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NBP254355G

CD34 Antibody (HPCA1/1806R), DyLight 488, Novus Biologicals™

Manufacturer: Novus Biologicals

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Pack Size SKU Availability Price
Each of 1 NBP254355G-Each-of-1 In Stock ₹ 56,298.48

NBP254355G - Each of 1

₹ 56,298.48

In Stock

Quantity

1

Base Price: ₹ 56,298.48

GST (18%): ₹ 10,133.726

Total Price: ₹ 66,432.206

Antigen

CD34

Classification

Monoclonal

Conjugate

DyLight 488

Formulation

50 mM sodium borate with 0.05% sodium azide

Gene Symbols

CD34

Immunogen

Recombinant full-length human CD34 protein (Uniprot: P28906)

Research Discipline

Adaptive Immunity, Angiogenesis, B Cell Development and Differentiation Markers, Breast Cancer, Cancer, Cell Biology, Cellular Markers, Endothelial Cell Markers, Hematopoietic Stem Cell Markers, Hypoxia, Immunology, Innate Immunity, Mast Cell Markers, Mesenchymal Stem Cell Markers, Myeloid Cell Markers, Myeloid derived Suppressor Cell, Neuronal Cell Markers, Neuroscience, Stem Cell Markers, Tumor Suppressors

Gene ID (Entrez)

947

Target Species

Human, Rat

Isotype

IgG

Applications

Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)

Clone

HPCA1/1806R

Dilution

Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin

Gene Alias

CD34 antigenhematopoietic progenitor cell antigen CD34, CD34 molecule

Host Species

Rabbit

Quantity

0.1 mL

Primary or Secondary

Primary

Test Specificity

This antibody recognizes a transmembrane, heavily glycosylated protein of 90-120kDa, which is identified as CD34. Its expression is a hallmark for identifying pluripotent hematopoietic stem or progenitor cells. Its expression is gradually lost as lineage committed progenitors differentiate. CD34 is a marker of choice for staining blasts in acute myeloid leukemia. In addition, it is expressed by soft tissue tumors, such as solitary fibrous tumor and gastrointestinal stromal tumor. CD34 expression is also found in vascular endothelium. Additionally, proliferating endothelial cells overexpress this molecule than the non-proliferating endothelial cells. Anti-CD34 labels 85% of angiosarcoma and Kaposis sarcoma, but shows low specificity.

Content And Storage

Store at 4°C in the dark.

Description

  • CD34 Monoclonal specifically detects CD34 in Human, Rat samples
  • It is validated for Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Paraffin.

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Novus Biologicals

NBP254355G

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Antigen:
CD34
Classification:
Monoclonal
Conjugate:
DyLight 488
Formulation:
50 mM sodium borate with 0.05% sodium azide
Gene Symbols:
CD34
Immunogen:
Recombinant full-length human CD34 protein (Uniprot: P28906)
Research Discipline:
Adaptive Immunity, Angiogenesis, B Cell Development and Differentiation Markers, Breast Cancer, Cancer, Cell Biology, Cellular Markers, Endothelial Cell Markers, Hematopoietic Stem Cell Markers, Hypoxia, Immunology, Innate Immunity, Mast Cell Markers, Mesenchymal Stem Cell Markers, Myeloid Cell Markers, Myeloid derived Suppressor Cell, Neuronal Cell Markers, Neuroscience, Stem Cell Markers, Tumor Suppressors
Gene ID (Entrez):
947
Target Species:
Human, Rat
Isotype:
IgG
Applications:
Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)
Clone:
HPCA1/1806R
Dilution:
Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin
Gene Alias:
CD34 antigenhematopoietic progenitor cell antigen CD34, CD34 molecule
Host Species:
Rabbit
Quantity:
0.1 mL
Primary or Secondary:
Primary
Test Specificity:
This antibody recognizes a transmembrane, heavily glycosylated protein of 90-120kDa, which is identified as CD34. Its expression is a hallmark for identifying pluripotent hematopoietic stem or progenitor cells. Its expression is gradually lost as lineage committed progenitors differentiate. CD34 is a marker of choice for staining blasts in acute myeloid leukemia. In addition, it is expressed by soft tissue tumors, such as solitary fibrous tumor and gastrointestinal stromal tumor. CD34 expression is also found in vascular endothelium. Additionally, proliferating endothelial cells overexpress this molecule than the non-proliferating endothelial cells. Anti-CD34 labels 85% of angiosarcoma and Kaposis sarcoma, but shows low specificity.
Content And Storage:
Store at 4°C in the dark.

