Manufacturer: Fischer Scientific
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Caldesmon/CALD1
Monoclonal
0.2mg/mL
Flow Cytometry 0.5 - 1 ug/million cells in 0.1 ml, Immunohistochemistry-Paraffin 0.25 - 0.5 ug/ml, Immunofluorescence 1 - 2 ug/ml
Q05682
CALD1
Crude human uterus extract
Protein A or G purified
RUO
Primary
Recognizes a protein of 150kDa, which is identified as the high molecular weight variant of Caldesmon. Two closely related variants of human caldesmon have been identified which are different in their electrophoretic mobility and cellular distribution. The h-caldesmon variant (120-150kDa) is predominantly expressed in smooth muscle whereas l-caldesmon (70-80kDa) is found in non- muscle tissue and cells. Neither of the two variants has been detected in skeletal muscle. This MAb recognizes only the 150kDa variant (h-caldesmon) in Western blots of human aortic media extracts and is unreactive with fibroblast extracts from cultivated human foreskin. Caldesmon is a developmentally regulated protein involved in smooth muscle and non-muscle contraction.
Store at 4C.
IgG1 κ
Flow Cytometry, Immunohistochemistry (Paraffin), Immunofluorescence
SPM168
Unconjugated
10mM PBS and 0.05% BSA with 0.05% Sodium Azide
CAD, caldesmon, caldesmon 1, CDMH-CAD, HCAD, LCAD, L-CAD, MGC21352, NAG22
Mouse
150 kDa
0.2 mg
Cytoskeleton Markers
800
Human
Purified