NBP24444802
Endorepellin/Perlecan/Heparan Sulfate Proteoglycan Antibody (A7L6), Novus Biologicals™
Manufacturer: Fischer Scientific
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Antigen
Endorepellin/Perlecan/Heparan Sulfate Proteoglycan
Classification
Monoclonal
Concentration
0.2mg/mL
Dilution
Flow Cytometry 0.5 - 1 ug/million cells in 0.1 ml, Immunohistochemistry-Paraffin 1 - 2 ug/ml, SDS-Page, Immunofluorescence 0.5 - 1.0 ug/ml
Gene Accession No.
P98160
Gene Symbols
HSPG2
Immunogen
Murine EHS laminin preparation
Quantity
0.2 mg
Primary or Secondary
Primary
Test Specificity
This MAb specifically precipitates heterogeneous material of high MW, identified as perlecan, a major heparan-sulfate proteoglycan (HSPG) within all basement membranes and cell surfaces. It does not cross-react with laminin, fibronectin, or dermatran sulfate proteoglycan. Because of perlecan s strategic location and ability to store and protect growth factors, it has been strongly implicated in the control of tumor cell growth and metastatic behavior. Perlecan possesses angiogenic and growth-promoting attributes primarily by acting as a co-receptor for basic fibroblast growth factor (FGF-2). Suppression of perlecan causes substantial inhibition of neoplastic growth and neovascularization. Thus, perlecan is a potent inducer of neoplasm growth and angiogenesis in vivo and therapeutic interventions targeting this key modulator of tumor progression may improve neoplastic treatment.
Content And Storage
Store at 4C.
Isotype
IgG2a κ
Applications
Flow Cytometry, Immunohistochemistry (Paraffin), SDS-Page, Immunofluorescence
Clone
A7L6
Conjugate
Unconjugated
Formulation
10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Gene Alias
basement membrane-specific heparan sulfate proteoglycan core protein, endorepellin (domain V region), heparan sulfate proteoglycan 2, HSPG, perlecan, perlecan proteoglycan, PLCSchwartz-Jampel syndrome 1 (chondrodystrophic myotonia), PRCAN, SJA, SJS, SJS1
Host Species
Rat
Purification Method
Protein A or G purified
Regulatory Status
RUO
Gene ID (Entrez)
3339
Target Species
Human, Mouse, Porcine, Fish, Monkey
Form
Purified
Description
- Ensure accurate, reproducible results in Flow Cytometry, Immunohistochemistry (Paraffin), Immunofluorescence Endorepellin/Perlecan/Heparan Sulfate Proteoglycan Monoclonal specifically detects Endorepellin/Perlecan/Heparan Sulfate Proteoglycan in Human, Mouse, Porcine, Bovine, Fish, Monkey samples
- It is validated for Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen, Immunofluorescence.
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Antigen: Endorepellin/Perlecan/Heparan Sulfate Proteoglycan
Classification: Monoclonal
Concentration: 0.2mg/mL
Dilution: Flow Cytometry 0.5 - 1 ug/million cells in 0.1 ml, Immunohistochemistry-Paraffin 1 - 2 ug/ml, SDS-Page, Immunofluorescence 0.5 - 1.0 ug/ml
Gene Accession No.: P98160
Gene Symbols: HSPG2
Immunogen: Murine EHS laminin preparation
Quantity: 0.2 mg
Primary or Secondary: Primary
Test Specificity: This MAb specifically precipitates heterogeneous material of high MW, identified as perlecan, a major heparan-sulfate proteoglycan (HSPG) within all basement membranes and cell surfaces. It does not cross-react with laminin, fibronectin, or dermatran sulfate proteoglycan. Because of perlecan s strategic location and ability to store and protect growth factors, it has been strongly implicated in the control of tumor cell growth and metastatic behavior. Perlecan possesses angiogenic and growth-promoting attributes primarily by acting as a co-receptor for basic fibroblast growth factor (FGF-2). Suppression of perlecan causes substantial inhibition of neoplastic growth and neovascularization. Thus, perlecan is a potent inducer of neoplasm growth and angiogenesis in vivo and therapeutic interventions targeting this key modulator of tumor progression may improve neoplastic treatment.
