NBP248368
MUC6 Antibody (MUC6/916) - IHC-Prediluted, Novus Biologicals™
Manufacturer: Novus Biologicals
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | NBP248368-Each-of-1 | In Stock | ₹ 44,833.44 |
NBP248368 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,833.44
GST (18%): ₹ 8,070.019
Total Price: ₹ 52,903.459
Antigen
Gastric Mucin
Classification
Monoclonal
Conjugate
Unconjugated
Formulation
10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Gene Symbols
MUC6
Immunogen
Recombinant fragment covering tandem repeats of human MUC6 protein (exact sequence is proprietary) (Uniprot: Q6W4X9)
Purification Method
Protein A or G purified
Regulatory Status
RUO
Gene ID (Entrez)
4588
Target Species
Human, Rat (Negative)
Form
Purified
Applications
Immunohistochemistry (Paraffin)
Clone
MUC6/916
Dilution
Immunohistochemistry-Paraffin
Gene Alias
Gastric mucin-6, MUC-6, mucin 6, gastric, mucin 6, oligomeric mucus/gel-forming, mucin-6
Host Species
Mouse
Molecular Weight of Antigen
252 kDa
Quantity
7 mL
Primary or Secondary
Primary
Test Specificity
The MUC6 gastric mucin is a secreted glycoprotein that plays an essential role in epithelial cyto-protection from acid, proteases, pathogenic microorganisms, and mechanical trauma in the gastrointestinal tract. Mucin 6 expression is highest in the stomach and gall bladder, with lower expression in the terminal ileum and right colon. In gastric cancer, Mucin 6 has an altered expression. In normal stomach, Mucin 6 is associated with Lewis type 2; Mucin 6 is also expressed in gastric metaplasia, duodenum and pancreas. Mucin 6 is a secretory mucin, located in the deeper mucosal folds of human gall bladder, and its expression is altered with increasing degrees of inflammation.
Content And Storage
Store at 4C.
Isotype
IgG1 κ
Related Products
Description
- MUC6 Monoclonal specifically detects MUC6 in Human, Rat (Negative) samples
- It is validated for Immunohistochemistry, Immunohistochemistry-Paraffin.
Compare Similar Items
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Antigen: Gastric Mucin
Classification: Monoclonal
Conjugate: Unconjugated
Formulation: 10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Gene Symbols: MUC6
Immunogen: Recombinant fragment covering tandem repeats of human MUC6 protein (exact sequence is proprietary) (Uniprot: Q6W4X9)
Purification Method: Protein A or G purified
Regulatory Status: RUO
Gene ID (Entrez): 4588
Target Species: Human, Rat (Negative)
Form: Purified
Applications: Immunohistochemistry (Paraffin)
Clone: MUC6/916
Dilution: Immunohistochemistry-Paraffin
Gene Alias: Gastric mucin-6, MUC-6, mucin 6, gastric, mucin 6, oligomeric mucus/gel-forming, mucin-6
Host Species: Mouse
Molecular Weight of Antigen: 252 kDa
Quantity: 7 mL
Primary or Secondary: Primary
Test Specificity: The MUC6 gastric mucin is a secreted glycoprotein that plays an essential role in epithelial cyto-protection from acid, proteases, pathogenic microorganisms, and mechanical trauma in the gastrointestinal tract. Mucin 6 expression is highest in the stomach and gall bladder, with lower expression in the terminal ileum and right colon. In gastric cancer, Mucin 6 has an altered expression. In normal stomach, Mucin 6 is associated with Lewis type 2; Mucin 6 is also expressed in gastric metaplasia, duodenum and pancreas. Mucin 6 is a secretory mucin, located in the deeper mucosal folds of human gall bladder, and its expression is altered with increasing degrees of inflammation.
Content And Storage: Store at 4C.
