NBP248121

alpha-Fetoprotein/AFP Antibody (C2) - IHC-Prediluted, Novus Biologicals™

Manufacturer: Novus Biologicals

Select a Size

Pack Size SKU Availability Price
Each of 1 NBP248121-Each-of-1 In Stock ₹ 43,336.14

NBP248121 - Each of 1

₹ 43,336.14

In Stock

Quantity

1

Base Price: ₹ 43,336.14

GST (18%): ₹ 7,800.505

Total Price: ₹ 51,136.645

Antigen

alpha-Fetoprotein/AFP

Classification

Monoclonal

Conjugate

Unconjugated

Formulation

10mM PBS and 0.05% BSA with 0.05% Sodium Azide

Gene Symbols

AFP

Immunogen

Alpha feto protein (AFP) Purified from serum of a hepatoma patient (Uniprot: P02771)

Purification Method

Protein A or G purified

Regulatory Status

RUO

Primary or Secondary

Primary

Test Specificity

It recognizes an oncofetal glycoprotein with a single chain of 70kDa, which is identified as alpha fetoprotein (AFP) (ISOBM TD-2 workshop). This monoclonal antibody is highly specific to AFP and shows no cross-reaction with other oncofetal antigens or serum albumin. AFP is normally synthesized in the liver, intestinal tract, and yolk sac of the fetus. Antibody to AFP has been shown to be useful in detecting hepatocellular carcinomas (HCC) and germ cell neoplasms, especially yolk sac tumors.

Content And Storage

Store at 4C.

Isotype

IgG1 κ

Applications

Immunohistochemistry (Paraffin)

Clone

C2

Dilution

Immunohistochemistry-Paraffin

Gene Alias

Alpha-1-fetoprotein, Alpha-fetoglobulin, alpha-fetoprotein, FETA, HP, HPAFP

Host Species

Mouse

Molecular Weight of Antigen

70 kDa

Quantity

7 mL

Research Discipline

Cancer, Cancer Stem Cells, GPCR, Stem Cell Markers, Tumor Biomarkers

Gene ID (Entrez)

174

Target Species

Human, Mouse, Bovine (Negative), Canine (Negative), Rat (Negative)

Form

Purified

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Description

  • alpha-Fetoprotein/AFP Monoclonal specifically detects alpha-Fetoprotein/AFP in Human, Mouse, Bovine (Negative), Canine (Negative), Rat (Negative) samples
  • It is validated for Immunohistochemistry, Immunohistochemistry-Paraffin.

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Img

Novus Biologicals

NBP248121

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Antigen:
alpha-Fetoprotein/AFP

Classification:
Monoclonal

Conjugate:
Unconjugated

Formulation:
10mM PBS and 0.05% BSA with 0.05% Sodium Azide

Gene Symbols:
AFP

Immunogen:
Alpha feto protein (AFP) Purified from serum of a hepatoma patient (Uniprot: P02771)

Purification Method:
Protein A or G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
It recognizes an oncofetal glycoprotein with a single chain of 70kDa, which is identified as alpha fetoprotein (AFP) (ISOBM TD-2 workshop). This monoclonal antibody is highly specific to AFP and shows no cross-reaction with other oncofetal antigens or serum albumin. AFP is normally synthesized in the liver, intestinal tract, and yolk sac of the fetus. Antibody to AFP has been shown to be useful in detecting hepatocellular carcinomas (HCC) and germ cell neoplasms, especially yolk sac tumors.

Content And Storage:
Store at 4C.

Isotype:
IgG1 κ

Applications:
Immunohistochemistry (Paraffin)

Clone:
C2

Dilution:
Immunohistochemistry-Paraffin

Gene Alias:
Alpha-1-fetoprotein, Alpha-fetoglobulin, alpha-fetoprotein, FETA, HP, HPAFP

Host Species:
Mouse

Molecular Weight of Antigen:
70 kDa

Quantity:
7 mL

Research Discipline:
Cancer, Cancer Stem Cells, GPCR, Stem Cell Markers, Tumor Biomarkers

Gene ID (Entrez):
174

Target Species:
Human, Mouse, Bovine (Negative), Canine (Negative), Rat (Negative)

