NBP259620X

SOX10 Mouse anti-Human, Mouse, Clone: SOX10/991, Novus Biologicals™

Manufacturer: Fischer Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 NBP259620X-Each-of-1 In Stock ₹ 46,886.88

NBP259620X - Each of 1

₹ 46,886.88

In Stock

Quantity

1

Base Price: ₹ 46,886.88

GST (18%): ₹ 8,439.638

Total Price: ₹ 55,326.518

Antigen

SOX10

Classification

Monoclonal

Concentration

0.2 mg/mL

Dilution

Western Blot 0.5-1 ug/ml, Flow Cytometry 0.5-1 ug/million cells, Immunocytochemistry/Immunofluorescence 1-2 ug/ml, Immunohistochemistry-Paraffin 0.5-1 ug/ml, SDS-Page, Protein Array 1:100-1:2000

Gene Alias

MGC15649, PCWH, SRY (sex determining region Y)-box 10, SRY-related HMG-box gene 10, transcription factor SOX-10, WS4C, WS4mouse, human homolog of

Host Species

Mouse

Molecular Weight of Antigen

54 kDa

Quantity

100 μg

Primary or Secondary

Primary

Test Specificity

The specificity of this monoclonal antibody to its intended target was validated by HuProtTM Array, containing more than 19,000, full-length human proteins. Recognizes a protein of ∼55kDa, identified as SOX10. This MAb is highly specific and does not cross-react with other members of the SOX-family. SOX genes comprise a family of genes that are related to the mammalian sex-determining gene SRY. These genes similarly contain sequences that encode for the HMG -box domain, which is responsible for the sequence-specific DNA-binding activity. SOX-10 is a sensitive marker of melanoma, including conventional, spindled, and desmoplastic subtypes. It is expressed by metastatic melanomas and nodal capsular nevus in sentinel lymph nodes, but not by other lymph node components such as dendritic cells, which usually express S100 protein. Commonly used melanoma markers, such as anti-HMB-45 and anti-Melan-A, are poorly expressed in desmoplastic melanomas while SOX-10 is moderately to strongly exp

Content And Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Isotype

IgG2b κ

Applications

Western Blot, Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), SDS-Page

Clone

SOX10/991

Conjugate

Unconjugated

Formulation

10mM PBS with 0.05% BSA with 0.05% Sodium Azide

Gene Symbols

SOX10

Immunogen

Recombinant human SOX10 protein fragment (around aa115-269) (exact sequence is proprietar

Purification Method

Protein A or G purified

Regulatory Status

RUO

Gene ID (Entrez)

6663

Target Species

Human, Mouse

Form

Purified

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Description

  • SOX10 Monoclonal specifically detects SOX10 in Human, Mouse samples
  • It is validated for Western Blot, Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Paraffin, Protein Array, Flow (Intracellular).

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Show Difference

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Fischer Scientific

NBP259620X

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Antigen:
SOX10

Classification:
Monoclonal

Concentration:
0.2 mg/mL

Dilution:
Western Blot 0.5-1 ug/ml, Flow Cytometry 0.5-1 ug/million cells, Immunocytochemistry/Immunofluorescence 1-2 ug/ml, Immunohistochemistry-Paraffin 0.5-1 ug/ml, SDS-Page, Protein Array 1:100-1:2000

Gene Alias:
MGC15649, PCWH, SRY (sex determining region Y)-box 10, SRY-related HMG-box gene 10, transcription factor SOX-10, WS4C, WS4mouse, human homolog of

Host Species:
Mouse

Molecular Weight of Antigen:
54 kDa

Quantity:
100 μg

Primary or Secondary:
Primary

Test Specificity:
The specificity of this monoclonal antibody to its intended target was validated by HuProtTM Array, containing more than 19,000, full-length human proteins. Recognizes a protein of ∼55kDa, identified as SOX10. This MAb is highly specific and does not cross-react with other members of the SOX-family. SOX genes comprise a family of genes that are related to the mammalian sex-determining gene SRY. These genes similarly contain sequences that encode for the HMG -box domain, which is responsible for the sequence-specific DNA-binding activity. SOX-10 is a sensitive marker of melanoma, including conventional, spindled, and desmoplastic subtypes. It is expressed by metastatic melanomas and nodal capsular nevus in sentinel lymph nodes, but not by other lymph node components such as dendritic cells, which usually express S100 protein. Commonly used melanoma markers, such as anti-HMB-45 and anti-Melan-A, are poorly expressed in desmoplastic melanomas while SOX-10 is moderately to strongly exp

