NBP24454501
CD27 Ligand/TNFSF7/CD70 Antibody (BU69), Novus Biologicals™
Manufacturer: Fischer Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | NBP24454501-Each-of-1 | In Stock | ₹ 45,004.56 |
NBP24454501 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 45,004.56
GST (18%): ₹ 8,100.821
Total Price: ₹ 53,105.381
Antigen
CD27 Ligand/TNFSF7/CD70
Classification
Monoclonal
Concentration
0.2 mg/mL
Dilution
Flow Cytometry 0.5 - 1 ug/million cells in 0.1 ml, Immunoprecipitation 0.5 - 1 ug/500ug Protein Lysate, Immunohistochemistry-Frozen 0.5 - 1 ug/ml, Immunofluorescence 0.5 - 1.0 ug/ml
Gene Alias
CD27-L, CD27LCD27 ligand, CD27LG, CD70, CD70 molecule, Ki-24 antigen, surface antigen CD70, TNFSF7CD70 antigen, tumor necrosis factor (ligand) superfamily, member 7, Tumor necrosis factor ligand superfamily member 7
Host Species
Mouse
Molecular Weight of Antigen
30 kDa
Quantity
0.1 mg
Research Discipline
Apoptosis
Gene ID (Entrez)
970
Target Species
Human
Form
Purified
Applications
Flow Cytometry, Immunoprecipitation, Immunohistochemistry (Frozen), Immunofluorescence
Clone
BU69
Conjugate
Unconjugated
Formulation
10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Gene Symbols
CD70
Immunogen
Human WM-1 (Waldenstrom s macroglobulinemia) cell line
Purification Method
Protein A or G purified
Regulatory Status
RUO
Primary or Secondary
Primary
Test Specificity
It recognizes a protein of 30kDa, identified as CD70. It is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for TNFRSF27/CD27. It is a surface antigen on activated, but not on resting, T- and B-lymphocytes. It induces proliferation of co-stimulated T cells, enhances the generation of cytolytic T cells, and contributes to T cell activation. This cytokine is also reported to play a role in regulating B-cell activation, cytotoxic function of natural killer cells, and immunoglobulin synthesis. This MAb blocks the interaction between CD27 and CD70, and has been shown to inhibit T cell proliferation induced by dendritic cells.
Content And Storage
Store at 4C.
Isotype
IgG1 κ
Related Products
Description
- Ensure accurate, reproducible results in ELISA, Flow Cytometry, Immunohistochemistry (Frozen), Immunoprecipitation, Immunofluorescence CD27 Ligand/TNFSF7/CD70 Monoclonal specifically detects CD27 Ligand/TNFSF7/CD70 in Human samples
- It is validated for Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunoprecipitation, Immunohistochemistry-Frozen, Immunofluorescence.
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Antigen: CD27 Ligand/TNFSF7/CD70
Classification: Monoclonal
Concentration: 0.2 mg/mL
Dilution: Flow Cytometry 0.5 - 1 ug/million cells in 0.1 ml, Immunoprecipitation 0.5 - 1 ug/500ug Protein Lysate, Immunohistochemistry-Frozen 0.5 - 1 ug/ml, Immunofluorescence 0.5 - 1.0 ug/ml
Gene Alias: CD27-L, CD27LCD27 ligand, CD27LG, CD70, CD70 molecule, Ki-24 antigen, surface antigen CD70, TNFSF7CD70 antigen, tumor necrosis factor (ligand) superfamily, member 7, Tumor necrosis factor ligand superfamily member 7
Host Species: Mouse
Molecular Weight of Antigen: 30 kDa
Quantity: 0.1 mg
Research Discipline: Apoptosis
Gene ID (Entrez): 970
Target Species: Human
Form: Purified
Applications: Flow Cytometry, Immunoprecipitation, Immunohistochemistry (Frozen), Immunofluorescence
Clone: BU69
Conjugate: Unconjugated
Formulation: 10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Gene Symbols: CD70
Immunogen: Human WM-1 (Waldenstrom s macroglobulinemia) cell line
Purification Method: Protein A or G purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: It recognizes a protein of 30kDa, identified as CD70. It is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for TNFRSF27/CD27. It is a surface antigen on activated, but not on resting, T- and B-lymphocytes. It induces proliferation of co-stimulated T cells, enhances the generation of cytolytic T cells, and contributes to T cell activation. This cytokine is also reported to play a role in regulating B-cell activation, cytotoxic function of natural killer cells, and immunoglobulin synthesis. This MAb blocks the interaction between CD27 and CD70, and has been shown to inhibit T cell proliferation induced by dendritic cells.
Content And Storage: Store at 4C.
