NBP254346G

MUC1 Antibody (rMUC1/960), DyLight 488, Novus Biologicals™

Manufacturer: Novus Biologicals

Select a Size

Pack Size SKU Availability Price
Each of 1 NBP254346G-Each-of-1 In Stock ₹ 55,271.76

NBP254346G - Each of 1

₹ 55,271.76

In Stock

Quantity

1

Base Price: ₹ 55,271.76

GST (18%): ₹ 9,948.917

Total Price: ₹ 65,220.677

Antigen

MUC1

Classification

Monoclonal

Conjugate

DyLight 488

Formulation

50 mM sodium borate with 0.05% sodium azide

Gene Symbols

MUC1

Immunogen

Recombinant human MUC1 protein (Uniprot: P15941 )

Research Discipline

Cancer, Cellular Markers, Extracellular Matrix, Inflammation, Signal Transduction

Gene ID (Entrez)

4582

Target Species

Human

Isotype

IgG2b κ

Applications

Flow Cytometry, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)

Clone

rMUC1/960

Dilution

Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin

Gene Alias

Breast carcinoma-associated antigen DF3, Carcinoma-associated mucin, CD227, CD227 antigen, DF3 antigen, EMA, episialin, H23 antigen, H23AG, KL-6, MAM6, MUC-1, MUC1/ZD, mucin 1, cell surface associated, mucin 1, transmembrane, mucin-1, Peanut-reactive urinary mucin, PEMMUC-1/SEC, PEMT, Polymorphic epithelial mucin, PUMMUC-1/X, tumor associated epithelial mucin, Tumor-associated epithelial membrane antigen, Tumor-associated mucin

Host Species

Mouse

Quantity

0.1 mL

Primary or Secondary

Primary

Test Specificity

This monoclonal antibody reacts with MUC1, a large transmembrane glycoprotein expressed on the ductal surface of normal glandular epithelia. The dominant epitope of this monoclonal antibody involves both amino acids as well as sugar moieties. Neuraminidase treatment destroys the antigen. It is a very good tracer agent in CA15.3 assays. The extracellular domain of MUC1 largely consists of a highly conserved, O-glycosylated 20 amino acids tandem repeat which can occur 30-100 times per molecule depending on the length of the allele involved. In the vast majority of human carcinomas this protein is up-regulated and poorly glycosylated and appears on the cell surface in a non-polarized fashion.

Content And Storage

Store at 4°C in the dark.

Description

  • MUC1 Monoclonal specifically detects MUC1 in Human samples
  • It is validated for Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin.

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Img

Novus Biologicals

NBP254346G

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Antigen:
MUC1

Classification:
Monoclonal

Conjugate:
DyLight 488

Formulation:
50 mM sodium borate with 0.05% sodium azide

Gene Symbols:
MUC1

Immunogen:
Recombinant human MUC1 protein (Uniprot: P15941 )

Research Discipline:
Cancer, Cellular Markers, Extracellular Matrix, Inflammation, Signal Transduction

Gene ID (Entrez):
4582

Target Species:
Human

Isotype:
IgG2b κ

Applications:
Flow Cytometry, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)

Clone:
rMUC1/960

Dilution:
Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin

Gene Alias:
Breast carcinoma-associated antigen DF3, Carcinoma-associated mucin, CD227, CD227 antigen, DF3 antigen, EMA, episialin, H23 antigen, H23AG, KL-6, MAM6, MUC-1, MUC1/ZD, mucin 1, cell surface associated, mucin 1, transmembrane, mucin-1, Peanut-reactive urinary mucin, PEMMUC-1/SEC, PEMT, Polymorphic epithelial mucin, PUMMUC-1/X, tumor associated epithelial mucin, Tumor-associated epithelial membrane antigen, Tumor-associated mucin

Host Species:
Mouse

Quantity:
0.1 mL

Primary or Secondary:
Primary

Test Specificity:
This monoclonal antibody reacts with MUC1, a large transmembrane glycoprotein expressed on the ductal surface of normal glandular epithelia. The dominant epitope of this monoclonal antibody involves both amino acids as well as sugar moieties. Neuraminidase treatment destroys the antigen. It is a very good tracer agent in CA15.3 assays. The extracellular domain of MUC1 largely consists of a highly conserved, O-glycosylated 20 amino acids tandem repeat which can occur 30-100 times per molecule depending on the length of the allele involved. In the vast majority of human carcinomas this protein is up-regulated and poorly glycosylated and appears on the cell surface in a non-polarized fashion.

Content And Storage:
Store at 4°C in the dark.