Form:
Purified

Img

Novus Biologicals

NBP248122

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Antigen:
HLA DRB1

Classification:
Monoclonal

Conjugate:
Unconjugated

Formulation:
10mM PBS and 0.05% BSA with 0.05% Sodium Azide

Gene Symbols:
HLA-DRB1

Immunogen:
Activated human peripheral blood mononuclear cells

Purification Method:
Protein A or G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
This monoclonal antibody reacts with a 28kDa chain of HLA-DRB1 antigen, a member of MHC class II molecules. It does not cross react with HLA-DP and HLA-DQ. The L243 antibody recognizes a different epitope than the LN3 monoclonal antibody, and these antibodies do not cross-block binding to each others respective epitopes. HLA-DR is a heterodimeric cell surface glycoprotein comprised of a 36kDa alpha (heavy) chain and a 28kDa beta (light) chain. It is expressed on B-cells, activated T-cells, monocytes/macrophages, dendritic cells and other non-professional APCs. In conjunction with the CD3/TCR complex and CD4 molecules, HLA-DR is critical for efficient peptide presentation to CD4+ T cells. It is an excellent histiocytic marker in paraffin sections producing intense staining. True histiocytic neoplasms are similarly positive. HLA-DR antigens also occur on a variety of epithelial cells and their corresponding neoplastic counterparts. Loss of HLA-DR expression is related to tumor microenvironment and predicts adverse outcome in diffuse large B-cell lymphoma.

Content And Storage:
Store at 4C.

Isotype:
IgG2b κ

Applications:
Immunohistochemistry (Paraffin)

Clone:
SPM288

Dilution:
Immunohistochemistry-Paraffin

Gene Alias:
Clone P2-beta-3, DR1, DR-1, DR12, DR-12, DR13, DR-13, DR14, DR-14, DR16, DR-16, DR4, DR-4, DR5, DR-5, DR7, DR-7, DR8, DR-8, DR9, DR-9, DRB1, DRw10, DRw11, DRw8, DW2.2/DR2.2, FLJ75017, FLJ76359, HLA class II antigen beta chain, HLA class II histocompatibility antigen, DR-1 beta chain, HLA-DR1B, HLA-DRB, HLA-DRB1*, HLA-DRB2, HLA-DR-beta 1, human leucocyte antigen DRB1, leucocyte antigen DR beta 1 chain, leucocyte antigen DRB1, lymphocyte antigen DRB1, major histocompatibility complex, class II, DR beta 1, MHC class II antigen DRB1*1, MHC class II antigen DRB1*10, MHC class II antigen DRB1*11, MHC class II antigen DRB1*12, MHC class II antigen DRB1*13, MHC class II antigen DRB1*14, MHC class II antigen DRB1*15, MHC class II antigen DRB1*16, MHC class II antigen DRB1*3, MHC class II antigen DRB1*4, MHC class II antigen DRB1*7, MHC class II antigen DRB1*8, MHC class II antigen DRB1*9, MHC class II antigen HLA-DR13, MHC class II HLA-DR beta 1 chain, MHC class II HLA-DR-beta cell surface gly

Host Species:
Mouse

Molecular Weight of Antigen:
__

Quantity:
7 mL

Research Discipline:
Asthma, Immunology

Gene ID (Entrez):
3123

Target Species:
Human, Monkey, Mouse (Negative)

Form:
Purified

Img

Novus Biologicals

NBP248123

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Antigen:
HLA DRB1

Classification:
Monoclonal

Conjugate:
Unconjugated

Formulation:
10mM PBS and 0.05% BSA with 0.05% Sodium Azide

Gene Symbols:
HLA-DRB1

Immunogen:
Activated human peripheral blood mononuclear cells

Purification Method:
Protein A or G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
This monoclonal antibody reacts with a 28kDa chain of HLA-DRB1 antigen, a member of MHC class II molecules. It does not cross react with HLA-DP and HLA-DQ. The L243 antibody recognizes a different epitope than the LN3 monoclonal antibody, and these antibodies do not cross-block binding to each others respective epitopes. HLA-DR is a heterodimeric cell surface glycoprotein comprised of a 36kDa alpha (heavy) chain and a 28kDa beta (light) chain. It is expressed on B-cells, activated T-cells, monocytes/macrophages, dendritic cells and other non-professional APCs. In conjunction with the CD3/TCR complex and CD4 molecules, HLA-DR is critical for efficient peptide presentation to CD4+ T cells. It is an excellent histiocytic marker in paraffin sections producing intense staining. True histiocytic neoplasms are similarly positive. HLA-DR antigens also occur on a variety of epithelial cells and their corresponding neoplastic counterparts. Loss of HLA-DR expression is related to tumor microenvironment and predicts adverse outcome in diffuse large B-cell lymphoma.