Isotype: IgG1 κ
Antigen:
CD27 Ligand/TNFSF7/CD70
Classification:
Monoclonal
Concentration:
0.2 mg/mL
Dilution:
Flow Cytometry 0.5 - 1 ug/million cells in 0.1 ml, Immunoprecipitation 0.5 - 1 ug/500ug Protein Lysate, Immunohistochemistry-Frozen 0.5 - 1 ug/ml, Immunofluorescence 0.5 - 1.0 ug/ml
Gene Alias:
CD27-L, CD27LCD27 ligand, CD27LG, CD70, CD70 molecule, Ki-24 antigen, surface antigen CD70, TNFSF7CD70 antigen, tumor necrosis factor (ligand) superfamily, member 7, Tumor necrosis factor ligand superfamily member 7
Host Species:
Mouse
Molecular Weight of Antigen:
30 kDa
Quantity:
0.1 mg
Research Discipline:
Apoptosis
Gene ID (Entrez):
970
Target Species:
Human
Form:
Purified
Applications:
Flow Cytometry, Immunoprecipitation, Immunohistochemistry (Frozen), Immunofluorescence
Clone:
BU69
Conjugate:
Unconjugated
Formulation:
10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Gene Symbols:
CD70
Immunogen:
Human WM-1 (Waldenstrom s macroglobulinemia) cell line
Purification Method:
Protein A or G purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
It recognizes a protein of 30kDa, identified as CD70. It is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for TNFRSF27/CD27. It is a surface antigen on activated, but not on resting, T- and B-lymphocytes. It induces proliferation of co-stimulated T cells, enhances the generation of cytolytic T cells, and contributes to T cell activation. This cytokine is also reported to play a role in regulating B-cell activation, cytotoxic function of natural killer cells, and immunoglobulin synthesis. This MAb blocks the interaction between CD27 and CD70, and has been shown to inhibit T cell proliferation induced by dendritic cells.
Content And Storage:
Store at 4C.
Isotype:
IgG1 κ
Antigen: CD27 Ligand/TNFSF7/CD70
Classification: Monoclonal
Concentration: 0.2 mg/mL
Dilution: Flow Cytometry 0.5 - 1 ug/million cells in 0.1 ml, Immunoprecipitation 0.5 - 1 ug/500ug Protein Lysate, Immunohistochemistry-Frozen 0.5 - 1 ug/ml, Immunofluorescence 0.5 - 1.0 ug/ml
Gene Alias: CD27-L, CD27LCD27 ligand, CD27LG, CD70, CD70 molecule, Ki-24 antigen, surface antigen CD70, TNFSF7CD70 antigen, tumor necrosis factor (ligand) superfamily, member 7, Tumor necrosis factor ligand superfamily member 7
Host Species: Mouse
Molecular Weight of Antigen: 30 kDa
Quantity: 0.2 mg
Research Discipline: Apoptosis
Gene ID (Entrez): 970
Target Species: Human
Form: Purified
Applications: Flow Cytometry, Immunoprecipitation, Immunohistochemistry (Frozen), Immunofluorescence
Clone: BU69
Conjugate: Unconjugated
Formulation: 10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Gene Symbols: CD70
Immunogen: Human WM-1 (Waldenstrom s macroglobulinemia) cell line
Purification Method: Protein A or G purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: It recognizes a protein of 30kDa, identified as CD70. It is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for TNFRSF27/CD27. It is a surface antigen on activated, but not on resting, T- and B-lymphocytes. It induces proliferation of co-stimulated T cells, enhances the generation of cytolytic T cells, and contributes to T cell activation. This cytokine is also reported to play a role in regulating B-cell activation, cytotoxic function of natural killer cells, and immunoglobulin synthesis. This MAb blocks the interaction between CD27 and CD70, and has been shown to inhibit T cell proliferation induced by dendritic cells.
Content And Storage: Store at 4C.
