NBP248059
TOX3 Antibody (TOX3/1123) - IHC-Prediluted, Novus Biologicals™
Manufacturer: Novus Biologicals
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | NBP248059-Each-of-1 | In Stock | ₹ 44,833.44 |
NBP248059 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,833.44
GST (18%): ₹ 8,070.019
Total Price: ₹ 52,903.459
Antigen
TOX3
Classification
Monoclonal
Conjugate
Unconjugated
Formulation
1 mM PBS with 0.05% BSA with 0.05% Sodium Azide
Gene Symbols
TOX3
Immunogen
Recombinant fragment of human TOX3 protein (around aa 251-389) (Exact sequence is proprietary) (Uniprot: O15405)
Purification Method
Protein A or G purified
Regulatory Status
RUO
Gene ID (Entrez)
27324
Target Species
Human
Form
Purified
Applications
Immunohistochemistry (Paraffin)
Clone
TOX3/1123
Dilution
Immunohistochemistry-Paraffin
Gene Alias
CAG trinucleotide repeat-containing gene F9 protein, CAGF9trinucleotide repeat containing 9, TNRC9, TOX high mobility group box family member 3, Trinucleotide repeat-containing gene 9 protein
Host Species
Mouse
Molecular Weight of Antigen
63 kDa
Quantity
7 mL
Primary or Secondary
Primary
Test Specificity
It recognizes a 63kDa protein, which is identified as TOX3. It contains a high mobility group (HMG)-box, which regulates Ca2+-dependent transcription in neurons through interaction with the cAMP-response-element-binding protein (CREB). TOX3 appears to be associated with breast cancer susceptibility and is expressed downstream of a cytoprotective cascade together with CITED1, a transcriptional regulator that does not bind directly to DNA. TOX3 is predominantly expressed in the brain and forms homodimers. TOX3 overexpression protects neuronal cells from cell death caused by endoplasmic reticulum stress or BAX overexpression through the induction of anti-apoptotic transcripts and repression of pro-apoptotic transcripts.
Content And Storage
Store at 4C.
Isotype
IgG2b κ
Related Products
Description
- TOX3 Monoclonal specifically detects TOX3 in Human, Chicken samples
- It is validated for Immunohistochemistry, Immunohistochemistry-Paraffin.
Compare Similar Items
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Antigen: TOX3
Classification: Monoclonal
Conjugate: Unconjugated
Formulation: 1 mM PBS with 0.05% BSA with 0.05% Sodium Azide
Gene Symbols: TOX3
Immunogen: Recombinant fragment of human TOX3 protein (around aa 251-389) (Exact sequence is proprietary) (Uniprot: O15405)
Purification Method: Protein A or G purified
Regulatory Status: RUO
Gene ID (Entrez): 27324
Target Species: Human
Form: Purified
Applications: Immunohistochemistry (Paraffin)
Clone: TOX3/1123
Dilution: Immunohistochemistry-Paraffin
Gene Alias: CAG trinucleotide repeat-containing gene F9 protein, CAGF9trinucleotide repeat containing 9, TNRC9, TOX high mobility group box family member 3, Trinucleotide repeat-containing gene 9 protein
Host Species: Mouse
Molecular Weight of Antigen: 63 kDa
Quantity: 7 mL
Primary or Secondary: Primary
Test Specificity: It recognizes a 63kDa protein, which is identified as TOX3. It contains a high mobility group (HMG)-box, which regulates Ca2+-dependent transcription in neurons through interaction with the cAMP-response-element-binding protein (CREB). TOX3 appears to be associated with breast cancer susceptibility and is expressed downstream of a cytoprotective cascade together with CITED1, a transcriptional regulator that does not bind directly to DNA. TOX3 is predominantly expressed in the brain and forms homodimers. TOX3 overexpression protects neuronal cells from cell death caused by endoplasmic reticulum stress or BAX overexpression through the induction of anti-apoptotic transcripts and repression of pro-apoptotic transcripts.
Content And Storage: Store at 4C.
