NBP248057
Granulocyte Marker Antibody (SPM250) - IHC-Prediluted, Novus Biologicals™
Manufacturer: Novus Biologicals
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | NBP248057-Each-of-1 | In Stock | ₹ 44,833.44 |
NBP248057 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,833.44
GST (18%): ₹ 8,070.019
Total Price: ₹ 52,903.459
Antigen
Granulocyte Marker
Classification
Monoclonal
Conjugate
Unconjugated
Formulation
10 mM PBS with 0.05% BSA with 0.05% Sodium Azide
Immunogen
Nuclei from pokeweed mitogen stimulated human peripheral blood lymphocytes.
Quantity
7 mL
Primary or Secondary
Primary
Target Species
Human, Primate
Form
Purified
Applications
Immunohistochemistry (Paraffin)
Clone
SPM250
Dilution
Immunohistochemistry-Paraffin
Host Species
Mouse
Purification Method
Protein A or G purified
Regulatory Status
RUO
Test Specificity
Recognizes an unidentified antigen in the cytoplasm of mature granulocytes. It shows no reactivity with any other cell type in human tissues. Markers of myeloid cells are useful in the identification of different levels of cellular differentiation. monoclonal antibody BM-2 reacts with early precursor and mature forms of human myeloid cells. This monoclonal antibody is useful for the detection of myeloid leukemias and granulocytic sarcomas. It can be used as a marker of granulocytes in normal tissues or inflammatory processes.
Content And Storage
Store at 4C.
Isotype
IgG1 κ
Related Products
Description
- Granulocyte Marker Monoclonal specifically detects Granulocyte Marker in Human, Rhesus Macaque samples
- It is validated for Immunohistochemistry, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen.
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Antigen: Granulocyte Marker
Classification: Monoclonal
Conjugate: Unconjugated
Formulation: 10 mM PBS with 0.05% BSA with 0.05% Sodium Azide
Immunogen: Nuclei from pokeweed mitogen stimulated human peripheral blood lymphocytes.
Quantity: 7 mL
Primary or Secondary: Primary
Target Species: Human, Primate
Form: Purified
Applications: Immunohistochemistry (Paraffin)
Clone: SPM250
Dilution: Immunohistochemistry-Paraffin
Host Species: Mouse
Purification Method: Protein A or G purified
Regulatory Status: RUO
Test Specificity: Recognizes an unidentified antigen in the cytoplasm of mature granulocytes. It shows no reactivity with any other cell type in human tissues. Markers of myeloid cells are useful in the identification of different levels of cellular differentiation. monoclonal antibody BM-2 reacts with early precursor and mature forms of human myeloid cells. This monoclonal antibody is useful for the detection of myeloid leukemias and granulocytic sarcomas. It can be used as a marker of granulocytes in normal tissues or inflammatory processes.
Content And Storage: Store at 4C.
Isotype: IgG1 κ
Antigen:
Granulocyte Marker
Classification:
Monoclonal
Conjugate:
Unconjugated
Formulation:
10 mM PBS with 0.05% BSA with 0.05% Sodium Azide
Immunogen:
Nuclei from pokeweed mitogen stimulated human peripheral blood lymphocytes.
Quantity:
7 mL
Primary or Secondary:
Primary
Target Species:
Human, Primate
Form:
Purified
Applications:
Immunohistochemistry (Paraffin)
Clone:
SPM250
Dilution:
Immunohistochemistry-Paraffin
Host Species:
Mouse
Purification Method:
Protein A or G purified
Regulatory Status:
RUO
Test Specificity:
Recognizes an unidentified antigen in the cytoplasm of mature granulocytes. It shows no reactivity with any other cell type in human tissues. Markers of myeloid cells are useful in the identification of different levels of cellular differentiation. monoclonal antibody BM-2 reacts with early precursor and mature forms of human myeloid cells. This monoclonal antibody is useful for the detection of myeloid leukemias and granulocytic sarcomas. It can be used as a marker of granulocytes in normal tissues or inflammatory processes.
Content And Storage:
Store at 4C.
