NBP247669B
Cytokeratin, pan Antibody (KRT/457) - Azide and BSA Free, Novus Biologicals™
Manufacturer: Fischer Scientific
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Antigen
pan Cytokeratin
Classification
Monoclonal
Concentration
1.0 mg/mL
Dilution
Western Blot : 0.5 - 1.0 ug/ml, Flow Cytometry : 0.5 - 1 ug/million cells in 0.1 ml, Immunohistochemistry-Paraffin : 0.5 - 1.0 ug/ml, Immunofluorescence : 0.5 - 1.0 ug/ml, CyTOF-ready
Gene Symbols
KRT1
Immunogen
Keratin-enriched preparation from cultured human epithelial cells
Quantity
0.2 mg
Research Discipline
Cytoskeleton Markers, Protein Kinase, Signal Transduction
Gene ID (Entrez)
3848
Target Species
Human, Mouse, Rat, Porcine, Amphibian, Bovine, Guinea Pig, Goat, Monkey
Form
Purified
Applications
Western Blot, Flow Cytometry, Immunohistochemistry (Paraffin), Immunofluorescence, CyTOF
Clone
KRT/457
Conjugate
Unconjugated
Formulation
PBS with No Preservative
Host Species
Mouse
Purification Method
Protein A or G purified
Regulatory Status
RUO
Primary or Secondary
Primary
Test Specificity
Twenty human keratins are resolved with two-dimensional gel electrophoresis into acidic (pI 6.0) subfamilies. This antibody recognizes acidic (Type I or LMW) and basic (Type II or HMW) cytokeratins, including 59kDa (CK4); 58kDa (CK5); 56kDa (CK6); 52kDa (CK8); 56.5kDa (CK10); 53kDa (CK13) and 45kDa (CK18). This is a broad-spectrum antibody, which has been reported to differentiate epithelial tumors from non-epithelial tumors. Many studies have shown the usefulness of keratins as markers in cancer research and tumor diagnosis.
Content And Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Isotype
IgG1
Related Products
Description
- Cytokeratin, pan Monoclonal specifically detects Cytokeratin, pan in Human, Mouse, Rat, Porcine, Amphibian, Bovine, Guinea Pig, Goat, Monkey samples
- It is validated for Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunofluorescence, CyTOF-ready.
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Antigen: pan Cytokeratin
Classification: Monoclonal
Concentration: 1.0 mg/mL
Dilution: Western Blot : 0.5 - 1.0 ug/ml, Flow Cytometry : 0.5 - 1 ug/million cells in 0.1 ml, Immunohistochemistry-Paraffin : 0.5 - 1.0 ug/ml, Immunofluorescence : 0.5 - 1.0 ug/ml, CyTOF-ready
Gene Symbols: KRT1
Immunogen: Keratin-enriched preparation from cultured human epithelial cells
Quantity: 0.2 mg
Research Discipline: Cytoskeleton Markers, Protein Kinase, Signal Transduction
Gene ID (Entrez): 3848
Target Species: Human, Mouse, Rat, Porcine, Amphibian, Bovine, Guinea Pig, Goat, Monkey
Form: Purified
Applications: Western Blot, Flow Cytometry, Immunohistochemistry (Paraffin), Immunofluorescence, CyTOF
Clone: KRT/457
Conjugate: Unconjugated
Formulation: PBS with No Preservative
Host Species: Mouse
Purification Method: Protein A or G purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: Twenty human keratins are resolved with two-dimensional gel electrophoresis into acidic (pI 6.0) subfamilies. This antibody recognizes acidic (Type I or LMW) and basic (Type II or HMW) cytokeratins, including 59kDa (CK4); 58kDa (CK5); 56kDa (CK6); 52kDa (CK8); 56.5kDa (CK10); 53kDa (CK13) and 45kDa (CK18). This is a broad-spectrum antibody, which has been reported to differentiate epithelial tumors from non-epithelial tumors. Many studies have shown the usefulness of keratins as markers in cancer research and tumor diagnosis.
