NBP275772

MyoD Antibody (MYOD1/2075R) - Azide and BSA Free, Novus Biologicals™

Manufacturer: Novus Biologicals

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Pack Size SKU Availability Price
Each of 1 NBP275772-Each-of-1 In Stock ₹ 55,271.76

NBP275772 - Each of 1

₹ 55,271.76

In Stock

Quantity

1

Base Price: ₹ 55,271.76

GST (18%): ₹ 9,948.917

Total Price: ₹ 65,220.677

Antigen

MyoD

Classification

Monoclonal

Concentration

0.2 mg/ml

Dilution

Immunohistochemistry-Paraffin 0.5-1 ug/ml

Gene Accession No.

P15172, P15172

Gene Symbols

MYOD1

Immunogen

Recombinant human full-length MyoD protein (Uniprot: P15172 )

Purification Method

Protein A purified

Research Discipline

Cancer, Cell Cycle and Replication, Growth and Development, Phospho Specific

Gene ID (Entrez)

4654.0

Target Species

Human

Form

Purified

Applications

Immunohistochemistry (Paraffin)

Clone

MYOD1/2075R

Conjugate

Unconjugated

Formulation

10 mM PBS with No Preservative

Gene Alias

bHLHc1BHLHC1, Class C basic helix-loop-helix protein 1, MYF3Myf-3, MYODmyoblast determination protein 1, myogenic differentiation 1, Myogenic factor 3myf-3, PUM

Host Species

Rabbit

Molecular Weight of Antigen

45 kDa

Quantity

100 μg

Primary or Secondary

Primary

Test Specificity

Recognizes a phospho-protein of 45kDa, identified as MyoD1. This monoclonal antibody does not cross react with myogenin, Myf5, or Myf6. Antibody to MyoD1 labels the nuclei of myoblasts in developing muscle tissues. MyoD1 is not detected in normal adult tissue, but is highly expressed in the tumor cell nuclei of rhabdomyosarcomas. Occasionally nuclear expression of MyoD1 is seen in ectomesenchymoma and a subset of Wilm s tumors. Weak cytoplasmic staining is observed in several non-muscle tissues, including glandular epithelium and also in rhabdomyosarcomas, neuroblastomas, Ewing s sarcomas and alveolar soft part sarcomas. Only nuclear staining should be considered as evidence of skeletal muscle differentiation.

Content And Storage

Store at 4°C.

Isotype

IgG

Description

  • MyoD Monoclonal specifically detects MyoD in Human samples
  • It is validated for Immunohistochemistry, Immunohistochemistry-Paraffin, Protein Array.

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Novus Biologicals

NBP275772

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Antigen:
MyoD

Classification:
Monoclonal

Concentration:
0.2 mg/ml

Dilution:
Immunohistochemistry-Paraffin 0.5-1 ug/ml

Gene Accession No.:
P15172, P15172

Gene Symbols:
MYOD1

Immunogen:
Recombinant human full-length MyoD protein (Uniprot: P15172 )

Purification Method:
Protein A purified

Research Discipline:
Cancer, Cell Cycle and Replication, Growth and Development, Phospho Specific

Gene ID (Entrez):
4654.0

Target Species:
Human

Form:
Purified

Applications:
Immunohistochemistry (Paraffin)

Clone:
MYOD1/2075R

Conjugate:
Unconjugated

Formulation:
10 mM PBS with No Preservative

Gene Alias:
bHLHc1BHLHC1, Class C basic helix-loop-helix protein 1, MYF3Myf-3, MYODmyoblast determination protein 1, myogenic differentiation 1, Myogenic factor 3myf-3, PUM

Host Species:
Rabbit

Molecular Weight of Antigen:
45 kDa

Quantity:
100 μg

Primary or Secondary:
Primary

Test Specificity:
Recognizes a phospho-protein of 45kDa, identified as MyoD1. This monoclonal antibody does not cross react with myogenin, Myf5, or Myf6. Antibody to MyoD1 labels the nuclei of myoblasts in developing muscle tissues. MyoD1 is not detected in normal adult tissue, but is highly expressed in the tumor cell nuclei of rhabdomyosarcomas. Occasionally nuclear expression of MyoD1 is seen in ectomesenchymoma and a subset of Wilm s tumors. Weak cytoplasmic staining is observed in several non-muscle tissues, including glandular epithelium and also in rhabdomyosarcomas, neuroblastomas, Ewing s sarcomas and alveolar soft part sarcomas. Only nuclear staining should be considered as evidence of skeletal muscle differentiation.

Content And Storage:
Store at 4°C.

