NBP247853G

Bcl-2 Antibody (BCL2/782 + BCL2/796), DyLight 488, Novus Biologicals™

Manufacturer: Novus Biologicals

Select a Size

Pack Size SKU Availability Price
Each of 1 NBP247853G-Each-of-1 In Stock ₹ 56,298.48

NBP247853G - Each of 1

₹ 56,298.48

In Stock

Quantity

1

Base Price: ₹ 56,298.48

GST (18%): ₹ 10,133.726

Total Price: ₹ 66,432.206

Antigen

Bcl-2

Classification

Monoclonal

Conjugate

DyLight 488

Formulation

50mM Sodium Borate with 0.05% Sodium Azide

Gene Symbols

BCL2

Immunogen

Recombinant full-length human bcl-2 protein (Uniprot: P10415)

Quantity

0.1 mL

Primary or Secondary

Primary

Test Specificity

This antibody recognizes a protein of 25-26kDa, identified as the Bcl-2 lpha oncoprotein. It shows no cross-reaction with Bcl-x or Bax protein. Expression of Bcl-2 lpha oncoprotein inhibits the programmed cell death (apoptosis). In most follicular lymphomas, neoplastic germinal centers express high levels of Bcl-2 lpha protein, whereas the normal or hyperplastic germinal centers are negative. Consequently, this antibody is valuable when distinguishing between reactive and neoplastic follicular proliferation in lymph node biopsies. It may also be used in distinguishing between those follicular lymphomas that express Bcl-2 protein and the small number in which the neoplastic cells are Bcl-2 negative.

Content And Storage

Store at 4C in the dark.

Isotype

IgG1 κ

Applications

Western Blot, Flow Cytometry, Immunohistochemistry, Immunohistochemistry (Paraffin), Immunofluorescence

Clone

BCL2/782 + BCL2/796

Dilution

Western Blot, Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Paraffin, Immunofluorescence

Gene Alias

apoptosis regulator Bcl-2, B-cell CLL/lymphoma 2, Bcl-2

Host Species

Mouse

Purification Method

Protein A or G purified

Research Discipline

Apoptosis, Autophagy, Biologically Active Proteins, Cancer, Cellular Markers, Mitochondrial Mediated Pathway, Mitophagy, Oncogenes, Phospho Specific, Tumor Suppressors

Gene ID (Entrez)

596

Target Species

Human

Form

Purified

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Description

  • Bcl-2 Monoclonal specifically detects Bcl-2 in Human samples
  • It is validated for Western Blot, Immunohistochemistry, Immunohistochemistry-Paraffin.

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Show Difference

Img

Novus Biologicals

NBP247853G

--


Antigen:
Bcl-2

Classification:
Monoclonal

Conjugate:
DyLight 488

Formulation:
50mM Sodium Borate with 0.05% Sodium Azide

Gene Symbols:
BCL2

Immunogen:
Recombinant full-length human bcl-2 protein (Uniprot: P10415)

Quantity:
0.1 mL

Primary or Secondary:
Primary

Test Specificity:
This antibody recognizes a protein of 25-26kDa, identified as the Bcl-2 lpha oncoprotein. It shows no cross-reaction with Bcl-x or Bax protein. Expression of Bcl-2 lpha oncoprotein inhibits the programmed cell death (apoptosis). In most follicular lymphomas, neoplastic germinal centers express high levels of Bcl-2 lpha protein, whereas the normal or hyperplastic germinal centers are negative. Consequently, this antibody is valuable when distinguishing between reactive and neoplastic follicular proliferation in lymph node biopsies. It may also be used in distinguishing between those follicular lymphomas that express Bcl-2 protein and the small number in which the neoplastic cells are Bcl-2 negative.

Content And Storage:
Store at 4C in the dark.

Isotype:
IgG1 κ

Applications:
Western Blot, Flow Cytometry, Immunohistochemistry, Immunohistochemistry (Paraffin), Immunofluorescence

Clone:
BCL2/782 + BCL2/796

Dilution:
Western Blot, Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Paraffin, Immunofluorescence

Gene Alias:
apoptosis regulator Bcl-2, B-cell CLL/lymphoma 2, Bcl-2

Host Species:
Mouse

Purification Method:
Protein A or G purified

Research Discipline:
Apoptosis, Autophagy, Biologically Active Proteins, Cancer, Cellular Markers, Mitochondrial Mediated Pathway, Mitophagy, Oncogenes, Phospho Specific, Tumor Suppressors

Gene ID (Entrez):
596

Target Species:
Human

Form:
Purified

Img

Novus Biologicals

NBP247853UV

--


Antigen:
Bcl-2

Classification:
Monoclonal

Conjugate:
DyLight 350

Formulation:
50mM Sodium Borate with 0.05% Sodium Azide

Gene Symbols:
BCL2

Immunogen:
Recombinant full-length human bcl-2 protein (Uniprot: P10415)

Quantity:
0.1 mL

Primary or Secondary:
Primary

Test Specificity:
This antibody recognizes a protein of 25-26kDa, identified as the Bcl-2 lpha oncoprotein. It shows no cross-reaction with Bcl-x or Bax protein. Expression of Bcl-2 lpha oncoprotein inhibits the programmed cell death (apoptosis). In most follicular lymphomas, neoplastic germinal centers express high levels of Bcl-2 lpha protein, whereas the normal or hyperplastic germinal centers are negative. Consequently, this antibody is valuable when distinguishing between reactive and neoplastic follicular proliferation in lymph node biopsies. It may also be used in distinguishing between those follicular lymphomas that express Bcl-2 protein and the small number in which the neoplastic cells are Bcl-2 negative.

