NBP248304
bcl-x Antibody (SPM337) - IHC-Prediluted, Novus Biologicals™
Manufacturer: Novus Biologicals
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | NBP248304-Each-of-1 | In Stock | ₹ 44,833.44 |
NBP248304 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,833.44
GST (18%): ₹ 8,070.019
Total Price: ₹ 52,903.459
Antigen
Bcl-xL
Classification
Monoclonal
Conjugate
Unconjugated
Formulation
10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Gene Symbols
BCL2L1
Immunogen
A synthetic peptide, aa 3-14 (Cys-QSNRELVVDFLS) of human Bcl-xL protein (Uniprot: Q07817)
Purification Method
Protein A or G purified
Regulatory Status
RUO
Primary or Secondary
Primary
Test Specificity
Recognizes a protein of 27kDa, identified as the Bcl-X protein. This monoclonal antibody shows no cross-reaction with Bcl-2 or Bax protein. Bcl-X has two isoforms, Bcl-XL (long), a 241 amino acid protein which suppresses cell death. And Bcl-XS (short), a 178 amino acid protein lacking a 63 amino acid domain which functions as a dominant inhibitor of Bcl-2. This monoclonal antibody reacts with both Bcl-XS and Bcl-XL proteins.
Content And Storage
Store at 4C.
Isotype
IgG2a κ
Applications
Immunohistochemistry (Paraffin)
Clone
SPM337
Dilution
Immunohistochemistry-Paraffin
Gene Alias
Apoptosis regulator Bcl-X, bcl2-L-1, BCL2-like 1, bcl-2-like protein 1, BCLXBCL2LBcl-X, bcl-xL, BCLXL, BCL-XL/S, bcl-xS, BCLXS, DKFZp781P2092
Host Species
Mouse
Molecular Weight of Antigen
27 kDa
Quantity
7 mL
Research Discipline
Apoptosis, Cancer, Tumor Suppressors
Gene ID (Entrez)
598
Target Species
Human, Mouse, Rat, Porcine
Form
Purified
Related Products
Description
- Bcl-xL Monoclonal specifically detects Bcl-xL in Human, Mouse, Rat, Porcine samples
- It is validated for Immunohistochemistry, Immunohistochemistry-Paraffin.
Compare Similar Items
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Antigen: Bcl-xL
Classification: Monoclonal
Conjugate: Unconjugated
Formulation: 10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Gene Symbols: BCL2L1
Immunogen: A synthetic peptide, aa 3-14 (Cys-QSNRELVVDFLS) of human Bcl-xL protein (Uniprot: Q07817)
Purification Method: Protein A or G purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: Recognizes a protein of 27kDa, identified as the Bcl-X protein. This monoclonal antibody shows no cross-reaction with Bcl-2 or Bax protein. Bcl-X has two isoforms, Bcl-XL (long), a 241 amino acid protein which suppresses cell death. And Bcl-XS (short), a 178 amino acid protein lacking a 63 amino acid domain which functions as a dominant inhibitor of Bcl-2. This monoclonal antibody reacts with both Bcl-XS and Bcl-XL proteins.
Content And Storage: Store at 4C.
Isotype: IgG2a κ
Applications: Immunohistochemistry (Paraffin)
Clone: SPM337
Dilution: Immunohistochemistry-Paraffin
Gene Alias: Apoptosis regulator Bcl-X, bcl2-L-1, BCL2-like 1, bcl-2-like protein 1, BCLXBCL2LBcl-X, bcl-xL, BCLXL, BCL-XL/S, bcl-xS, BCLXS, DKFZp781P2092
Host Species: Mouse
Molecular Weight of Antigen: 27 kDa
Quantity: 7 mL
Research Discipline: Apoptosis, Cancer, Tumor Suppressors
Gene ID (Entrez): 598
Target Species: Human, Mouse, Rat, Porcine
Form: Purified
Antigen:
Bcl-xL
Classification:
Monoclonal
Conjugate:
Unconjugated
Formulation:
10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Gene Symbols:
BCL2L1
Immunogen:
A synthetic peptide, aa 3-14 (Cys-QSNRELVVDFLS) of human Bcl-xL protein (Uniprot: Q07817)
Purification Method:
Protein A or G purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
Recognizes a protein of 27kDa, identified as the Bcl-X protein. This monoclonal antibody shows no cross-reaction with Bcl-2 or Bax protein. Bcl-X has two isoforms, Bcl-XL (long), a 241 amino acid protein which suppresses cell death. And Bcl-XS (short), a 178 amino acid protein lacking a 63 amino acid domain which functions as a dominant inhibitor of Bcl-2. This monoclonal antibody reacts with both Bcl-XS and Bcl-XL proteins.
