OP16L100UG
MilliporeSigma™ anti-c-ErbB2/c-Neu Clone: 7.16.4,
Manufacturer: MilliporeSigma™
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | OP16L100UG-Each-of-1 | In Stock | ₹ 46,364.96 |
OP16L100UG - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,364.96
GST (18%): ₹ 8,345.693
Total Price: ₹ 54,710.653
Antigen
c-ErbB2/c-Neu
Classification
Monoclonal
Conjugate
Unconjugated
Host Species
Mouse
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human, Rat
Form
Purified
Applications
Immunoblot, Immunocytochemistry, Immunohistochemistry (Frozen), Immunoprecipitation
Clone
7.16.4
Formulation
In 50mM sodium phosphate buffer, 0.2% gelatin, pH 7.5.
Immunogen
B104-1-1 cells overexpressing rat c-ErbB2/c-Neu
Regulatory Status
RUO
Test Specificity
Recognizes the ∽185kDa c-ErbB2/c-Neu protein in overexpressing B104-1-1 cells.
Content And Storage
2°C to 8°C
Isotype
IgG2a
Related Products
Description
- Specifically detects c-ErbB2/c-Neu Clone: 7.16.4 in Human, Rat samples, and it is validated for Immunocytochemistry, Immunohistochemistry (Frozen), Immunoprecipitation, Immuno Blotting Amplification of the human proto-oncogene c- neu occurs in approximately 30% of breast carcinomas and the amplification maybe a useful predictor of disease prognosis
- Gene amplification and the resulting overexpression of proto-oncogene encoded proteins is thought to transform cells by chronically stimulating signal transduction pathways and in model systems overexpression of human c- neu induces cellular transformation
- In the rat model system, a point mutation has been located within the transmembrane domain of the c- neu oncogene
- neu (from neu roglioblastomas) is also referred to as erbB-2 (from er ythro b lastosis virus) and HER2 (for H uman E pidermal Growth Factor R eceptor) and was the second of four members of the EGF receptor family to be described.
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Antigen: c-ErbB2/c-Neu
Classification: Monoclonal
Conjugate: Unconjugated
Host Species: Mouse
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Rat
Form: Purified
Applications: Immunoblot, Immunocytochemistry, Immunohistochemistry (Frozen), Immunoprecipitation
Clone: 7.16.4
Formulation: In 50mM sodium phosphate buffer, 0.2% gelatin, pH 7.5.
Immunogen: B104-1-1 cells overexpressing rat c-ErbB2/c-Neu
Regulatory Status: RUO
Test Specificity: Recognizes the ∽185kDa c-ErbB2/c-Neu protein in overexpressing B104-1-1 cells.
Content And Storage: 2°C to 8°C
Isotype: IgG2a
Antigen:
c-ErbB2/c-Neu
Classification:
Monoclonal
Conjugate:
Unconjugated
Host Species:
Mouse
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Rat
Form:
Purified
Applications:
Immunoblot, Immunocytochemistry, Immunohistochemistry (Frozen), Immunoprecipitation
Clone:
7.16.4
Formulation:
In 50mM sodium phosphate buffer, 0.2% gelatin, pH 7.5.
Immunogen:
B104-1-1 cells overexpressing rat c-ErbB2/c-Neu
Regulatory Status:
RUO
Test Specificity:
Recognizes the ∽185kDa c-ErbB2/c-Neu protein in overexpressing B104-1-1 cells.
Content And Storage:
2°C to 8°C
Isotype:
IgG2a
Antigen: c-Fos
Classification: Monoclonal
Conjugate: Unconjugated
Host Species: Mouse
Quantity: 200 μg
Primary or Secondary: Primary
Target Species: Human
Form: Liquid
Applications: Western Blot
Clone: 2G9C3
Formulation: In 50mM sodium phosphate buffer, 0.2% gelatin, pH 7.5, ≤0.1% Sodium Azide.
Immunogen: a synthetic peptide (KVEQLSPEEEEKRRIRRERNKMAAA) corresponding to amino acids 128-152 of human c-Fos
Regulatory Status: RUO
Test Specificity: __
Content And Storage: 2°-8°C
Isotype: IgG
Antigen:
c-Fos
Classification:
Monoclonal
Conjugate:
Unconjugated
Host Species:
Mouse
Quantity:
200 μg
Primary or Secondary:
Primary
Target Species:
Human
Form:
Liquid
Applications:
Western Blot
Clone:
2G9C3
Formulation:
In 50mM sodium phosphate buffer, 0.2% gelatin, pH 7.5, ≤0.1% Sodium Azide.
Immunogen:
a synthetic peptide (KVEQLSPEEEEKRRIRRERNKMAAA) corresponding to amino acids 128-152 of human c-Fos
Regulatory Status:
RUO
Test Specificity:
__
Content And Storage:
2°-8°C
Isotype:
IgG
Antigen: c-Fos
Classification: Monoclonal
Conjugate: Unconjugated
Host Species: Mouse
Quantity: 200 μg
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Form: Purified
Applications: Immunocytochemistry
Clone: 2G9C3
Formulation: Lyophilized from a volatile buffer, 200μg BSA.
Immunogen: a synthetic peptide (KVEQLSPEEEEKRRIRRERNKMAAA) corresponding to amino acids 128-152 of human c-Fos
Regulatory Status: RUO
Test Specificity: Recognizes both the ∽55kDa c-Fos and ∽62kDa v-Fos proteins in HeLa cells. Does not cross-react with the ∽39kDa Jun protein.
Content And Storage: 2°C to 8°C
Isotype: IgG2a
Antigen:
c-Fos
Classification:
Monoclonal
Conjugate:
Unconjugated
Host Species:
Mouse
Quantity:
200 μg
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Form:
Purified
Applications:
Immunocytochemistry
Clone:
2G9C3
Formulation:
Lyophilized from a volatile buffer, 200μg BSA.
Immunogen:
a synthetic peptide (KVEQLSPEEEEKRRIRRERNKMAAA) corresponding to amino acids 128-152 of human c-Fos
Regulatory Status:
RUO
Test Specificity:
Recognizes both the ∽55kDa c-Fos and ∽62kDa v-Fos proteins in HeLa cells. Does not cross-react with the ∽39kDa Jun protein.
Content And Storage:
2°C to 8°C
Isotype:
IgG2a
Antigen: Noxa
Classification: Monoclonal
Conjugate: Unconjugated
Host Species: Mouse
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Form: Purified
Applications: Immunoblot
Clone: 114C307
Formulation: In PBS, 0.05% BSA.
Immunogen: a recombinant protein consisting of human Noxa fused to GST
Regulatory Status: RUO
Test Specificity: Recognizes the ∽11kDa Noxa protein in RL-7 cells.
Content And Storage: −20°C
Isotype: IgG1
Antigen:
Noxa
Classification:
Monoclonal
Conjugate:
Unconjugated
Host Species:
Mouse
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Form:
Purified
Applications:
Immunoblot
Clone:
114C307
Formulation:
In PBS, 0.05% BSA.
Immunogen:
a recombinant protein consisting of human Noxa fused to GST
Regulatory Status:
RUO
Test Specificity:
Recognizes the ∽11kDa Noxa protein in RL-7 cells.
Content And Storage:
−20°C
Isotype:
IgG1