Manufacturer: Fischer Scientific
Pack Size | SKU | Availability | Price |
---|---|---|---|
Each of 1 | NBP25490101-Each-of-1 | In Stock | ₹ 56,298.48 |
NBP25490101 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 56,298.48
GST (18%): ₹ 10,133.726
Total Price: ₹ 66,432.206
CD7
Monoclonal
Unconjugated
10mM PBS with No Preservative
CD7
Human T cells
Protein A or G purified
RUO
Primary
Recognizes a protein of 40kDa, identified as CD7, a member of the immunoglobulin gene superfamily. Its N-terminal amino acids 1-107 are highly homologous to Ig kappa-L chains whereas the carboxyl-terminal region of the extracellular domain is proline-rich and has been postulated to form a stalk from which the Ig domain projects. CD7 is expressed on the majority of immature and mature T-lymphocytes, and T cell leukemia. It is also found on natural killer cells, a small subpopulation of normal B cells and on malignant B cells. Cross-linking surface CD7 positively modulates T cell and NK cell activity as measured by calcium fluxes, expression of adhesion molecules, cytokine secretion and proliferation. CD7 associates directly with phosphoinositol 3'-kinase. CD7 ligation induces production of D-3 phosphoinositides and tyrosine phosphorylation.
Store at 4°C.
IgG1 κ
Flow Cytometry, Immunofluorescence
T3-3A1
Flow Cytometry 0.5 - 1ug/million cells in 0.1 ml, Immunofluorescence 0.5 - 1.0 ug/ml
CD7 antigen, CD7 antigen (p41), CD7 molecule, GP40T-cell surface antigen Leu-9, LEU-9, T-cell antigen CD7, T-cell leukemia antigen, Tp40, TP41p41 protein
Mouse
40 kDa
0.1 mg
Cytokine Research, Signal Transduction
924
Human
Purified