NBP233128Y

TAG-72 Antibody (CC49), Alexa Fluor™ 647, Novus Biologicals™

Manufacturer: Novus Biologicals

Select a Size

Pack Size SKU Availability Price
Each of 1 NBP233128Y-Each-of-1 In Stock ₹ 55,271.76

NBP233128Y - Each of 1

₹ 55,271.76

In Stock

Quantity

1

Base Price: ₹ 55,271.76

GST (18%): ₹ 9,948.917

Total Price: ₹ 65,220.677

Antigen

TAG-72

Classification

Monoclonal

Conjugate

Alexa Fluor 647

Gene Alias

CA 72-4, Protein TAG-72, tag 72, tag-72 Protein TAG-72

Immunogen

Purified TAG-72 protein

Purification Method

Protein A or G purified

Regulatory Status

RUO

Gene ID (Entrez)

182875

Target Species

Human, Rat, Bovine, Canine

Form

Purified

Applications

Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen)

Clone

CC49

Dilution

Western Blot 1:100-1:2000, Flow Cytometry 1:10-1:1000, ELISA 1-5 μg/mL for coating, Immunohistochemistry, Immunocytochemistry/Immunofluorescence 1:10-1:500, Immunohistochemistry-Paraffin 1:10-1:500, Immunohistochemistry-Frozen 1:10-1:500

Host Species

Mouse

Molecular Weight of Antigen

220 kDa

Quantity

0.1 mL

Primary or Secondary

Primary

Test Specificity

Recognizes an oncofetal antigen of 220kDa, identified as a tumor-associated glycoprotein (TAG-72) with properties of a mucin. This monoclonal antibody defines the mucin-carried sialylated-Tn epitope. TAG-72 is usually expressed by adenocarcinomas, but is negative in mesotheliomas. Studies have reported that this antibody has 80% sensitivity and 93% specificity for pulmonary adenocarcinoma. Therefore, TAG-72 is a useful marker to distinguish between mesothelioma and adenocarcinoma. However, false positive reactions can occur so results must be interpreted with the utmost caution. This antibody may be useful in the differentiation of non-small cell carcinomas from small cell carcinomas of the lung. The combined use of anti-TAG-72 and anti-GCDFP-15 is valuable in the diagnosis of apocrine carcinoma.

Content And Storage

Store at 4C in the dark.

Isotype

IgG1 κ

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Description

  • TAG-72 Monoclonal specifically detects TAG-72 in Human, Rat, Bovine, Canine samples
  • It is validated for Immunohistochemistry, Immunohistochemistry-Paraffin.

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Novus Biologicals

NBP233128Y

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Antigen:
TAG-72

Classification:
Monoclonal

Conjugate:
Alexa Fluor 647

Gene Alias:
CA 72-4, Protein TAG-72, tag 72, tag-72 Protein TAG-72

Immunogen:
Purified TAG-72 protein

Purification Method:
Protein A or G purified

Regulatory Status:
RUO

Gene ID (Entrez):
182875

Target Species:
Human, Rat, Bovine, Canine

Form:
Purified

Applications:
Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen)

Clone:
CC49

Dilution:
Western Blot 1:100-1:2000, Flow Cytometry 1:10-1:1000, ELISA 1-5 μg/mL for coating, Immunohistochemistry, Immunocytochemistry/Immunofluorescence 1:10-1:500, Immunohistochemistry-Paraffin 1:10-1:500, Immunohistochemistry-Frozen 1:10-1:500

Host Species:
Mouse

Molecular Weight of Antigen:
220 kDa

Quantity:
0.1 mL

Primary or Secondary:
Primary

Test Specificity:
Recognizes an oncofetal antigen of 220kDa, identified as a tumor-associated glycoprotein (TAG-72) with properties of a mucin. This monoclonal antibody defines the mucin-carried sialylated-Tn epitope. TAG-72 is usually expressed by adenocarcinomas, but is negative in mesotheliomas. Studies have reported that this antibody has 80% sensitivity and 93% specificity for pulmonary adenocarcinoma. Therefore, TAG-72 is a useful marker to distinguish between mesothelioma and adenocarcinoma. However, false positive reactions can occur so results must be interpreted with the utmost caution. This antibody may be useful in the differentiation of non-small cell carcinomas from small cell carcinomas of the lung. The combined use of anti-TAG-72 and anti-GCDFP-15 is valuable in the diagnosis of apocrine carcinoma.

Content And Storage:
Store at 4C in the dark.

