NBP247857IR

Androgen R/NR3C4 Antibody (AR441 + DHTR/882), DyLight 755, Novus Biologicals™

Manufacturer: Novus Biologicals

Select a Size

Pack Size SKU Availability Price
Each of 1 NBP247857IR-Each-of-1 In Stock ₹ 55,271.76

NBP247857IR - Each of 1

₹ 55,271.76

In Stock

Quantity

1

Base Price: ₹ 55,271.76

GST (18%): ₹ 9,948.917

Total Price: ₹ 65,220.677

Antigen

Androgen R/NR3C4

Classification

Monoclonal

Conjugate

DyLight 755

Formulation

50mM Sodium Borate with 0.05% Sodium Azide

Gene Symbols

AR

Immunogen

A synthetic peptide, aa 302-318 of human Androgen R/NR3C4 (Androgen R/NR3C4441); Recombinant human DHTR protein (DHTR/882) (Uniprot: P10275)

Quantity

0.1 mL

Primary or Secondary

Primary

Test Specificity

Recognizes a protein of 110kDa, which is identified as androgen receptor (AR). It reacts with full length, and the newly described A form of the receptor. It does not cross react with estrogen, progesterone, or glucocorticoid receptors. The expression of AR is reportedly inversely correlated with histologic grade i.e. well differentiated prostate tumors show higher expression than the poorly differentiated tumors. In prostate cancer, AR has been proposed, as a marker of hormone-responsiveness and thus it may be useful in identifying patients likely to benefit from anti-androgen therapy. Anti-androgen receptor has been useful clinically in differentiating morpheaform basal cell carcinoma (mBCC) from desmoplastic trichoepithelioma (DTE) in the skin. This monoclonal antibody is superb for staining of formalin/paraffin tissues.

Content And Storage

Store at 4C in the dark.

Isotype

IgG1 κ

Applications

Immunohistochemistry, Immunohistochemistry (Paraffin), Immunofluorescence

Clone

AR441 + DHTR/882

Dilution

Immunohistochemistry, Immunohistochemistry-Paraffin, Immunofluorescence

Gene Alias

AIS, androgen receptor, DHTRTFM, Dihydrotestosterone receptorHYSP1, HUMARA, NR3C4KD, Nuclear receptor subfamily 3 group C member 4, SMAX1SBMA, spinal and bulbar muscular atrophy

Host Species

Mouse

Purification Method

Protein A or G purified

Research Discipline

Breast Cancer, Cancer, Cellular Markers, Phospho Specific

Gene ID (Entrez)

367

Target Species

Human, Mouse (Negative)

Form

Purified

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Description

  • Androgen R/NR3C4 Monoclonal specifically detects Androgen R/NR3C4 in Human, Mouse (Negative) samples
  • It is validated for Immunohistochemistry, Immunohistochemistry-Paraffin.

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Show Difference

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Novus Biologicals

NBP247857IR

--


Antigen:
Androgen R/NR3C4

Classification:
Monoclonal

Conjugate:
DyLight 755

Formulation:
50mM Sodium Borate with 0.05% Sodium Azide

Gene Symbols:
AR

Immunogen:
A synthetic peptide, aa 302-318 of human Androgen R/NR3C4 (Androgen R/NR3C4441); Recombinant human DHTR protein (DHTR/882) (Uniprot: P10275)

Quantity:
0.1 mL

Primary or Secondary:
Primary

Test Specificity:
Recognizes a protein of 110kDa, which is identified as androgen receptor (AR). It reacts with full length, and the newly described A form of the receptor. It does not cross react with estrogen, progesterone, or glucocorticoid receptors. The expression of AR is reportedly inversely correlated with histologic grade i.e. well differentiated prostate tumors show higher expression than the poorly differentiated tumors. In prostate cancer, AR has been proposed, as a marker of hormone-responsiveness and thus it may be useful in identifying patients likely to benefit from anti-androgen therapy. Anti-androgen receptor has been useful clinically in differentiating morpheaform basal cell carcinoma (mBCC) from desmoplastic trichoepithelioma (DTE) in the skin. This monoclonal antibody is superb for staining of formalin/paraffin tissues.

Content And Storage:
Store at 4C in the dark.

Isotype:
IgG1 κ

Applications:
Immunohistochemistry, Immunohistochemistry (Paraffin), Immunofluorescence

Clone:
AR441 + DHTR/882

Dilution:
Immunohistochemistry, Immunohistochemistry-Paraffin, Immunofluorescence

Gene Alias:
AIS, androgen receptor, DHTRTFM, Dihydrotestosterone receptorHYSP1, HUMARA, NR3C4KD, Nuclear receptor subfamily 3 group C member 4, SMAX1SBMA, spinal and bulbar muscular atrophy

Host Species:
Mouse

Purification Method:
Protein A or G purified

Research Discipline:
Breast Cancer, Cancer, Cellular Markers, Phospho Specific

Gene ID (Entrez):
367

Target Species:
Human, Mouse (Negative)

Form:
Purified

Img

Novus Biologicals

NBP247857R

--


Antigen:
Androgen R/NR3C4

Classification:
Monoclonal

Conjugate:
DyLight 550

Formulation:
50mM Sodium Borate with 0.05% Sodium Azide

Gene Symbols:
AR

Immunogen:
A synthetic peptide, aa 302-318 of human Androgen R/NR3C4 (Androgen R/NR3C4441); Recombinant human DHTR protein (DHTR/882) (Uniprot: P10275)

