OP67100UG

MilliporeSigma™ anti-c-ErbB2/c-Neu Clone: OD-3,

Manufacturer: MilliporeSigma™

Select a Size

Pack Size SKU Availability Price
Each of 1 OP67100UG-Each-of-1 In Stock ₹ 46,364.96

OP67100UG - Each of 1

₹ 46,364.96

In Stock

Quantity

1

Base Price: ₹ 46,364.96

GST (18%): ₹ 8,345.693

Total Price: ₹ 54,710.653

Antigen

c-ErbB2/c-Neu

Classification

Monoclonal

Conjugate

Unconjugated

Host Species

Mouse

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Form

Purified

Applications

Immunoblot

Clone

OD-3

Formulation

In 50mM sodium phosphate buffer, 0.2% gelatin.

Immunogen

cells overexpressing human c-Neu

Regulatory Status

RUO

Test Specificity

Recognizes the ∽97-115kDa truncated form of c-ErbB2/c-Neu in human serum as well as the ∽185kDa full-length protein. Does not cross-react with the EGF receptor.

Content And Storage

2°C to 8°C

Isotype

IgM

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Description

  • Specifically detects c-ErbB2/c-Neu Clone: OD-3 in Human samples, and it is validated for Immuno Blotting Amplification of the human proto-oncogene c- neu occurs in approximately 30% of breast carcinomas and the amplification maybe a useful predictor of disease prognosis
  • Gene amplification and the resulting overexpression of proto-oncogene encoded proteins is thought to transform cells by chronically stimulating signal transduction pathways and in model systems overexpression of human c- neu induces cellular transformation
  • In the rat model system, a point mutation has been located within the transmembrane domain of the c- neu oncogene
  • neu (from neuroglioblastomas) is also referred to as erb B-2 (from erythroblastosis virus) and HER2 (for Human Epidermal Growth Factor Receptor) and was the second of four members of the EGF receptor family to be described.

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Img

MilliporeSigma™

OP67100UG

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Antigen:
c-ErbB2/c-Neu

Classification:
Monoclonal

Conjugate:
Unconjugated

Host Species:
Mouse

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Form:
Purified

Applications:
Immunoblot

Clone:
OD-3

Formulation:
In 50mM sodium phosphate buffer, 0.2% gelatin.

Immunogen:
cells overexpressing human c-Neu

Regulatory Status:
RUO

Test Specificity:
Recognizes the ∽97-115kDa truncated form of c-ErbB2/c-Neu in human serum as well as the ∽185kDa full-length protein. Does not cross-react with the EGF receptor.

Content And Storage:
2°C to 8°C

Isotype:
IgM

Img

MilliporeSigma™

OP80100UG

--


Antigen:
APC

Classification:
Monoclonal

Conjugate:
Unconjugated

Host Species:
Mouse

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Form:
Purified

Applications:
Immunocytochemistry, Immunofluorescence

Clone:
CC-1

Formulation:
In 50mM sodium phosphate buffer, 0.2% gelatin.

Immunogen:
a recombinant protein consisting of amino acids 1-226 of APC

Regulatory Status:
RUO

Test Specificity:
Recognizes APC in oligodendrocytes and astrocytes. Antibody Target Gene Symbol: APC Target Synonym: AI047805, Apc7, AU020952, AW124434, BTPS2, DP2, DP2.5, DP3, Familial adenomatous polyposis, FAP, GS, Min, RATAPC Entrez Gene Name: adenomatous polyposis coli

Content And Storage:
2°C to 8°C

Isotype:
IgG2b

Img

MilliporeSigma™

OP92100UG

--


Antigen:
BRCA1

Classification:
Monoclonal

Conjugate:
Unconjugated

Host Species:
Mouse

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Form:
Purified

Applications:
Immunoblot, Immunofluorescence, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation

Clone:
MS110

Formulation:
In 50mM sodium phosphate buffer, 0.2% gelatin, pH 7.5.

Immunogen:
recombinant human BRCA1

Regulatory Status:
RUO

Test Specificity:
Recognizes the ∽220kDa BRCA1 protein in MCF-7 cells. Does not cross-react with blood group antigens or growth factor receptors such as EGFR. Sold under license of U.S. Patent 5,753,441 and 6,162,897.

Content And Storage:
2°C to 8°C

Isotype:
IgG1

Img

MilliporeSigma™

OP93100UG

--


Antigen:
BRCA1

Classification:
Monoclonal

Conjugate:
Unconjugated

Host Species:
Mouse

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Form:
Purified

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation

Clone:
MS13

Formulation:
In 0.05M sodium phosphate buffer, 0.2% gelatin.

Immunogen:
recombinant, human BRCA1

Regulatory Status:
RUO

Test Specificity:
Recognizes the ∽220kDa BRCA1 protein in MCF-7 cells. Does not react with blood group antigens or growth factor receptors such as EGFR. Sold under license of U.S. Patent 5,753,441 and 6,162,897.

Content And Storage:
2°C to 8°C

Isotype:
IgG1