Isotype:
IgG1 κ
Antigen: TOX3
Classification: Monoclonal
Conjugate: Unconjugated
Formulation: 1 mM PBS with 0.05% BSA with 0.05% Sodium Azide
Immunogen: Recombinant fragment of human TOX3 protein (around aa 251-389) (Exact sequence is proprietary) (Uniprot: O15405)
Quantity: 7 mL
Primary or Secondary: Primary
Target Species: Human
Form: Purified
Applications: Immunohistochemistry (Paraffin)
Clone: TOX3/1123
Dilution: Immunohistochemistry-Paraffin
Host Species: Mouse
Purification Method: Protein A or G purified
Regulatory Status: RUO
Test Specificity: It recognizes a 63kDa protein, which is identified as TOX3. It contains a high mobility group (HMG)-box, which regulates Ca2+-dependent transcription in neurons through interaction with the cAMP-response-element-binding protein (CREB). TOX3 appears to be associated with breast cancer susceptibility and is expressed downstream of a cytoprotective cascade together with CITED1, a transcriptional regulator that does not bind directly to DNA. TOX3 is predominantly expressed in the brain and forms homodimers. TOX3 overexpression protects neuronal cells from cell death caused by endoplasmic reticulum stress or BAX overexpression through the induction of anti-apoptotic transcripts and repression of pro-apoptotic transcripts.
Content And Storage: Store at 4C.
Isotype: IgG2b κ
Antigen:
TOX3
Classification:
Monoclonal
Conjugate:
Unconjugated
Formulation:
1 mM PBS with 0.05% BSA with 0.05% Sodium Azide
Immunogen:
Recombinant fragment of human TOX3 protein (around aa 251-389) (Exact sequence is proprietary) (Uniprot: O15405)
Quantity:
7 mL
Primary or Secondary:
Primary
Target Species:
Human
Form:
Purified
Applications:
Immunohistochemistry (Paraffin)
Clone:
TOX3/1123
Dilution:
Immunohistochemistry-Paraffin
Host Species:
Mouse
Purification Method:
Protein A or G purified
Regulatory Status:
RUO
Test Specificity:
It recognizes a 63kDa protein, which is identified as TOX3. It contains a high mobility group (HMG)-box, which regulates Ca2+-dependent transcription in neurons through interaction with the cAMP-response-element-binding protein (CREB). TOX3 appears to be associated with breast cancer susceptibility and is expressed downstream of a cytoprotective cascade together with CITED1, a transcriptional regulator that does not bind directly to DNA. TOX3 is predominantly expressed in the brain and forms homodimers. TOX3 overexpression protects neuronal cells from cell death caused by endoplasmic reticulum stress or BAX overexpression through the induction of anti-apoptotic transcripts and repression of pro-apoptotic transcripts.
Content And Storage:
Store at 4C.
Isotype:
IgG2b κ
Antigen: ABO, Blood Group A Antigen
Classification: Monoclonal
Conjugate: Unconjugated
Formulation: 10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Immunogen: Mixture of erythrocytes of group B and glycoprotein fraction isolated from saliva of secretors with blood group B
Quantity: 7 mL
Primary or Secondary: Primary
Target Species: Human
Form: Purified
Applications: Immunohistochemistry (Paraffin)
Clone: HEB-20
Dilution: Immunohistochemistry-Paraffin
Host Species: Mouse
Purification Method: Protein L purified
Regulatory Status: RUO
Test Specificity: The antibody HEB-20 reacts with human blood group B. The specificity of the antibody HEB-20 was confirmed by comparison of specificity and reactivity to standard reagent using 5.000 samples of blood. The monoclonal antibody HEB-20 shows specific staining of erythrocytes and vascular epithelium of blood group B controls and no staining in group A controls. This monoclonal antibody is applicable for tissue staining in tumor patients with blood groups B and AB. Blood group antigens are generally defined as molecules formed by sequential addition of saccharides to the carbohydrate side chains of lipids and proteins detected on erythrocytes and certain epithelial cells. The A, B and H antigens are reported to undergo modulation during malignant cellular transformation. Blood group related antigens represent a group of carbohydrate determinants carried on both glycolipids and glycoproteins. They are usually mucin type, and are detected on erythrocytes, certain epithelial cells, and in secretions of certain individuals. Sixteen genetically and biosynthetically distinct but inter related specificities belong to this group of antigens, including A, B, H, Lewis A, Lewis B, Lewis X, Lewis Y, and precursor type 1 chain antigens.
Content And Storage: Store at 4C.