Isotype: IgG2b κ
Antigen:
TOX3
Classification:
Monoclonal
Conjugate:
Unconjugated
Formulation:
1 mM PBS with 0.05% BSA with 0.05% Sodium Azide
Gene Symbols:
TOX3
Immunogen:
Recombinant fragment of human TOX3 protein (around aa 251-389) (Exact sequence is proprietary) (Uniprot: O15405)
Purification Method:
Protein A or G purified
Regulatory Status:
RUO
Gene ID (Entrez):
27324
Target Species:
Human
Form:
Purified
Applications:
Immunohistochemistry (Paraffin)
Clone:
TOX3/1123
Dilution:
Immunohistochemistry-Paraffin
Gene Alias:
CAG trinucleotide repeat-containing gene F9 protein, CAGF9trinucleotide repeat containing 9, TNRC9, TOX high mobility group box family member 3, Trinucleotide repeat-containing gene 9 protein
Host Species:
Mouse
Molecular Weight of Antigen:
63 kDa
Quantity:
7 mL
Primary or Secondary:
Primary
Test Specificity:
It recognizes a 63kDa protein, which is identified as TOX3. It contains a high mobility group (HMG)-box, which regulates Ca2+-dependent transcription in neurons through interaction with the cAMP-response-element-binding protein (CREB). TOX3 appears to be associated with breast cancer susceptibility and is expressed downstream of a cytoprotective cascade together with CITED1, a transcriptional regulator that does not bind directly to DNA. TOX3 is predominantly expressed in the brain and forms homodimers. TOX3 overexpression protects neuronal cells from cell death caused by endoplasmic reticulum stress or BAX overexpression through the induction of anti-apoptotic transcripts and repression of pro-apoptotic transcripts.
Content And Storage:
Store at 4C.
Isotype:
IgG2b κ
Antigen: ABO, Blood Group A Antigen
Classification: Monoclonal
Conjugate: Unconjugated
Formulation: 10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Gene Symbols: ABO
Immunogen: Mixture of erythrocytes of group B and glycoprotein fraction isolated from saliva of secretors with blood group B
Purification Method: Protein L purified
Regulatory Status: RUO
Gene ID (Entrez): 28
Target Species: Human
Form: Purified
Applications: Immunohistochemistry (Paraffin)
Clone: HEB-20
Dilution: Immunohistochemistry-Paraffin
Gene Alias: A transferase, A3GALNT, A3GALT1, ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase;transferase B, alpha 1-3-galactosyltransferase), ABO glycosyltransferase, B transferase, B(A) alpha-1,3-galactosyltransferase, EC 2.4.1.37, EC 2.4.1.40, Fucosylglycoprotein 3-alpha-galactosyltransferase, Fucosylglycoprotein alpha-N-acetylgalactosaminyltransferase, Glycoprotein-fucosylgalactoside alpha-galactosyltransferase, Glycoprotein-fucosylgalactoside alpha-N-acetylgalactosaminyltransferase, GTB, Histo-blood group A transferase, histo-blood group A2 transferase, histo-blood group ABO system transferase, Histo-blood group B transferase, NAGAT
Host Species: Mouse
Molecular Weight of Antigen: __
Quantity: 7 mL
Primary or Secondary: Primary
Test Specificity: The antibody HEB-20 reacts with human blood group B. The specificity of the antibody HEB-20 was confirmed by comparison of specificity and reactivity to standard reagent using 5.000 samples of blood. The monoclonal antibody HEB-20 shows specific staining of erythrocytes and vascular epithelium of blood group B controls and no staining in group A controls. This monoclonal antibody is applicable for tissue staining in tumor patients with blood groups B and AB. Blood group antigens are generally defined as molecules formed by sequential addition of saccharides to the carbohydrate side chains of lipids and proteins detected on erythrocytes and certain epithelial cells. The A, B and H antigens are reported to undergo modulation during malignant cellular transformation. Blood group related antigens represent a group of carbohydrate determinants carried on both glycolipids and glycoproteins. They are usually mucin type, and are detected on erythrocytes, certain epithelial cells, and in secretions of certain individuals. Sixteen genetically and biosynthetically distinct but inter related specificities belong to this group of antigens, including A, B, H, Lewis A, Lewis B, Lewis X, Lewis Y, and precursor type 1 chain antigens.
Content And Storage: Store at 4C.
