NBP248275
IPO-38 Antibody (IPO-38) - IHC-Prediluted, Novus Biologicals™
Manufacturer: Novus Biologicals
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | NBP248275-Each-of-1 | In Stock | ₹ 43,336.14 |
NBP248275 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 43,336.14
GST (18%): ₹ 7,800.505
Total Price: ₹ 51,136.645
Antigen
IPO-38
Classification
Monoclonal
Conjugate
Unconjugated
Formulation
10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Immunogen
Spleen cells of a patient with hairy cell leukemia
Purification Method
Protein L or PEG purified
Regulatory Status
RUO
Test Specificity
Recognizes a protein of 14-16kDa, which is a novel nuclear antigen of proliferating cells. IPO-38 antigen is present in the nuclei of proliferating cells such as Hodgkin s disease and non-Hodgkin s lymphomas, different forms of leukemias, breast and colorectal carcinomas, and PHA-stimulated lymphocytes. It is not expressed in the cells of non-stimulated lymphocytes and granulocytes. IPO-38 may be a useful marker of cell proliferation during monitoring of tumor progression.
Content And Storage
Store at 4C.
Isotype
IgM κ
Applications
Immunohistochemistry (Paraffin)
Clone
IPO-38
Dilution
Immunohistochemistry-Paraffin
Host Species
Mouse
Molecular Weight of Antigen
14.5 kDa
Quantity
7 mL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Form
Purified
Related Products
Description
- IPO-38 Monoclonal specifically detects IPO-38 in Human, Mouse, Rat samples
- It is validated for Immunohistochemistry, Immunohistochemistry-Paraffin.
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Antigen: IPO-38
Classification: Monoclonal
Conjugate: Unconjugated
Formulation: 10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Immunogen: Spleen cells of a patient with hairy cell leukemia
Purification Method: Protein L or PEG purified
Regulatory Status: RUO
Test Specificity: Recognizes a protein of 14-16kDa, which is a novel nuclear antigen of proliferating cells. IPO-38 antigen is present in the nuclei of proliferating cells such as Hodgkin s disease and non-Hodgkin s lymphomas, different forms of leukemias, breast and colorectal carcinomas, and PHA-stimulated lymphocytes. It is not expressed in the cells of non-stimulated lymphocytes and granulocytes. IPO-38 may be a useful marker of cell proliferation during monitoring of tumor progression.
Content And Storage: Store at 4C.
Isotype: IgM κ
Applications: Immunohistochemistry (Paraffin)
Clone: IPO-38
Dilution: Immunohistochemistry-Paraffin
Host Species: Mouse
Molecular Weight of Antigen: 14.5 kDa
Quantity: 7 mL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Form: Purified
Antigen:
IPO-38
Classification:
Monoclonal
Conjugate:
Unconjugated
Formulation:
10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Immunogen:
Spleen cells of a patient with hairy cell leukemia
Purification Method:
Protein L or PEG purified
Regulatory Status:
RUO
Test Specificity:
Recognizes a protein of 14-16kDa, which is a novel nuclear antigen of proliferating cells. IPO-38 antigen is present in the nuclei of proliferating cells such as Hodgkin s disease and non-Hodgkin s lymphomas, different forms of leukemias, breast and colorectal carcinomas, and PHA-stimulated lymphocytes. It is not expressed in the cells of non-stimulated lymphocytes and granulocytes. IPO-38 may be a useful marker of cell proliferation during monitoring of tumor progression.
Content And Storage:
Store at 4C.
Isotype:
IgM κ
Applications:
Immunohistochemistry (Paraffin)
Clone:
IPO-38
Dilution:
Immunohistochemistry-Paraffin
Host Species:
Mouse
Molecular Weight of Antigen:
14.5 kDa
Quantity:
7 mL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Form:
Purified
Antigen: Bcl-2
Classification: Monoclonal
Conjugate: Unconjugated
Formulation: 10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Immunogen: Recombinant full-length human bcl-2 protein (Uniprot: P10415)
Purification Method: Protein A or G purified
Regulatory Status: RUO
Test Specificity: This antibody recognizes a protein of 25-26kDa, identified as the Bcl-2 lpha oncoprotein. It shows no cross-reaction with Bcl-x or Bax protein. Expression of Bcl-2 lpha oncoprotein inhibits the programmed cell death (apoptosis). In most follicular lymphomas, neoplastic germinal centers express high levels of Bcl-2 lpha protein, whereas the normal or hyperplastic germinal centers are negative. Consequently, this antibody is valuable when distinguishing between reactive and neoplastic follicular proliferation in lymph node biopsies. It may also be used in distinguishing between those follicular lymphomas that express Bcl-2 protein and the small number in which the neoplastic cells are Bcl-2 negative.
