NBP248241
IgM Heavy Chain Antibody (Cocktail) - IHC-Prediluted, Novus Biologicals™
Manufacturer: Novus Biologicals
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | NBP248241-Each-of-1 | In Stock | ₹ 44,833.44 |
NBP248241 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,833.44
GST (18%): ₹ 8,070.019
Total Price: ₹ 52,903.459
Antigen
IgM Heavy Chain
Classification
Monoclonal
Conjugate
Unconjugated
Formulation
10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Gene Symbols
IGHM
Immunogen
Recombinant heavy chain of human IgM (IM260 & IM373); Heavy chain of human IgM (ICO-30)
Quantity
7 mL
Primary or Secondary
Primary
Test Specificity
Recognizes a protein of 75kDa, identified as mu heavy chain of human immunoglobulins. It does not cross-react with alpha (IgA), gamma (IgG), epsilon (IgE), or delta (IgD), heavy chains, T-cells, monocytes, granulocytes, or erythrocytes. This monoclonal antibody is useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkins lymphomas. The most common feature of these malignancies is the restricted expression of a single heavy chain class. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is clonal and therefore malignant.
Content And Storage
Store at 4C.
Isotype
IgG1 κ, IgG2b κ
Applications
Immunohistochemistry (Paraffin)
Clone
Cocktail
Dilution
Immunohistochemistry-Paraffin
Gene Alias
Constant region of heavy chain of IgM, Ig Mu Chain C Region BOT Ig Mu Chain C Region GAL Ig Mu Chain C Region OU immunoglobulin heavy constant mu, Immunoglobulin mu chain
Host Species
Mouse
Purification Method
Protein A or G purified
Regulatory Status
RUO
Gene ID (Entrez)
3507
Target Species
Human
Form
Purified
Related Products
Description
- IgM Heavy Chain Monoclonal specifically detects IgM Heavy Chain in Human samples
- It is validated for Immunohistochemistry, Immunohistochemistry-Paraffin.
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Antigen: IgM Heavy Chain
Classification: Monoclonal
Conjugate: Unconjugated
Formulation: 10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Gene Symbols: IGHM
Immunogen: Recombinant heavy chain of human IgM (IM260 & IM373); Heavy chain of human IgM (ICO-30)
Quantity: 7 mL
Primary or Secondary: Primary
Test Specificity: Recognizes a protein of 75kDa, identified as mu heavy chain of human immunoglobulins. It does not cross-react with alpha (IgA), gamma (IgG), epsilon (IgE), or delta (IgD), heavy chains, T-cells, monocytes, granulocytes, or erythrocytes. This monoclonal antibody is useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkins lymphomas. The most common feature of these malignancies is the restricted expression of a single heavy chain class. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is clonal and therefore malignant.
Content And Storage: Store at 4C.
Isotype: IgG1 κ, IgG2b κ
Applications: Immunohistochemistry (Paraffin)
Clone: Cocktail
Dilution: Immunohistochemistry-Paraffin
Gene Alias: Constant region of heavy chain of IgM, Ig Mu Chain C Region BOT Ig Mu Chain C Region GAL Ig Mu Chain C Region OU immunoglobulin heavy constant mu, Immunoglobulin mu chain
Host Species: Mouse
Purification Method: Protein A or G purified
Regulatory Status: RUO
Gene ID (Entrez): 3507
Target Species: Human
Form: Purified
Antigen:
IgM Heavy Chain
Classification:
Monoclonal
Conjugate:
Unconjugated
Formulation:
10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Gene Symbols:
IGHM
Immunogen:
Recombinant heavy chain of human IgM (IM260 & IM373); Heavy chain of human IgM (ICO-30)
Quantity:
7 mL
Primary or Secondary:
Primary
Test Specificity:
Recognizes a protein of 75kDa, identified as mu heavy chain of human immunoglobulins. It does not cross-react with alpha (IgA), gamma (IgG), epsilon (IgE), or delta (IgD), heavy chains, T-cells, monocytes, granulocytes, or erythrocytes. This monoclonal antibody is useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkins lymphomas. The most common feature of these malignancies is the restricted expression of a single heavy chain class. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is clonal and therefore malignant.
Content And Storage:
Store at 4C.