Img

Novus Biologicals

NBP254347G

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Antigen:
Podoplanin

Classification:
Monoclonal

Conjugate:
DyLight 488

Formulation:
50 mM sodium borate with 0.05% sodium azide

Gene Symbols:
PDPN

Immunogen:
Recombinant human Podoplanin protein fragment (around aa 24-126) (exact sequence is proprietary) (Uniprot: Q86YL7)

Research Discipline:
__

Gene ID (Entrez):
10630

Target Species:
Human

Isotype:
IgG1 κ

Applications:
Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)

Clone:
PDPN/1433

Dilution:
Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin

Gene Alias:
36-KD, aggrus, Gp36, GP40, HT1A-1, hT1alpha-1, hT1alpha-2, lung type I cell membrane associated glycoprotein, lung type-I cell membrane-associated glycoprotein (T1A-2), OTS 8, OTS8, PA2.26 antigen, podoplanin, T1A, T1-alpha

Host Species:
Mouse

Quantity:
0.1 mL

Primary or Secondary:
Primary

Test Specificity:
__

Content And Storage:
Store at 4°C in the dark.

Img

Novus Biologicals

NBP254352G

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Antigen:
Growth Hormone

Classification:
Monoclonal

Conjugate:
DyLight 488

Formulation:
50 mM sodium borate with 0.05% sodium azide

Gene Symbols:
GH1

Immunogen:
A recombinant fragment (around aa58-187) of human Growth Hormone (GH) protein (exact sequence is proprietary) (Uniprot: P01241)

Research Discipline:
__

Gene ID (Entrez):
2688

Target Species:
Human

Isotype:
IgG2b κ

Applications:
Flow Cytometry, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)

Clone:
SPM106

Dilution:
Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin

Gene Alias:
GHIGHD1B, GHNGrowth hormone, GH-Nsomatotropin, growth hormone 1Pituitary growth hormone, hGH-N

Host Species:
Mouse

Quantity:
0.1 mL

Primary or Secondary:
Primary

Test Specificity:
Pituitary growth hormone (GH) plays a crucial role in stimulating and controlling the growth, metabolism and differentiation of many mammalian cell types by modulating the synthesis of multiple mRNA species. These effects are mediated by the binding of GH to its membrane-bound receptor, GHR, and involve a phosphorylation cascade that results in the modulation of numerous signaling pathways. GH is synthesized by acidophilic or somatotropic cells of the anterior pituitary gland. Anti-GH is a useful marker in classification of pituitary tumors and the study of pituitary disease (acromegaly).

Content And Storage:
Store at 4°C in the dark.

Img

Novus Biologicals

NBP254355G

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Antigen:
CD34

Classification:
Monoclonal

Conjugate:
DyLight 488

Formulation:
50 mM sodium borate with 0.05% sodium azide

Gene Symbols:
CD34

Immunogen:
Recombinant full-length human CD34 protein (Uniprot: P28906)

Research Discipline:
Adaptive Immunity, Angiogenesis, B Cell Development and Differentiation Markers, Breast Cancer, Cancer, Cell Biology, Cellular Markers, Endothelial Cell Markers, Hematopoietic Stem Cell Markers, Hypoxia, Immunology, Innate Immunity, Mast Cell Markers, Mesenchymal Stem Cell Markers, Myeloid Cell Markers, Myeloid derived Suppressor Cell, Neuronal Cell Markers, Neuroscience, Stem Cell Markers, Tumor Suppressors

Gene ID (Entrez):
947

Target Species:
Human, Rat

Isotype:
IgG

Applications:
Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)

Clone:
HPCA1/1806R

Dilution:
Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin

Gene Alias:
CD34 antigenhematopoietic progenitor cell antigen CD34, CD34 molecule

Host Species:
Rabbit

Quantity:
0.1 mL

Primary or Secondary:
Primary

Test Specificity:
This antibody recognizes a transmembrane, heavily glycosylated protein of 90-120kDa, which is identified as CD34. Its expression is a hallmark for identifying pluripotent hematopoietic stem or progenitor cells. Its expression is gradually lost as lineage committed progenitors differentiate. CD34 is a marker of choice for staining blasts in acute myeloid leukemia. In addition, it is expressed by soft tissue tumors, such as solitary fibrous tumor and gastrointestinal stromal tumor. CD34 expression is also found in vascular endothelium. Additionally, proliferating endothelial cells overexpress this molecule than the non-proliferating endothelial cells. Anti-CD34 labels 85% of angiosarcoma and Kaposis sarcoma, but shows low specificity.

Content And Storage:
Store at 4°C in the dark.