Isotype:
IgG1 κ

Img

Novus Biologicals

NBP233128Z

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Antigen:
TAG-72

Classification:
Monoclonal

Conjugate:
Alexa Fluor 700

Gene Alias:
CA 72-4, Protein TAG-72, tag 72, tag-72 Protein TAG-72

Immunogen:
Purified TAG-72 protein

Purification Method:
Protein A or G purified

Regulatory Status:
RUO

Gene ID (Entrez):
182875

Target Species:
Human, Rat, Bovine, Canine

Form:
Purified

Applications:
Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen)

Clone:
CC49

Dilution:
Western Blot 1:100-1:2000, Flow Cytometry 1:10-1:1000, ELISA 1-5 μg/mL for coating, Immunohistochemistry, Immunocytochemistry/Immunofluorescence 1:10-1:500, Immunohistochemistry-Paraffin 1:10-1:500, Immunohistochemistry-Frozen 1:10-1:500

Host Species:
Mouse

Molecular Weight of Antigen:
220 kDa

Quantity:
0.1 mL

Primary or Secondary:
Primary

Test Specificity:
Recognizes an oncofetal antigen of 220kDa, identified as a tumor-associated glycoprotein (TAG-72) with properties of a mucin. This monoclonal antibody defines the mucin-carried sialylated-Tn epitope. TAG-72 is usually expressed by adenocarcinomas, but is negative in mesotheliomas. Studies have reported that this antibody has 80% sensitivity and 93% specificity for pulmonary adenocarcinoma. Therefore, TAG-72 is a useful marker to distinguish between mesothelioma and adenocarcinoma. However, false positive reactions can occur so results must be interpreted with the utmost caution. This antibody may be useful in the differentiation of non-small cell carcinomas from small cell carcinomas of the lung. The combined use of anti-TAG-72 and anti-GCDFP-15 is valuable in the diagnosis of apocrine carcinoma.

Content And Storage:
Store at 4C in the dark.

Isotype:
IgG1 κ

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NBP233130X

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Antigen:
UCH-L1/PGP9.5

Classification:
Monoclonal

Conjugate:
Alexa Fluor 488

Gene Alias:
EC 3.4.19.12, EC 6.-, Neuron cytoplasmic protein 9.5, PARK5, PGP 9.5, PGP9.5, PGP9.5Uch-L1, PGP95, ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase), ubiquitin carboxyl-terminal hydrolase isozyme L1, ubiquitin C-terminal hydrolase, Ubiquitin thioesterase L1, UCHL1, UCH-L1

Immunogen:
UCH-L1/PGP9.5 protein from brain (Uniprot: P09936)

Purification Method:
Protein G purified

Regulatory Status:
RUO

Gene ID (Entrez):
7345

Target Species:
Human, Mouse, Rat, Porcine, Bovine

Form:
Purified

Applications:
Western Blot, Flow Cytometry, ELISA, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)

Clone:
31A3

Dilution:
Western Blot, Flow Cytometry, ELISA, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin

Host Species:
Mouse

Molecular Weight of Antigen:
25 kDa

Quantity:
0.1 mL

Primary or Secondary:
Primary

Test Specificity:
This MAb reacts with a protein of 20-30kDa, identified as PGP9.5, also known as ubiquitin carboxyl-terminal hydrolase-1 (UchL1). Initially, PGP9.5 expression in normal tissues was reported in neurons and neuroendocrine cells but later it was found in distal renal tubular epithelium, spermatogonia, Leydig cells, oocytes, melanocytes, prostatic secretory epithelium, ejaculatory duct cells, epididymis, mammary epithelial cells, Merkel cells, and dermal fibroblasts. Furthermore, immunostaining for PGP9.5 has been shown in a wide variety of mesenchymal neoplasms as well. A mutation in PGP9.5 gene is believed to cause a form of Parkinson's disease.

Content And Storage:
Store at 4C in the dark.

Isotype:
IgG1 κ

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NBP233132B

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Antigen:
NCAM-1/CD56

Classification:
Monoclonal

Conjugate:
Biotin

Gene Alias:
CD56, CD56 NCAM-1, CD56 antigen, MSK39, N-CAM-1, NCAM-1, NCAMantigen recognized by monoclonal 5.1H11, neural cell adhesion molecule 1, neural cell adhesion molecule, NCAM

Immunogen:
Membrane preparation of a small cell lung carcinoma.

Purification Method:
Protein A or G purified

Regulatory Status:
RUO

Gene ID (Entrez):
4684

Target Species:
Human, Rat, Zebrafish

Form:
Purified

Applications:
Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen)

Clone:
123C3.D5

Dilution:
Western Blot 1:100-1:2000, Flow Cytometry 1:10-1:1000, ELISA 1-5 μg/mL for coating, Immunohistochemistry, Immunocytochemistry/Immunofluorescence 1:10-1:500, Immunohistochemistry-Paraffin 1:10-1:500, Immunohistochemistry-Frozen 1:10-1:500

Host Species:
Mouse

Molecular Weight of Antigen:
__

Quantity:
0.1 mL

Primary or Secondary:
Primary

Test Specificity:
This monoclonal antibody reacts with an extracellular domain (close to transmembrane) of CD56/NCAM. Three isoforms of neural cell adhesion molecule (NCAM) are produced by differential splicing of the RNA transcript from a single gene. The 135kDa isoform is the basic molecule, which is glycosylated or sialylated to produce the mature species. Anti-CD56 recognizes two proteins of the neural cell adhesion molecule, the basic molecule expressed on most neuroectodermally derived tissues and neoplasms (e.g. retinoblastoma, medulloblastomas, astrocytomas, neuroblastomas, and small cell carcinomas). It is also expressed on some mesodermally derived tumors (rhabdomyosarcoma). Anti-CD56 plays an important role in the diagnosis of nodal and nasal NK/T-cell lymphomas.

Content And Storage:
Store at 4C in the dark.

Isotype:
IgG1 κ