NBP248256
Bax Antibody (BAX/962) - IHC-Prediluted, Novus Biologicals™
Manufacturer: Novus Biologicals
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | NBP248256-Each-of-1 | In Stock | ₹ 45,860.16 |
NBP248256 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 45,860.16
GST (18%): ₹ 8,254.829
Total Price: ₹ 54,114.989
Antigen
Bax
Classification
Monoclonal
Conjugate
Unconjugated
Formulation
10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Gene Symbols
BAX
Immunogen
Recombinant full-length human BAX protein. (Uniprot: Q07812)
Purification Method
Protein A or G purified
Regulatory Status
RUO
Primary or Secondary
Primary
Test Specificity
Recognizes a protein of 21kDa, identified as the Bax protein. This monoclonal antibody is highly specific to Bax and shows no cross-reaction with Bcl-2 or Bcl-X protein. Bcl-2 blocks cell death following a variety of stimuli. Bax has extensive amino acid homology with Bcl-2 and it homodimerizes and forms heterodimers with Bcl-2. Overexpression of Bax accelerates apoptotic death induced by cytokine deprivation in an IL-3 dependent cell line, and Bax also counters the death repressor activity of Bcl-2.
Content And Storage
Store at 4C.
Isotype
IgG1 κ
Applications
Immunohistochemistry (Paraffin)
Clone
BAX/962
Dilution
Immunohistochemistry-Paraffin
Gene Alias
apoptosis regulator BAX, BCL2-associated X protein, Bcl2-L-4, BCL2L4bcl2-L-4, Bcl-2-like protein 4
Host Species
Mouse
Molecular Weight of Antigen
21 kDa
Quantity
7 mL
Research Discipline
Apoptosis, Cancer, Core ESC Like Genes, Stem Cell Markers, Tumor Suppressors
Gene ID (Entrez)
581
Target Species
Human, Monkey, Mouse (Negative), Rat (Negative)
Form
Purified
Related Products
Description
- Bax Monoclonal specifically detects Bax in Human, Monkey, Mouse (Negative), Rat (Negative) samples
- It is validated for Immunohistochemistry, Immunohistochemistry-Paraffin.
Compare Similar Items
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Antigen: Bax
Classification: Monoclonal
Conjugate: Unconjugated
Formulation: 10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Gene Symbols: BAX
Immunogen: Recombinant full-length human BAX protein. (Uniprot: Q07812)
Purification Method: Protein A or G purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: Recognizes a protein of 21kDa, identified as the Bax protein. This monoclonal antibody is highly specific to Bax and shows no cross-reaction with Bcl-2 or Bcl-X protein. Bcl-2 blocks cell death following a variety of stimuli. Bax has extensive amino acid homology with Bcl-2 and it homodimerizes and forms heterodimers with Bcl-2. Overexpression of Bax accelerates apoptotic death induced by cytokine deprivation in an IL-3 dependent cell line, and Bax also counters the death repressor activity of Bcl-2.
Content And Storage: Store at 4C.
Isotype: IgG1 κ
Applications: Immunohistochemistry (Paraffin)
Clone: BAX/962
Dilution: Immunohistochemistry-Paraffin
Gene Alias: apoptosis regulator BAX, BCL2-associated X protein, Bcl2-L-4, BCL2L4bcl2-L-4, Bcl-2-like protein 4
Host Species: Mouse
Molecular Weight of Antigen: 21 kDa
Quantity: 7 mL
Research Discipline: Apoptosis, Cancer, Core ESC Like Genes, Stem Cell Markers, Tumor Suppressors
Gene ID (Entrez): 581
Target Species: Human, Monkey, Mouse (Negative), Rat (Negative)
Form: Purified
Antigen:
Bax
Classification:
Monoclonal
Conjugate:
Unconjugated
Formulation:
10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Gene Symbols:
BAX
Immunogen:
Recombinant full-length human BAX protein. (Uniprot: Q07812)
Purification Method:
Protein A or G purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
Recognizes a protein of 21kDa, identified as the Bax protein. This monoclonal antibody is highly specific to Bax and shows no cross-reaction with Bcl-2 or Bcl-X protein. Bcl-2 blocks cell death following a variety of stimuli. Bax has extensive amino acid homology with Bcl-2 and it homodimerizes and forms heterodimers with Bcl-2. Overexpression of Bax accelerates apoptotic death induced by cytokine deprivation in an IL-3 dependent cell line, and Bax also counters the death repressor activity of Bcl-2.
Content And Storage:
Store at 4C.