Isotype: IgG1 κ
Antigen:
Gastric Mucin
Classification:
Monoclonal
Conjugate:
Unconjugated
Formulation:
10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Gene Symbols:
MUC6
Immunogen:
Recombinant fragment covering tandem repeats of human MUC6 protein (exact sequence is proprietary) (Uniprot: Q6W4X9)
Purification Method:
Protein A or G purified
Regulatory Status:
RUO
Gene ID (Entrez):
4588
Target Species:
Human, Rat (Negative)
Form:
Purified
Applications:
Immunohistochemistry (Paraffin)
Clone:
MUC6/916
Dilution:
Immunohistochemistry-Paraffin
Gene Alias:
Gastric mucin-6, MUC-6, mucin 6, gastric, mucin 6, oligomeric mucus/gel-forming, mucin-6
Host Species:
Mouse
Molecular Weight of Antigen:
252 kDa
Quantity:
7 mL
Primary or Secondary:
Primary
Test Specificity:
The MUC6 gastric mucin is a secreted glycoprotein that plays an essential role in epithelial cyto-protection from acid, proteases, pathogenic microorganisms, and mechanical trauma in the gastrointestinal tract. Mucin 6 expression is highest in the stomach and gall bladder, with lower expression in the terminal ileum and right colon. In gastric cancer, Mucin 6 has an altered expression. In normal stomach, Mucin 6 is associated with Lewis type 2; Mucin 6 is also expressed in gastric metaplasia, duodenum and pancreas. Mucin 6 is a secretory mucin, located in the deeper mucosal folds of human gall bladder, and its expression is altered with increasing degrees of inflammation.
Content And Storage:
Store at 4C.
Isotype:
IgG1 κ
Antigen: G-CSF
Classification: Monoclonal
Conjugate: Unconjugated
Formulation: 10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Gene Symbols: CSF3
Immunogen: Recombinant full-length human G-CSF protein (Uniprot: P09919)
Purification Method: Protein A or G purified
Regulatory Status: RUO
Gene ID (Entrez): 1440
Target Species: Human, Monkey
Form: Purified
Applications: Immunohistochemistry (Paraffin)
Clone: CSF3/900
Dilution: Immunohistochemistry-Paraffin
Gene Alias: C17orf33, chromosome 17 open reading frame 33, colony stimulating factor 3 (granulocyte), CSF3OS, filgrastim, G-CSF, GCSFlenograstim, granulocyte colony-stimulating factor, Lenograstim, MGC45931, pluripoietin
Host Species: Mouse
Molecular Weight of Antigen: 19 kDa
Quantity: 7 mL
Primary or Secondary: Primary
Test Specificity: This monoclonal antibody recognizes granulocyte-colony stimulating factor (G-CSF) in the cytoplasm of mature granulocytes. It shows no reactivity with any other cell types. Markers of myeloid cells are useful in the identification of different levels of cellular differentiation. It reacts with early precursor and mature forms of myeloid cells. It is useful for the detection of myeloid leukemias and granulocytic sarcomas. It can be used as a marker of granulocytes in normal tissues or inflammatory processes. G-CSF is a pleiotropic cytokine that influences differentiation, proliferation and activation of the neutrophilic granulocyte lineage. The human G-CSF cDNA encodes a 207 amino acid precursor containing a 29 amino acid signal peptide that is proteolytically cleaved to form a 178 amino acid residue mature protein. Two G-CSFs share 73% sequence identity at the amino acid level.
Content And Storage: Store at 4C.
Isotype: IgG1 κ
Antigen:
G-CSF
Classification:
Monoclonal
Conjugate:
Unconjugated
Formulation:
10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Gene Symbols:
CSF3
Immunogen:
Recombinant full-length human G-CSF protein (Uniprot: P09919)
Purification Method:
Protein A or G purified
Regulatory Status:
RUO
Gene ID (Entrez):
1440
Target Species:
Human, Monkey
Form:
Purified
Applications:
Immunohistochemistry (Paraffin)
Clone:
CSF3/900
Dilution:
Immunohistochemistry-Paraffin
Gene Alias:
C17orf33, chromosome 17 open reading frame 33, colony stimulating factor 3 (granulocyte), CSF3OS, filgrastim, G-CSF, GCSFlenograstim, granulocyte colony-stimulating factor, Lenograstim, MGC45931, pluripoietin
Host Species:
Mouse
Molecular Weight of Antigen:
19 kDa
Quantity:
7 mL
Primary or Secondary:
Primary
Test Specificity:
This monoclonal antibody recognizes granulocyte-colony stimulating factor (G-CSF) in the cytoplasm of mature granulocytes. It shows no reactivity with any other cell types. Markers of myeloid cells are useful in the identification of different levels of cellular differentiation. It reacts with early precursor and mature forms of myeloid cells. It is useful for the detection of myeloid leukemias and granulocytic sarcomas. It can be used as a marker of granulocytes in normal tissues or inflammatory processes. G-CSF is a pleiotropic cytokine that influences differentiation, proliferation and activation of the neutrophilic granulocyte lineage. The human G-CSF cDNA encodes a 207 amino acid precursor containing a 29 amino acid signal peptide that is proteolytically cleaved to form a 178 amino acid residue mature protein. Two G-CSFs share 73% sequence identity at the amino acid level.