Content And Storage: Store at 4C.
Isotype: IgG1 κ
Applications: Immunohistochemistry, Immunohistochemistry (Paraffin)
Clone: BCL2/782
Dilution: Immunohistochemistry, Immunohistochemistry-Paraffin
Host Species: Mouse
Molecular Weight of Antigen: 25.5 kDa
Quantity: 7 mL
Primary or Secondary: Primary
Target Species: Human
Form: Purified
Antigen:
Bcl-2
Classification:
Monoclonal
Conjugate:
Unconjugated
Formulation:
10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Immunogen:
Recombinant full-length human bcl-2 protein (Uniprot: P10415)
Purification Method:
Protein A or G purified
Regulatory Status:
RUO
Test Specificity:
This antibody recognizes a protein of 25-26kDa, identified as the Bcl-2 lpha oncoprotein. It shows no cross-reaction with Bcl-x or Bax protein. Expression of Bcl-2 lpha oncoprotein inhibits the programmed cell death (apoptosis). In most follicular lymphomas, neoplastic germinal centers express high levels of Bcl-2 lpha protein, whereas the normal or hyperplastic germinal centers are negative. Consequently, this antibody is valuable when distinguishing between reactive and neoplastic follicular proliferation in lymph node biopsies. It may also be used in distinguishing between those follicular lymphomas that express Bcl-2 protein and the small number in which the neoplastic cells are Bcl-2 negative.
Content And Storage:
Store at 4C.
Isotype:
IgG1 κ
Applications:
Immunohistochemistry, Immunohistochemistry (Paraffin)
Clone:
BCL2/782
Dilution:
Immunohistochemistry, Immunohistochemistry-Paraffin
Host Species:
Mouse
Molecular Weight of Antigen:
25.5 kDa
Quantity:
7 mL
Primary or Secondary:
Primary
Target Species:
Human
Form:
Purified
Antigen: MITF
Classification: Monoclonal
Conjugate: Unconjugated
Formulation: 10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Immunogen: NH2 terminus fragment of human MITF (Uniprot: O75030)
Purification Method: Protein A or G purified
Regulatory Status: RUO
Test Specificity: MITF (microphthalmia transcription factor) is a basic helix-loop-helix-leucine-zipper (bHLH-Zip) transcription factor that regulates the development and survival of melanocytes and retinal pigment epithelium, and also is involved in transcription of pigmentation enzyme genes such as tyrosinase TRP1 and TRP2. MITF has been shown to be phosphorylated by MAP kinase in response to c-kit activation, resulting in upregulation of MITF transcriptional activity. Mutations of the MITF gene are associated with the autosomal dominant hereditary deafness and pigmentation condition, Waardenburg Syndrome type 2A. Multiple isoforms of MITF exist, including MITF-A, MITF-B, MITF-C, MITF-H, and MITF-M, which differ in the amino-terminal domain and in their expression patterns. The MITF-M isoform is restricted to the melanocyte cell lineage. Anti-MITF, D5, recognizes a nuclear protein, which is expressed in the majority of primary and metastatic epithelioid malignant melanomas as well as in normal melanocytes, benign nevi and dysplastic nevi.
Content And Storage: Store at 4C.
Isotype: IgG1 κ
Applications: Immunohistochemistry (Paraffin)
Clone: SPM290
Dilution: Immunohistochemistry-Paraffin
Host Species: Mouse
Molecular Weight of Antigen: __
Quantity: 7 mL
Primary or Secondary: Primary
Target Species: Human, Mouse (Negative), Rat (Negative)
Form: Purified
Antigen:
MITF
Classification:
Monoclonal
Conjugate:
Unconjugated
Formulation:
10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Immunogen:
NH2 terminus fragment of human MITF (Uniprot: O75030)
Purification Method:
Protein A or G purified
Regulatory Status:
RUO
Test Specificity:
MITF (microphthalmia transcription factor) is a basic helix-loop-helix-leucine-zipper (bHLH-Zip) transcription factor that regulates the development and survival of melanocytes and retinal pigment epithelium, and also is involved in transcription of pigmentation enzyme genes such as tyrosinase TRP1 and TRP2. MITF has been shown to be phosphorylated by MAP kinase in response to c-kit activation, resulting in upregulation of MITF transcriptional activity. Mutations of the MITF gene are associated with the autosomal dominant hereditary deafness and pigmentation condition, Waardenburg Syndrome type 2A. Multiple isoforms of MITF exist, including MITF-A, MITF-B, MITF-C, MITF-H, and MITF-M, which differ in the amino-terminal domain and in their expression patterns. The MITF-M isoform is restricted to the melanocyte cell lineage. Anti-MITF, D5, recognizes a nuclear protein, which is expressed in the majority of primary and metastatic epithelioid malignant melanomas as well as in normal melanocytes, benign nevi and dysplastic nevi.