Content And Storage:
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Isotype:
IgG2b κ

Applications:
Western Blot, Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), SDS-Page

Clone:
SOX10/991

Conjugate:
Unconjugated

Formulation:
10mM PBS with 0.05% BSA with 0.05% Sodium Azide

Gene Symbols:
SOX10

Immunogen:
Recombinant human SOX10 protein fragment (around aa115-269) (exact sequence is proprietar

Purification Method:
Protein A or G purified

Regulatory Status:
RUO

Gene ID (Entrez):
6663

Target Species:
Human, Mouse

Form:
Purified

Img

Novus Biologicals

NBP259621AG

--


Antigen:
SOX10

Classification:
Monoclonal

Concentration:
__

Dilution:
Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Flow (Intracellular)

Gene Alias:
MGC15649, PCWH, SRY (sex determining region Y)-box 10, SRY-related HMG-box gene 10, transcription factor SOX-10, WS4C, WS4mouse, human homolog of

Host Species:
Mouse

Molecular Weight of Antigen:
__

Quantity:
100 μL

Primary or Secondary:
Primary

Test Specificity:
The specificity of this monoclonal antibody to its intended target was validated by HuProtTM Array, containing more than 19,000, full-length human proteins. Recognizes a protein of ∼55kDa, identified as SOX10. This monoclonal antibody is highly specific and does not cross-react with other members of the SOX-family. SOX genes comprise a family of genes that are related to the mammalian sex-determining gene SRY. These genes similarly contain sequences that encode for the HMG-box domain, which is responsible for the sequence-specific DNA-binding activity. SOX-10 is a sensitive marker of melanoma, including conventional, spindled, and desmoplastic subtypes. It is expressed by metastatic melanomas and nodal capsular nevus in sentinel lymph nodes, but not by other lymph node components such as dendritic cells, which usually express S100 protein. Commonly used melanoma markers, such as anti-HMB-45 and anti-Melan-A, are poorly expressed in desmoplastic melanomas while SOX-10 is moderately to strongly expressed in desmoplastic melanomas. SOX-10 is considered as a very reliable marker for recognizing residual desmoplastic melanomas. In normal tissues, it is expressed in Schwann cells, melanocytes, and myoepithelial cells of salivary, bronchial and mammary glands. SOX-10 expression is also observed in mast cells.

Content And Storage:
Store at 4C in the dark.

Isotype:
IgG2b κ

Applications:
Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)

Clone:
SOX10/991

Conjugate:
Alexa Fluor 488

Formulation:
50mM Sodium Borate with 0.05% Sodium Azide

Gene Symbols:
SOX10

Immunogen:
Recombinant human SOX10 protein fragment (around aa115-269) (exact sequence is proprietary) (Uniprot: P56693)

Purification Method:
Protein A or G purified

Regulatory Status:
RUO

Gene ID (Entrez):
6663

Target Species:
Human, Mouse

Form:
Purified

Img

Novus Biologicals

NBP259621AI

--


Antigen:
SOX10

Classification:
Monoclonal

Concentration:
__

Dilution:
Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Flow (Intracellular)

Gene Alias:
MGC15649, PCWH, SRY (sex determining region Y)-box 10, SRY-related HMG-box gene 10, transcription factor SOX-10, WS4C, WS4mouse, human homolog of