Content And Storage:
Store at 4C.
Isotype:
IgG1 κ
Antigen: SSEA-1
Classification: Monoclonal
Conjugate: Unconjugated
Formulation: 10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Gene Symbols: __
Immunogen: Purified human SSEA-1 (Uniprot: P22083)
Purification Method: Protein L or PEG purified
Regulatory Status: RUO
Gene ID (Entrez): 2526
Target Species: Human, Mouse, Rat
Form: Purified
Applications: Immunohistochemistry (Paraffin)
Clone: FUT4/815
Dilution: Immunohistochemistry-Paraffin
Gene Alias: alpha-(1,3)-fucosyltransferase, CD15, EC 2.4.1, EC 2.4.1.-, EC 2.4.1.65, ELAM-1 ligand fucosyltransferase, ELFT, FCT3AELAM ligand fucosyltransferase, Fucosyltransferase 4, fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific), Fucosyltransferase IV, fucT-IV, FUC-TIV, FUTIV, Galactoside 3-L-fucosyltransferase, Lewis X, LeX, SSEA-1, stage-specific embryonic antigen 1
Host Species: Mouse
Molecular Weight of Antigen: __
Quantity: 7 mL
Primary or Secondary: Primary
Test Specificity: CD15 plays a role in mediating phagocytosis, bactericidal activity, and chemotaxis. It is present on >95% of granulocytes including neutrophils and eosinophils and to a lesser degree on monocytes. In addition, CD15 is expressed in Reed-Sternberg cells and some epithelial cells. CD15 antibody is very useful in the identification of Hodgkin s disease. CD15 is occasionally expressed in large cell lymphomas of both B and T phenotypes which otherwise have a quite distinct histological appearance.
Content And Storage: Store at 4C.
Isotype: IgM κ
Antigen:
SSEA-1
Classification:
Monoclonal
Conjugate:
Unconjugated
Formulation:
10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Gene Symbols:
__
Immunogen:
Purified human SSEA-1 (Uniprot: P22083)
Purification Method:
Protein L or PEG purified
Regulatory Status:
RUO
Gene ID (Entrez):
2526
Target Species:
Human, Mouse, Rat
Form:
Purified
Applications:
Immunohistochemistry (Paraffin)
Clone:
FUT4/815
Dilution:
Immunohistochemistry-Paraffin
Gene Alias:
alpha-(1,3)-fucosyltransferase, CD15, EC 2.4.1, EC 2.4.1.-, EC 2.4.1.65, ELAM-1 ligand fucosyltransferase, ELFT, FCT3AELAM ligand fucosyltransferase, Fucosyltransferase 4, fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific), Fucosyltransferase IV, fucT-IV, FUC-TIV, FUTIV, Galactoside 3-L-fucosyltransferase, Lewis X, LeX, SSEA-1, stage-specific embryonic antigen 1
Host Species:
Mouse
Molecular Weight of Antigen:
__
Quantity:
7 mL
Primary or Secondary:
Primary
Test Specificity:
CD15 plays a role in mediating phagocytosis, bactericidal activity, and chemotaxis. It is present on >95% of granulocytes including neutrophils and eosinophils and to a lesser degree on monocytes. In addition, CD15 is expressed in Reed-Sternberg cells and some epithelial cells. CD15 antibody is very useful in the identification of Hodgkin s disease. CD15 is occasionally expressed in large cell lymphomas of both B and T phenotypes which otherwise have a quite distinct histological appearance.
Content And Storage:
Store at 4C.
