OP03L100UG
MilliporeSigma™ anti-p53 (Pantropic) Clone: PAb421,
Manufacturer: MilliporeSigma™
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | OP03L100UG-Each-of-1 | In Stock | ₹ 44,990.87 |
OP03L100UG - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,990.87
GST (18%): ₹ 8,098.357
Total Price: ₹ 53,089.227
Antigen
p53 (Pantropic)
Classification
Monoclonal
Conjugate
Unconjugated
Host Species
Mouse
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human, Monkey, Mouse, Rabbit, Rat
Form
Purified
Applications
Flow Cytometry, Gel Supershift, Immunoblot, Immunoblot, Immunofluorescence, Immunohistochemistry (Frozen), Immunoprecipitation
Clone
PAb421
Formulation
In 50mM sodium phosphate buffer, 0.2% gelatin, pH 7.5.
Immunogen
partially purified mouse p53
Regulatory Status
RUO
Test Specificity
Recognizes the ∽53kDa mammalian wild-type and mutant p53 protein. Does not recognize phosphorylated or acetylated p53.
Content And Storage
2°C to 8°C
Isotype
IgG2a
Related Products
Description
- Specifically detects p53 (Pantropic) Clone: PAb421 in Human, Monkey, Mouse, Rabbit, Rat samples, and it is validated for Flow Cytometry, Gel Supershift, Immunofluorescence, Immunohistochemistry (Frozen), Immunoprecipitation, Immuno Blotting The human p53 tumor suppressor gene encodes a 393 amino acid phosphoprotein that exhibits sequence-specific DNA binding and directly interacts with various cellular and viral proteins
- p53 is the most commonly mutated gene in human cancer, with the majority of the mutations being amino acid substitutions
- The normal function of p53 is to effect cell cycle arrest at the G1 and G2 checkpoints in response to DNA damage
- This checkpoint function is executed by accumulation of p53 followed by induction of the GADD45, WAF1 and MDM2 genes
- The current model of p53 function postulates that p53 senses DNA damage and arrests the cell cycle in either the G1 or G2 phases to allow DNA repair to take place
- If repair is not successful, p53 initiates programmed cell death, thus preventing the propagation of genetic defects to successive generations of cells.
Compare Similar Items
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Antigen: p53 (Pantropic)
Classification: Monoclonal
Conjugate: Unconjugated
Host Species: Mouse
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Monkey, Mouse, Rabbit, Rat
Form: Purified
Applications: Flow Cytometry, Gel Supershift, Immunoblot, Immunoblot, Immunofluorescence, Immunohistochemistry (Frozen), Immunoprecipitation
Clone: PAb421
Formulation: In 50mM sodium phosphate buffer, 0.2% gelatin, pH 7.5.
Immunogen: partially purified mouse p53
Regulatory Status: RUO
Test Specificity: Recognizes the ∽53kDa mammalian wild-type and mutant p53 protein. Does not recognize phosphorylated or acetylated p53.
Content And Storage: 2°C to 8°C
Isotype: IgG2a
Antigen:
p53 (Pantropic)
Classification:
Monoclonal
Conjugate:
Unconjugated
Host Species:
Mouse
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Monkey, Mouse, Rabbit, Rat
Form:
Purified
Applications:
Flow Cytometry, Gel Supershift, Immunoblot, Immunoblot, Immunofluorescence, Immunohistochemistry (Frozen), Immunoprecipitation
Clone:
PAb421
Formulation:
In 50mM sodium phosphate buffer, 0.2% gelatin, pH 7.5.
Immunogen:
partially purified mouse p53
Regulatory Status:
RUO
Test Specificity:
Recognizes the ∽53kDa mammalian wild-type and mutant p53 protein. Does not recognize phosphorylated or acetylated p53.
Content And Storage:
2°C to 8°C
Isotype:
IgG2a
Antigen: v-Src
Classification: Monoclonal
Conjugate: Unconjugated
Host Species: Mouse
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Form: Liquid
Applications: Immunohistochemistry, Western Blot
Clone: 327
Formulation: In 50mM sodium phosphate buffer, 0.2% gelatin, pH 7.4, ≤0.1% Sodium Azide.
Immunogen: purified v-Src
Regulatory Status: RUO
Test Specificity: __
Content And Storage: 2°-8°C
Isotype: IgG1
Antigen:
v-Src
Classification:
Monoclonal
Conjugate:
Unconjugated
Host Species:
Mouse
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Form:
Liquid
Applications:
Immunohistochemistry, Western Blot
Clone:
327
Formulation:
In 50mM sodium phosphate buffer, 0.2% gelatin, pH 7.4, ≤0.1% Sodium Azide.
Immunogen:
purified v-Src
Regulatory Status:
RUO
Test Specificity:
__
Content And Storage:
2°-8°C
Isotype:
IgG1
Antigen: p53 (Ab-11) (Pantropic)
Classification: Monoclonal
Conjugate: Unconjugated
Host Species: Mouse
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Mouse
Form: Purified
Applications: Immunoprecipitation
Clone: PAb1802
Formulation: Lyophilized from a volatile buffer, 100μg BSA.
Immunogen: recombinant, human p53 protein
Regulatory Status: RUO
Test Specificity: Recognizes the ∽53kDa wild-type and mutant p53 protein in immunoblotting. Recognizes only the wild-type p53 protein in immunoprecipitation.
Content And Storage: 2°C to 8°C
Isotype: IgG1
Antigen:
p53 (Ab-11) (Pantropic)
Classification:
Monoclonal
Conjugate:
Unconjugated
Host Species:
Mouse
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Form:
Purified
Applications:
Immunoprecipitation
Clone:
PAb1802
Formulation:
Lyophilized from a volatile buffer, 100μg BSA.
Immunogen:
recombinant, human p53 protein
Regulatory Status:
RUO
Test Specificity:
Recognizes the ∽53kDa wild-type and mutant p53 protein in immunoblotting. Recognizes only the wild-type p53 protein in immunoprecipitation.
Content And Storage:
2°C to 8°C
Isotype:
IgG1
Antigen: c-Myc
Classification: Monoclonal
Conjugate: Unconjugated
Host Species: Mouse
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Form: Liquid
Applications: Flow Cytometry, Immunoblot, Immunoblot, Immunofluorescence, Immunohistochemistry (Frozen), Immunoprecipitation
Clone: 90000000000
Formulation: In 0.05M sodium phosphate buffer, 0.2% gelatin.
Immunogen: a synthetic peptide (AEEQKLISEEDLLRKRREQLKHKLEQLRNSCA) corresponding to amino acids 408-439 of human c-Myc
Regulatory Status: RUO
Test Specificity: Recognizes the ∽60-67kDa c-Myc protein in HL60 cells and lung carcinoma tissue.
Content And Storage: 2°C to 8°C
Isotype: IgG1
Antigen:
c-Myc
Classification:
Monoclonal
Conjugate:
Unconjugated
Host Species:
Mouse
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Form:
Liquid
Applications:
Flow Cytometry, Immunoblot, Immunoblot, Immunofluorescence, Immunohistochemistry (Frozen), Immunoprecipitation
Clone:
90000000000
Formulation:
In 0.05M sodium phosphate buffer, 0.2% gelatin.
Immunogen:
a synthetic peptide (AEEQKLISEEDLLRKRREQLKHKLEQLRNSCA) corresponding to amino acids 408-439 of human c-Myc
Regulatory Status:
RUO
Test Specificity:
Recognizes the ∽60-67kDa c-Myc protein in HL60 cells and lung carcinoma tissue.
Content And Storage:
2°C to 8°C
Isotype:
IgG1