Paraffin 0.5 - 1.0 ug/ml
Gene Alias: ATOD2, epidermal filaggrin, filaggrin, Profilaggrin
Host Species: Mouse
Purification Method: Protein A or G purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: Filaggrin is an intermediate filament-associated protein that aggregates keratin intermediate filaments in mammalian epidermis. It is initially synthesized as a polyprotein precursor, profilaggrin (consisting of multiple filaggrin units of 324 aa each), which is localized in keratohyalin granules, and is subsequently proteolytically processed into individual functional filaggrin molecules. Active filaggrin is present at a level of the epidermis where keratinocytes are in transition between the live nucleated granular layer and the anucleate cornified layer, suggesting that filaggrin aids in the terminal differentiation process by facilitating apoptotic machinery.
Content And Storage: Store at 4C.
Isotype: IgG1 κ
Applications: Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)
Clone: SPM181
Conjugate: Unconjugated
Formulation: 10mM PBS with 0.05% BSA with 0.05% Sodium Azide
Gene Symbols: FLG
Immunogen: Recombinant human Filaggrin protein
Quantity: 20 μg
Research Discipline: Cytoskeleton Markers
Gene ID (Entrez): 2312
Target Species: Human
Form: Purified
Antigen:
Filaggrin
Classification:
Monoclonal
Concentration:
0.2 mg/mL
Dilution:
Flow Cytometry 0.5 - 1 ug/million cells, Immunocytochemistry/Immunofluorescence 1 - 2 ug/ml, Immunohistochemistry-Paraffin 0.5 - 1.0 ug/ml
Gene Alias:
ATOD2, epidermal filaggrin, filaggrin, Profilaggrin
Host Species:
Mouse
Purification Method:
Protein A or G purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
Filaggrin is an intermediate filament-associated protein that aggregates keratin intermediate filaments in mammalian epidermis. It is initially synthesized as a polyprotein precursor, profilaggrin (consisting of multiple filaggrin units of 324 aa each), which is localized in keratohyalin granules, and is subsequently proteolytically processed into individual functional filaggrin molecules. Active filaggrin is present at a level of the epidermis where keratinocytes are in transition between the live nucleated granular layer and the anucleate cornified layer, suggesting that filaggrin aids in the terminal differentiation process by facilitating apoptotic machinery.
Content And Storage:
Store at 4C.
Isotype:
IgG1 κ
Applications:
Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)
Clone:
SPM181
Conjugate:
Unconjugated
Formulation:
10mM PBS with 0.05% BSA with 0.05% Sodium Azide
Gene Symbols:
FLG
Immunogen:
Recombinant human Filaggrin protein
Quantity:
20 μg
Research Discipline:
Cytoskeleton Markers
Gene ID (Entrez):
2312
Target Species:
Human
Form:
Purified
Antigen: Filaggrin
Classification: Monoclonal
Concentration: 0.2 mg/mL
Dilution: Flow Cytometry 0.5 - 1 ug/million cells, Immunocytochemistry/Immunofluorescence 1 - 2 ug/ml, Immunohistochemistry-Paraffin 0.5 - 1.0 ug/ml
Gene Alias: ATOD2, epidermal filaggrin, filaggrin, Profilaggrin
Host Species: Mouse
Purification Method: Protein A or G purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: Filaggrin is an intermediate filament-associated protein that aggregates keratin intermediate filaments in mammalian epidermis. It is initially synthesized as a polyprotein precursor, profilaggrin (consisting of multiple filaggrin units of 324 aa each), which is localized in keratohyalin granules, and is subsequently proteolytically processed into individual functional filaggrin molecules. Active filaggrin is present at a level of the epidermis where keratinocytes are in transition between the live nucleated granular layer and the anucleate cornified layer, suggesting that filaggrin aids in the terminal differentiation process by facilitating apoptotic machinery.
Content And Storage: Store at 4C.
Isotype: IgG1 κ
Applications: Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)
Clone: SPM181
Conjugate: Unconjugated
Formulation: 10mM PBS with 0.05% BSA with 0.05% Sodium Azide
Gene Symbols: FLG
Immunogen: Recombinant human Filaggrin protein
Quantity: 200 μg
Research Discipline: Cytoskeleton Markers
Gene ID (Entrez): 2312
Target Species: Human
Form: Purified
Antigen:
Filaggrin
Classification:
Monoclonal
Concentration:
0.2 mg/mL
Dilution:
Flow Cytometry 0.5 - 1 ug/million cells, Immunocytochemistry/Immunofluorescence 1 - 2 ug/ml, Immunohistochemistry-Paraffin 0.5 - 1.0 ug/ml
Gene Alias:
ATOD2, epidermal filaggrin, filaggrin, Profilaggrin
Host Species:
Mouse
Purification Method:
Protein A or G purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
Filaggrin is an intermediate filament-associated protein that aggregates keratin intermediate filaments in mammalian epidermis. It is initially synthesized as a polyprotein precursor, profilaggrin (consisting of multiple filaggrin units of 324 aa each), which is localized in keratohyalin granules, and is subsequently proteolytically processed into individual functional filaggrin molecules. Active filaggrin is present at a level of the epidermis where keratinocytes are in transition between the live nucleated granular layer and the anucleate cornified layer, suggesting that filaggrin aids in the terminal differentiation process by facilitating apoptotic machinery.
Content And Storage:
Store at 4C.
