NBP248286

PD-1 Antibody (SPM597) - IHC-Prediluted, Novus Biologicals™

Manufacturer: Novus Biologicals

Select a Size

Pack Size SKU Availability Price
Each of 1 NBP248286-Each-of-1 In Stock ₹ 45,860.16

NBP248286 - Each of 1

₹ 45,860.16

In Stock

Quantity

1

Base Price: ₹ 45,860.16

GST (18%): ₹ 8,254.829

Total Price: ₹ 54,114.989

Antigen

PD-1

Classification

Monoclonal

Conjugate

Unconjugated

Formulation

10mM PBS and 0.05% BSA with 0.05% Sodium Azide

Gene Symbols

PDCD1

Immunogen

Recombinant full-length human PD-1 protein (Uniprot: Q15116)

Purification Method

Protein A or G purified

Regulatory Status

RUO

Primary or Secondary

Primary

Test Specificity

PDCD-1 (programmed cell death-1 protein), also designated CD279, is a type I transmembrane receptor and a member of the immunoglobin gene superfamily. It is expressed on activated T-cells, B-cells, and myeloid cells. Anti-PDCD-1 is a marker of angioimmunoblastic lymphoma and suggests a unique cell of origin for this neoplasm. Unlike CD10 and BCL6, PDCD-1 is expressed by few B-cells, so anti-PDCD-1 may be a more specific and useful diagnostic marker in angioimmunoblastic lymphoma. In addition, PDCD-1 expression provides evidence that angioimmunoblastic lymphoma is a neoplasm derived from germinal center-associated T-cells.

Content And Storage

Store at 4C.

Isotype

IgG1 κ

Applications

Immunohistochemistry (Paraffin)

Clone

SPM597

Dilution

Immunohistochemistry-Paraffin

Gene Alias

CD279, CD279 antigen, hPD-1, PD1hPD-l, programmed cell death 1, programmed cell death protein 1, Protein PD-1, SLEB2

Host Species

Mouse

Molecular Weight of Antigen

55 kDa

Quantity

7 mL

Research Discipline

Apoptosis, Stem Cell Markers

Gene ID (Entrez)

5133

Target Species

Human

Form

Purified

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Description

  • PD-1 Monoclonal specifically detects PD-1 in Human samples
  • It is validated for Immunohistochemistry, Immunohistochemistry-Paraffin.

Compare Similar Items

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Img

Novus Biologicals

NBP248286

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Antigen:
PD-1

Classification:
Monoclonal

Conjugate:
Unconjugated

Formulation:
10mM PBS and 0.05% BSA with 0.05% Sodium Azide

Gene Symbols:
PDCD1

Immunogen:
Recombinant full-length human PD-1 protein (Uniprot: Q15116)

Purification Method:
Protein A or G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
PDCD-1 (programmed cell death-1 protein), also designated CD279, is a type I transmembrane receptor and a member of the immunoglobin gene superfamily. It is expressed on activated T-cells, B-cells, and myeloid cells. Anti-PDCD-1 is a marker of angioimmunoblastic lymphoma and suggests a unique cell of origin for this neoplasm. Unlike CD10 and BCL6, PDCD-1 is expressed by few B-cells, so anti-PDCD-1 may be a more specific and useful diagnostic marker in angioimmunoblastic lymphoma. In addition, PDCD-1 expression provides evidence that angioimmunoblastic lymphoma is a neoplasm derived from germinal center-associated T-cells.

Content And Storage:
Store at 4C.

Isotype:
IgG1 κ

Applications:
Immunohistochemistry (Paraffin)

Clone:
SPM597

Dilution:
Immunohistochemistry-Paraffin

Gene Alias:
CD279, CD279 antigen, hPD-1, PD1hPD-l, programmed cell death 1, programmed cell death protein 1, Protein PD-1, SLEB2

Host Species:
Mouse

Molecular Weight of Antigen:
55 kDa

Quantity:
7 mL

Research Discipline:
Apoptosis, Stem Cell Markers

Gene ID (Entrez):
5133

Target Species:
Human

Form:
Purified

Img

Novus Biologicals

NBP248287

--


Antigen:
EpCAM/TROP1

Classification:
Monoclonal

Conjugate:
Unconjugated

Formulation:
10mM PBS and 0.05% BSA with 0.05% Sodium Azide

Gene Symbols:
EPCAM

Immunogen:
Neuraminidase treated GLS-1 human small cell lung carcinoma cells

Purification Method:
Protein A or G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
Binding epitope of this antibody is located in the first EGF-like repeat domain (EGF1) between amino acids 27-59 of Ep-CAM.EGP40 is a 40-43kDa transmembrane epithelial glycoprotein, also identified as epithelial specific antigen (ESA), or epithelial cellular adhesion molecule (Ep-CAM). It is expressed on baso-lateral cell surface in most simple epithelia and a vast majority of carcinomas with the exception of adult squamous epithelium, hepatocytes and gastric epithelial cells. This antibody has been used to distinguish adenocarcinoma from pleural mesothelioma and hepatocellular carcinoma. This antibody is also useful in distinguishing serous carcinomas of the ovary from mesothelioma.

Content And Storage:
Store at 4C.