Isotype:
IgG

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Novus Biologicals

NBP275774

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Antigen:
Filaggrin

Classification:
Monoclonal

Concentration:
0.2 mg/ml

Dilution:
Immunohistochemistry-Paraffin 0.5-1 ug/ml

Gene Accession No.:
P20930

Gene Symbols:
FLG

Immunogen:
Recombinant human Filaggrin protein fragment (around aa 998-1104) (exact sequence is proprietary) (Uniprot: P20930)

Purification Method:
Protein A or G purified

Research Discipline:
Cytoskeleton Markers

Gene ID (Entrez):
2312.0

Target Species:
Human

Form:
Purified

Applications:
Immunohistochemistry (Paraffin)

Clone:
FLG/1563

Conjugate:
Unconjugated

Formulation:
10 mM PBS with No Preservative

Gene Alias:
ATOD2, epidermal filaggrin, filaggrin, Profilaggrin

Host Species:
Mouse

Molecular Weight of Antigen:
__

Quantity:
100 μg

Primary or Secondary:
Primary

Test Specificity:
Filaggrin is an intermediate filament-associated protein that aggregates keratin intermediate filaments in mammalian epidermis. It is initially synthesized as a polyprotein precursor, profilaggrin (consisting of multiple filaggrin units of 324 aa each), which is localized in keratohyalin granules, and is subsequently proteolytically processed into individual functional filaggrin molecules. Active filaggrin is present at a level of the epidermis where keratinocytes are in transition between the live nucleated granular layer and the anucleate cornified layer, suggesting that filaggrin aids in the terminal differentiation process by facilitating apoptotic machinery.

Content And Storage:
Store at 4°C.

Isotype:
IgG2b κ

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Novus Biologicals

NBP275775

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Antigen:
UCH-L1/PGP9.5

Classification:
Monoclonal

Concentration:
0.2 mg/ml

Dilution:
Western Blot 0.5-1 ug/ml, Immunohistochemistry-Paraffin 1-2 ug/ml

Gene Accession No.:
P09936

Gene Symbols:
UCHL1

Immunogen:
Recombinant full-length human UCH-L1/PGP9.5 protein (Uniprot: P09936)

Purification Method:
Protein A or G purified

Research Discipline:
__

Gene ID (Entrez):
7345.0

Target Species:
Human, Rat

Form:
Purified

Applications:
Western Blot, Immunohistochemistry (Paraffin)

Clone:
rUCHL1/775

Conjugate:
Unconjugated

Formulation:
10 mM PBS with No Preservative

Gene Alias:
EC 3.4.19.12, EC 6.-, Neuron cytoplasmic protein 9.5, PARK5, PGP 9.5, PGP9.5, PGP9.5Uch-L1, PGP95, ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase), ubiquitin carboxyl-terminal hydrolase isozyme L1, ubiquitin C-terminal hydrolase, Ubiquitin thioesterase L1, UCHL1, UCH-L1

Host Species:
Mouse

Molecular Weight of Antigen:
__

Quantity:
100 μg

Primary or Secondary:
Primary

Test Specificity:
This MAb reacts with a protein of 20-30 kDa, identified as PGP9.5, also known as ubiquitin carboxyl-terminal hydrolase-1 (UCH-L1). Initially, PGP9.5 expression in normal tissues was reported in neurons and neuroendocrine cells but later it was found in distal renal tubular epithelium, spermatogonia, Leydig cells, oocytes, melanocytes, prostatic secretory epithelium, ejaculatory duct cells, epididymis, mammary epithelial cells, Merkel cells, and dermal fibroblasts. Furthermore, immunostaining for PGP9.5 has been shown in a wide variety of mesenchymal neoplasms as well. A mutation in PGP9.5 gene is believed to cause a form of Parkinson's disease.

Content And Storage:
Store at 4°C.

Isotype:
IgG1 κ

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Novus Biologicals

NBP275777

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Antigen:
Prostatic Acid Phosphatase/ACPP

Classification:
Monoclonal

Concentration:
0.2 mg/ml

Dilution:
Immunohistochemistry-Paraffin 0.5-1.0 ug/ml

Gene Accession No.:
P15309

Gene Symbols:
ACP3

Immunogen:
Recombinant full-length human Prostatic Acid Phosphatase/ACPP protein (Uniprot: P15309)

Purification Method:
Protein A or G purified

Research Discipline:
Cell Cycle and Replication

Gene ID (Entrez):
55.0

Target Species:
Human

Form:
Purified

Applications:
Immunohistochemistry (Paraffin)

Clone:
rACPP/1338

Conjugate:
Unconjugated

Formulation:
10 mM PBS with No Preservative

Gene Alias:
acid phosphatase, prostate, ACP3, ACP-3, EC 3.1.3.2, PAP, prostatic acid phosphatase, prostatic acid phosphotase

Host Species:
Mouse

Molecular Weight of Antigen:
52 kDa

Quantity:
100 μg

Primary or Secondary:
Primary

Test Specificity:
Recognizes a protein of 52kDa, identified as prostate specific acid phosphatase (PSAP). This enzyme catalyzes the conversion of orthophosphoric monoester to alcohol and orthophosphate. It is synthesized under androgen regulation and is secreted by the epithelial cells of the prostate gland. PSAP is found in non-neoplastic adult and fetal prostatic glands, primary and metastatic prostatic carcinomas. It shows no staining in granulocytes, osteoclasts, parietal cells of the stomach, liver cells, renal cell or breast carcinomas.

Content And Storage:
Store at 4°C.

Isotype:
IgG1 κ