OP92100UG
MilliporeSigma™ anti-BRCA1 Clone: MS110,
Manufacturer: MilliporeSigma™
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | OP92100UG-Each-of-1 | In Stock | ₹ 45,381.02 |
OP92100UG - Each of 1
In Stock
Quantity
1
Base Price: ₹ 45,381.02
GST (18%): ₹ 8,168.584
Total Price: ₹ 53,549.604
Antigen
BRCA1
Classification
Monoclonal
Conjugate
Unconjugated
Host Species
Mouse
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human
Form
Purified
Applications
Immunoblot, Immunofluorescence, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation
Clone
MS110
Formulation
In 50mM sodium phosphate buffer, 0.2% gelatin, pH 7.5.
Immunogen
recombinant human BRCA1
Regulatory Status
RUO
Test Specificity
Recognizes the ∽220kDa BRCA1 protein in MCF-7 cells. Does not cross-react with blood group antigens or growth factor receptors such as EGFR. Sold under license of U.S. Patent 5,753,441 and 6,162,897.
Content And Storage
2°C to 8°C
Isotype
IgG1
Related Products
Description
- Specifically detects BRCA1 Clone: MS110 in Human samples, and it is validated for Immunofluorescence, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation, Immuno Blotting Inactivation of the BRCA1 gene, located at 17q21, is responsible for some forms of familial breast and ovarian cancer and sporadic ovarian cancer
- BRCA1 encodes a protein of 1863 amino acids with an amino-terminal domain that exhibits similarity to the zinc-ring domain found in several regulatory and transcription factors
- Mutations that disrupt this domain are some of the most frequently occurring ones linked to breast and ovarian cancer
- Inhibition of BRCA1 expression leads to accelerated growth of mammary cells in vitro while loss of expression is observed during progression from benign disease to metastatic breast cancer suggesting that BRCA1 serves as a negative growth regulator
- The ∽220kDa BRCA1 protein is expressed predominantly in the nucleus and appears to undergo cell cycle regulation with mRNA expression induced prior to DNA synthesis.
Compare Similar Items
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Antigen: BRCA1
Classification: Monoclonal
Conjugate: Unconjugated
Host Species: Mouse
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Form: Purified
Applications: Immunoblot, Immunofluorescence, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation
Clone: MS110
Formulation: In 50mM sodium phosphate buffer, 0.2% gelatin, pH 7.5.
Immunogen: recombinant human BRCA1
Regulatory Status: RUO
Test Specificity: Recognizes the ∽220kDa BRCA1 protein in MCF-7 cells. Does not cross-react with blood group antigens or growth factor receptors such as EGFR. Sold under license of U.S. Patent 5,753,441 and 6,162,897.
Content And Storage: 2°C to 8°C
Isotype: IgG1
Antigen:
BRCA1
Classification:
Monoclonal
Conjugate:
Unconjugated
Host Species:
Mouse
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Form:
Purified
Applications:
Immunoblot, Immunofluorescence, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation
Clone:
MS110
Formulation:
In 50mM sodium phosphate buffer, 0.2% gelatin, pH 7.5.
Immunogen:
recombinant human BRCA1
Regulatory Status:
RUO
Test Specificity:
Recognizes the ∽220kDa BRCA1 protein in MCF-7 cells. Does not cross-react with blood group antigens or growth factor receptors such as EGFR. Sold under license of U.S. Patent 5,753,441 and 6,162,897.
Content And Storage:
2°C to 8°C
Isotype:
IgG1
Antigen: BRCA1
Classification: Monoclonal
Conjugate: Unconjugated
Host Species: Mouse
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Form: Purified
Applications: Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation
Clone: MS13
Formulation: In 0.05M sodium phosphate buffer, 0.2% gelatin.
Immunogen: recombinant, human BRCA1
Regulatory Status: RUO
Test Specificity: Recognizes the ∽220kDa BRCA1 protein in MCF-7 cells. Does not react with blood group antigens or growth factor receptors such as EGFR. Sold under license of U.S. Patent 5,753,441 and 6,162,897.
Content And Storage: 2°C to 8°C
Isotype: IgG1
Antigen:
BRCA1
Classification:
Monoclonal
Conjugate:
Unconjugated
Host Species:
Mouse
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Form:
Purified
Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation
Clone:
MS13
Formulation:
In 0.05M sodium phosphate buffer, 0.2% gelatin.
Immunogen:
recombinant, human BRCA1
Regulatory Status:
RUO
Test Specificity:
Recognizes the ∽220kDa BRCA1 protein in MCF-7 cells. Does not react with blood group antigens or growth factor receptors such as EGFR. Sold under license of U.S. Patent 5,753,441 and 6,162,897.
Content And Storage:
2°C to 8°C
Isotype:
IgG1
Antigen: BRCA2
Classification: Monoclonal
Conjugate: Unconjugated
Host Species: Mouse
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Form: Purified
Applications: Immunoprecipitation
Clone: 2B
Formulation: In PBS.
Immunogen: a recombinant protein consisting of amino acids 1651-1821 of human BRCA2 fused to GST
Regulatory Status: RUO
Test Specificity: Recognzies the ∽460kDa BRCA2 protein in cells expressing a wild type BRCA2 gene. Sold under license of U.S. Patent 5,753,441 and 6,162,897.
Content And Storage: −20°C
Isotype: IgG2b
Antigen:
BRCA2
Classification:
Monoclonal
Conjugate:
Unconjugated
Host Species:
Mouse
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Form:
Purified
Applications:
Immunoprecipitation
Clone:
2B
Formulation:
In PBS.
Immunogen:
a recombinant protein consisting of amino acids 1651-1821 of human BRCA2 fused to GST
Regulatory Status:
RUO
Test Specificity:
Recognzies the ∽460kDa BRCA2 protein in cells expressing a wild type BRCA2 gene. Sold under license of U.S. Patent 5,753,441 and 6,162,897.
Content And Storage:
−20°C
Isotype:
IgG2b
Antigen: STAT5 alpha/beta
Classification: Polyclonal
Conjugate: Unconjugated
Host Species: Rabbit
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Hamster, Human, Mouse
Form: Liquid
Applications: Western Blot
Clone: __
Formulation: Dulbecco′s PBS with 1mg/mL BSA, 50% glycerol and 0.05% sodium azide; pH 7.3
Immunogen: Synthetic Peptide derived from an internal region of human STAT5.
Regulatory Status: RUO
Test Specificity: __
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Isotype: IgG
Antigen:
STAT5 alpha/beta
Classification:
Polyclonal
Conjugate:
Unconjugated
Host Species:
Rabbit
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Hamster, Human, Mouse
Form:
Liquid
Applications:
Western Blot
Clone:
__
Formulation:
Dulbecco′s PBS with 1mg/mL BSA, 50% glycerol and 0.05% sodium azide; pH 7.3
Immunogen:
Synthetic Peptide derived from an internal region of human STAT5.
Regulatory Status:
RUO
Test Specificity:
__
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Isotype:
IgG