Bcl-6 Mouse anti-Human, Clone: BCL6/1527, Novus Biologicals™
Manufacturer: Fischer Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | NBP259598X-Each-of-1 | In Stock | ₹ 44,833.44 |
NBP259598X - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,833.44
GST (18%): ₹ 8,070.019
Total Price: ₹ 52,903.459
Antigen
Bcl-6
Classification
Monoclonal
Concentration
0.2 mg/mL
Dilution
Flow Cytometry 0.5-1 ug/million cells, Immunohistochemistry-Paraffin 1-2 ug/ml, SDS-Page, Protein Array 1:100-1:2000
Gene Alias
B-cell CLL/lymphoma 6, B-cell lymphoma 6 protein transcript, BCL-5, BCL5B-cell lymphoma 5 protein, BCL-6, BCL6A, cys-his2 zinc finger transcription factor, LAZ3ZBTB27B-cell lymphoma 6 protein, lymphoma-associated zinc finger gene on chromosome 3, Protein LAZ-3, Zinc finger and BTB domain-containing protein 27, Zinc finger protein 51ZNF51, zinc finger transcription factor BCL6S
Host Species
Mouse
Molecular Weight of Antigen
95 kDa
Quantity
100 μg
Research Discipline
Cancer, Cell Cycle and Replication, Tumor Suppressors
Gene ID (Entrez)
604
Target Species
Human
Form
Purified
Applications
Flow Cytometry, Immunohistochemistry (Paraffin), SDS-Page
Clone
BCL6/1527
Conjugate
Unconjugated
Formulation
10mM PBS with 0.05% BSA with 0.05% Sodium Azide
Gene Symbols
BCL6
Immunogen
Recombinant human bcl-6 protein fragment (around aa256-389) (Exact sequence is proprietary)
Purification Method
Protein A or G purified
Regulatory Status
RUO
Primary or Secondary
Primary
Test Specificity
The specificity of this monoclonal antibody to its intended target was validated by HuProt Array, containing more than 19,000, full-length human proteins. Recognizes a protein of 95kDa, which is identified as Bcl-6. Antibody to bcl-6 is helpful in a number of diagnostic settings: (1) In the differential diagnosis of small B-cell lymphoma. Follicular lymphoma will show bcl-6 (and CD10) positivity whereas other small B-cell lymphomas are usually negative. (2) Bcl-6 is an important prognostic marker in diffuse large B-cell lymphomas (DLBCL), where CD10, bcl-6 and MUM1/IRF4 are used to identify germinal center and activated B-cell phenotypes. (3) Bcl-6 can be valuable in distinguishing classical Hodgkin lymphoma from nodular lymphocyte predominant Hodgkin lymphoma (NLPHL). The Reed-Sternberg cells of classical Hodgkin lymphoma are bcl-6 negative whereas the large (L&H) cells of NLPHL are bcl-6 positive. In contrast, anti-Bcl-6 rarely stains mantle-cell lymphoma and MALT lymphoma.
Content And Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Isotype
IgG1 κ
Related Products
Description
- Bcl-6 Monoclonal specifically detects Bcl-6 in Human samples
- It is validated for Immunohistochemistry, Immunohistochemistry-Paraffin, Protein Array.
Compare Similar Items
Show Difference
Antigen: Bcl-6
Classification: Monoclonal
Concentration: 0.2 mg/mL
Dilution: Flow Cytometry 0.5-1 ug/million cells, Immunohistochemistry-Paraffin 1-2 ug/ml, SDS-Page, Protein Array 1:100-1:2000
Gene Alias: B-cell CLL/lymphoma 6, B-cell lymphoma 6 protein transcript, BCL-5, BCL5B-cell lymphoma 5 protein, BCL-6, BCL6A, cys-his2 zinc finger transcription factor, LAZ3ZBTB27B-cell lymphoma 6 protein, lymphoma-associated zinc finger gene on chromosome 3, Protein LAZ-3, Zinc finger and BTB domain-containing protein 27, Zinc finger protein 51ZNF51, zinc finger transcription factor BCL6S
Host Species: Mouse
Molecular Weight of Antigen: 95 kDa
Quantity: 100 μg
Research Discipline: Cancer, Cell Cycle and Replication, Tumor Suppressors
Gene ID (Entrez): 604
Target Species: Human
Form: Purified
Applications: Flow Cytometry, Immunohistochemistry (Paraffin), SDS-Page
Clone: BCL6/1527
Conjugate: Unconjugated
Formulation: 10mM PBS with 0.05% BSA with 0.05% Sodium Azide
Gene Symbols: BCL6
Immunogen: Recombinant human bcl-6 protein fragment (around aa256-389) (Exact sequence is proprietary)
Purification Method: Protein A or G purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: The specificity of this monoclonal antibody to its intended target was validated by HuProt Array, containing more than 19,000, full-length human proteins. Recognizes a protein of 95kDa, which is identified as Bcl-6. Antibody to bcl-6 is helpful in a number of diagnostic settings: (1) In the differential diagnosis of small B-cell lymphoma. Follicular lymphoma will show bcl-6 (and CD10) positivity whereas other small B-cell lymphomas are usually negative. (2) Bcl-6 is an important prognostic marker in diffuse large B-cell lymphomas (DLBCL), where CD10, bcl-6 and MUM1/IRF4 are used to identify germinal center and activated B-cell phenotypes. (3) Bcl-6 can be valuable in distinguishing classical Hodgkin lymphoma from nodular lymphocyte predominant Hodgkin lymphoma (NLPHL). The Reed-Sternberg cells of classical Hodgkin lymphoma are bcl-6 negative whereas the large (L&H) cells of NLPHL are bcl-6 positive. In contrast, anti-Bcl-6 rarely stains mantle-cell lymphoma and MALT lymphoma.