Content And Storage:
Store at 4C.
Isotype:
IgG2a κ
Applications:
Immunohistochemistry (Paraffin)
Clone:
SPM337
Dilution:
Immunohistochemistry-Paraffin
Gene Alias:
Apoptosis regulator Bcl-X, bcl2-L-1, BCL2-like 1, bcl-2-like protein 1, BCLXBCL2LBcl-X, bcl-xL, BCLXL, BCL-XL/S, bcl-xS, BCLXS, DKFZp781P2092
Host Species:
Mouse
Molecular Weight of Antigen:
27 kDa
Quantity:
7 mL
Research Discipline:
Apoptosis, Cancer, Tumor Suppressors
Gene ID (Entrez):
598
Target Species:
Human, Mouse, Rat, Porcine
Form:
Purified
Antigen: Moesin
Classification: Monoclonal
Conjugate: Unconjugated
Formulation: 10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Gene Symbols: MSN
Immunogen: Recombinant full-length human Moesin protein (Uniprot: P26038 )
Purification Method: Protein A or G purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: Recognizes 78kDa moesin protein. Moesin, a member of the talin-4.1 superfamily, is a linking protein of the sub-membranous actin cytoskeleton. It is expressed in variable amounts in cells of different phenotypes such as macrophages, lymphocytes, fibroblastic, endothelial, epithelial, and neuronal cell lines but not in blood cells. The ERM proteins, ezrin, radixin, and moesin are involved in a variety of cellular functions, such as cell adhesion, migration, and the organization of cell surface structures, and are highly homologous, both in protein sequence and in functional activity, with merlin/schwannomin, a neurofibromatosis-2-associated tumor-suppressor protein. Cell lines of epithelial and mesothelial origin contain both moesin and radixin whereas cells of endothelial and lymphoid origin express moesin.
Content And Storage: Store at 4C.
Isotype: IgG1 κ
Applications: Immunohistochemistry, Immunohistochemistry (Paraffin), Immunoassay
Clone: MSN/492
Dilution: Immunohistochemistry, Immunohistochemistry-Paraffin, Knockout Validated
Gene Alias: Membrane-organizing extension spike protein, moesin
Host Species: Mouse
Molecular Weight of Antigen: 78 kDa
Quantity: 7 mL
Research Discipline: Cytoskeleton Markers, Stem Cell Markers
Gene ID (Entrez): 4478
Target Species: Human, Rat (Negative)
Form: Purified
Antigen:
Moesin
Classification:
Monoclonal
Conjugate:
Unconjugated
Formulation:
10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Gene Symbols:
MSN
Immunogen:
Recombinant full-length human Moesin protein (Uniprot: P26038 )
Purification Method:
Protein A or G purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
Recognizes 78kDa moesin protein. Moesin, a member of the talin-4.1 superfamily, is a linking protein of the sub-membranous actin cytoskeleton. It is expressed in variable amounts in cells of different phenotypes such as macrophages, lymphocytes, fibroblastic, endothelial, epithelial, and neuronal cell lines but not in blood cells. The ERM proteins, ezrin, radixin, and moesin are involved in a variety of cellular functions, such as cell adhesion, migration, and the organization of cell surface structures, and are highly homologous, both in protein sequence and in functional activity, with merlin/schwannomin, a neurofibromatosis-2-associated tumor-suppressor protein. Cell lines of epithelial and mesothelial origin contain both moesin and radixin whereas cells of endothelial and lymphoid origin express moesin.
