OP43L100UG
MilliporeSigma™ anti-p53 (Pantropic) Clone: DO-1,
Manufacturer: MilliporeSigma™
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | OP43L100UG-Each-of-1 | In Stock | ₹ 49,830.14 |
OP43L100UG - Each of 1
In Stock
Quantity
1
Base Price: ₹ 49,830.14
GST (18%): ₹ 8,969.425
Total Price: ₹ 58,799.565
Antigen
p53 (Pantropic)
Classification
Monoclonal
Conjugate
Unconjugated
Host Species
Mouse
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Feline, Human
Form
Purified
Applications
Immunoblot, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation
Clone
DO-1
Formulation
In 0.05M sodium phosphate buffer, 0.2% gelatin.
Immunogen
wild type, recombinant, human p53
Regulatory Status
RUO
Test Specificity
Recognizes the ∽53kDa wild-type and mutant p53 protein in A431 cells and breast carcinoma tissue.
Content And Storage
2°C to 8°C
Isotype
IgG2a
Related Products
Description
- Specifically detects p53 (Pantropic) Clone: DO-1 in Feline, Human samples, and it is validated for Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation, Immuno Blotting The human p53 tumor suppressor gene encodes a 393 amino acid phosphoprotein that exhibits sequence-specific DNA binding and directly interacts with various cellular and viral proteins
- p53 is the most commonly mutated gene in human cancer, with the majority of the mutations being amino acid substitutions
- The normal function of p53 is to effect cell cycle arrest at the G1 and G2 checkpoints in response to DNA damage
- This checkpoint function is executed by accumulation of p53 followed by induction of the GADD45, WAF1, and MDM2 genes
- The current model of p53 function postulates that p53 senses DNA damage and arrests the cell cycle in either the G1 or G2 phases to allow DNA repair to take place
- If repair is not successful, p53 initiates programmed cell death.
Compare Similar Items
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Antigen: p53 (Pantropic)
Classification: Monoclonal
Conjugate: Unconjugated
Host Species: Mouse
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Feline, Human
Form: Purified
Applications: Immunoblot, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation
Clone: DO-1
Formulation: In 0.05M sodium phosphate buffer, 0.2% gelatin.
Immunogen: wild type, recombinant, human p53
Regulatory Status: RUO
Test Specificity: Recognizes the ∽53kDa wild-type and mutant p53 protein in A431 cells and breast carcinoma tissue.
Content And Storage: 2°C to 8°C
Isotype: IgG2a
Antigen:
p53 (Pantropic)
Classification:
Monoclonal
Conjugate:
Unconjugated
Host Species:
Mouse
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Feline, Human
Form:
Purified
Applications:
Immunoblot, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation
Clone:
DO-1
Formulation:
In 0.05M sodium phosphate buffer, 0.2% gelatin.
Immunogen:
wild type, recombinant, human p53
Regulatory Status:
RUO
Test Specificity:
Recognizes the ∽53kDa wild-type and mutant p53 protein in A431 cells and breast carcinoma tissue.
Content And Storage:
2°C to 8°C
Isotype:
IgG2a
Antigen: MDM2
Classification: Monoclonal
Conjugate: Unconjugated
Host Species: Mouse
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Form: Purified
Applications: Immunoblot, Immunofluorescence, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation
Clone: IF2
Formulation: In 50mM sodium phosphate buffer, 0.2% gelatin.
Immunogen: human MDM2
Regulatory Status: RUO
Test Specificity: Recognizes the ∽90kDa (apparent MW) MDM2 protein. Also recognizes isoforms of ∽57kDa and ∽74/76kDa by immunoblotting.
Content And Storage: 2°C to 8°C
Isotype: IgG2b
Antigen:
MDM2
Classification:
Monoclonal
Conjugate:
Unconjugated
Host Species:
Mouse
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Form:
Purified
Applications:
Immunoblot, Immunofluorescence, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation
Clone:
IF2
Formulation:
In 50mM sodium phosphate buffer, 0.2% gelatin.
Immunogen:
human MDM2
Regulatory Status:
RUO
Test Specificity:
Recognizes the ∽90kDa (apparent MW) MDM2 protein. Also recognizes isoforms of ∽57kDa and ∽74/76kDa by immunoblotting.
Content And Storage:
2°C to 8°C
Isotype:
IgG2b
Antigen: c-ErbB2/c-Neu
Classification: Monoclonal
Conjugate: Unconjugated
Host Species: Mouse
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Form: Purified
Applications: Immunoblot
Clone: OD-3
Formulation: In 50mM sodium phosphate buffer, 0.2% gelatin.
Immunogen: cells overexpressing human c-Neu
Regulatory Status: RUO
Test Specificity: Recognizes the ∽97-115kDa truncated form of c-ErbB2/c-Neu in human serum as well as the ∽185kDa full-length protein. Does not cross-react with the EGF receptor.
Content And Storage: 2°C to 8°C
Isotype: IgM
Antigen:
c-ErbB2/c-Neu
Classification:
Monoclonal
Conjugate:
Unconjugated
Host Species:
Mouse
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Form:
Purified
Applications:
Immunoblot
Clone:
OD-3
Formulation:
In 50mM sodium phosphate buffer, 0.2% gelatin.
Immunogen:
cells overexpressing human c-Neu
Regulatory Status:
RUO
Test Specificity:
Recognizes the ∽97-115kDa truncated form of c-ErbB2/c-Neu in human serum as well as the ∽185kDa full-length protein. Does not cross-react with the EGF receptor.
Content And Storage:
2°C to 8°C
Isotype:
IgM
Antigen: APC
Classification: Monoclonal
Conjugate: Unconjugated
Host Species: Mouse
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Form: Purified
Applications: Immunocytochemistry, Immunofluorescence
Clone: CC-1
Formulation: In 50mM sodium phosphate buffer, 0.2% gelatin.
Immunogen: a recombinant protein consisting of amino acids 1-226 of APC
Regulatory Status: RUO
Test Specificity: Recognizes APC in oligodendrocytes and astrocytes. Antibody Target Gene Symbol: APC Target Synonym: AI047805, Apc7, AU020952, AW124434, BTPS2, DP2, DP2.5, DP3, Familial adenomatous polyposis, FAP, GS, Min, RATAPC Entrez Gene Name: adenomatous polyposis coli
Content And Storage: 2°C to 8°C
Isotype: IgG2b
Antigen:
APC
Classification:
Monoclonal
Conjugate:
Unconjugated
Host Species:
Mouse
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Form:
Purified
Applications:
Immunocytochemistry, Immunofluorescence
Clone:
CC-1
Formulation:
In 50mM sodium phosphate buffer, 0.2% gelatin.
Immunogen:
a recombinant protein consisting of amino acids 1-226 of APC
Regulatory Status:
RUO
Test Specificity:
Recognizes APC in oligodendrocytes and astrocytes. Antibody Target Gene Symbol: APC Target Synonym: AI047805, Apc7, AU020952, AW124434, BTPS2, DP2, DP2.5, DP3, Familial adenomatous polyposis, FAP, GS, Min, RATAPC Entrez Gene Name: adenomatous polyposis coli
Content And Storage:
2°C to 8°C
Isotype:
IgG2b