NE1019100UL
MilliporeSigma™ anti-Myelin Basic Protein Clone: SMI-99,
Manufacturer: MilliporeSigma™
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | NE1019100UL-Each-of-1 | In Stock | ₹ 50,097.09 |
NE1019100UL - Each of 1
In Stock
Quantity
1
Base Price: ₹ 50,097.09
GST (18%): ₹ 9,017.476
Total Price: ₹ 59,114.566
Antigen
Myelin Basic Protein
Classification
Monoclonal
Conjugate
Unconjugated
Host Species
Mouse
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Guinea Pig
Form
Purified
Applications
ELISA, Immunoblot, Immunoblot, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin)
Clone
SMI-99
Formulation
In PBS.
Immunogen
human myelin basic protein
Regulatory Status
RUO
Test Specificity
Recognizes the ∽21kDa myelin basic protein in rat brain tissue. Does not recognize the 14kDa form. Recognizes most mammalian species.
Content And Storage
−20°C
Isotype
IgG2b
Related Products
Description
- Specifically detects Myelin Basic Protein Clone: SMI-99 in Guinea Pig samples, and it is validated for ELISA, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immuno Blotting The myelin sheath is essential for rapid and effective propagation of action potential within the axon
- Mutations identified in several myelin-related genes reportedly lead to severe demyelinating neuropathies
- Recent evidence also suggests that the autoimmune disease Multiple Sclerosis (MS) is mediated by T cells with specificity for antigens in the myelin sheath
- Although myelin in the central nervous system (CNS) and peripheral nervous system (PNS) is structurally similar, it is chemically distinct since oligodendrocytes form myelin in the CNS whereas Schwann cells generate PNS myelin
- Myelin proteolipid protein (PLP) is the predominant integral membrane protein in mammalian CNS myelin
- In contrast, myelin basic protein (MBP) is localized to the myelin cytoplasm and is highly conserved among species
- Both MBP and PLP mediate myelin compaction, whereas thickness is regulated by MBP
- Several other myelin proteins have been identified to play distinct or partially overlapping functions in the formation and maintenance of the myelin sheath, including P0, myelin-associated glycoprotein (MAG), peripheral myelin protein (PMP22), and Connexin 32 (Cx32)
- The development of the myelin sheath has been a good model for understanding the mechanisms of neuron-glia interaction.
Compare Similar Items
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Antigen: Myelin Basic Protein
Classification: Monoclonal
Conjugate: Unconjugated
Host Species: Mouse
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Guinea Pig
Form: Purified
Applications: ELISA, Immunoblot, Immunoblot, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin)
Clone: SMI-99
Formulation: In PBS.
Immunogen: human myelin basic protein
Regulatory Status: RUO
Test Specificity: Recognizes the ∽21kDa myelin basic protein in rat brain tissue. Does not recognize the 14kDa form. Recognizes most mammalian species.
Content And Storage: −20°C
Isotype: IgG2b
Antigen:
Myelin Basic Protein
Classification:
Monoclonal
Conjugate:
Unconjugated
Host Species:
Mouse
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Guinea Pig
Form:
Purified
Applications:
ELISA, Immunoblot, Immunoblot, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin)
Clone:
SMI-99
Formulation:
In PBS.
Immunogen:
human myelin basic protein
Regulatory Status:
RUO
Test Specificity:
Recognizes the ∽21kDa myelin basic protein in rat brain tissue. Does not recognize the 14kDa form. Recognizes most mammalian species.
Content And Storage:
−20°C
Isotype:
IgG2b
Antigen: Neurofilament H
Classification: Monoclonal
Conjugate: Unconjugated
Host Species: Mouse
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Chicken, Xenopus species
Form: __
Applications: ELISA, Immunoblot, Immunoblot, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin)
Clone: SMI-31
Formulation: Undiluted ascites.
Immunogen: homogenized, hypothalami from Fischer 344 rat brain
Regulatory Status: RUO
Test Specificity: Recognizes the ∽180-200kDa phosphorylated neurofilament H protein in rat central nervous system (CNS) cytoskeletal preparations. Also weakly recognizes phosphorylated NF-M protein.
Content And Storage: −20°C
Isotype: IgG1
Antigen:
Neurofilament H
Classification:
Monoclonal
Conjugate:
Unconjugated
Host Species:
Mouse
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Chicken, Xenopus species
Form:
__
Applications:
ELISA, Immunoblot, Immunoblot, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin)
Clone:
SMI-31
Formulation:
Undiluted ascites.
Immunogen:
homogenized, hypothalami from Fischer 344 rat brain
Regulatory Status:
RUO
Test Specificity:
Recognizes the ∽180-200kDa phosphorylated neurofilament H protein in rat central nervous system (CNS) cytoskeletal preparations. Also weakly recognizes phosphorylated NF-M protein.
Content And Storage:
−20°C
Isotype:
IgG1
Antigen: APOC1
Classification: Monoclonal
Conjugate: Unconjugated
Host Species: Mouse
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Form: Purified
Applications: ELISA, Immunoblot, Immunoblot
Clone: 2E2-1A3
Formulation: In PBS, pH 7.2.
Immunogen: A recombinant polypeptide corresponding to amino acids 1-84 of human APOC1, expressed as a GST fusion protein
Regulatory Status: RUO
Test Specificity: Recognizes the ∽10kDa APOC1 protein in human liver tissue.
Content And Storage: −20°C
Isotype: IgG1
Antigen:
APOC1
Classification:
Monoclonal
Conjugate:
Unconjugated
Host Species:
Mouse
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Form:
Purified
Applications:
ELISA, Immunoblot, Immunoblot
Clone:
2E2-1A3
Formulation:
In PBS, pH 7.2.
Immunogen:
A recombinant polypeptide corresponding to amino acids 1-84 of human APOC1, expressed as a GST fusion protein
Regulatory Status:
RUO
Test Specificity:
Recognizes the ∽10kDa APOC1 protein in human liver tissue.
Content And Storage:
−20°C
Isotype:
IgG1
Antigen: __
Classification: __
Conjugate: __
Host Species: __
Quantity: 1 Ea.
Primary or Secondary: __
Target Species: __
Form: __
Applications: __
Clone: __
Formulation: __
Immunogen: __
Regulatory Status: __
Test Specificity: __
Content And Storage: • Neon™ NxT electroporation device• 1-channel pipette• 8-channel pipette• 1-channel pipette station• 8-channel pipette station• 8-channel software activation (pre-installed)• Power cord• Quick reference guides
Isotype: __
Antigen:
__
Classification:
__
Conjugate:
__
Host Species:
__
Quantity:
1 Ea.
Primary or Secondary:
__
Target Species:
__
Form:
__
Applications:
__
Clone:
__
Formulation:
__
Immunogen:
__
Regulatory Status:
__
Test Specificity:
__
Content And Storage:
• Neon™ NxT electroporation device• 1-channel pipette• 8-channel pipette• 1-channel pipette station• 8-channel pipette station• 8-channel software activation (pre-installed)• Power cord• Quick reference guides
Isotype:
__