Isotype: IgG1 κ
Antigen:
ABO, Blood Group A Antigen
Classification:
Monoclonal
Conjugate:
Unconjugated
Formulation:
10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Gene Symbols:
ABO
Immunogen:
Mixture of erythrocytes of group B and glycoprotein fraction isolated from saliva of secretors with blood group B
Purification Method:
Protein L purified
Regulatory Status:
RUO
Gene ID (Entrez):
28
Target Species:
Human
Form:
Purified
Applications:
Immunohistochemistry (Paraffin)
Clone:
HEB-20
Dilution:
Immunohistochemistry-Paraffin
Gene Alias:
A transferase, A3GALNT, A3GALT1, ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase;transferase B, alpha 1-3-galactosyltransferase), ABO glycosyltransferase, B transferase, B(A) alpha-1,3-galactosyltransferase, EC 2.4.1.37, EC 2.4.1.40, Fucosylglycoprotein 3-alpha-galactosyltransferase, Fucosylglycoprotein alpha-N-acetylgalactosaminyltransferase, Glycoprotein-fucosylgalactoside alpha-galactosyltransferase, Glycoprotein-fucosylgalactoside alpha-N-acetylgalactosaminyltransferase, GTB, Histo-blood group A transferase, histo-blood group A2 transferase, histo-blood group ABO system transferase, Histo-blood group B transferase, NAGAT
Host Species:
Mouse
Molecular Weight of Antigen:
__
Quantity:
7 mL
Primary or Secondary:
Primary
Test Specificity:
The antibody HEB-20 reacts with human blood group B. The specificity of the antibody HEB-20 was confirmed by comparison of specificity and reactivity to standard reagent using 5.000 samples of blood. The monoclonal antibody HEB-20 shows specific staining of erythrocytes and vascular epithelium of blood group B controls and no staining in group A controls. This monoclonal antibody is applicable for tissue staining in tumor patients with blood groups B and AB. Blood group antigens are generally defined as molecules formed by sequential addition of saccharides to the carbohydrate side chains of lipids and proteins detected on erythrocytes and certain epithelial cells. The A, B and H antigens are reported to undergo modulation during malignant cellular transformation. Blood group related antigens represent a group of carbohydrate determinants carried on both glycolipids and glycoproteins. They are usually mucin type, and are detected on erythrocytes, certain epithelial cells, and in secretions of certain individuals. Sixteen genetically and biosynthetically distinct but inter related specificities belong to this group of antigens, including A, B, H, Lewis A, Lewis B, Lewis X, Lewis Y, and precursor type 1 chain antigens.
Content And Storage:
Store at 4C.
Isotype:
IgG1 κ
Antigen: Chromogranin A
Classification: Monoclonal
Conjugate: Unconjugated
Formulation: 10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Gene Symbols: CHGA
Immunogen: Recombinant human Chromogranin A protein (Uniprot: P10645)
Purification Method: Protein A or G purified
Regulatory Status: RUO
Gene ID (Entrez): 1113
Target Species: Human, Mouse, Rat, Porcine, Monkey
Form: Purified
Applications: Immunohistochemistry (Paraffin)
Clone: CGA/413 + CHGA/777 + CHGA/798
Dilution: Immunohistochemistry-Paraffin
Gene Alias: betagranin (N-terminal fragment of chromogranin A), CGA, chromogranin A (parathyroid secretory protein 1), chromogranin-A, parathyroid secretory protein 1, Pituitary secretory protein I, SP-I
Host Species: Mouse
Molecular Weight of Antigen: __
Quantity: 7 mL
Primary or Secondary: Primary
Test Specificity: Chromogranin A is present in neuroendocrine cells throughout the body, including the neuroendocrine cells of the large and small intestine, adrenal medulla and pancreatic islets. It is an excellent marker for carcinoid tumors, pheochromocytomas, paragangliomas, and other neuroendocrine tumors. Co-expression of chromogranin A and neuron specific enolase (NSE) is common in neuroendocrine neoplasms. Reportedly, co-expression of certain keratins and chromogranin indicates neuroendocrine lineage. The presence of strong anti-chromogranin staining and absence of anti-keratin staining should raise the possibility of paraganglioma. The co-expression of chromogranin and NSE is typical of neuroendocrine neoplasms. Most pituitary adenomas and prolactinomas readily express chromogranin.
Content And Storage: Store at 4C.