Content And Storage:
Store at 4C.
Isotype:
IgG1 κ
Applications:
Immunohistochemistry (Paraffin)
Clone:
SPM290
Dilution:
Immunohistochemistry-Paraffin
Host Species:
Mouse
Molecular Weight of Antigen:
__
Quantity:
7 mL
Primary or Secondary:
Primary
Target Species:
Human, Mouse (Negative), Rat (Negative)
Form:
Purified
Antigen: Mitochondria
Classification: Monoclonal
Conjugate: Unconjugated
Formulation: 10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Immunogen: Semi-purified mitochondrial preparation
Purification Method: Protein A or G purified
Regulatory Status: RUO
Test Specificity: monoclonal antibody MTC02 recognizes a 60kDa antigen associated with the mitochondria in human cells. It is a part of a new panel of reagents, which recognizes subcellular organelles or compartments of human cells. These markers may be useful in identification of these organelles in cells, tissues, and biochemical preparations. monoclonal antibody MTC02 recognizes an antigen associated with the mitochondria in human cells only. It can be used to stain the mitochondria in cell or tissue preparations and can be used as a mitochondrial marker in subcellular fractions. It produces a spaghetti-like pattern in normal and malignant cells and may be used to stain mitochondria of cells in fixed or frozen tissue sections. It can also be used with paraformaldehyde fixed frozen tissue or cell preparations. monoclonal antibody MTC02 is an excellent marker for human cells in xenographic model research. It reacts specifically with human cells, including neurons and embryonic stem cells.
Content And Storage: Store at 4C.
Isotype: IgG1 κ
Applications: Immunohistochemistry, Immunohistochemistry (Paraffin)
Clone: AE-1
Dilution: Immunohistochemistry, Immunohistochemistry-Paraffin
Host Species: Mouse
Molecular Weight of Antigen: 60 kDa
Quantity: 7 mL
Primary or Secondary: Primary
Target Species: Human, Mouse (Negative), Rat (Negative)
Form: Purified
Antigen:
Mitochondria
Classification:
Monoclonal
Conjugate:
Unconjugated
Formulation:
10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Immunogen:
Semi-purified mitochondrial preparation
Purification Method:
Protein A or G purified
Regulatory Status:
RUO
Test Specificity:
monoclonal antibody MTC02 recognizes a 60kDa antigen associated with the mitochondria in human cells. It is a part of a new panel of reagents, which recognizes subcellular organelles or compartments of human cells. These markers may be useful in identification of these organelles in cells, tissues, and biochemical preparations. monoclonal antibody MTC02 recognizes an antigen associated with the mitochondria in human cells only. It can be used to stain the mitochondria in cell or tissue preparations and can be used as a mitochondrial marker in subcellular fractions. It produces a spaghetti-like pattern in normal and malignant cells and may be used to stain mitochondria of cells in fixed or frozen tissue sections. It can also be used with paraformaldehyde fixed frozen tissue or cell preparations. monoclonal antibody MTC02 is an excellent marker for human cells in xenographic model research. It reacts specifically with human cells, including neurons and embryonic stem cells.
Content And Storage:
Store at 4C.
Isotype:
IgG1 κ
Applications:
Immunohistochemistry, Immunohistochemistry (Paraffin)
Clone:
AE-1
Dilution:
Immunohistochemistry, Immunohistochemistry-Paraffin
Host Species:
Mouse
Molecular Weight of Antigen:
60 kDa
Quantity:
7 mL
Primary or Secondary:
Primary
Target Species:
Human, Mouse (Negative), Rat (Negative)
Form:
Purified