Quantity:
0.1 mL

Primary or Secondary:
Primary

Test Specificity:
Recognizes a protein of 110kDa, which is identified as androgen receptor (AR). It reacts with full length, and the newly described A form of the receptor. It does not cross react with estrogen, progesterone, or glucocorticoid receptors. The expression of AR is reportedly inversely correlated with histologic grade i.e. well differentiated prostate tumors show higher expression than the poorly differentiated tumors. In prostate cancer, AR has been proposed, as a marker of hormone-responsiveness and thus it may be useful in identifying patients likely to benefit from anti-androgen therapy. Anti-androgen receptor has been useful clinically in differentiating morpheaform basal cell carcinoma (mBCC) from desmoplastic trichoepithelioma (DTE) in the skin. This monoclonal antibody is superb for staining of formalin/paraffin tissues.

Content And Storage:
Store at 4C in the dark.

Isotype:
IgG1 κ

Applications:
Immunohistochemistry, Immunohistochemistry (Paraffin), Immunofluorescence

Clone:
AR441 + DHTR/882

Dilution:
Immunohistochemistry, Immunohistochemistry-Paraffin, Immunofluorescence

Gene Alias:
AIS, androgen receptor, DHTRTFM, Dihydrotestosterone receptorHYSP1, HUMARA, NR3C4KD, Nuclear receptor subfamily 3 group C member 4, SMAX1SBMA, spinal and bulbar muscular atrophy

Host Species:
Mouse

Purification Method:
Protein A or G purified

Research Discipline:
Breast Cancer, Cancer, Cellular Markers, Phospho Specific

Gene ID (Entrez):
367

Target Species:
Human, Mouse (Negative)

Form:
Purified

Img

Novus Biologicals

NBP247858FR

--


Antigen:
WT1

Classification:
Monoclonal

Conjugate:
DyLight 680

Formulation:
50mM Sodium Borate with 0.05% Sodium Azide

Gene Symbols:
WT1

Immunogen:
Recombinant full length human WT1 protein (WT1/857); Recombinant fragment aa1-181 of human WT1 (6F-H2) (Uniprot: P19544)

Quantity:
0.1 mL

Primary or Secondary:
Primary

Test Specificity:
Recognizes a 47-55kDa-tumor suppressor protein, identified as Wilms tumor and mesothelioma. WT1 protein has been identified in proliferative mesothelial cells, malignant mesothelioma, ovarian carcinoma, gonadoblastoma, nephroblastoma, and desmoplastic small round cell tumor. Lung adenocarcinomas rarely stain positive with this antibody. WT1 protein expression in mesothelial cells has become a reliable marker for the diagnosis of mesotheliomas.

Content And Storage:
Store at 4C in the dark.

Isotype:
IgG1 κ

Applications:
Flow Cytometry, Immunohistochemistry, Immunohistochemistry (Paraffin), Immunofluorescence

Clone:
WT1/857 + 6F-H2

Dilution:
Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Paraffin, Immunofluorescence

Gene Alias:
AWT1, NPHS4GUD, WAGR, Wilms tumor 1, Wilms tumor protein, WIT-2, WT33

Host Species:
Mouse

Purification Method:
Protein A or G purified

Research Discipline:
Angiogenesis, Cancer, Cell Cycle and Replication, Cellular Markers, Chromatin Research, Tumor Suppressors

Gene ID (Entrez):
7490

Target Species:
Human, Mouse, Rat

Form:
Purified

Img

Novus Biologicals

NBP247858H

--


Antigen:
WT1

Classification:
Monoclonal

Conjugate:
HRP

Formulation:
PBS with No Preservative

Gene Symbols:
WT1

Immunogen:
Recombinant full length human WT1 protein (WT1/857); Recombinant fragment aa1-181 of human WT1 (6F-H2) (Uniprot: P19544)

Quantity:
0.1 mL

Primary or Secondary:
Primary

Test Specificity:
Recognizes a 47-55kDa-tumor suppressor protein, identified as Wilms tumor and mesothelioma. WT1 protein has been identified in proliferative mesothelial cells, malignant mesothelioma, ovarian carcinoma, gonadoblastoma, nephroblastoma, and desmoplastic small round cell tumor. Lung adenocarcinomas rarely stain positive with this antibody. WT1 protein expression in mesothelial cells has become a reliable marker for the diagnosis of mesotheliomas.

Content And Storage:
Store at 4C in the dark.

Isotype:
IgG1 κ

Applications:
Immunohistochemistry, Immunohistochemistry (Paraffin)

Clone:
WT1/857 + 6F-H2

Dilution:
Immunohistochemistry, Immunohistochemistry-Paraffin

Gene Alias:
AWT1, NPHS4GUD, WAGR, Wilms tumor 1, Wilms tumor protein, WIT-2, WT33

Host Species:
Mouse

Purification Method:
Protein A or G purified

Research Discipline:
Angiogenesis, Cancer, Cell Cycle and Replication, Cellular Markers, Chromatin Research, Tumor Suppressors

Gene ID (Entrez):
7490

Target Species:
Human, Mouse, Rat

Form:
Purified