NBP254344G

CD43/Sialophorin Antibody (SPN/1766R), DyLight 488, Novus Biologicals™

Manufacturer: Novus Biologicals

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Pack Size SKU Availability Price
Each of 1 NBP254344G-Each-of-1 In Stock ₹ 55,271.76

NBP254344G - Each of 1

₹ 55,271.76

In Stock

Quantity

1

Base Price: ₹ 55,271.76

GST (18%): ₹ 9,948.917

Total Price: ₹ 65,220.677

Antigen

CD43/Sialophorin

Classification

Monoclonal

Conjugate

DyLight 488

Formulation

50 mM sodium borate with 0.05% sodium azide

Gene Symbols

SPN

Immunogen

Recombinant full-length human CD43/Sialophorin protein (Uniprot: P16150)

Primary or Secondary

Primary

Test Specificity

It recognizes a cell surface glycoprotein of 95/115/135kDa (depending upon the extent of glycosylation), identified as CD43. 70-90% of T-cell lymphomas and from 22-37% of B-cell lymphomas express CD43. No reactivity has been observed with reactive B-cells. So a B-lineage population that co-expresses CD43 is highly likely to be a malignant lymphoma, especially a low-grade lymphoma, rather than a reactive B-cell population. When CD43 antibody is used in combination with anti-CD20, effective immunophenotyping of the lymphomas in formalin-fixed tissues can be obtained. Co-staining of a lymphoid infiltrate with anti-CD20 and anti-CD43 argues against a reactive process and favors a diagnosis of lymphoma.

Content And Storage

Store at 4°C in the dark.

Applications

Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)

Clone

SPN/1766R

Dilution

Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin

Gene Alias

CD43 antigen, CD43), Galactoglycoprotein, GALGP, Leukocyte sialoglycoprotein, Sialophorin, sialophorin (gpL115, leukosialin, CD43)

Host Species

Rabbit

Quantity

0.1 mL

Gene ID (Entrez)

6693

Target Species

Human

Isotype

IgG

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Description

  • CD43/Sialophorin Monoclonal specifically detects CD43/Sialophorin in Human samples
  • It is validated for Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin.

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Img

Novus Biologicals

NBP254344G

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Antigen:
CD43/Sialophorin

Classification:
Monoclonal

Conjugate:
DyLight 488

Formulation:
50 mM sodium borate with 0.05% sodium azide

Gene Symbols:
SPN

Immunogen:
Recombinant full-length human CD43/Sialophorin protein (Uniprot: P16150)

Primary or Secondary:
Primary

Test Specificity:
It recognizes a cell surface glycoprotein of 95/115/135kDa (depending upon the extent of glycosylation), identified as CD43. 70-90% of T-cell lymphomas and from 22-37% of B-cell lymphomas express CD43. No reactivity has been observed with reactive B-cells. So a B-lineage population that co-expresses CD43 is highly likely to be a malignant lymphoma, especially a low-grade lymphoma, rather than a reactive B-cell population. When CD43 antibody is used in combination with anti-CD20, effective immunophenotyping of the lymphomas in formalin-fixed tissues can be obtained. Co-staining of a lymphoid infiltrate with anti-CD20 and anti-CD43 argues against a reactive process and favors a diagnosis of lymphoma.

Content And Storage:
Store at 4°C in the dark.

Applications:
Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)

Clone:
SPN/1766R

Dilution:
Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin

Gene Alias:
CD43 antigen, CD43), Galactoglycoprotein, GALGP, Leukocyte sialoglycoprotein, Sialophorin, sialophorin (gpL115, leukosialin, CD43)

Host Species:
Rabbit

Quantity:
0.1 mL

Gene ID (Entrez):
6693

Target Species:
Human

Isotype:
IgG

Img

Novus Biologicals

NBP254346G

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Antigen:
MUC1

Classification:
Monoclonal

Conjugate:
DyLight 488

Formulation:
50 mM sodium borate with 0.05% sodium azide

Gene Symbols:
MUC1

Immunogen:
Recombinant human MUC1 protein (Uniprot: P15941 )