Img

Novus Biologicals

NBP254356G

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Antigen:
Growth Hormone
Classification:
Monoclonal
Conjugate:
DyLight 488
Formulation:
50 mM sodium borate with 0.05% sodium azide
Gene Symbols:
GH1
Immunogen:
A recombinant fragment (around aa58-187) of human Growth Hormone (GH) protein (exact sequence is proprietary) (Uniprot: P01241)
Research Discipline:
__
Gene ID (Entrez):
2688
Target Species:
Human
Isotype:
IgG2b κ
Applications:
Flow Cytometry, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)
Clone:
GH/1450
Dilution:
Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin
Gene Alias:
GHIGHD1B, GHNGrowth hormone, GH-Nsomatotropin, growth hormone 1Pituitary growth hormone, hGH-N
Host Species:
Mouse
Quantity:
0.1 mL
Primary or Secondary:
Primary
Test Specificity:
Pituitary growth hormone (GH) plays a crucial role in stimulating and controlling the growth, metabolism and differentiation of many mammalian cell types by modulating the synthesis of multiple mRNA species. These effects are mediated by the binding of GH to its membrane-bound receptor, GHR, and involve a phosphorylation cascade that results in the modulation of numerous signaling pathways. GH is synthesized by acidophilic or somatotropic cells of the anterior pituitary gland. Anti-GH is a useful marker in classification of pituitary tumors and the study of pituitary disease (acromegaly).
Content And Storage:
Store at 4°C in the dark.

Img

Novus Biologicals

NBP254364G

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Antigen:
MMP-2
Classification:
Monoclonal
Conjugate:
DyLight 488
Formulation:
50 mM sodium borate with 0.05% sodium azide
Gene Symbols:
MMP2
Immunogen:
Recombinant human MMP-2 protein fragment (aa 444-575) (exact sequence is proprietary) (Uniprot: P08253)
Research Discipline:
Angiogenesis, Apoptosis, Cancer, Cell Biology, Cytoskeleton Markers, Extracellular Matrix, HIF Target Genes, Hypoxia, Metastasis, Tumor Suppressors
Gene ID (Entrez):
4313.0
Target Species:
Human
Isotype:
IgG1 κ
Applications:
Western Blot, Flow Cytometry, Immunocytochemistry, Immunofluorescence
Clone:
MMP2/1501
Dilution:
Western Blot, Flow Cytometry, Immunocytochemistry/Immunofluorescence
Gene Alias:
72 kDa gelatinase, CLG4, CLG4A72 kDa type IV collagenase, collagenase type IV-A, EC 3.4.24, EC 3.4.24.24, Gelatinase A, matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IVcollagenase), matrix metalloproteinase 2 (gelatinase A, 72kD gelatinase, 72kD type IVcollagenase), Matrix metalloproteinase-2, matrix metalloproteinase-II, MMP-2, MMP-II, MONA, neutrophil gelatinase, TBE-1matrix metalloproteinase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IVcollagenase)
Host Species:
Mouse
Quantity:
0.1 mL
Primary or Secondary:
Primary
Test Specificity:
__
Content And Storage:
Store at 4°C in the dark.

Img

Novus Biologicals

NBP254366G

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Antigen:
Filaggrin
Classification:
Monoclonal
Conjugate:
DyLight 488
Formulation:
50 mM sodium borate with 0.05% sodium azide
Gene Symbols:
FLG
Immunogen:
Recombinant human Filaggrin protein fragment (aa 198-288) (exact sequence is proprietary) (Uniprot: P20930)
Research Discipline:
__
Gene ID (Entrez):
2312
Target Species:
Human
Isotype:
IgG1 κ
Applications:
Immunohistochemistry, Immunohistochemistry (Paraffin), Immunocytochemistry, Immunofluorescence
Clone:
FLG/1561
Dilution:
Immunohistochemistry, Immunohistochemistry-Paraffin
Gene Alias:
ATOD2, epidermal filaggrin, filaggrin, Profilaggrin
Host Species:
Mouse
Quantity:
0.1 mL
Primary or Secondary:
Primary
Test Specificity:
Filaggrin is an intermediate filament-associated protein that aggregates keratin intermediate filaments in mammalian epidermis. It is initially synthesized as a polyprotein precursor, profilaggrin (consisting of multiple filaggrin units of 324 aa each), which is localized in keratohyalin granules, and is subsequently proteolytically processed into individual functional filaggrin molecules. Active filaggrin is present at a level of the epidermis where keratinocytes are in transition between the live nucleated granular layer and the anucleate cornified layer, suggesting that filaggrin aids in the terminal differentiation process by facilitating apoptotic machinery.
Content And Storage:
Store at 4°C in the dark.