Content And Storage:
Store at 4C.
Isotype:
IgG1 κ
Applications:
Immunohistochemistry, Immunohistochemistry (Paraffin), Immunoassay
Clone:
MSN/492
Dilution:
Immunohistochemistry, Immunohistochemistry-Paraffin, Knockout Validated
Gene Alias:
Membrane-organizing extension spike protein, moesin
Host Species:
Mouse
Molecular Weight of Antigen:
78 kDa
Quantity:
7 mL
Research Discipline:
Cytoskeleton Markers, Stem Cell Markers
Gene ID (Entrez):
4478
Target Species:
Human, Rat (Negative)
Form:
Purified
Antigen: Moesin
Classification: Monoclonal
Conjugate: Unconjugated
Formulation: 10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Gene Symbols: MSN
Immunogen: Recombinant full-length human Moesin protein (Uniprot: P26038)
Purification Method: Protein A or G purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: Recognizes 78kDa moesin protein. Moesin, a member of the talin-4.1 superfamily, is a linking protein of the sub-membranous actin cytoskeleton. It is expressed in variable amounts in cells of different phenotypes such as macrophages, lymphocytes, fibroblastic, endothelial, epithelial, and neuronal cell lines but not in blood cells. The ERM proteins, ezrin, radixin, and moesin are involved in a variety of cellular functions, such as cell adhesion, migration, and the organization of cell surface structures, and are highly homologous, both in protein sequence and in functional activity, with merlin/schwannomin, a neurofibromatosis-2-associated tumor-suppressor protein. Cell lines of epithelial and mesothelial origin contain both moesin and radixin whereas cells of endothelial and lymphoid origin express moesin.
Content And Storage: Store at 4C.
Isotype: IgG1 κ
Applications: Immunohistochemistry, Immunohistochemistry (Paraffin), Immunoassay
Clone: MSN/493
Dilution: Immunohistochemistry, Immunohistochemistry-Paraffin, Knockout Validated
Gene Alias: Membrane-organizing extension spike protein, moesin
Host Species: Mouse
Molecular Weight of Antigen: 78 kDa
Quantity: 7 mL
Research Discipline: Cytoskeleton Markers, Stem Cell Markers
Gene ID (Entrez): 4478
Target Species: Human, Rat (Negative)
Form: Purified
Antigen:
Moesin
Classification:
Monoclonal
Conjugate:
Unconjugated
Formulation:
10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Gene Symbols:
MSN
Immunogen:
Recombinant full-length human Moesin protein (Uniprot: P26038)
Purification Method:
Protein A or G purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
Recognizes 78kDa moesin protein. Moesin, a member of the talin-4.1 superfamily, is a linking protein of the sub-membranous actin cytoskeleton. It is expressed in variable amounts in cells of different phenotypes such as macrophages, lymphocytes, fibroblastic, endothelial, epithelial, and neuronal cell lines but not in blood cells. The ERM proteins, ezrin, radixin, and moesin are involved in a variety of cellular functions, such as cell adhesion, migration, and the organization of cell surface structures, and are highly homologous, both in protein sequence and in functional activity, with merlin/schwannomin, a neurofibromatosis-2-associated tumor-suppressor protein. Cell lines of epithelial and mesothelial origin contain both moesin and radixin whereas cells of endothelial and lymphoid origin express moesin.
Content And Storage:
Store at 4C.