Isotype:
IgG1 κ, IgG2b κ
Applications:
Immunohistochemistry (Paraffin)
Clone:
Cocktail
Dilution:
Immunohistochemistry-Paraffin
Gene Alias:
Constant region of heavy chain of IgM, Ig Mu Chain C Region BOT Ig Mu Chain C Region GAL Ig Mu Chain C Region OU immunoglobulin heavy constant mu, Immunoglobulin mu chain
Host Species:
Mouse
Purification Method:
Protein A or G purified
Regulatory Status:
RUO
Gene ID (Entrez):
3507
Target Species:
Human
Form:
Purified
Antigen: Insulin
Classification: Monoclonal
Conjugate: Unconjugated
Formulation: 10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Gene Symbols: INS
Immunogen: Recombinant Insulin protein (Uniprot: P01308)
Quantity: 7 mL
Primary or Secondary: Primary
Test Specificity: Recognizes a polypeptide which is identified as insulin, a 51-amino acid polypeptide composed of A and B chains connected through the C-peptide. Proinsulin, which has very little biological activity, is cleaved by proteases within its cell of origin into the insulin molecule and the C-terminal basic residue. Insulin enhances membrane transport of glucose, amino acids, and certain ions. It also promotes glycogen storage, formation of triglycerides, and synthesis of proteins and nucleic acids. Deficiency of insulin results in diabetes mellitus. The main storage site for insulin is the pancreatic islets. Antibodies to insulin are important as beta-cell and insulinoma marker.
Content And Storage: Store at 4C.
Isotype: IgG1 κ
Applications: Immunohistochemistry (Paraffin)
Clone: IRDN/794
Dilution: Immunohistochemistry-Paraffin
Gene Alias: IDDM2, ILPR, insulin, IRDN, MODY10, proinsulin
Host Species: Mouse
Purification Method: Protein A or G purified
Regulatory Status: RUO
Gene ID (Entrez): 3630
Target Species: Human, Mouse, Rat, Porcine, Primate
Form: Purified
Antigen:
Insulin
Classification:
Monoclonal
Conjugate:
Unconjugated
Formulation:
10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Gene Symbols:
INS
Immunogen:
Recombinant Insulin protein (Uniprot: P01308)
Quantity:
7 mL
Primary or Secondary:
Primary
Test Specificity:
Recognizes a polypeptide which is identified as insulin, a 51-amino acid polypeptide composed of A and B chains connected through the C-peptide. Proinsulin, which has very little biological activity, is cleaved by proteases within its cell of origin into the insulin molecule and the C-terminal basic residue. Insulin enhances membrane transport of glucose, amino acids, and certain ions. It also promotes glycogen storage, formation of triglycerides, and synthesis of proteins and nucleic acids. Deficiency of insulin results in diabetes mellitus. The main storage site for insulin is the pancreatic islets. Antibodies to insulin are important as beta-cell and insulinoma marker.
Content And Storage:
Store at 4C.
Isotype:
IgG1 κ
Applications:
Immunohistochemistry (Paraffin)
Clone:
IRDN/794
Dilution:
Immunohistochemistry-Paraffin
Gene Alias:
IDDM2, ILPR, insulin, IRDN, MODY10, proinsulin
Host Species:
Mouse
Purification Method:
Protein A or G purified
Regulatory Status:
RUO
Gene ID (Entrez):
3630
Target Species:
Human, Mouse, Rat, Porcine, Primate
Form:
Purified
Antigen: Endorepellin/Perlecan/Heparan Sulfate Proteoglycan
Classification: Monoclonal
Conjugate: Unconjugated
Formulation: 10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Gene Symbols: HSPG2
Immunogen: Murine EHS laminin preparation
Quantity: 7 mL
Primary or Secondary: Primary
Test Specificity: This monoclonal antibody specifically precipitates heterogeneous material of high MW, identified as perlecan, a major heparan-sulfate proteoglycan (HSPG) within all basement membranes and cell surfaces. It does not cross-react with laminin, fibronectin, or dermatran sulfate proteoglycan. Because of perlecans strategic location and ability to store and protect growth factors, it has been strongly implicated in the control of tumor cell growth and metastatic behavior. Perlecan possesses angiogenic and growth-promoting attributes primarily by acting as a co-receptor for basic fibroblast growth factor (FGF-2). Suppression of perlecan causes substantial inhibition of neoplastic growth and neovascularization. Thus, perlecan is a potent inducer of neoplasm growth and angiogenesis in vivo and therapeutic interventions targeting this key modulator of tumor progression may improve neoplastic treatment.
Content And Storage: Store at 4C.
Isotype: IgG2a κ
Applications: Immunohistochemistry (Paraffin)
Clone: SPM255
Dilution: Immunohistochemistry-Paraffin
Gene Alias: basement membrane-specific heparan sulfate proteoglycan core protein, endorepellin (domain V region), heparan sulfate proteoglycan 2, HSPG, perlecan, perlecan proteoglycan, PLCSchwartz-Jampel syndrome 1 (chondrodystrophic myotonia), PRCAN, SJA, SJS, SJS1
Host Species: Rat
Purification Method: Protein A or G purified
Regulatory Status: RUO
Gene ID (Entrez): 3339
Target Species: Human, Mouse, Porcine, Fish, Primate, Monkey
Form: Purified
Antigen:
Endorepellin/Perlecan/Heparan Sulfate Proteoglycan
Classification:
Monoclonal
Conjugate:
Unconjugated
Formulation:
10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Gene Symbols:
HSPG2
Immunogen:
Murine EHS laminin preparation
Quantity:
7 mL
Primary or Secondary:
Primary
Test Specificity:
This monoclonal antibody specifically precipitates heterogeneous material of high MW, identified as perlecan, a major heparan-sulfate proteoglycan (HSPG) within all basement membranes and cell surfaces. It does not cross-react with laminin, fibronectin, or dermatran sulfate proteoglycan. Because of perlecans strategic location and ability to store and protect growth factors, it has been strongly implicated in the control of tumor cell growth and metastatic behavior. Perlecan possesses angiogenic and growth-promoting attributes primarily by acting as a co-receptor for basic fibroblast growth factor (FGF-2). Suppression of perlecan causes substantial inhibition of neoplastic growth and neovascularization. Thus, perlecan is a potent inducer of neoplasm growth and angiogenesis in vivo and therapeutic interventions targeting this key modulator of tumor progression may improve neoplastic treatment.