Content And Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Isotype: IgG1
Antigen:
pan Cytokeratin
Classification:
Monoclonal
Concentration:
1.0 mg/mL
Dilution:
Western Blot : 0.5 - 1.0 ug/ml, Flow Cytometry : 0.5 - 1 ug/million cells in 0.1 ml, Immunohistochemistry-Paraffin : 0.5 - 1.0 ug/ml, Immunofluorescence : 0.5 - 1.0 ug/ml, CyTOF-ready
Gene Symbols:
KRT1
Immunogen:
Keratin-enriched preparation from cultured human epithelial cells
Quantity:
0.2 mg
Research Discipline:
Cytoskeleton Markers, Protein Kinase, Signal Transduction
Gene ID (Entrez):
3848
Target Species:
Human, Mouse, Rat, Porcine, Amphibian, Bovine, Guinea Pig, Goat, Monkey
Form:
Purified
Applications:
Western Blot, Flow Cytometry, Immunohistochemistry (Paraffin), Immunofluorescence, CyTOF
Clone:
KRT/457
Conjugate:
Unconjugated
Formulation:
PBS with No Preservative
Host Species:
Mouse
Purification Method:
Protein A or G purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
Twenty human keratins are resolved with two-dimensional gel electrophoresis into acidic (pI 6.0) subfamilies. This antibody recognizes acidic (Type I or LMW) and basic (Type II or HMW) cytokeratins, including 59kDa (CK4); 58kDa (CK5); 56kDa (CK6); 52kDa (CK8); 56.5kDa (CK10); 53kDa (CK13) and 45kDa (CK18). This is a broad-spectrum antibody, which has been reported to differentiate epithelial tumors from non-epithelial tumors. Many studies have shown the usefulness of keratins as markers in cancer research and tumor diagnosis.
Content And Storage:
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Isotype:
IgG1
Antigen: HLA-DR
Classification: Monoclonal
Concentration: __
Dilution: Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Paraffin, Immunofluorescence
Gene Symbols: HLA-DRA
Immunogen: Activated human peripheral blood mononuclear cells
Quantity: 0.1 mL
Research Discipline: Adaptive Immunity, B Cell Development and Differentiation Markers, Cell Biology, Cellular Markers, Diabetes Research, Immunology, Major Histocompatibility Complexes
Gene ID (Entrez): 3122
Target Species: Human, Monkey, Mouse (Negative)
Form: Purified
Applications: Flow Cytometry, Immunohistochemistry, Immunohistochemistry (Paraffin), Immunofluorescence
Clone: LN-3
Conjugate: FITC
Formulation: PBS with 0.05% Sodium Azide
Host Species: Mouse
Purification Method: Protein A or G purified
Regulatory Status: __
Primary or Secondary: Primary
Test Specificity: This monoclonal antibody reacts with a 28kDa chain of HLA-DRB1 antigen, a member of MHC class II molecules. It does not cross react with HLA-DP and HLA-DQ. The L243 antibody recognizes a different epitope than the LN3 monoclonal antibody, and these antibodies do not cross-block binding to each others respective epitopes. HLA-DR is a heterodimeric cell surface glycoprotein comprised of a 36kDa alpha (heavy) chain and a 28kDa beta (light) chain. It is expressed on B-cells, activated T-cells, monocytes/macrophages, dendritic cells and other non-professional APCs. In conjunction with the CD3/TCR complex and CD4 molecules, HLA-DR is critical for efficient peptide presentation to CD4+ T cells. It is an excellent histiocytic marker in paraffin sections producing intense staining. True histiocytic neoplasms are similarly positive. HLA-DR antigens also occur on a variety of epithelial cells and their corresponding neoplastic counterparts. Loss of HLA-DR expression is related to tumor microenvironment and predicts adverse outcome in diffuse large B-cell lymphoma.
Content And Storage: Store at 4C in the dark.
Isotype: IgG2b κ
Antigen:
HLA-DR
Classification:
Monoclonal
Concentration:
__
Dilution:
Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Paraffin, Immunofluorescence
Gene Symbols:
HLA-DRA
Immunogen:
Activated human peripheral blood mononuclear cells
Quantity:
0.1 mL
Research Discipline:
Adaptive Immunity, B Cell Development and Differentiation Markers, Cell Biology, Cellular Markers, Diabetes Research, Immunology, Major Histocompatibility Complexes
Gene ID (Entrez):
3122
Target Species:
Human, Monkey, Mouse (Negative)
Form:
Purified
Applications:
Flow Cytometry, Immunohistochemistry, Immunohistochemistry (Paraffin), Immunofluorescence
Clone:
LN-3
Conjugate:
FITC
Formulation:
PBS with 0.05% Sodium Azide
Host Species:
Mouse
Purification Method:
Protein A or G purified
Regulatory Status:
__
Primary or Secondary:
Primary
Test Specificity:
This monoclonal antibody reacts with a 28kDa chain of HLA-DRB1 antigen, a member of MHC class II molecules. It does not cross react with HLA-DP and HLA-DQ. The L243 antibody recognizes a different epitope than the LN3 monoclonal antibody, and these antibodies do not cross-block binding to each others respective epitopes. HLA-DR is a heterodimeric cell surface glycoprotein comprised of a 36kDa alpha (heavy) chain and a 28kDa beta (light) chain. It is expressed on B-cells, activated T-cells, monocytes/macrophages, dendritic cells and other non-professional APCs. In conjunction with the CD3/TCR complex and CD4 molecules, HLA-DR is critical for efficient peptide presentation to CD4+ T cells. It is an excellent histiocytic marker in paraffin sections producing intense staining. True histiocytic neoplasms are similarly positive. HLA-DR antigens also occur on a variety of epithelial cells and their corresponding neoplastic counterparts. Loss of HLA-DR expression is related to tumor microenvironment and predicts adverse outcome in diffuse large B-cell lymphoma.