Content And Storage: Store at 4C.
Isotype: IgG2a κ
Applications: Flow Cytometry, Immunohistochemistry (Paraffin), SDS-Page, Immunofluorescence
Clone: A7L6
Conjugate: Unconjugated
Formulation: 10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Gene Alias: basement membrane-specific heparan sulfate proteoglycan core protein, endorepellin (domain V region), heparan sulfate proteoglycan 2, HSPG, perlecan, perlecan proteoglycan, PLCSchwartz-Jampel syndrome 1 (chondrodystrophic myotonia), PRCAN, SJA, SJS, SJS1
Host Species: Rat
Purification Method: Protein A or G purified
Regulatory Status: RUO
Gene ID (Entrez): 3339
Target Species: Human, Mouse, Porcine, Fish, Monkey
Form: Purified
Antigen:
Endorepellin/Perlecan/Heparan Sulfate Proteoglycan
Classification:
Monoclonal
Concentration:
0.2mg/mL
Dilution:
Flow Cytometry 0.5 - 1 ug/million cells in 0.1 ml, Immunohistochemistry-Paraffin 1 - 2 ug/ml, SDS-Page, Immunofluorescence 0.5 - 1.0 ug/ml
Gene Accession No.:
P98160
Gene Symbols:
HSPG2
Immunogen:
Murine EHS laminin preparation
Quantity:
0.2 mg
Primary or Secondary:
Primary
Test Specificity:
This MAb specifically precipitates heterogeneous material of high MW, identified as perlecan, a major heparan-sulfate proteoglycan (HSPG) within all basement membranes and cell surfaces. It does not cross-react with laminin, fibronectin, or dermatran sulfate proteoglycan. Because of perlecan s strategic location and ability to store and protect growth factors, it has been strongly implicated in the control of tumor cell growth and metastatic behavior. Perlecan possesses angiogenic and growth-promoting attributes primarily by acting as a co-receptor for basic fibroblast growth factor (FGF-2). Suppression of perlecan causes substantial inhibition of neoplastic growth and neovascularization. Thus, perlecan is a potent inducer of neoplasm growth and angiogenesis in vivo and therapeutic interventions targeting this key modulator of tumor progression may improve neoplastic treatment.
Content And Storage:
Store at 4C.
Isotype:
IgG2a κ
Applications:
Flow Cytometry, Immunohistochemistry (Paraffin), SDS-Page, Immunofluorescence
Clone:
A7L6
Conjugate:
Unconjugated
Formulation:
10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Gene Alias:
basement membrane-specific heparan sulfate proteoglycan core protein, endorepellin (domain V region), heparan sulfate proteoglycan 2, HSPG, perlecan, perlecan proteoglycan, PLCSchwartz-Jampel syndrome 1 (chondrodystrophic myotonia), PRCAN, SJA, SJS, SJS1
Host Species:
Rat
Purification Method:
Protein A or G purified
Regulatory Status:
RUO
Gene ID (Entrez):
3339
Target Species:
Human, Mouse, Porcine, Fish, Monkey
Form:
Purified
Antigen: Endorepellin/Perlecan/Heparan Sulfate Proteoglycan
Classification: Monoclonal
Concentration: 0.2mg/mL
Dilution: Flow Cytometry 0.5 - 1 ug/million cells in 0.1 ml, Immunohistochemistry-Paraffin 1 - 2 ug/ml, Immunofluorescence 0.5 - 1.0 ug/ml
Gene Accession No.: __
Gene Symbols: HSPG2
Immunogen: Murine EHS laminin preparation
Quantity: 0.02 mg
Primary or Secondary: Primary
Test Specificity: This MAb specifically precipitates heterogeneous material of high MW, identified as perlecan, a major heparan-sulfate proteoglycan (HSPG) within all basement membranes and cell surfaces. It does not cross-react with laminin, fibronectin, or dermatran sulfate proteoglycan. Because of perlecan s strategic location and ability to store and protect growth factors, it has been strongly implicated in the control of tumor cell growth and metastatic behavior. Perlecan possesses angiogenic and growth-promoting attributes primarily by acting as a co-receptor for basic fibroblast growth factor (FGF-2). Suppression of perlecan causes substantial inhibition of neoplastic growth and neovascularization. Thus, perlecan is a potent inducer of neoplasm growth and angiogenesis in vivo and therapeutic interventions targeting this key modulator of tumor progression may improve neoplastic treatment
Content And Storage: Store at 4C.
