NE1022100UL

MilliporeSigma™ anti-PhosphoDetect Neurofilament H Clone: SMI-31,

Manufacturer: MilliporeSigma™

Select a Size

Pack Size SKU Availability Price
Each of 1 NE1022100UL-Each-of-1 In Stock ₹ 54,635.19

NE1022100UL - Each of 1

₹ 54,635.19

In Stock

Quantity

1

Base Price: ₹ 54,635.19

GST (18%): ₹ 9,834.334

Total Price: ₹ 64,469.524

Antigen

Neurofilament H

Classification

Monoclonal

Conjugate

Unconjugated

Host Species

Mouse

Purification Method

Unpurified

Regulatory Status

RUO

Test Specificity

Recognizes the ∽180-200kDa phosphorylated neurofilament H protein in rat central nervous system (CNS) cytoskeletal preparations. Also weakly recognizes phosphorylated NF-M protein.

Content And Storage

−20°C

Applications

ELISA, Immunoblot, Immunoblot, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin)

Clone

SMI-31

Formulation

Undiluted ascites.

Immunogen

homogenized, hypothalami from Fischer 344 rat brain

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Chicken, Xenopus species

Isotype

IgG1

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Description

  • Specifically detects Neurofilament H Clone: SMI-31 in Chicken, Xenopus samples, and it is validated for ELISA, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immuno Blotting Neurofilaments are a type of intermediate filament that serve as major constituent of the cytoskeleton of axons
  • They are the most abundant fibrillar components of the axon and are composed of three intertwined protofibrils
  • The neurofilament triplet proteins (NF-L, 68/70kDa; NF-M, 160kDa; and NF-H, 200kDa) are found in both the central and peripheral nervous system and are usually neuron-specific
  • NF-H and NF-M both require the presence of NF-L protein to co-assemble
  • NF-H and NF-M become highly phosphorylated after newly formed neurofilaments enter the axon
  • Neurofilament staining is observed in neuromas, ganglioneuromas, gangliogliomas, ganglioneuroblastomas and neuroblastomas, and have also been detected in paragangliomas and adrenal and extra-adrenal pheochromocytomas
  • Carcinoids, neuroendocrine carcinomas of the skin, and oat cell carcinomas of the lung are also known to express neurofilaments.

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MilliporeSigma™

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Antigen:
Neurofilament H

Classification:
Monoclonal

Conjugate:
Unconjugated

Host Species:
Mouse

Purification Method:
Unpurified

Regulatory Status:
RUO

Test Specificity:
Recognizes the ∽180-200kDa phosphorylated neurofilament H protein in rat central nervous system (CNS) cytoskeletal preparations. Also weakly recognizes phosphorylated NF-M protein.

Content And Storage:
−20°C

Applications:
ELISA, Immunoblot, Immunoblot, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin)

Clone:
SMI-31

Formulation:
Undiluted ascites.

Immunogen:
homogenized, hypothalami from Fischer 344 rat brain

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Chicken, Xenopus species

Isotype:
IgG1

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Antigen:
APOC1

Classification:
Monoclonal

Conjugate:
Unconjugated

Host Species:
Mouse

Purification Method:
__

Regulatory Status:
RUO

Test Specificity:
Recognizes the ∽10kDa APOC1 protein in human liver tissue.

Content And Storage:
−20°C

Applications:
ELISA, Immunoblot, Immunoblot

Clone:
2E2-1A3

Formulation:
In PBS, pH 7.2.

Immunogen:
A recombinant polypeptide corresponding to amino acids 1-84 of human APOC1, expressed as a GST fusion protein

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Isotype:
IgG1

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Host Species:
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Target Species:
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