Content And Storage:
Store at 4C in the dark.
Isotype:
IgG2b κ
Antigen: HLA-DR
Classification: Monoclonal
Concentration: __
Dilution: Western Blot, Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Paraffin, Immunofluorescence
Gene Symbols: HLA-DRA
Immunogen: Activated human peripheral blood mononuclear cells
Quantity: 0.1 mL
Research Discipline: Adaptive Immunity, B Cell Development and Differentiation Markers, Cell Biology, Cellular Markers, Diabetes Research, Immunology, Major Histocompatibility Complexes
Gene ID (Entrez): 3122
Target Species: Human, Monkey, Mouse (Negative)
Form: Purified
Applications: Western Blot, Flow Cytometry, Immunohistochemistry, Immunohistochemistry (Paraffin), Immunofluorescence
Clone: LN-3
Conjugate: DyLight 680
Formulation: 50mM Sodium Borate with 0.05% Sodium Azide
Host Species: Mouse
Purification Method: Protein A or G purified
Regulatory Status: __
Primary or Secondary: Primary
Test Specificity: This monoclonal antibody reacts with a 28kDa chain of HLA-DRB1 antigen, a member of MHC class II molecules. It does not cross react with HLA-DP and HLA-DQ. The L243 antibody recognizes a different epitope than the LN3 monoclonal antibody, and these antibodies do not cross-block binding to each others respective epitopes. HLA-DR is a heterodimeric cell surface glycoprotein comprised of a 36kDa alpha (heavy) chain and a 28kDa beta (light) chain. It is expressed on B-cells, activated T-cells, monocytes/macrophages, dendritic cells and other non-professional APCs. In conjunction with the CD3/TCR complex and CD4 molecules, HLA-DR is critical for efficient peptide presentation to CD4+ T cells. It is an excellent histiocytic marker in paraffin sections producing intense staining. True histiocytic neoplasms are similarly positive. HLA-DR antigens also occur on a variety of epithelial cells and their corresponding neoplastic counterparts. Loss of HLA-DR expression is related to tumor microenvir
Content And Storage: Store at 4C in the dark.
Isotype: IgG2b κ
Antigen:
HLA-DR
Classification:
Monoclonal
Concentration:
__
Dilution:
Western Blot, Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Paraffin, Immunofluorescence
Gene Symbols:
HLA-DRA
Immunogen:
Activated human peripheral blood mononuclear cells
Quantity:
0.1 mL
Research Discipline:
Adaptive Immunity, B Cell Development and Differentiation Markers, Cell Biology, Cellular Markers, Diabetes Research, Immunology, Major Histocompatibility Complexes
Gene ID (Entrez):
3122
Target Species:
Human, Monkey, Mouse (Negative)
Form:
Purified
Applications:
Western Blot, Flow Cytometry, Immunohistochemistry, Immunohistochemistry (Paraffin), Immunofluorescence
Clone:
LN-3
Conjugate:
DyLight 680
Formulation:
50mM Sodium Borate with 0.05% Sodium Azide
Host Species:
Mouse
Purification Method:
Protein A or G purified
Regulatory Status:
__
Primary or Secondary:
Primary
Test Specificity:
This monoclonal antibody reacts with a 28kDa chain of HLA-DRB1 antigen, a member of MHC class II molecules. It does not cross react with HLA-DP and HLA-DQ. The L243 antibody recognizes a different epitope than the LN3 monoclonal antibody, and these antibodies do not cross-block binding to each others respective epitopes. HLA-DR is a heterodimeric cell surface glycoprotein comprised of a 36kDa alpha (heavy) chain and a 28kDa beta (light) chain. It is expressed on B-cells, activated T-cells, monocytes/macrophages, dendritic cells and other non-professional APCs. In conjunction with the CD3/TCR complex and CD4 molecules, HLA-DR is critical for efficient peptide presentation to CD4+ T cells. It is an excellent histiocytic marker in paraffin sections producing intense staining. True histiocytic neoplasms are similarly positive. HLA-DR antigens also occur on a variety of epithelial cells and their corresponding neoplastic counterparts. Loss of HLA-DR expression is related to tumor microenvir
Content And Storage:
Store at 4C in the dark.