Isotype: IgG2a κ
Applications: Flow Cytometry, Immunohistochemistry (Paraffin), Immunofluorescence
Clone: SPM255
Conjugate: Unconjugated
Formulation: 10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Gene Alias: basement membrane-specific heparan sulfate proteoglycan core protein, endorepellin (domain V region), heparan sulfate proteoglycan 2, HSPG, perlecan, perlecan proteoglycan, PLCSchwartz-Jampel syndrome 1 (chondrodystrophic myotonia), PRCAN, SJA, SJS, SJS1
Host Species: Rat
Purification Method: Protein A or G purified
Regulatory Status: RUO
Gene ID (Entrez): 3339
Target Species: Human, Mouse, Porcine, Fish, Monkey, Primate
Form: Purified
Antigen:
Endorepellin/Perlecan/Heparan Sulfate Proteoglycan
Classification:
Monoclonal
Concentration:
0.2mg/mL
Dilution:
Flow Cytometry 0.5 - 1 ug/million cells in 0.1 ml, Immunohistochemistry-Paraffin 1 - 2 ug/ml, Immunofluorescence 0.5 - 1.0 ug/ml
Gene Accession No.:
__
Gene Symbols:
HSPG2
Immunogen:
Murine EHS laminin preparation
Quantity:
0.02 mg
Primary or Secondary:
Primary
Test Specificity:
This MAb specifically precipitates heterogeneous material of high MW, identified as perlecan, a major heparan-sulfate proteoglycan (HSPG) within all basement membranes and cell surfaces. It does not cross-react with laminin, fibronectin, or dermatran sulfate proteoglycan. Because of perlecan s strategic location and ability to store and protect growth factors, it has been strongly implicated in the control of tumor cell growth and metastatic behavior. Perlecan possesses angiogenic and growth-promoting attributes primarily by acting as a co-receptor for basic fibroblast growth factor (FGF-2). Suppression of perlecan causes substantial inhibition of neoplastic growth and neovascularization. Thus, perlecan is a potent inducer of neoplasm growth and angiogenesis in vivo and therapeutic interventions targeting this key modulator of tumor progression may improve neoplastic treatment
Content And Storage:
Store at 4C.
Isotype:
IgG2a κ
Applications:
Flow Cytometry, Immunohistochemistry (Paraffin), Immunofluorescence
Clone:
SPM255
Conjugate:
Unconjugated
Formulation:
10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Gene Alias:
basement membrane-specific heparan sulfate proteoglycan core protein, endorepellin (domain V region), heparan sulfate proteoglycan 2, HSPG, perlecan, perlecan proteoglycan, PLCSchwartz-Jampel syndrome 1 (chondrodystrophic myotonia), PRCAN, SJA, SJS, SJS1
Host Species:
Rat
Purification Method:
Protein A or G purified
Regulatory Status:
RUO
Gene ID (Entrez):
3339
Target Species:
Human, Mouse, Porcine, Fish, Monkey, Primate
Form:
Purified
Antigen: Endorepellin/Perlecan/Heparan Sulfate Proteoglycan
Classification: Monoclonal
Concentration: 0.2mg/mL
Dilution: Flow Cytometry 0.5 - 1 ug/million cells in 0.1 ml, Immunohistochemistry-Paraffin 1 - 2 ug/ml, Immunofluorescence 0.5 - 1.0 ug/ml
Gene Accession No.: __
Gene Symbols: HSPG2
Immunogen: Murine EHS laminin preparation
Quantity: 0.1 mg
Primary or Secondary: Primary
Test Specificity: This MAb specifically precipitates heterogeneous material of high MW, identified as perlecan, a major heparan-sulfate proteoglycan (HSPG) within all basement membranes and cell surfaces. It does not cross-react with laminin, fibronectin, or dermatran sulfate proteoglycan. Because of perlecan s strategic location and ability to store and protect growth factors, it has been strongly implicated in the control of tumor cell growth and metastatic behavior. Perlecan possesses angiogenic and growth-promoting attributes primarily by acting as a co-receptor for basic fibroblast growth factor (FGF-2). Suppression of perlecan causes substantial inhibition of neoplastic growth and neovascularization. Thus, perlecan is a potent inducer of neoplasm growth and angiogenesis in vivo and therapeutic interventions targeting this key modulator of tumor progression may improve neoplastic treatment
Content And Storage: Store at 4C.