Isotype:
IgG1 κ
Applications:
Immunohistochemistry (Paraffin)
Clone:
BAX/962
Dilution:
Immunohistochemistry-Paraffin
Gene Alias:
apoptosis regulator BAX, BCL2-associated X protein, Bcl2-L-4, BCL2L4bcl2-L-4, Bcl-2-like protein 4
Host Species:
Mouse
Molecular Weight of Antigen:
21 kDa
Quantity:
7 mL
Research Discipline:
Apoptosis, Cancer, Core ESC Like Genes, Stem Cell Markers, Tumor Suppressors
Gene ID (Entrez):
581
Target Species:
Human, Monkey, Mouse (Negative), Rat (Negative)
Form:
Purified
Antigen: Melanoma Marker (MART-1 + Tyrosinase + gp100)
Classification: Monoclonal
Conjugate: Unconjugated
Formulation: PBS with 0.05% BSA. with 0.05% Sodium Azide
Gene Symbols: __
Immunogen: Recombinant hMART-1 protein (M2-7C10; M2-9E3); Recombinant tyrosinase protein (T311); Extract of pigmented melanoma metastases from lymph nodes (HMB45)
Purification Method: Protein A or G purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: This antibody cocktail recognizes three melanoma-specific proteins, which include MART-1, Tyrosinase and gp100. MART-1 is a newly identified melanocyte differentiation antigen recognized by autologous cytotoxic T lymphocytes. Tyrosinase is one of the targets for cytotoxic T-cell recognition in melanoma patients. Function of gp100 is not known but it is reported to be a useful marker for melanocytes and melanomas. This cocktail of three markers is designed for extremely sensitive labeling of formalin-fixed, paraffin-embedded melanomas and other tumors showing melanocytic differentiation.
Content And Storage: Store at 4C.
Isotype: IgG2b λ, IgG2a κ, IgG1 κ
Applications: Immunohistochemistry, Immunohistochemistry (Paraffin)
Clone: M2-7C10 + M2-9E3 + T311 + HMB45
Dilution: Immunohistochemistry-Paraffin
Gene Alias: MART1, MART-1, melan-A, MLANA
Host Species: Mouse
Molecular Weight of Antigen: __
Quantity: 7 mL
Research Discipline: __
Gene ID (Entrez): 2315
Target Species: Human
Form: Purified
Antigen:
Melanoma Marker (MART-1 + Tyrosinase + gp100)
Classification:
Monoclonal
Conjugate:
Unconjugated
Formulation:
PBS with 0.05% BSA. with 0.05% Sodium Azide
Gene Symbols:
__
Immunogen:
Recombinant hMART-1 protein (M2-7C10; M2-9E3); Recombinant tyrosinase protein (T311); Extract of pigmented melanoma metastases from lymph nodes (HMB45)
Purification Method:
Protein A or G purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
This antibody cocktail recognizes three melanoma-specific proteins, which include MART-1, Tyrosinase and gp100. MART-1 is a newly identified melanocyte differentiation antigen recognized by autologous cytotoxic T lymphocytes. Tyrosinase is one of the targets for cytotoxic T-cell recognition in melanoma patients. Function of gp100 is not known but it is reported to be a useful marker for melanocytes and melanomas. This cocktail of three markers is designed for extremely sensitive labeling of formalin-fixed, paraffin-embedded melanomas and other tumors showing melanocytic differentiation.
Content And Storage:
Store at 4C.
Isotype:
IgG2b λ, IgG2a κ, IgG1 κ
Applications:
Immunohistochemistry, Immunohistochemistry (Paraffin)
Clone:
M2-7C10 + M2-9E3 + T311 + HMB45
Dilution:
Immunohistochemistry-Paraffin
Gene Alias:
MART1, MART-1, melan-A, MLANA
Host Species:
Mouse
Molecular Weight of Antigen:
__
Quantity:
7 mL
Research Discipline:
__
Gene ID (Entrez):
2315
Target Species:
Human
Form:
Purified
Antigen: Melanoma Marker (MART-1 + Tyrosinase + gp100)
Classification: Monoclonal
Conjugate: Unconjugated
Formulation: PBS with 0.05% BSA. with 0.05% Sodium Azide
Gene Symbols: __
Immunogen: Recombinant hMART-1 protein (A103); Recombinant tyrosinase protein (T311); Extract of pigmented melanoma metastases from lymph nodes (HMB45)
Purification Method: Protein A or G purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: This antibody cocktail recognizes three melanoma-specific proteins, which include MART-1, Tyrosinase and gp100. MART-1 is a newly identified melanocyte differentiation antigen recognized by autologous cytotoxic T lymphocytes. Tyrosinase is one of the targets for cytotoxic T-cell recognition in melanoma patients. The function of gp100 is not known but it is reported to be a useful marker for melanocytes and melanomas. This cocktail of three markers is designed for extremely sensitive labeling of formalin-fixed, paraffin-embedded melanomas and other tumors showing melanocytic differentiation.
Content And Storage: Store at 4C.
