Manufacturer: Fischer Scientific
Pack Size | SKU | Availability | Price |
---|---|---|---|
Each of 1 | NBP259620X-Each-of-1 | In Stock | ₹ 46,886.88 |
NBP259620X - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,886.88
GST (18%): ₹ 8,439.638
Total Price: ₹ 55,326.518
SOX10
Monoclonal
0.2 mg/mL
Western Blot 0.5-1 ug/ml, Flow Cytometry 0.5-1 ug/million cells, Immunocytochemistry/Immunofluorescence 1-2 ug/ml, Immunohistochemistry-Paraffin 0.5-1 ug/ml, SDS-Page, Protein Array 1:100-1:2000
MGC15649, PCWH, SRY (sex determining region Y)-box 10, SRY-related HMG-box gene 10, transcription factor SOX-10, WS4C, WS4mouse, human homolog of
Mouse
54 kDa
100 μg
Primary
The specificity of this monoclonal antibody to its intended target was validated by HuProtTM Array, containing more than 19,000, full-length human proteins. Recognizes a protein of ∼55kDa, identified as SOX10. This MAb is highly specific and does not cross-react with other members of the SOX-family. SOX genes comprise a family of genes that are related to the mammalian sex-determining gene SRY. These genes similarly contain sequences that encode for the HMG -box domain, which is responsible for the sequence-specific DNA-binding activity. SOX-10 is a sensitive marker of melanoma, including conventional, spindled, and desmoplastic subtypes. It is expressed by metastatic melanomas and nodal capsular nevus in sentinel lymph nodes, but not by other lymph node components such as dendritic cells, which usually express S100 protein. Commonly used melanoma markers, such as anti-HMB-45 and anti-Melan-A, are poorly expressed in desmoplastic melanomas while SOX-10 is moderately to strongly exp
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
IgG2b κ
Western Blot, Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), SDS-Page
SOX10/991
Unconjugated
10mM PBS with 0.05% BSA with 0.05% Sodium Azide
SOX10
Recombinant human SOX10 protein fragment (around aa115-269) (exact sequence is proprietar
Protein A or G purified
RUO
6663
Human, Mouse
Purified