Isotype:
IgG1 κ

Applications:
Immunohistochemistry (Paraffin)

Clone:
MOC-31

Dilution:
Immunohistochemistry-Paraffin

Gene Alias:
17-1A, 323/A3, ACSTD1, antigen identified by monoclonal AUA1, CD326 antigen, Cell surface glycoprotein Trop-1, chromosome 4, surface marker (35kD glycoprotein), DIAR5, EGP, EGP-2, EGP314, EGP40, EpCAM, epithelial cell adhesion molecule, Epithelial cell surface antigen, Epithelial glycoprotein, Epithelial glycoprotein 314, ESA, GA733-2EGP34, hEGP314, HNPCC8, KS 1/4 antigen, KS1/4, KSAHEA125, M1S2, M4S1Ly74, Major gastrointestinal tumor-associated protein GA733-2, MIC18MH99, MOC31, TACST-1, TACSTD1, TROP1CD326, Tumor-associated calcium signal transducer 1CO-17A

Host Species:
Mouse

Molecular Weight of Antigen:
41 kDa

Quantity:
7 mL

Research Discipline:
Cancer, Cancer Stem Cells, Tumor Biomarkers

Gene ID (Entrez):
4072

Target Species:
Human, Rat (Negative)

Form:
Purified

Img

Novus Biologicals

NBP248289

--


Antigen:
EpCAM/TROP1

Classification:
Monoclonal

Conjugate:
Unconjugated

Formulation:
10mM PBS and 0.05% BSA with 0.05% Sodium Azide

Gene Symbols:
EPCAM

Immunogen:
Recombinant human EpCAM/TROP1 protein (Uniprot: P16422)

Purification Method:
Protein A or G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
EGP40 is a 40-43kDa transmembrane epithelial glycoprotein, also identified as epithelial specific antigen (ESA), or epithelial cellular adhesion molecule (Ep-CAM). It is expressed on baso-lateral cell surface in most simple epithelia and a vast majority of carcinomas with the exception of adult squamous epithelium, hepatocytes and gastric epithelial cells. This antibody has been used to distinguish adenocarcinoma from pleural mesothelioma and hepatocellular carcinoma. This antibody is also useful in distinguishing serous carcinomas of the ovary from mesothelioma.

Content And Storage:
Store at 4C.

Isotype:
IgG1 κ

Applications:
Immunohistochemistry (Paraffin)

Clone:
EGP40/837

Dilution:
Immunohistochemistry-Paraffin

Gene Alias:
17-1A, 323/A3, ACSTD1, antigen identified by monoclonal AUA1, CD326 antigen, Cell surface glycoprotein Trop-1, chromosome 4, surface marker (35kD glycoprotein), DIAR5, EGP, EGP-2, EGP314, EGP40, EpCAM, epithelial cell adhesion molecule, Epithelial cell surface antigen, Epithelial glycoprotein, Epithelial glycoprotein 314, ESA, GA733-2EGP34, hEGP314, HNPCC8, KS 1/4 antigen, KS1/4, KSAHEA125, M1S2, M4S1Ly74, Major gastrointestinal tumor-associated protein GA733-2, MIC18MH99, MOC31, TACST-1, TACSTD1, TROP1CD326, Tumor-associated calcium signal transducer 1CO-17A

Host Species:
Mouse

Molecular Weight of Antigen:
41 kDa

Quantity:
7 mL

Research Discipline:
Cancer, Cancer Stem Cells, Tumor Biomarkers

Gene ID (Entrez):
4072

Target Species:
Human, Mouse (Negative), Rat (Negative)

Form:
Purified

Img

Novus Biologicals

NBP248290

--


Antigen:
EpCAM/TROP1

Classification:
Monoclonal

Conjugate:
Unconjugated

Formulation:
10mM PBS and 0.05% BSA with 0.05% Sodium Azide

Gene Symbols:
EPCAM

Immunogen:
Recombinant human EpCAM/TROP1 protein (full-length and fragments) (Uniprot: P16422 )

Purification Method:
Protein A or G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
It is a cocktail of four highly specific monoclonal antibodies that recognize extracellular as well as intracellular domains of the epithelial cellular adhesion molecule (EpCAM). It is a 40-43kDa transmembrane epithelial glycoprotein, identified as epithelial specific antigen (ESA), or EpCAM. EpCAM is expressed on baso-lateral cell surface in most simple epithelia and a vast majority of carcinomas. This epithelial antigen plays an important role as a tumor-cell marker in lymph nodes from patients with esophageal carcinoma otherwise classified as node-negative. Epithelial antigen has also been suggested as a discriminator between basal cell and baso-squamous carcinomas, and squamous cell carcinoma of the skin.

Content And Storage:
Store at 4C.

Isotype:
IgG1 κ

Applications:
Immunohistochemistry (Paraffin)

Clone:
PAN-EpCAM (Cocktail)

Dilution:
Immunohistochemistry-Paraffin

Gene Alias:
17-1A, 323/A3, ACSTD1, antigen identified by monoclonal AUA1, CD326 antigen, Cell surface glycoprotein Trop-1, chromosome 4, surface marker (35kD glycoprotein), DIAR5, EGP, EGP-2, EGP314, EGP40, EpCAM, epithelial cell adhesion molecule, Epithelial cell surface antigen, Epithelial glycoprotein, Epithelial glycoprotein 314, ESA, GA733-2EGP34, hEGP314, HNPCC8, KS 1/4 antigen, KS1/4, KSAHEA125, M1S2, M4S1Ly74, Major gastrointestinal tumor-associated protein GA733-2, MIC18MH99, MOC31, TACST-1, TACSTD1, TROP1CD326, Tumor-associated calcium signal transducer 1CO-17A

Host Species:
Mouse

Molecular Weight of Antigen:
41 kDa

Quantity:
7 mL

Research Discipline:
Cancer, Cancer Stem Cells, Tumor Biomarkers

Gene ID (Entrez):
4072

Target Species:
Human

Form:
Purified