Host Species:
Mouse

Molecular Weight of Antigen:
__

Quantity:
100 μL

Primary or Secondary:
Primary

Test Specificity:
The specificity of this monoclonal antibody to its intended target was validated by HuProtTM Array, containing more than 19,000, full-length human proteins. Recognizes a protein of ∼55kDa, identified as SOX10. This monoclonal antibody is highly specific and does not cross-react with other members of the SOX-family. SOX genes comprise a family of genes that are related to the mammalian sex-determining gene SRY. These genes similarly contain sequences that encode for the HMG-box domain, which is responsible for the sequence-specific DNA-binding activity. SOX-10 is a sensitive marker of melanoma, including conventional, spindled, and desmoplastic subtypes. It is expressed by metastatic melanomas and nodal capsular nevus in sentinel lymph nodes, but not by other lymph node components such as dendritic cells, which usually express S100 protein. Commonly used melanoma markers, such as anti-HMB-45 and anti-Melan-A, are poorly expressed in desmoplastic melanomas while SOX-10 is moderately to strongly expressed in desmoplastic melanomas. SOX-10 is considered as a very reliable marker for recognizing residual desmoplastic melanomas. In normal tissues, it is expressed in Schwann cells, melanocytes, and myoepithelial cells of salivary, bronchial and mammary glands. SOX-10 expression is also observed in mast cells.

Content And Storage:
Store at 4C in the dark.

Isotype:
IgG2b κ

Applications:
Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)

Clone:
SOX10/991

Conjugate:
Alexa Fluor 405

Formulation:
50mM Sodium Borate with 0.05% Sodium Azide

Gene Symbols:
SOX10

Immunogen:
Recombinant human SOX10 protein fragment (around aa115-269) (exact sequence is proprietary) (Uniprot: P56693)

Purification Method:
Protein A or G purified

Regulatory Status:
RUO

Gene ID (Entrez):
6663

Target Species:
Human, Mouse

Form:
Purified

Img

Novus Biologicals

NBP259621F

--


Antigen:
SOX10

Classification:
Monoclonal

Concentration:
__

Dilution:
Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Paraffin, Flow (Intracellular)

Gene Alias:
MGC15649, PCWH, SRY (sex determining region Y)-box 10, SRY-related HMG-box gene 10, transcription factor SOX-10, WS4C, WS4mouse, human homolog of

Host Species:
Mouse

Molecular Weight of Antigen:
__

Quantity:
100 μL

Primary or Secondary:
Primary

Test Specificity:
The specificity of this monoclonal antibody to its intended target was validated by HuProtTM Array, containing more than 19,000, full-length human proteins. Recognizes a protein of ∼55kDa, identified as SOX10. This monoclonal antibody is highly specific and does not cross-react with other members of the SOX-family. SOX genes comprise a family of genes that are related to the mammalian sex-determining gene SRY. These genes similarly contain sequences that encode for the HMG-box domain, which is responsible for the sequence-specific DNA-binding activity. SOX-10 is a sensitive marker of melanoma, including conventional, spindled, and desmoplastic subtypes. It is expressed by metastatic melanomas and nodal capsular nevus in sentinel lymph nodes, but not by other lymph node components such as dendritic cells, which usually express S100 protein. Commonly used melanoma markers, such as anti-HMB-45 and anti-Melan-A, are poorly expressed in desmoplastic melanomas while SOX-10 is moderately to strongly expressed in desmoplastic melanomas. SOX-10 is considered as a very reliable marker for recognizing residual desmoplastic melanomas. In normal tissues, it is expressed in Schwann cells, melanocytes, and myoepithelial cells of salivary, bronchial and mammary glands. SOX-10 expression is also observed in mast cells.

Content And Storage:
Store at 4C in the dark.

Isotype:
IgG2b κ

Applications:
Flow Cytometry, Immunohistochemistry, Immunohistochemistry (Paraffin), Immunofluorescence

Clone:
SOX10/991

Conjugate:
FITC

Formulation:
PBS with 0.05% Sodium Azide

Gene Symbols:
SOX10

Immunogen:
Recombinant human SOX10 protein fragment (around aa115-269) (exact sequence is proprietary) (Uniprot: P56693)

Purification Method:
Protein A or G purified

Regulatory Status:
RUO

Gene ID (Entrez):
6663

Target Species:
Human, Mouse

Form:
Purified