Isotype: IgG2a κ
Applications: Flow Cytometry, Immunohistochemistry (Paraffin), Immunofluorescence
Clone: SPM255
Conjugate: Unconjugated
Formulation: 10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Gene Alias: basement membrane-specific heparan sulfate proteoglycan core protein, endorepellin (domain V region), heparan sulfate proteoglycan 2, HSPG, perlecan, perlecan proteoglycan, PLCSchwartz-Jampel syndrome 1 (chondrodystrophic myotonia), PRCAN, SJA, SJS, SJS1
Host Species: Rat
Purification Method: Protein A or G purified
Regulatory Status: RUO
Gene ID (Entrez): 3339
Target Species: Human, Mouse, Porcine, Fish, Monkey, Primate
Form: Purified
Antigen:
Endorepellin/Perlecan/Heparan Sulfate Proteoglycan
Classification:
Monoclonal
Concentration:
0.2mg/mL
Dilution:
Flow Cytometry 0.5 - 1 ug/million cells in 0.1 ml, Immunohistochemistry-Paraffin 1 - 2 ug/ml, Immunofluorescence 0.5 - 1.0 ug/ml
Gene Accession No.:
__
Gene Symbols:
HSPG2
Immunogen:
Murine EHS laminin preparation
Quantity:
0.1 mg
Primary or Secondary:
Primary
Test Specificity:
This MAb specifically precipitates heterogeneous material of high MW, identified as perlecan, a major heparan-sulfate proteoglycan (HSPG) within all basement membranes and cell surfaces. It does not cross-react with laminin, fibronectin, or dermatran sulfate proteoglycan. Because of perlecan s strategic location and ability to store and protect growth factors, it has been strongly implicated in the control of tumor cell growth and metastatic behavior. Perlecan possesses angiogenic and growth-promoting attributes primarily by acting as a co-receptor for basic fibroblast growth factor (FGF-2). Suppression of perlecan causes substantial inhibition of neoplastic growth and neovascularization. Thus, perlecan is a potent inducer of neoplasm growth and angiogenesis in vivo and therapeutic interventions targeting this key modulator of tumor progression may improve neoplastic treatment
Content And Storage:
Store at 4C.
