OP104L100UG
MilliporeSigma™ anti-p53 (Pantropic) Clone: PAb1802,
Manufacturer: MilliporeSigma™
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | OP104L100UG-Each-of-1 | In Stock | ₹ 46,364.96 |
OP104L100UG - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,364.96
GST (18%): ₹ 8,345.693
Total Price: ₹ 54,710.653
Antigen
p53 (Ab-11) (Pantropic)
Classification
Monoclonal
Conjugate
Unconjugated
Host Species
Mouse
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human, Mouse
Form
Purified
Applications
Immunoprecipitation
Clone
PAb1802
Formulation
Lyophilized from a volatile buffer, 100μg BSA.
Immunogen
recombinant, human p53 protein
Regulatory Status
RUO
Test Specificity
Recognizes the ∽53kDa wild-type and mutant p53 protein in immunoblotting. Recognizes only the wild-type p53 protein in immunoprecipitation.
Content And Storage
2°C to 8°C
Isotype
IgG1
Related Products
Description
- Specifically detects p53 (Ab-11) (Pantropic) Clone: PAb1802 in Human, Mouse samples, and it is validated for Immunoprecipitation p53 (393 amino acids) exhibits sequence-specific DNA binding, directly interacts with various cellular and viral proteins, and induces cell cycle arrest in response to DNA damage by inducing GADD45, WAF1, and MDM2
- p53 is the most commonly mutated gene in human cancer with most mutations occurring in the DNA contact residues
- p53 binds damaged DNA non-specifically via its C-terminal 75 amino acids which in turn may be responsible for subsequent activation, sequence-specific DNA binding, and WAF1 induction allowing DNA repair to take place
- p53 down regulates bcl-2 expression and up regulates bax expression, but may not always be necessary for apoptosis
- In addition to the afore mentioned proteins, two other proteins involved in replication and recombination, RPA and RAD51, also bind p53.
Compare Similar Items
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Antigen: p53 (Ab-11) (Pantropic)
Classification: Monoclonal
Conjugate: Unconjugated
Host Species: Mouse
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Mouse
Form: Purified
Applications: Immunoprecipitation
Clone: PAb1802
Formulation: Lyophilized from a volatile buffer, 100μg BSA.
Immunogen: recombinant, human p53 protein
Regulatory Status: RUO
Test Specificity: Recognizes the ∽53kDa wild-type and mutant p53 protein in immunoblotting. Recognizes only the wild-type p53 protein in immunoprecipitation.
Content And Storage: 2°C to 8°C
Isotype: IgG1
Antigen:
p53 (Ab-11) (Pantropic)
Classification:
Monoclonal
Conjugate:
Unconjugated
Host Species:
Mouse
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Form:
Purified
Applications:
Immunoprecipitation
Clone:
PAb1802
Formulation:
Lyophilized from a volatile buffer, 100μg BSA.
Immunogen:
recombinant, human p53 protein
Regulatory Status:
RUO
Test Specificity:
Recognizes the ∽53kDa wild-type and mutant p53 protein in immunoblotting. Recognizes only the wild-type p53 protein in immunoprecipitation.
Content And Storage:
2°C to 8°C
Isotype:
IgG1
Antigen: c-Myc
Classification: Monoclonal
Conjugate: Unconjugated
Host Species: Mouse
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Form: Liquid
Applications: Flow Cytometry, Immunoblot, Immunoblot, Immunofluorescence, Immunohistochemistry (Frozen), Immunoprecipitation
Clone: 90000000000
Formulation: In 0.05M sodium phosphate buffer, 0.2% gelatin.
Immunogen: a synthetic peptide (AEEQKLISEEDLLRKRREQLKHKLEQLRNSCA) corresponding to amino acids 408-439 of human c-Myc
Regulatory Status: RUO
Test Specificity: Recognizes the ∽60-67kDa c-Myc protein in HL60 cells and lung carcinoma tissue.
Content And Storage: 2°C to 8°C
Isotype: IgG1
Antigen:
c-Myc
Classification:
Monoclonal
Conjugate:
Unconjugated
Host Species:
Mouse
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Form:
Liquid
Applications:
Flow Cytometry, Immunoblot, Immunoblot, Immunofluorescence, Immunohistochemistry (Frozen), Immunoprecipitation
Clone:
90000000000
Formulation:
In 0.05M sodium phosphate buffer, 0.2% gelatin.
Immunogen:
a synthetic peptide (AEEQKLISEEDLLRKRREQLKHKLEQLRNSCA) corresponding to amino acids 408-439 of human c-Myc
Regulatory Status:
RUO
Test Specificity:
Recognizes the ∽60-67kDa c-Myc protein in HL60 cells and lung carcinoma tissue.
Content And Storage:
2°C to 8°C
Isotype:
IgG1
Antigen: c-Myc
Classification: Monoclonal
Conjugate: Unconjugated
Host Species: Mouse
Quantity: 200 μg
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Form: Lyophilized
Applications: Flow Cytometry, Immunoblot, Immunoblot, Immunofluorescence, Immunohistochemistry (Frozen), Immunoprecipitation
Clone: 90000000000
Formulation: Lyophilized from a volatile buffer, 100μg BSA.
Immunogen: a synthetic peptide (AEEQKLISEEDLLRKRREQLKHKLEQLRNSCA) corresponding to amino acids 408-439 of human c-Myc
Regulatory Status: RUO
Test Specificity: Recognizes a ∽60-67kDa c-Myc protein in HL60 cells and lung carcinoma tissue.
Content And Storage: 2°C to 8°C
Isotype: IgG1
Antigen:
c-Myc
Classification:
Monoclonal
Conjugate:
Unconjugated
Host Species:
Mouse
Quantity:
200 μg
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Form:
Lyophilized
Applications:
Flow Cytometry, Immunoblot, Immunoblot, Immunofluorescence, Immunohistochemistry (Frozen), Immunoprecipitation
Clone:
90000000000
Formulation:
Lyophilized from a volatile buffer, 100μg BSA.
Immunogen:
a synthetic peptide (AEEQKLISEEDLLRKRREQLKHKLEQLRNSCA) corresponding to amino acids 408-439 of human c-Myc
Regulatory Status:
RUO
Test Specificity:
Recognizes a ∽60-67kDa c-Myc protein in HL60 cells and lung carcinoma tissue.
Content And Storage:
2°C to 8°C
Isotype:
IgG1
Antigen: c-ErbB3
Classification: Monoclonal
Conjugate: Unconjugated
Host Species: Mouse
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Form: Purified
Applications: Flow Cytometry, Immunofluorescence, Immunoprecipitation
Clone: H3.90.6 or Ab90
Formulation: In 10mM PBS, pH 7.4.
Immunogen: recombinant, human ErbB3 extracellular domain
Regulatory Status: RUO
Test Specificity: Recognizes the ∽185kDa c-ErbB3/HER3 protein in T47D cells and breast carcinoma tissue.
Content And Storage: −20°C
Isotype: IgG2a
Antigen:
c-ErbB3
Classification:
Monoclonal
Conjugate:
Unconjugated
Host Species:
Mouse
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Form:
Purified
Applications:
Flow Cytometry, Immunofluorescence, Immunoprecipitation
Clone:
H3.90.6 or Ab90
Formulation:
In 10mM PBS, pH 7.4.
Immunogen:
recombinant, human ErbB3 extracellular domain
Regulatory Status:
RUO
Test Specificity:
Recognizes the ∽185kDa c-ErbB3/HER3 protein in T47D cells and breast carcinoma tissue.
Content And Storage:
−20°C
Isotype:
IgG2a