Isotype: IgG1 κ
Antigen:
CD27 Ligand/TNFSF7/CD70
Classification:
Monoclonal
Concentration:
0.2 mg/mL
Dilution:
Flow Cytometry 0.5 - 1 ug/million cells in 0.1 ml, Immunoprecipitation 0.5 - 1 ug/500ug Protein Lysate, Immunohistochemistry-Frozen 0.5 - 1 ug/ml, Immunofluorescence 0.5 - 1.0 ug/ml
Gene Alias:
CD27-L, CD27LCD27 ligand, CD27LG, CD70, CD70 molecule, Ki-24 antigen, surface antigen CD70, TNFSF7CD70 antigen, tumor necrosis factor (ligand) superfamily, member 7, Tumor necrosis factor ligand superfamily member 7
Host Species:
Mouse
Molecular Weight of Antigen:
30 kDa
Quantity:
0.2 mg
Research Discipline:
Apoptosis
Gene ID (Entrez):
970
Target Species:
Human
Form:
Purified
Applications:
Flow Cytometry, Immunoprecipitation, Immunohistochemistry (Frozen), Immunofluorescence
Clone:
BU69
Conjugate:
Unconjugated
Formulation:
10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Gene Symbols:
CD70
Immunogen:
Human WM-1 (Waldenstrom s macroglobulinemia) cell line
Purification Method:
Protein A or G purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
It recognizes a protein of 30kDa, identified as CD70. It is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for TNFRSF27/CD27. It is a surface antigen on activated, but not on resting, T- and B-lymphocytes. It induces proliferation of co-stimulated T cells, enhances the generation of cytolytic T cells, and contributes to T cell activation. This cytokine is also reported to play a role in regulating B-cell activation, cytotoxic function of natural killer cells, and immunoglobulin synthesis. This MAb blocks the interaction between CD27 and CD70, and has been shown to inhibit T cell proliferation induced by dendritic cells.
Content And Storage:
Store at 4C.
Isotype:
IgG1 κ
Antigen: CPS1
Classification: Monoclonal
Concentration: 0.2mg/mL
Dilution: Immunohistochemistry-Paraffin 0.25 - 0.5 ug/ml, Immunofluorescence 0.5 - 1.0 ug/ml
Gene Alias: carbamoyl-phosphate synthase [ammonia], mitochondrial, carbamoyl-phosphate synthase 1, mitochondrial, carbamoyl-phosphate synthetase 1, mitochondrial, carbamoylphosphate synthetase I, Carbamoyl-phosphate synthetase I, CPSase I, CPSASE1, EC 6.3.4.16
Host Species: Mouse
Molecular Weight of Antigen: __
Quantity: 0.02 mg
Research Discipline: __
Gene ID (Entrez): 1373
Target Species: Human, Canine
Form: Purified
Applications: Immunohistochemistry (Paraffin), Immunofluorescence
Clone: CPS1/1022
Conjugate: Unconjugated
Formulation: 10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Gene Symbols: CPS1
Immunogen: Recombinant human CPS1 protein
Purification Method: Protein A or G purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: This MAb recognizes a protein of 165kDa, identified as carbamoyl phosphate synthetase 1 (CPS1). This mitochondrial enzyme catalyzes synthesis of carbamoyl phosphate from ammonia and bicarbonate. This reaction is the first committed step of the urea cycle, which is important in the removal of excess urea from cells.Deficiency of CPS1 is an autosomal recessive disorder that causes hyperammonemia. CPS1 is a hepatocyte specific protein that localizes to the mitochondria of hepatocytes. It is a sensitive marker for distinguishing hepatocellular carcinomas (HCC) from other metastatic carcinomas as well as cholangio-carcinomas. HCC s occur primarily in the stomach, but they are also found in many other organs. CPS1 may also be a useful marker for intestinal metaplasia. Reportedly, strong expression of CPS1 correlates with smaller tumor size and longer patient survival. Occasionally, CPS1 is also found in gastric carcinomas as well as in a few other non-hepatic tumors.
Content And Storage: Store at 4C.
Isotype: IgG1
Antigen:
CPS1
Classification:
Monoclonal
Concentration:
0.2mg/mL
Dilution:
Immunohistochemistry-Paraffin 0.25 - 0.5 ug/ml, Immunofluorescence 0.5 - 1.0 ug/ml
Gene Alias:
carbamoyl-phosphate synthase [ammonia], mitochondrial, carbamoyl-phosphate synthase 1, mitochondrial, carbamoyl-phosphate synthetase 1, mitochondrial, carbamoylphosphate synthetase I, Carbamoyl-phosphate synthetase I, CPSase I, CPSASE1, EC 6.3.4.16
Host Species:
Mouse
Molecular Weight of Antigen:
__
Quantity:
0.02 mg
Research Discipline:
__
Gene ID (Entrez):
1373
Target Species:
Human, Canine
Form:
Purified
Applications:
Immunohistochemistry (Paraffin), Immunofluorescence
Clone:
CPS1/1022
Conjugate:
Unconjugated
Formulation:
10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Gene Symbols:
CPS1
Immunogen:
Recombinant human CPS1 protein
Purification Method:
Protein A or G purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
This MAb recognizes a protein of 165kDa, identified as carbamoyl phosphate synthetase 1 (CPS1). This mitochondrial enzyme catalyzes synthesis of carbamoyl phosphate from ammonia and bicarbonate. This reaction is the first committed step of the urea cycle, which is important in the removal of excess urea from cells.Deficiency of CPS1 is an autosomal recessive disorder that causes hyperammonemia. CPS1 is a hepatocyte specific protein that localizes to the mitochondria of hepatocytes. It is a sensitive marker for distinguishing hepatocellular carcinomas (HCC) from other metastatic carcinomas as well as cholangio-carcinomas. HCC s occur primarily in the stomach, but they are also found in many other organs. CPS1 may also be a useful marker for intestinal metaplasia. Reportedly, strong expression of CPS1 correlates with smaller tumor size and longer patient survival. Occasionally, CPS1 is also found in gastric carcinomas as well as in a few other non-hepatic tumors.
