NBP233110W

Chorionic Gonadotropin beta Chain (hCG beta) Antibody (HCGb/54), Alexa Fluor™ 405, Novus Biologicals™

Manufacturer: Novus Biologicals

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Pack Size SKU Availability Price
Each of 1 NBP233110W-Each-of-1 In Stock ₹ 55,271.76

NBP233110W - Each of 1

₹ 55,271.76

In Stock

Quantity

1

Base Price: ₹ 55,271.76

GST (18%): ₹ 9,948.917

Total Price: ₹ 65,220.677

Antigen

Chorionic Gonadotropin beta Chain (HCG beta)

Classification

Monoclonal

Conjugate

Alexa Fluor 405

Gene Alias

CGB3choriogonadotropin subunit beta, CGB5, CGB7, CGB8, CG-beta, Chorionic gonadotrophin chain beta, chorionic gonadotropin beta 3 subunit, chorionic gonadotropin beta chain, chorionic gonadotropin beta subunit, chorionic gonadotropin, beta polypeptide, hCGB

Host Species

Mouse

Molecular Weight of Antigen

22 kDa

Quantity

0.1 mL

Research Discipline

Cancer

Gene ID (Entrez)

1082

Target Species

Human

Form

Purified

Applications

Western Blot, ELISA, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen)

Clone

HCGb/54

Dilution

Western Blot, ELISA, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen

Gene Symbols

CGB3

Immunogen

Recombinant full-length Chorionic Gonadotropin beta Chain (hCG beta) protein (Uniprot: P01233)

Purification Method

Protein A or G purified

Regulatory Status

RUO

Primary or Secondary

Primary

Test Specificity

This monoclonal antibody reacts with a protein of 22kDa, identified as beta sub-unit of HCG. It does not cross react with the alpha sub-unit. HCG is a glycoprotein, which is secreted in large quantities by normal trophoblasts. It is present only in trace amounts in non-pregnant urine and sera but rises sharply during pregnancy. HCG is composed of two non-identical, non-covalently linked polypeptide chains designated as the subunit is identical to that of thyroid stimulating hormone (TSH) follicle stimulating hormone (FSH), and luteinizing hormone (LH). hCG monoclonal antibody detects cells and tumors of trophoblastic origin such as choriocarcinoma. Large cell carcinoma and adenocarcinoma of the lung demonstrate anti-hCG positivity in 90% and 60% of cases respectively. 20% of lung squamous cell carcinomas are positive. hCG expression by non-trophoblastic tumors may indicate aggressive behavior.

Content And Storage

Store at 4C in the dark.

Isotype

IgG1 κ

Description

  • Chorionic Gonadotropin beta Chain (hCG beta) Monoclonal specifically detects Chorionic Gonadotropin beta Chain (hCG beta) in Human samples
  • It is validated for Immunohistochemistry, Immunohistochemistry-Paraffin.

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Img

Novus Biologicals

NBP233110W

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Antigen:
Chorionic Gonadotropin beta Chain (HCG beta)

Classification:
Monoclonal

Conjugate:
Alexa Fluor 405

Gene Alias:
CGB3choriogonadotropin subunit beta, CGB5, CGB7, CGB8, CG-beta, Chorionic gonadotrophin chain beta, chorionic gonadotropin beta 3 subunit, chorionic gonadotropin beta chain, chorionic gonadotropin beta subunit, chorionic gonadotropin, beta polypeptide, hCGB

Host Species:
Mouse

Molecular Weight of Antigen:
22 kDa

Quantity:
0.1 mL

Research Discipline:
Cancer

Gene ID (Entrez):
1082

Target Species:
Human

Form:
Purified

Applications:
Western Blot, ELISA, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen)

Clone:
HCGb/54

Dilution:
Western Blot, ELISA, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen

Gene Symbols:
CGB3

Immunogen:
Recombinant full-length Chorionic Gonadotropin beta Chain (hCG beta) protein (Uniprot: P01233)

Purification Method:
Protein A or G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
This monoclonal antibody reacts with a protein of 22kDa, identified as beta sub-unit of HCG. It does not cross react with the alpha sub-unit. HCG is a glycoprotein, which is secreted in large quantities by normal trophoblasts. It is present only in trace amounts in non-pregnant urine and sera but rises sharply during pregnancy. HCG is composed of two non-identical, non-covalently linked polypeptide chains designated as the subunit is identical to that of thyroid stimulating hormone (TSH) follicle stimulating hormone (FSH), and luteinizing hormone (LH). hCG monoclonal antibody detects cells and tumors of trophoblastic origin such as choriocarcinoma. Large cell carcinoma and adenocarcinoma of the lung demonstrate anti-hCG positivity in 90% and 60% of cases respectively. 20% of lung squamous cell carcinomas are positive. hCG expression by non-trophoblastic tumors may indicate aggressive behavior.

Content And Storage:
Store at 4C in the dark.