Primary or Secondary:
Primary

Test Specificity:
This monoclonal antibody reacts with MUC1, a large transmembrane glycoprotein expressed on the ductal surface of normal glandular epithelia. The dominant epitope of this monoclonal antibody involves both amino acids as well as sugar moieties. Neuraminidase treatment destroys the antigen. It is a very good tracer agent in CA15.3 assays. The extracellular domain of MUC1 largely consists of a highly conserved, O-glycosylated 20 amino acids tandem repeat which can occur 30-100 times per molecule depending on the length of the allele involved. In the vast majority of human carcinomas this protein is up-regulated and poorly glycosylated and appears on the cell surface in a non-polarized fashion.

Content And Storage:
Store at 4°C in the dark.

Applications:
Flow Cytometry, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)

Clone:
rMUC1/960

Dilution:
Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin

Gene Alias:
Breast carcinoma-associated antigen DF3, Carcinoma-associated mucin, CD227, CD227 antigen, DF3 antigen, EMA, episialin, H23 antigen, H23AG, KL-6, MAM6, MUC-1, MUC1/ZD, mucin 1, cell surface associated, mucin 1, transmembrane, mucin-1, Peanut-reactive urinary mucin, PEMMUC-1/SEC, PEMT, Polymorphic epithelial mucin, PUMMUC-1/X, tumor associated epithelial mucin, Tumor-associated epithelial membrane antigen, Tumor-associated mucin

Host Species:
Mouse

Quantity:
0.1 mL

Gene ID (Entrez):
4582

Target Species:
Human

Isotype:
IgG2b κ

Img

Novus Biologicals

NBP254347G

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Antigen:
Podoplanin

Classification:
Monoclonal

Conjugate:
DyLight 488

Formulation:
50 mM sodium borate with 0.05% sodium azide

Gene Symbols:
PDPN

Immunogen:
Recombinant human Podoplanin protein fragment (around aa 24-126) (exact sequence is proprietary) (Uniprot: Q86YL7)

Primary or Secondary:
Primary

Test Specificity:
__

Content And Storage:
Store at 4°C in the dark.

Applications:
Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)

Clone:
PDPN/1433

Dilution:
Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin

Gene Alias:
36-KD, aggrus, Gp36, GP40, HT1A-1, hT1alpha-1, hT1alpha-2, lung type I cell membrane associated glycoprotein, lung type-I cell membrane-associated glycoprotein (T1A-2), OTS 8, OTS8, PA2.26 antigen, podoplanin, T1A, T1-alpha

Host Species:
Mouse

Quantity:
0.1 mL

Gene ID (Entrez):
10630

Target Species:
Human

Isotype:
IgG1 κ

Img

Novus Biologicals

NBP254352G

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Antigen:
Growth Hormone

Classification:
Monoclonal

Conjugate:
DyLight 488

Formulation:
50 mM sodium borate with 0.05% sodium azide

Gene Symbols:
GH1

Immunogen:
A recombinant fragment (around aa58-187) of human Growth Hormone (GH) protein (exact sequence is proprietary) (Uniprot: P01241)

Primary or Secondary:
Primary

Test Specificity:
Pituitary growth hormone (GH) plays a crucial role in stimulating and controlling the growth, metabolism and differentiation of many mammalian cell types by modulating the synthesis of multiple mRNA species. These effects are mediated by the binding of GH to its membrane-bound receptor, GHR, and involve a phosphorylation cascade that results in the modulation of numerous signaling pathways. GH is synthesized by acidophilic or somatotropic cells of the anterior pituitary gland. Anti-GH is a useful marker in classification of pituitary tumors and the study of pituitary disease (acromegaly).

Content And Storage:
Store at 4°C in the dark.

Applications:
Flow Cytometry, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)

Clone:
SPM106

Dilution:
Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin

Gene Alias:
GHIGHD1B, GHNGrowth hormone, GH-Nsomatotropin, growth hormone 1Pituitary growth hormone, hGH-N

Host Species:
Mouse

Quantity:
0.1 mL

Gene ID (Entrez):
2688

Target Species:
Human

Isotype:
IgG2b κ