Isotype: IgG1, IgG2a κ
Applications: Immunohistochemistry (Paraffin)
Clone: A103 + T311 + HMB45
Dilution: Immunohistochemistry, Immunohistochemistry-Paraffin
Gene Alias: MART1, MART-1, melan-A, MLANA
Host Species: Mouse
Molecular Weight of Antigen: __
Quantity: 7 mL
Research Discipline: __
Gene ID (Entrez): 2315
Target Species: Human
Form: Purified
Antigen:
Melanoma Marker (MART-1 + Tyrosinase + gp100)
Classification:
Monoclonal
Conjugate:
Unconjugated
Formulation:
PBS with 0.05% BSA. with 0.05% Sodium Azide
Gene Symbols:
__
Immunogen:
Recombinant hMART-1 protein (A103); Recombinant tyrosinase protein (T311); Extract of pigmented melanoma metastases from lymph nodes (HMB45)
Purification Method:
Protein A or G purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
This antibody cocktail recognizes three melanoma-specific proteins, which include MART-1, Tyrosinase and gp100. MART-1 is a newly identified melanocyte differentiation antigen recognized by autologous cytotoxic T lymphocytes. Tyrosinase is one of the targets for cytotoxic T-cell recognition in melanoma patients. The function of gp100 is not known but it is reported to be a useful marker for melanocytes and melanomas. This cocktail of three markers is designed for extremely sensitive labeling of formalin-fixed, paraffin-embedded melanomas and other tumors showing melanocytic differentiation.
Content And Storage:
Store at 4C.
Isotype:
IgG1, IgG2a κ
Applications:
Immunohistochemistry (Paraffin)
Clone:
A103 + T311 + HMB45
Dilution:
Immunohistochemistry, Immunohistochemistry-Paraffin
Gene Alias:
MART1, MART-1, melan-A, MLANA
Host Species:
Mouse
Molecular Weight of Antigen:
__
Quantity:
7 mL
Research Discipline:
__
Gene ID (Entrez):
2315
Target Species:
Human
Form:
Purified
Antigen: MFG-E8
Classification: Monoclonal
Conjugate: Unconjugated
Formulation: 10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Gene Symbols: MFGE8
Immunogen: Human milk fat globule membrane preparation (Uniprot: Q08431)
Purification Method: Protein A or G purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: Recognizes a protein of 40-45kDa, identified as human milk fat globule membrane protein (HMFG). HMFG is present on normal human breast epithelial cells and cell lines derived from breast carcinomas, as well as to the outer surface of the human milk fat globule. HMFG is considered as a differentiation marker. It is useful as specific breast epithelial marker and can also provide a tool to study the role of the cell surface in normal and neoplastic mammary development.
Content And Storage: Store at 4C.
Isotype: IgG1 κ
Applications: Immunohistochemistry (Paraffin)
Clone: SPM291
Dilution: Immunohistochemistry-Paraffin
Gene Alias: BA46, Breast epithelial antigen BA46, EDIL1, hP47, HsT19888, lactadherin, medin, MFG1, MFG-E8, MFGM, Milk fat globule-EGF factor 8, milk fat globule-EGF factor 8 protein, O-acetyl disialoganglioside synthase, OAcGD3S, SED1, SPAG10, sperm associated antigen 10, sperm surface protein hP47
Host Species: Mouse
Molecular Weight of Antigen: 45 kDa
Quantity: 7 mL
Research Discipline: Cancer
Gene ID (Entrez): 4240
Target Species: Human
Form: Purified
Antigen:
MFG-E8
Classification:
Monoclonal
Conjugate:
Unconjugated
Formulation:
10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Gene Symbols:
MFGE8
Immunogen:
Human milk fat globule membrane preparation (Uniprot: Q08431)
Purification Method:
Protein A or G purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
Recognizes a protein of 40-45kDa, identified as human milk fat globule membrane protein (HMFG). HMFG is present on normal human breast epithelial cells and cell lines derived from breast carcinomas, as well as to the outer surface of the human milk fat globule. HMFG is considered as a differentiation marker. It is useful as specific breast epithelial marker and can also provide a tool to study the role of the cell surface in normal and neoplastic mammary development.
Content And Storage:
Store at 4C.
Isotype:
IgG1 κ
Applications:
Immunohistochemistry (Paraffin)
Clone:
SPM291
Dilution:
Immunohistochemistry-Paraffin
Gene Alias:
BA46, Breast epithelial antigen BA46, EDIL1, hP47, HsT19888, lactadherin, medin, MFG1, MFG-E8, MFGM, Milk fat globule-EGF factor 8, milk fat globule-EGF factor 8 protein, O-acetyl disialoganglioside synthase, OAcGD3S, SED1, SPAG10, sperm associated antigen 10, sperm surface protein hP47
Host Species:
Mouse
Molecular Weight of Antigen:
45 kDa
Quantity:
7 mL
Research Discipline:
Cancer
Gene ID (Entrez):
4240
Target Species:
Human
Form:
Purified