Content And Storage:
Store at 4C.
Isotype:
IgG2a κ
Applications:
Immunohistochemistry (Paraffin)
Clone:
SPM255
Dilution:
Immunohistochemistry-Paraffin
Gene Alias:
basement membrane-specific heparan sulfate proteoglycan core protein, endorepellin (domain V region), heparan sulfate proteoglycan 2, HSPG, perlecan, perlecan proteoglycan, PLCSchwartz-Jampel syndrome 1 (chondrodystrophic myotonia), PRCAN, SJA, SJS, SJS1
Host Species:
Rat
Purification Method:
Protein A or G purified
Regulatory Status:
RUO
Gene ID (Entrez):
3339
Target Species:
Human, Mouse, Porcine, Fish, Primate, Monkey
Form:
Purified
Antigen: Pax6
Classification: Monoclonal
Conjugate: Unconjugated
Formulation: 10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Gene Symbols: PAX6
Immunogen: Recombinant fragment (N-terminus; aa 1-300) of human Pax6 protein (Uniprot: P26367)
Quantity: 7 mL
Primary or Secondary: Primary
Test Specificity: Pax genes contain paired domains with strong homology to genes in Drosophila, which are involved in programming early development. Lesions in the Pax-6 gene account for most cases of aniridia, a congenital malformation of the eye, chiefly characterized by iris hypoplasia, which can cause blindness. Pax-6 is involved in other anterior segment malformations besides aniridia, such as Peters anomaly, a major error in the embryonic development of the eye with corneal clouding with variable iridolenticulocorneal adhesions. The Pax-6 gene encodes a transcriptional regulator that recognizes target genes through its paired-type DNA-binding domain. The paired domain is composed of two distinct DNA-binding subdomains, the amino-terminal subdomain and the carboxy-terminal subdomain, which bind respective consensus DNA sequences. The human Pax-6 gene produces two alternatively spliced isoforms that have the distinct structure of the paired domain.
Content And Storage: Store at 4C.
Isotype: IgG1 κ
Applications: Immunohistochemistry (Paraffin)
Clone: SPM612
Dilution: Immunohistochemistry-Paraffin
Gene Alias: keratitis), MGC17209, Oculorhombin, paired box 6, paired box protein Pax-6
Host Species: Mouse
Purification Method: Protein A or G purified
Regulatory Status: RUO
Gene ID (Entrez): 5080
Target Species: Human
Form: Purified
Antigen:
Pax6
Classification:
Monoclonal
Conjugate:
Unconjugated
Formulation:
10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Gene Symbols:
PAX6
Immunogen:
Recombinant fragment (N-terminus; aa 1-300) of human Pax6 protein (Uniprot: P26367)
Quantity:
7 mL
Primary or Secondary:
Primary
Test Specificity:
Pax genes contain paired domains with strong homology to genes in Drosophila, which are involved in programming early development. Lesions in the Pax-6 gene account for most cases of aniridia, a congenital malformation of the eye, chiefly characterized by iris hypoplasia, which can cause blindness. Pax-6 is involved in other anterior segment malformations besides aniridia, such as Peters anomaly, a major error in the embryonic development of the eye with corneal clouding with variable iridolenticulocorneal adhesions. The Pax-6 gene encodes a transcriptional regulator that recognizes target genes through its paired-type DNA-binding domain. The paired domain is composed of two distinct DNA-binding subdomains, the amino-terminal subdomain and the carboxy-terminal subdomain, which bind respective consensus DNA sequences. The human Pax-6 gene produces two alternatively spliced isoforms that have the distinct structure of the paired domain.
Content And Storage:
Store at 4C.
Isotype:
IgG1 κ
Applications:
Immunohistochemistry (Paraffin)
Clone:
SPM612
Dilution:
Immunohistochemistry-Paraffin
Gene Alias:
keratitis), MGC17209, Oculorhombin, paired box 6, paired box protein Pax-6
Host Species:
Mouse
Purification Method:
Protein A or G purified
Regulatory Status:
RUO
Gene ID (Entrez):
5080
Target Species:
Human
Form:
Purified