Isotype: IgG2b κ
Antigen:
Chromogranin A
Classification:
Monoclonal
Conjugate:
Unconjugated
Formulation:
10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Gene Symbols:
CHGA
Immunogen:
Recombinant human Chromogranin A protein (Uniprot: P10645)
Purification Method:
Protein A or G purified
Regulatory Status:
RUO
Gene ID (Entrez):
1113
Target Species:
Human, Mouse, Rat, Porcine, Monkey
Form:
Purified
Applications:
Immunohistochemistry (Paraffin)
Clone:
CGA/413 + CHGA/777 + CHGA/798
Dilution:
Immunohistochemistry-Paraffin
Gene Alias:
betagranin (N-terminal fragment of chromogranin A), CGA, chromogranin A (parathyroid secretory protein 1), chromogranin-A, parathyroid secretory protein 1, Pituitary secretory protein I, SP-I
Host Species:
Mouse
Molecular Weight of Antigen:
__
Quantity:
7 mL
Primary or Secondary:
Primary
Test Specificity:
Chromogranin A is present in neuroendocrine cells throughout the body, including the neuroendocrine cells of the large and small intestine, adrenal medulla and pancreatic islets. It is an excellent marker for carcinoid tumors, pheochromocytomas, paragangliomas, and other neuroendocrine tumors. Co-expression of chromogranin A and neuron specific enolase (NSE) is common in neuroendocrine neoplasms. Reportedly, co-expression of certain keratins and chromogranin indicates neuroendocrine lineage. The presence of strong anti-chromogranin staining and absence of anti-keratin staining should raise the possibility of paraganglioma. The co-expression of chromogranin and NSE is typical of neuroendocrine neoplasms. Most pituitary adenomas and prolactinomas readily express chromogranin.
Content And Storage:
Store at 4C.
Isotype:
IgG2b κ
Antigen: Chromogranin A
Classification: Monoclonal
Conjugate: Unconjugated
Formulation: 10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Gene Symbols: CHGA
Immunogen: Recombinant human Chromogranin A protein (Uniprot: P10645)
Purification Method: Protein A or G purified
Regulatory Status: RUO
Gene ID (Entrez): 1113
Target Species: Human, Rat (Negative)
Form: Purified
Applications: Immunohistochemistry (Paraffin)
Clone: CHGA/765
Dilution: Immunohistochemistry-Paraffin
Gene Alias: betagranin (N-terminal fragment of chromogranin A), CGA, chromogranin A (parathyroid secretory protein 1), chromogranin-A, parathyroid secretory protein 1, Pituitary secretory protein I, SP-I
Host Species: Mouse
Molecular Weight of Antigen: __
Quantity: 7 mL
Primary or Secondary: Primary
Test Specificity: Chromogranin A is present in neuroendocrine cells throughout the body, including the neuroendocrine cells of the large and small intestine, adrenal medulla and pancreatic islets. It is an excellent marker for carcinoid tumors, pheochromocytomas, paragangliomas, and other neuroendocrine tumors. Co-expression of chromogranin A and neuron specific enolase (NSE) is common in neuroendocrine neoplasms. Reportedly, co-expression of certain keratins and chromogranin indicates neuroendocrine lineage. The presence of strong anti-chromogranin staining and absence of anti-keratin staining should raise the possibility of paraganglioma. The co-expression of chromogranin and NSE is typical of neuroendocrine neoplasms. Most pituitary adenomas and prolactinomas readily express chromogranin.
Content And Storage: Store at 4C.
Isotype: IgG2a κ
Antigen:
Chromogranin A
Classification:
Monoclonal
Conjugate:
Unconjugated
Formulation:
10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Gene Symbols:
CHGA
Immunogen:
Recombinant human Chromogranin A protein (Uniprot: P10645)
Purification Method:
Protein A or G purified
Regulatory Status:
RUO
Gene ID (Entrez):
1113
Target Species:
Human, Rat (Negative)
Form:
Purified
Applications:
Immunohistochemistry (Paraffin)
Clone:
CHGA/765
Dilution:
Immunohistochemistry-Paraffin
Gene Alias:
betagranin (N-terminal fragment of chromogranin A), CGA, chromogranin A (parathyroid secretory protein 1), chromogranin-A, parathyroid secretory protein 1, Pituitary secretory protein I, SP-I
Host Species:
Mouse
Molecular Weight of Antigen:
__
Quantity:
7 mL
Primary or Secondary:
Primary
Test Specificity:
Chromogranin A is present in neuroendocrine cells throughout the body, including the neuroendocrine cells of the large and small intestine, adrenal medulla and pancreatic islets. It is an excellent marker for carcinoid tumors, pheochromocytomas, paragangliomas, and other neuroendocrine tumors. Co-expression of chromogranin A and neuron specific enolase (NSE) is common in neuroendocrine neoplasms. Reportedly, co-expression of certain keratins and chromogranin indicates neuroendocrine lineage. The presence of strong anti-chromogranin staining and absence of anti-keratin staining should raise the possibility of paraganglioma. The co-expression of chromogranin and NSE is typical of neuroendocrine neoplasms. Most pituitary adenomas and prolactinomas readily express chromogranin.
Content And Storage:
Store at 4C.
Isotype:
IgG2a κ