Isotype:
IgG1 κ

Img

Novus Biologicals

NBP233126

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Antigen:
Uroplakin III

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene Alias:
MGC119178, UP3a, UPIII, UPIIIA, UPK3, UPK3A, uroplakin 3, uroplakin 3A, Uroplakin III, uroplakin3a, uroplakin-3a

Host Species:
Rabbit

Molecular Weight of Antigen:
30 kDa

Quantity:
0.1 mg

Research Discipline:
Cancer

Gene ID (Entrez):
7380

Target Species:
Human

Form:
Purified

Applications:
Western Blot, Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunoprecipitation, CyTOF

Clone:
__

Dilution:
Western Blot 0.5-1ug/ml, Flow Cytometry 0.5-1ug/million cells, Immunocytochemistry/Immunofluorescence 1-2ug/ml, Immunoprecipitation 0.5-1ug/500ug protein lysate, CyTOF-ready

Gene Symbols:
UPK3A

Immunogen:
A synthetic peptide, aa260-279 (GASESSYTSVNRGPPLDRAE) of human Uroplakin III (Uniprot: O75631)

Purification Method:
Protein A purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
Uroplakin-3A (UPK3A) is a component of the asymmetric unit membrane (AUM). It is a highly specialized bio-membrane made by terminally differentiated urothelial cells. The protein may play an important role in AUM-cytoskeleton interaction in terminally differentiated urothelial cells. UPK3A also contributes to the formation of urothelial glycocalyx, which may play an important role in preventing bacterial adherence through FimH bacterial protein binding leading to bladder infection. UPK3A has been shown as a helpful marker for the detection of bladder cancer.

Content And Storage:
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Isotype:
IgG

Img

Novus Biologicals

NBP233128C

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Antigen:
TAG-72

Classification:
Monoclonal

Conjugate:
DyLight 650

Gene Alias:
CA 72-4, Protein TAG-72, tag 72, tag-72 Protein TAG-72

Host Species:
Mouse

Molecular Weight of Antigen:
220 kDa

Quantity:
0.1 mL

Research Discipline:
__

Gene ID (Entrez):
182875

Target Species:
Human, Rat, Bovine, Canine

Form:
Purified

Applications:
Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen)

Clone:
CC49

Dilution:
Western Blot 1:100-1:2000, Flow Cytometry 1:10-1:1000, ELISA 1-5 μg/mL for coating, Immunohistochemistry, Immunocytochemistry/Immunofluorescence 1:10-1:500, Immunohistochemistry-Paraffin 1:10-1:500, Immunohistochemistry-Frozen 1:10-1:500

Gene Symbols:
__

Immunogen:
Purified TAG-72 protein

Purification Method:
Protein A or G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
Recognizes an oncofetal antigen of 220kDa, identified as a tumor-associated glycoprotein (TAG-72) with properties of a mucin. This monoclonal antibody defines the mucin-carried sialylated-Tn epitope. TAG-72 is usually expressed by adenocarcinomas, but is negative in mesotheliomas. Studies have reported that this antibody has 80% sensitivity and 93% specificity for pulmonary adenocarcinoma. Therefore, TAG-72 is a useful marker to distinguish between mesothelioma and adenocarcinoma. However, false positive reactions can occur so results must be interpreted with the utmost caution. This antibody may be useful in the differentiation of non-small cell carcinomas from small cell carcinomas of the lung. The combined use of anti-TAG-72 and anti-GCDFP-15 is valuable in the diagnosis of apocrine carcinoma.

Content And Storage:
Store at 4C in the dark.

Isotype:
IgG1 κ

Img

Novus Biologicals

NBP233128FR

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Antigen:
TAG-72

Classification:
Monoclonal

Conjugate:
DyLight 680

Gene Alias:
CA 72-4, Protein TAG-72, tag 72, tag-72 Protein TAG-72

Host Species:
Mouse

Molecular Weight of Antigen:
220 kDa

Quantity:
0.1 mL

Research Discipline:
__

Gene ID (Entrez):
182875

Target Species:
Human, Rat, Bovine, Canine

Form:
Purified

Applications:
Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen)

Clone:
CC49

Dilution:
Western Blot 1:100-1:2000, Flow Cytometry 1:10-1:1000, ELISA 1-5 μg/mL for coating, Immunohistochemistry, Immunocytochemistry/Immunofluorescence 1:10-1:500, Immunohistochemistry-Paraffin 1:10-1:500, Immunohistochemistry-Frozen 1:10-1:500

Gene Symbols:
__

Immunogen:
Purified TAG-72 protein

Purification Method:
Protein A or G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
Recognizes an oncofetal antigen of 220kDa, identified as a tumor-associated glycoprotein (TAG-72) with properties of a mucin. This monoclonal antibody defines the mucin-carried sialylated-Tn epitope. TAG-72 is usually expressed by adenocarcinomas, but is negative in mesotheliomas. Studies have reported that this antibody has 80% sensitivity and 93% specificity for pulmonary adenocarcinoma. Therefore, TAG-72 is a useful marker to distinguish between mesothelioma and adenocarcinoma. However, false positive reactions can occur so results must be interpreted with the utmost caution. This antibody may be useful in the differentiation of non-small cell carcinomas from small cell carcinomas of the lung. The combined use of anti-TAG-72 and anti-GCDFP-15 is valuable in the diagnosis of apocrine carcinoma.

Content And Storage:
Store at 4C in the dark.

Isotype:
IgG1 κ