Content And Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Isotype: IgG1 κ
Antigen: Creatine Kinase BB
Classification: Monoclonal
Concentration: __
Dilution: Flow Cytometry, Immunocytochemistry/Immunofluorescence
Gene Alias: Creatine Kinase Isoenzyme
Host Species: Mouse
Molecular Weight of Antigen: __
Quantity: 100 μL
Research Discipline: __
Gene ID (Entrez): 1152
Target Species: Human
Form: Purified
Applications: Flow Cytometry, Immunocytochemistry, Immunofluorescence
Clone: 2ba6
Conjugate: Alexa Fluor 405
Formulation: 50mM Sodium Borate with 0.05% Sodium Azide
Gene Symbols: CKB
Immunogen: Human Creatine Kinase BB protein (Uniprot: P12277)
Purification Method: Protein A or G purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: The specificity of this monoclonal antibody to its intended target was validated by HuProtTM Array, containing more than 19,000, full-length human proteins. The specificity of this monoclonal antibody to its intended target was validated by HuProt Array containing more than 19,000 full-length, correctly-folded human proteins. Creatine kinases (CK) are a large family of isoenzymes that regulate levels of ATP in subcellular compartments, where they provide ATP at sites of fluctuating energy demand by the transfer of phosphates between creatine and adenine nucleotides. CKs provide the energy of phosphate hydrolysis necessary to drive the normal function of many cellular systems. In cells, the cytosolic CK enzymes consist of two subunits, which can be either B (brain type) or M (muscle type). There are three different isoenzymes: CKMM, CKBB and CKMB. This monoclonal antibody recognizes the CKBB isoenzyme and does not react with the B subunit in CKMB. It shows minimal reactivity with other human serum proteins.
Content And Storage: Store at 4C in the dark.
Isotype: IgG1 κ
Antigen: Creatine Kinase BB
Classification: Monoclonal
Concentration: __
Dilution: Flow Cytometry, Immunocytochemistry/Immunofluorescence
Gene Alias: Creatine Kinase Isoenzyme
Host Species: Mouse
Molecular Weight of Antigen: __
Quantity: 100 μL
Research Discipline: __
Gene ID (Entrez): 1152
Target Species: Human
Form: Purified
Applications: Flow Cytometry, Immunocytochemistry, Immunofluorescence
Clone: 2ba6
Conjugate: Alexa Fluor 647
Formulation: 50mM Sodium Borate with 0.05% Sodium Azide
Gene Symbols: CKB
Immunogen: Human Creatine Kinase BB protein (Uniprot: P12277)
Purification Method: Protein A or G purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: The specificity of this monoclonal antibody to its intended target was validated by HuProtTM Array, containing more than 19,000, full-length human proteins. The specificity of this monoclonal antibody to its intended target was validated by HuProt Array containing more than 19,000 full-length, correctly-folded human proteins. Creatine kinases (CK) are a large family of isoenzymes that regulate levels of ATP in subcellular compartments, where they provide ATP at sites of fluctuating energy demand by the transfer of phosphates between creatine and adenine nucleotides. CKs provide the energy of phosphate hydrolysis necessary to drive the normal function of many cellular systems. In cells, the cytosolic CK enzymes consist of two subunits, which can be either B (brain type) or M (muscle type). There are three different isoenzymes: CKMM, CKBB and CKMB. This monoclonal antibody recognizes the CKBB isoenzyme and does not react with the B subunit in CKMB. It shows minimal reactivity with other human serum proteins.
Content And Storage: Store at 4C in the dark.
Isotype: IgG1 κ