Isotype:
IgG1 κ
Applications:
Immunohistochemistry, Immunohistochemistry (Paraffin), Immunoassay
Clone:
MSN/493
Dilution:
Immunohistochemistry, Immunohistochemistry-Paraffin, Knockout Validated
Gene Alias:
Membrane-organizing extension spike protein, moesin
Host Species:
Mouse
Molecular Weight of Antigen:
78 kDa
Quantity:
7 mL
Research Discipline:
Cytoskeleton Markers, Stem Cell Markers
Gene ID (Entrez):
4478
Target Species:
Human, Rat (Negative)
Form:
Purified
Antigen: ER beta/NR3A2
Classification: Monoclonal
Conjugate: Unconjugated
Formulation: 10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Gene Symbols: ESR2
Immunogen: C-terminus fragment of recombinant human ER beta/NR3A2 protein (Uniprot: Q92731)
Purification Method: Protein A or G purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: Estrogen receptors (ER) are members of the steroid/thyroid hormone receptor superfamily of ligand-activated transcription factors. Estrogen receptors, including ER-alpha and ER-beta, contain DNA binding and ligand binding domains and are critically involved in regulating the normal function of reproductive tissues. They are located in the nucleus, though some estrogen receptors associate with the cell surface membrane and can be rapidly activated by exposure of cells to estrogen. ER-alpha and ER-beta are differentially activated by various ligands. Receptor-ligand interactions trigger a cascade of events, including dissociation from heat shock proteins, receptor dimerization, phosphorylation and the association of the hormone activated receptor with specific regulatory elements in target genes. Evidence suggests that ER-alpha and ER-beta may be regulated by distinct mechanisms even though they share many functional characteristics.
Content And Storage: Store at 4C.
Isotype: IgG2a κ
Applications: Immunohistochemistry (Paraffin)
Clone: ESR2/686
Dilution: Immunohistochemistry-Paraffin
Gene Alias: Erb, ER-beta, ESR-BETA, ESTRB, estrogen receptor 2 (ER beta), estrogen receptor beta, estrogen receptor beta 4, NR3A2ESRB, Nuclear receptor subfamily 3 group A member 2
Host Species: Mouse
Molecular Weight of Antigen: __
Quantity: 7 mL
Research Discipline: Breast Cancer, Cancer, Cell Biology, Cell Cycle and Replication, Dendritic Cell Markers, GPCR, Neuroscience, Signal Transduction, Transcription Factors and Regulators
Gene ID (Entrez): 2100
Target Species: Human
Form: Purified
Antigen:
ER beta/NR3A2
Classification:
Monoclonal
Conjugate:
Unconjugated
Formulation:
10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Gene Symbols:
ESR2
Immunogen:
C-terminus fragment of recombinant human ER beta/NR3A2 protein (Uniprot: Q92731)
Purification Method:
Protein A or G purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
Estrogen receptors (ER) are members of the steroid/thyroid hormone receptor superfamily of ligand-activated transcription factors. Estrogen receptors, including ER-alpha and ER-beta, contain DNA binding and ligand binding domains and are critically involved in regulating the normal function of reproductive tissues. They are located in the nucleus, though some estrogen receptors associate with the cell surface membrane and can be rapidly activated by exposure of cells to estrogen. ER-alpha and ER-beta are differentially activated by various ligands. Receptor-ligand interactions trigger a cascade of events, including dissociation from heat shock proteins, receptor dimerization, phosphorylation and the association of the hormone activated receptor with specific regulatory elements in target genes. Evidence suggests that ER-alpha and ER-beta may be regulated by distinct mechanisms even though they share many functional characteristics.
Content And Storage:
Store at 4C.
Isotype:
IgG2a κ
Applications:
Immunohistochemistry (Paraffin)
Clone:
ESR2/686
Dilution:
Immunohistochemistry-Paraffin
Gene Alias:
Erb, ER-beta, ESR-BETA, ESTRB, estrogen receptor 2 (ER beta), estrogen receptor beta, estrogen receptor beta 4, NR3A2ESRB, Nuclear receptor subfamily 3 group A member 2
Host Species:
Mouse
Molecular Weight of Antigen:
__
Quantity:
7 mL
Research Discipline:
Breast Cancer, Cancer, Cell Biology, Cell Cycle and Replication, Dendritic Cell Markers, GPCR, Neuroscience, Signal Transduction, Transcription Factors and Regulators
Gene ID (Entrez):
2100
Target Species:
Human
Form:
Purified