Content And Storage:
Store at 4C in the dark.

Isotype:
IgG1 κ

Applications:
Western Blot, Flow Cytometry, Immunohistochemistry, Immunohistochemistry (Paraffin), Immunofluorescence

Clone:
BCL2/782 + BCL2/796

Dilution:
Western Blot, Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Paraffin, Immunofluorescence

Gene Alias:
apoptosis regulator Bcl-2, B-cell CLL/lymphoma 2, Bcl-2

Host Species:
Mouse

Purification Method:
Protein A or G purified

Research Discipline:
Apoptosis, Autophagy, Biologically Active Proteins, Cancer, Cellular Markers, Mitochondrial Mediated Pathway, Mitophagy, Oncogenes, Phospho Specific, Tumor Suppressors

Gene ID (Entrez):
596

Target Species:
Human

Form:
Purified

Img

Fischer Scientific

NBP247854A

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Antigen:
Androgen R/NR3C4

Classification:
Monoclonal

Conjugate:
Unconjugated

Formulation:
PBS with No Preservative

Gene Symbols:
AR

Immunogen:
A synthetic peptide, aa 299-315, (STEDTAEYSPFKGGYTK) of human AR.

Quantity:
0.1 mg

Primary or Secondary:
Primary

Test Specificity:
Recognizes a protein of 110kDa, which is identified as androgen receptor (AR). It reacts with full length, and the newly described A form of the receptor. It does not cross react with estrogen, progesterone, or glucocorticoid receptors. The expression of AR is reportedly inversely correlated with histologic grade i.e. well differentiated prostate tumors show higher expression than the poorly differentiated tumors. In prostate cancer, AR has been proposed, as a marker of hormone-responsiveness and thus it may be useful in identifying patients likely to benefit from anti-androgen therapy. Anti-androgen receptor has been useful clinically in differentiating morpheaform basal cell carcinoma (mBCC) from desmoplastic trichoepithelioma (DTE) in the skin.This MAb is superb for staining of formalin/paraffin tissues.

Content And Storage:
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Isotype:
IgG1 κ

Applications:
Flow Cytometry, Immunohistochemistry (Paraffin), Immunofluorescence, CyTOF

Clone:
AR441

Dilution:
Flow Cytometry : 0.5 - 1 ug/million cells in 0.1 ml, Immunohistochemistry-Paraffin : 0.5 - 1.0 ug/ml, Immunofluorescence : 0.5 - 1.0 ug/ml, CyTOF-ready

Gene Alias:
AIS, androgen receptor, DHTRTFM, Dihydrotestosterone receptorHYSP1, HUMARA, NR3C4KD, Nuclear receptor subfamily 3 group C member 4, SMAX1SBMA, spinal and bulbar muscular atrophy

Host Species:
Mouse

Purification Method:
Protein A or G purified

Research Discipline:
Breast Cancer, Cancer, Cellular Markers

Gene ID (Entrez):
367

Target Species:
Human, Mouse (Negative)

Form:
Purified

Img

Fischer Scientific

NBP247854B

--


Antigen:
Androgen R/NR3C4

Classification:
Monoclonal

Conjugate:
Unconjugated

Formulation:
PBS with No Preservative

Gene Symbols:
AR

Immunogen:
A synthetic peptide, aa 299-315, (STEDTAEYSPFKGGYTK) of human AR.

Quantity:
0.2 mg

Primary or Secondary:
Primary

Test Specificity:
Recognizes a protein of 110kDa, which is identified as androgen receptor (AR). It reacts with full length, and the newly described A form of the receptor. It does not cross react with estrogen, progesterone, or glucocorticoid receptors. The expression of AR is reportedly inversely correlated with histologic grade i.e. well differentiated prostate tumors show higher expression than the poorly differentiated tumors. In prostate cancer, AR has been proposed, as a marker of hormone-responsiveness and thus it may be useful in identifying patients likely to benefit from anti-androgen therapy. Anti-androgen receptor has been useful clinically in differentiating morpheaform basal cell carcinoma (mBCC) from desmoplastic trichoepithelioma (DTE) in the skin.This MAb is superb for staining of formalin/paraffin tissues.

Content And Storage:
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Isotype:
IgG1 κ

Applications:
Flow Cytometry, Immunohistochemistry (Paraffin), Immunofluorescence, CyTOF

Clone:
AR441

Dilution:
Flow Cytometry : 0.5 - 1 ug/million cells in 0.1 ml, Immunohistochemistry-Paraffin : 0.5 - 1.0 ug/ml, Immunofluorescence : 0.5 - 1.0 ug/ml, CyTOF-ready

Gene Alias:
AIS, androgen receptor, DHTRTFM, Dihydrotestosterone receptorHYSP1, HUMARA, NR3C4KD, Nuclear receptor subfamily 3 group C member 4, SMAX1SBMA, spinal and bulbar muscular atrophy

Host Species:
Mouse

Purification Method:
Protein A or G purified

Research Discipline:
Breast Cancer, Cancer, Cellular Markers

Gene ID (Entrez):
367

Target Species:
Human, Mouse (Negative)

Form:
Purified