Isotype:
IgG2a κ
Applications:
Flow Cytometry, Immunohistochemistry (Paraffin), Immunofluorescence
Clone:
SPM255
Conjugate:
Unconjugated
Formulation:
10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Gene Alias:
basement membrane-specific heparan sulfate proteoglycan core protein, endorepellin (domain V region), heparan sulfate proteoglycan 2, HSPG, perlecan, perlecan proteoglycan, PLCSchwartz-Jampel syndrome 1 (chondrodystrophic myotonia), PRCAN, SJA, SJS, SJS1
Host Species:
Rat
Purification Method:
Protein A or G purified
Regulatory Status:
RUO
Gene ID (Entrez):
3339
Target Species:
Human, Mouse, Porcine, Fish, Monkey, Primate
Form:
Purified
Antigen: Endorepellin/Perlecan/Heparan Sulfate Proteoglycan
Classification: Monoclonal
Concentration: 0.2mg/mL
Dilution: Flow Cytometry 0.5 - 1 ug/million cells in 0.1 ml, Immunohistochemistry-Paraffin 1 - 2 ug/ml, Immunofluorescence 0.5 - 1.0 ug/ml
Gene Accession No.: __
Gene Symbols: HSPG2
Immunogen: Murine EHS laminin preparation
Quantity: 0.2 mg
Primary or Secondary: Primary
Test Specificity: This MAb specifically precipitates heterogeneous material of high MW, identified as perlecan, a major heparan-sulfate proteoglycan (HSPG) within all basement membranes and cell surfaces. It does not cross-react with laminin, fibronectin, or dermatran sulfate proteoglycan. Because of perlecan s strategic location and ability to store and protect growth factors, it has been strongly implicated in the control of tumor cell growth and metastatic behavior. Perlecan possesses angiogenic and growth-promoting attributes primarily by acting as a co-receptor for basic fibroblast growth factor (FGF-2). Suppression of perlecan causes substantial inhibition of neoplastic growth and neovascularization. Thus, perlecan is a potent inducer of neoplasm growth and angiogenesis in vivo and therapeutic interventions targeting this key modulator of tumor progression may improve neoplastic treatment
Content And Storage: Store at 4C.
Isotype: IgG2a κ
Applications: Flow Cytometry, Immunohistochemistry (Paraffin), Immunofluorescence
Clone: SPM255
Conjugate: Unconjugated
Formulation: 10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Gene Alias: basement membrane-specific heparan sulfate proteoglycan core protein, endorepellin (domain V region), heparan sulfate proteoglycan 2, HSPG, perlecan, perlecan proteoglycan, PLCSchwartz-Jampel syndrome 1 (chondrodystrophic myotonia), PRCAN, SJA, SJS, SJS1
Host Species: Rat
Purification Method: Protein A or G purified
Regulatory Status: RUO
Gene ID (Entrez): 3339
Target Species: Human, Mouse, Porcine, Fish, Monkey, Primate
Form: Purified
Antigen:
Endorepellin/Perlecan/Heparan Sulfate Proteoglycan
Classification:
Monoclonal
Concentration:
0.2mg/mL
Dilution:
Flow Cytometry 0.5 - 1 ug/million cells in 0.1 ml, Immunohistochemistry-Paraffin 1 - 2 ug/ml, Immunofluorescence 0.5 - 1.0 ug/ml
Gene Accession No.:
__
Gene Symbols:
HSPG2
Immunogen:
Murine EHS laminin preparation
Quantity:
0.2 mg
Primary or Secondary:
Primary
Test Specificity:
This MAb specifically precipitates heterogeneous material of high MW, identified as perlecan, a major heparan-sulfate proteoglycan (HSPG) within all basement membranes and cell surfaces. It does not cross-react with laminin, fibronectin, or dermatran sulfate proteoglycan. Because of perlecan s strategic location and ability to store and protect growth factors, it has been strongly implicated in the control of tumor cell growth and metastatic behavior. Perlecan possesses angiogenic and growth-promoting attributes primarily by acting as a co-receptor for basic fibroblast growth factor (FGF-2). Suppression of perlecan causes substantial inhibition of neoplastic growth and neovascularization. Thus, perlecan is a potent inducer of neoplasm growth and angiogenesis in vivo and therapeutic interventions targeting this key modulator of tumor progression may improve neoplastic treatment
Content And Storage:
Store at 4C.
Isotype:
IgG2a κ
Applications:
Flow Cytometry, Immunohistochemistry (Paraffin), Immunofluorescence
Clone:
SPM255
Conjugate:
Unconjugated
Formulation:
10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Gene Alias:
basement membrane-specific heparan sulfate proteoglycan core protein, endorepellin (domain V region), heparan sulfate proteoglycan 2, HSPG, perlecan, perlecan proteoglycan, PLCSchwartz-Jampel syndrome 1 (chondrodystrophic myotonia), PRCAN, SJA, SJS, SJS1
Host Species:
Rat
Purification Method:
Protein A or G purified
Regulatory Status:
RUO
Gene ID (Entrez):
3339
Target Species:
Human, Mouse, Porcine, Fish, Monkey, Primate
Form:
Purified