Isotype:
IgG2b κ
Antigen: HLA-DR
Classification: Monoclonal
Concentration: __
Dilution: Western Blot, Immunohistochemistry, Immunohistochemistry-Paraffin
Gene Symbols: HLA-DRA
Immunogen: Activated human peripheral blood mononuclear cells
Quantity: 0.1 mL
Research Discipline: Adaptive Immunity, B Cell Development and Differentiation Markers, Cell Biology, Cellular Markers, Diabetes Research, Immunology, Major Histocompatibility Complexes
Gene ID (Entrez): 3122
Target Species: Human, Monkey, Mouse (Negative)
Form: Purified
Applications: Western Blot, Immunohistochemistry, Immunohistochemistry (Paraffin)
Clone: LN-3
Conjugate: HRP
Formulation: PBS with No Preservative
Host Species: Mouse
Purification Method: Protein A or G purified
Regulatory Status: __
Primary or Secondary: Primary
Test Specificity: This monoclonal antibody reacts with a 28kDa chain of HLA-DRB1 antigen, a member of MHC class II molecules. It does not cross react with HLA-DP and HLA-DQ. The L243 antibody recognizes a different epitope than the LN3 monoclonal antibody, and these antibodies do not cross-block binding to each others respective epitopes. HLA-DR is a heterodimeric cell surface glycoprotein comprised of a 36kDa alpha (heavy) chain and a 28kDa beta (light) chain. It is expressed on B-cells, activated T-cells, monocytes/macrophages, dendritic cells and other non-professional APCs. In conjunction with the CD3/TCR complex and CD4 molecules, HLA-DR is critical for efficient peptide presentation to CD4+ T cells. It is an excellent histiocytic marker in paraffin sections producing intense staining. True histiocytic neoplasms are similarly positive. HLA-DR antigens also occur on a variety of epithelial cells and their corresponding neoplastic counterparts. Loss of HLA-DR expression is related to tumor microenvir
Content And Storage: Store at 4C in the dark.
Isotype: IgG2b κ
Antigen:
HLA-DR
Classification:
Monoclonal
Concentration:
__
Dilution:
Western Blot, Immunohistochemistry, Immunohistochemistry-Paraffin
Gene Symbols:
HLA-DRA
Immunogen:
Activated human peripheral blood mononuclear cells
Quantity:
0.1 mL
Research Discipline:
Adaptive Immunity, B Cell Development and Differentiation Markers, Cell Biology, Cellular Markers, Diabetes Research, Immunology, Major Histocompatibility Complexes
Gene ID (Entrez):
3122
Target Species:
Human, Monkey, Mouse (Negative)
Form:
Purified
Applications:
Western Blot, Immunohistochemistry, Immunohistochemistry (Paraffin)
Clone:
LN-3
Conjugate:
HRP
Formulation:
PBS with No Preservative
Host Species:
Mouse
Purification Method:
Protein A or G purified
Regulatory Status:
__
Primary or Secondary:
Primary
Test Specificity:
This monoclonal antibody reacts with a 28kDa chain of HLA-DRB1 antigen, a member of MHC class II molecules. It does not cross react with HLA-DP and HLA-DQ. The L243 antibody recognizes a different epitope than the LN3 monoclonal antibody, and these antibodies do not cross-block binding to each others respective epitopes. HLA-DR is a heterodimeric cell surface glycoprotein comprised of a 36kDa alpha (heavy) chain and a 28kDa beta (light) chain. It is expressed on B-cells, activated T-cells, monocytes/macrophages, dendritic cells and other non-professional APCs. In conjunction with the CD3/TCR complex and CD4 molecules, HLA-DR is critical for efficient peptide presentation to CD4+ T cells. It is an excellent histiocytic marker in paraffin sections producing intense staining. True histiocytic neoplasms are similarly positive. HLA-DR antigens also occur on a variety of epithelial cells and their corresponding neoplastic counterparts. Loss of HLA-DR expression is related to tumor microenvir
Content And Storage:
Store at 4C in the dark.
Isotype:
IgG2b κ