Content And Storage:
Store at 4C.
Isotype:
IgG1
Antigen: CPS1
Classification: Monoclonal
Concentration: 0.2mg/mL
Dilution: Immunohistochemistry-Paraffin 0.25 - 0.5 ug/ml, Immunofluorescence 0.5 - 1.0 ug/ml
Gene Alias: carbamoyl-phosphate synthase [ammonia], mitochondrial, carbamoyl-phosphate synthase 1, mitochondrial, carbamoyl-phosphate synthetase 1, mitochondrial, carbamoylphosphate synthetase I, Carbamoyl-phosphate synthetase I, CPSase I, CPSASE1, EC 6.3.4.16
Host Species: Mouse
Molecular Weight of Antigen: __
Quantity: 0.1 mg
Research Discipline: __
Gene ID (Entrez): 1373
Target Species: Human, Canine
Form: Purified
Applications: Immunohistochemistry (Paraffin), Immunofluorescence
Clone: CPS1/1022
Conjugate: Unconjugated
Formulation: 10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Gene Symbols: CPS1
Immunogen: Recombinant human CPS1 protein
Purification Method: Protein A or G purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: This MAb recognizes a protein of 165kDa, identified as carbamoyl phosphate synthetase 1 (CPS1). This mitochondrial enzyme catalyzes synthesis of carbamoyl phosphate from ammonia and bicarbonate. This reaction is the first committed step of the urea cycle, which is important in the removal of excess urea from cells.Deficiency of CPS1 is an autosomal recessive disorder that causes hyperammonemia. CPS1 is a hepatocyte specific protein that localizes to the mitochondria of hepatocytes. It is a sensitive marker for distinguishing hepatocellular carcinomas (HCC) from other metastatic carcinomas as well as cholangio-carcinomas. HCC s occur primarily in the stomach, but they are also found in many other organs. CPS1 may also be a useful marker for intestinal metaplasia. Reportedly, strong expression of CPS1 correlates with smaller tumor size and longer patient survival. Occasionally, CPS1 is also found in gastric carcinomas as well as in a few other non-hepatic tumors.
Content And Storage: Store at 4C.
Isotype: IgG1
Antigen:
CPS1
Classification:
Monoclonal
Concentration:
0.2mg/mL
Dilution:
Immunohistochemistry-Paraffin 0.25 - 0.5 ug/ml, Immunofluorescence 0.5 - 1.0 ug/ml
Gene Alias:
carbamoyl-phosphate synthase [ammonia], mitochondrial, carbamoyl-phosphate synthase 1, mitochondrial, carbamoyl-phosphate synthetase 1, mitochondrial, carbamoylphosphate synthetase I, Carbamoyl-phosphate synthetase I, CPSase I, CPSASE1, EC 6.3.4.16
Host Species:
Mouse
Molecular Weight of Antigen:
__
Quantity:
0.1 mg
Research Discipline:
__
Gene ID (Entrez):
1373
Target Species:
Human, Canine
Form:
Purified
Applications:
Immunohistochemistry (Paraffin), Immunofluorescence
Clone:
CPS1/1022
Conjugate:
Unconjugated
Formulation:
10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Gene Symbols:
CPS1
Immunogen:
Recombinant human CPS1 protein
Purification Method:
Protein A or G purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
This MAb recognizes a protein of 165kDa, identified as carbamoyl phosphate synthetase 1 (CPS1). This mitochondrial enzyme catalyzes synthesis of carbamoyl phosphate from ammonia and bicarbonate. This reaction is the first committed step of the urea cycle, which is important in the removal of excess urea from cells.Deficiency of CPS1 is an autosomal recessive disorder that causes hyperammonemia. CPS1 is a hepatocyte specific protein that localizes to the mitochondria of hepatocytes. It is a sensitive marker for distinguishing hepatocellular carcinomas (HCC) from other metastatic carcinomas as well as cholangio-carcinomas. HCC s occur primarily in the stomach, but they are also found in many other organs. CPS1 may also be a useful marker for intestinal metaplasia. Reportedly, strong expression of CPS1 correlates with smaller tumor size and longer patient survival. Occasionally, CPS1 is also found in gastric carcinomas as well as in a few other non-hepatic tumors.
Content And Storage:
Store at 4C.
Isotype:
IgG1