Isotype:
IgM κ
Antigen: p21/CIP1/CDKN1A
Classification: Monoclonal
Conjugate: Unconjugated
Formulation: 10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Gene Symbols: CDKN1A
Immunogen: Recombinant full-length human p21/CIP1/CDKN1A protein (Uniprot: P38936)
Purification Method: Protein A or G purified
Regulatory Status: RUO
Gene ID (Entrez): 1026
Target Species: Human, Mouse (Negative), Rat (Negative)
Form: Purified
Applications: Immunohistochemistry (Paraffin)
Clone: CIP1/823
Dilution: Immunohistochemistry-Paraffin
Gene Alias: CAP20cyclin-dependent kinase inhibitor 1, CDK-interacting protein 1, CDKN1melanoma differentiation associated protein 6, CIP1WAF1CDK-interaction protein 1, cyclin-dependent kinase inhibitor 1A (p21, Cip1), MDA6, MDA-6, Melanoma differentiation-associated protein 6, p21, p21CIP1, p21Cip1/Waf1, PIC1, SDI1DNA synthesis inhibitor, wild-type p53-activated fragment 1
Host Species: Mouse
Molecular Weight of Antigen: 21 kDa
Quantity: 7 mL
Primary or Secondary: Primary
Test Specificity: This monoclonal antibody recognizes a 21kDa protein, identified as the p21WAF1 tumor suppressor protein. This monoclonal antibody is highly specific to p21 and shows no cross-reaction with other closely related mitotic inhibitors. p21WAF1 is a specific inhibitor of cdks and a tumor suppressor involved in the pathogenesis of a variety of malignancies. The expression of this gene acts as an inhibitor of the cell cycle during G1 phase and is tightly controlled by the tumor suppressor protein p53. Its expression is induced by the wild type, but not mutant, p53 suppressor protein. Normal cells generally display a rather intense nuclear p21 expression. Loss of p21 expression has been reported in many carcinomas (gastric carcinoma, non-small cell lung carcinoma, thyroid carcinoma).
Content And Storage: Store at 4C.
Isotype: IgG2a κ
Antigen:
p21/CIP1/CDKN1A
Classification:
Monoclonal
Conjugate:
Unconjugated
Formulation:
10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Gene Symbols:
CDKN1A
Immunogen:
Recombinant full-length human p21/CIP1/CDKN1A protein (Uniprot: P38936)
Purification Method:
Protein A or G purified
Regulatory Status:
RUO
Gene ID (Entrez):
1026
Target Species:
Human, Mouse (Negative), Rat (Negative)
Form:
Purified
Applications:
Immunohistochemistry (Paraffin)
Clone:
CIP1/823
Dilution:
Immunohistochemistry-Paraffin
Gene Alias:
CAP20cyclin-dependent kinase inhibitor 1, CDK-interacting protein 1, CDKN1melanoma differentiation associated protein 6, CIP1WAF1CDK-interaction protein 1, cyclin-dependent kinase inhibitor 1A (p21, Cip1), MDA6, MDA-6, Melanoma differentiation-associated protein 6, p21, p21CIP1, p21Cip1/Waf1, PIC1, SDI1DNA synthesis inhibitor, wild-type p53-activated fragment 1
Host Species:
Mouse
Molecular Weight of Antigen:
21 kDa
Quantity:
7 mL
Primary or Secondary:
Primary
Test Specificity:
This monoclonal antibody recognizes a 21kDa protein, identified as the p21WAF1 tumor suppressor protein. This monoclonal antibody is highly specific to p21 and shows no cross-reaction with other closely related mitotic inhibitors. p21WAF1 is a specific inhibitor of cdks and a tumor suppressor involved in the pathogenesis of a variety of malignancies. The expression of this gene acts as an inhibitor of the cell cycle during G1 phase and is tightly controlled by the tumor suppressor protein p53. Its expression is induced by the wild type, but not mutant, p53 suppressor protein. Normal cells generally display a rather intense nuclear p21 expression. Loss of p21 expression has been reported in many carcinomas (gastric carcinoma, non-small cell lung carcinoma, thyroid carcinoma).
Content And Storage:
Store at 4C.
Isotype:
IgG2a κ