Content And Storage:
Store at 4C.

Isotype:
IgG2b κ

Applications:
Immunohistochemistry (Paraffin)

Clone:
SPM423

Dilution:
Immunohistochemistry-Paraffin

Gene Alias:
Clone P2-beta-3, DR1, DR-1, DR12, DR-12, DR13, DR-13, DR14, DR-14, DR16, DR-16, DR4, DR-4, DR5, DR-5, DR7, DR-7, DR8, DR-8, DR9, DR-9, DRB1, DRw10, DRw11, DRw8, DW2.2/DR2.2, FLJ75017, FLJ76359, HLA class II antigen beta chain, HLA class II histocompatibility antigen, DR-1 beta chain, HLA-DR1B, HLA-DRB, HLA-DRB1*, HLA-DRB2, HLA-DR-beta 1, human leucocyte antigen DRB1, leucocyte antigen DR beta 1 chain, leucocyte antigen DRB1, lymphocyte antigen DRB1, major histocompatibility complex, class II, DR beta 1, MHC class II antigen DRB1*1, MHC class II antigen DRB1*10, MHC class II antigen DRB1*11, MHC class II antigen DRB1*12, MHC class II antigen DRB1*13, MHC class II antigen DRB1*14, MHC class II antigen DRB1*15, MHC class II antigen DRB1*16, MHC class II antigen DRB1*3, MHC class II antigen DRB1*4, MHC class II antigen DRB1*7, MHC class II antigen DRB1*8, MHC class II antigen DRB1*9, MHC class II antigen HLA-DR13, MHC class II HLA-DR beta 1 chain, MHC class II HLA-DR-beta cell surface gly

Host Species:
Mouse

Molecular Weight of Antigen:
__

Quantity:
7 mL

Research Discipline:
Asthma, Immunology

Gene ID (Entrez):
3123

Target Species:
Human, Monkey, Mouse (Negative)

Form:
Purified

Img

Novus Biologicals

NBP248124

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Antigen:
Cytokeratin 7

Classification:
Monoclonal

Conjugate:
Unconjugated

Formulation:
10mM PBS and 0.05% BSA with 0.05% Sodium Azide

Gene Symbols:
KRT7

Immunogen:
OTN 11, ovarian carcinoma cell line

Purification Method:
Protein A or G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
It recognizes an intermediate filament protein (IFP) of 55kDa, which is identified as cytokeratin 7. This monoclonal antibody is highly specific to cytokeratin 7 and shows no cross-reaction with other IFPs. Cytokeratin 7 is a basic cytokeratin, which is found in most glandular and transitional epithelia but not in the stratified squamous epithelia. Keratin 7 is expressed in the epithelial cells of ovary, lung, and breast but not of colon, prostate, or gastrointestinal tract. This monoclonal antibody is highly useful in distinguishing ovarian carcinomas (keratin 7+) from colon carcinomas (keratin 7-).

Content And Storage:
Store at 4C.

Isotype:
IgG1 κ

Applications:
Immunohistochemistry (Paraffin)

Clone:
SPM270

Dilution:
Immunohistochemistry-Paraffin

Gene Alias:
CK7, CK-7, cytokeratin 7, Cytokeratin-7, K2C7, K7keratin, 55K type II cytoskeletal, keratin 7, keratin, type II cytoskeletal 7, keratin-7, MGC129731, MGC3625, Sarcolectin, SCLkeratin, simple epithelial type I, K7, type II mesothelial keratin K7, Type-II keratin Kb7

Host Species:
Mouse

Molecular Weight of Antigen:
55 kDa

Quantity:
7 mL

Research Discipline:
Cytoskeleton Markers

Gene ID (Entrez):
3855

Target Species:
Human

Form:
Purified