OP180100UG

MilliporeSigma™ anti-Noxa Clone: 114C307,

Manufacturer: MilliporeSigma™

Select a Size

Pack Size SKU Availability Price
Each of 1 OP180100UG-Each-of-1 In Stock ₹ 55,702.98

OP180100UG - Each of 1

₹ 55,702.98

In Stock

Quantity

1

Base Price: ₹ 55,702.98

GST (18%): ₹ 10,026.536

Total Price: ₹ 65,729.516

Antigen

Noxa

Classification

Monoclonal

Conjugate

Unconjugated

Host Species

Mouse

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Form

Purified

Applications

Immunoblot

Clone

114C307

Formulation

In PBS, 0.05% BSA.

Immunogen

a recombinant protein consisting of human Noxa fused to GST

Regulatory Status

RUO

Test Specificity

Recognizes the ∽11kDa Noxa protein in RL-7 cells.

Content And Storage

−20°C

Isotype

IgG1

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Description

  • Specifically detects Noxa Clone: 114C307 in Human samples, and it is validated for Immuno Blotting Noxa, a BH3 member of the Bcl-2 family, has recently been identified in human and mouse
  • Expression of the Noxa gene involves direct activation of its promoter by p53
  • Increased expression of Noxa occurs in normal thymocytes, but does not occur in p53-deficient thymocytes
  • Coimmunoprecipitation data suggests that Noxa may interact with other members of the Bcl-2 family, including Bcl-X L and Mcl-1
  • Data has also shown that blocking the endogenous Noxa induction results in the suppression of apoptosis
  • Treating cells with Noxa antisense oligonucleotides blocks radiation-induced apoptosis, and this suggests that Noxa may be a mediator of p53-dependent apoptosis.

Compare Similar Items

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Img

MilliporeSigma™

OP180100UG

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Antigen:
Noxa

Classification:
Monoclonal

Conjugate:
Unconjugated

Host Species:
Mouse

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Form:
Purified

Applications:
Immunoblot

Clone:
114C307

Formulation:
In PBS, 0.05% BSA.

Immunogen:
a recombinant protein consisting of human Noxa fused to GST

Regulatory Status:
RUO

Test Specificity:
Recognizes the ∽11kDa Noxa protein in RL-7 cells.

Content And Storage:
−20°C

Isotype:
IgG1

Img

MilliporeSigma™

OP187100UG

--


Antigen:
EpCAM-1

Classification:
Monoclonal

Conjugate:
Unconjugated

Host Species:
Mouse

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Form:
Purified

Applications:
Flow Cytometry, Immunoblot, Immunoblot, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation

Clone:
VU-1D9

Formulation:
In PBS.

Immunogen:
NCI-H69 human small cell lung carcinoma cells

Regulatory Status:
RUO

Test Specificity:
Recognizes the ∽40kDa EpCAM-1 protein in squamous cell carcinoma.

Content And Storage:
−20°C

Isotype:
IgG1

Img

MilliporeSigma™

OP188100UG

--


Antigen:
FAP

Classification:
Monoclonal

Conjugate:
Unconjugated

Host Species:
Mouse

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Form:
Purified

Applications:
Flow Cytometry, Immunohistochemistry (Frozen), Immunoprecipitation

Clone:
F11-24

Formulation:
In PBS.

Immunogen:
HEK293 cells transfected with an expression vector encoding full-length human FAP

Regulatory Status:
RUO

Test Specificity:
Recognizes fibroblast activation protein (FAP).

Content And Storage:
−20°C

Isotype:
IgG1

Img

MilliporeSigma™

OP20100UG

--


Antigen:
c-Abl

Classification:
Monoclonal

Conjugate:
Unconjugated

Host Species:
Mouse

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Form:
Purified

Applications:
Immunofluorescence, Immunoprecipitation

Clone:
24-21

Formulation:
In 0.05M sodium phosphate buffer, 0.2% gelatin, pH 7.5.

Immunogen:
a recombinant protein consisting of the carboxyl region of v-abl protein fused to TrpE

Regulatory Status:
RUO

Test Specificity:
Recognizes the ∽145kDa human c-Abl, the ∽150kDa mouse c-Abl, v-Abl, and the Bcr/Abl translocation products in ALL (∽190kDa) and CML (∽210kDa). Does not inhibit protein tyrosine kinase activity. Antibody Target Gene Symbol: ABL1 Target Synonym: ABL, AI325092, bcr/abl, C-ABL, C-ABL 1B, CABL1, E430008G22Rik, JTK7, MGC117749, p145Abl, p150, v-abl Entrez Gene Name: c-abl oncogene 1, receptor tyrosine kinase

Content And Storage:
2°C to 8°C

Isotype:
IgG1