Isotype: IgG1 κ
Antigen:
ABO, Blood Group A Antigen
Classification:
Monoclonal
Conjugate:
Unconjugated
Formulation:
10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Immunogen:
Mixture of erythrocytes of group B and glycoprotein fraction isolated from saliva of secretors with blood group B
Quantity:
7 mL
Primary or Secondary:
Primary
Target Species:
Human
Form:
Purified
Applications:
Immunohistochemistry (Paraffin)
Clone:
HEB-20
Dilution:
Immunohistochemistry-Paraffin
Host Species:
Mouse
Purification Method:
Protein L purified
Regulatory Status:
RUO
Test Specificity:
The antibody HEB-20 reacts with human blood group B. The specificity of the antibody HEB-20 was confirmed by comparison of specificity and reactivity to standard reagent using 5.000 samples of blood. The monoclonal antibody HEB-20 shows specific staining of erythrocytes and vascular epithelium of blood group B controls and no staining in group A controls. This monoclonal antibody is applicable for tissue staining in tumor patients with blood groups B and AB. Blood group antigens are generally defined as molecules formed by sequential addition of saccharides to the carbohydrate side chains of lipids and proteins detected on erythrocytes and certain epithelial cells. The A, B and H antigens are reported to undergo modulation during malignant cellular transformation. Blood group related antigens represent a group of carbohydrate determinants carried on both glycolipids and glycoproteins. They are usually mucin type, and are detected on erythrocytes, certain epithelial cells, and in secretions of certain individuals. Sixteen genetically and biosynthetically distinct but inter related specificities belong to this group of antigens, including A, B, H, Lewis A, Lewis B, Lewis X, Lewis Y, and precursor type 1 chain antigens.
Content And Storage:
Store at 4C.
Isotype:
IgG1 κ
Antigen: Chromogranin A
Classification: Monoclonal
Conjugate: Unconjugated
Formulation: 10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Immunogen: Recombinant human Chromogranin A protein (Uniprot: P10645)
Quantity: 7 mL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat, Porcine, Monkey
Form: Purified
Applications: Immunohistochemistry (Paraffin)
Clone: CGA/413 + CHGA/777 + CHGA/798
Dilution: Immunohistochemistry-Paraffin
Host Species: Mouse
Purification Method: Protein A or G purified
Regulatory Status: RUO
Test Specificity: Chromogranin A is present in neuroendocrine cells throughout the body, including the neuroendocrine cells of the large and small intestine, adrenal medulla and pancreatic islets. It is an excellent marker for carcinoid tumors, pheochromocytomas, paragangliomas, and other neuroendocrine tumors. Co-expression of chromogranin A and neuron specific enolase (NSE) is common in neuroendocrine neoplasms. Reportedly, co-expression of certain keratins and chromogranin indicates neuroendocrine lineage. The presence of strong anti-chromogranin staining and absence of anti-keratin staining should raise the possibility of paraganglioma. The co-expression of chromogranin and NSE is typical of neuroendocrine neoplasms. Most pituitary adenomas and prolactinomas readily express chromogranin.
Content And Storage: Store at 4C.
Isotype: IgG2b κ
Antigen:
Chromogranin A
Classification:
Monoclonal
Conjugate:
Unconjugated
Formulation:
10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Immunogen:
Recombinant human Chromogranin A protein (Uniprot: P10645)
Quantity:
7 mL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat, Porcine, Monkey
Form:
Purified
Applications:
Immunohistochemistry (Paraffin)
Clone:
CGA/413 + CHGA/777 + CHGA/798
Dilution:
Immunohistochemistry-Paraffin
Host Species:
Mouse
Purification Method:
Protein A or G purified
Regulatory Status:
RUO
Test Specificity:
Chromogranin A is present in neuroendocrine cells throughout the body, including the neuroendocrine cells of the large and small intestine, adrenal medulla and pancreatic islets. It is an excellent marker for carcinoid tumors, pheochromocytomas, paragangliomas, and other neuroendocrine tumors. Co-expression of chromogranin A and neuron specific enolase (NSE) is common in neuroendocrine neoplasms. Reportedly, co-expression of certain keratins and chromogranin indicates neuroendocrine lineage. The presence of strong anti-chromogranin staining and absence of anti-keratin staining should raise the possibility of paraganglioma. The co-expression of chromogranin and NSE is typical of neuroendocrine neoplasms. Most pituitary adenomas and prolactinomas readily express chromogranin.
Content And Storage:
Store at 4C.
Isotype:
IgG2b κ