Isotype:
IgG1 κ
Applications:
Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)
Clone:
SPM181
Conjugate:
Unconjugated
Formulation:
10mM PBS with 0.05% BSA with 0.05% Sodium Azide
Gene Symbols:
FLG
Immunogen:
Recombinant human Filaggrin protein
Quantity:
200 μg
Research Discipline:
Cytoskeleton Markers
Gene ID (Entrez):
2312
Target Species:
Human
Form:
Purified
Antigen: RPRD1B
Classification: Monoclonal
Concentration: __
Dilution: Immunohistochemistry, Immunohistochemistry-Paraffin
Gene Alias: Cell cycle-related and expression-elevated protein in tumor, cell-cycle related and expression-elevated protein in tumor, chromosome 20 open reading frame 77, CREPTC20orf77, dJ1057B20.2, DKFZp434P0735, FLJ44520, NET60, regulation of nuclear pre-mRNA domain containing 1B, regulation of nuclear pre-mRNA domain-containing protein 1B
Host Species: Mouse
Purification Method: Protein A purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: __
Content And Storage: Store at 4°C in the dark.
Isotype: IgG
Applications: Immunohistochemistry, Immunohistochemistry (Paraffin)
Clone: 08
Conjugate: DyLight 755
Formulation: 50mM Sodium Borate
Gene Symbols: __
Immunogen: This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human RPRD1B (AAH33629.1; Met1-Asp326).
Quantity: 0.1 mL
Research Discipline: __
Gene ID (Entrez): 58490
Target Species: Human
Form: Purified
Antigen:
RPRD1B
Classification:
Monoclonal
Concentration:
__
Dilution:
Immunohistochemistry, Immunohistochemistry-Paraffin
Gene Alias:
Cell cycle-related and expression-elevated protein in tumor, cell-cycle related and expression-elevated protein in tumor, chromosome 20 open reading frame 77, CREPTC20orf77, dJ1057B20.2, DKFZp434P0735, FLJ44520, NET60, regulation of nuclear pre-mRNA domain containing 1B, regulation of nuclear pre-mRNA domain-containing protein 1B
Host Species:
Mouse
Purification Method:
Protein A purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
__
Content And Storage:
Store at 4°C in the dark.
Isotype:
IgG
Applications:
Immunohistochemistry, Immunohistochemistry (Paraffin)
Clone:
08
Conjugate:
DyLight 755
Formulation:
50mM Sodium Borate
Gene Symbols:
__
Immunogen:
This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human RPRD1B (AAH33629.1; Met1-Asp326).
Quantity:
0.1 mL
Research Discipline:
__
Gene ID (Entrez):
58490
Target Species:
Human
Form:
Purified
Antigen: Elastase
Classification: Monoclonal
Concentration: 0.2 mg/mL
Dilution: Flow Cytometry 0.5 - 1 ug/million cells, ELISA 2 - 4 ug/ml, Immunocytochemistry/Immunofluorescence 0.5 - 1 ug/ml, Immunohistochemistry-Paraffin 0.5 - 1.0 ug/ml
Gene Alias: CBPP, cholesterol-binding pancreatic protease, chymotrypsin-like elastase family member 3B, chymotrypsin-like elastase family, member 3B, E1, EC 3.4.21, EC 3.4.21.70, EL-1, ELA3B, elastase 1, elastase 3B, pancreatic, Elastase IIIB, elastase-3B, fecal elastase 1, pancreatic elastase 1, pancreatic endopeptidase E, Protease E, proteinase E
Host Species: Mouse
Purification Method: Protein A or G purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: __
Content And Storage: Store at 4C.
Isotype: IgG1
Applications: Flow Cytometry, ELISA, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)
Clone: CELA3B/1257
Conjugate: Unconjugated
Formulation: 10mM PBS with 0.05% BSA with 0.05% Sodium Azide
Gene Symbols: CELA3B
Immunogen: Recombinant human CELA3B protein fragment (aa82-238) (exact sequence is proprietary)
Quantity: 100 μg
Research Discipline: Cancer, Neuroscience
Gene ID (Entrez): 23436
Target Species: Human, Mouse, Rat
Form: Purified
Antigen:
Elastase
Classification:
Monoclonal
Concentration:
0.2 mg/mL
Dilution:
Flow Cytometry 0.5 - 1 ug/million cells, ELISA 2 - 4 ug/ml, Immunocytochemistry/Immunofluorescence 0.5 - 1 ug/ml, Immunohistochemistry-Paraffin 0.5 - 1.0 ug/ml
Gene Alias:
CBPP, cholesterol-binding pancreatic protease, chymotrypsin-like elastase family member 3B, chymotrypsin-like elastase family, member 3B, E1, EC 3.4.21, EC 3.4.21.70, EL-1, ELA3B, elastase 1, elastase 3B, pancreatic, Elastase IIIB, elastase-3B, fecal elastase 1, pancreatic elastase 1, pancreatic endopeptidase E, Protease E, proteinase E
Host Species:
Mouse
Purification Method:
Protein A or G purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
__
Content And Storage:
Store at 4C.
Isotype:
IgG1
Applications:
Flow Cytometry, ELISA, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)
Clone:
CELA3B/1257
Conjugate:
Unconjugated
Formulation:
10mM PBS with 0.05% BSA with 0.05% Sodium Azide
Gene Symbols:
CELA3B
Immunogen:
Recombinant human CELA3B protein fragment (aa82-238) (exact sequence is proprietary)
Quantity:
100 μg
Research Discipline:
Cancer, Neuroscience
Gene ID (Entrez):
23436
Target Species:
Human, Mouse, Rat
Form:
Purified