OP20100UG
MilliporeSigma™ anti-c-Abl Clone: 24-21,
Manufacturer: MilliporeSigma™
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | OP20100UG-Each-of-1 | In Stock | ₹ 45,381.02 |
OP20100UG - Each of 1
In Stock
Quantity
1
Base Price: ₹ 45,381.02
GST (18%): ₹ 8,168.584
Total Price: ₹ 53,549.604
Antigen
c-Abl
Classification
Monoclonal
Conjugate
Unconjugated
Host Species
Mouse
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human, Mouse
Form
Purified
Applications
Immunofluorescence, Immunoprecipitation
Clone
24-21
Formulation
In 0.05M sodium phosphate buffer, 0.2% gelatin, pH 7.5.
Immunogen
a recombinant protein consisting of the carboxyl region of v-abl protein fused to TrpE
Regulatory Status
RUO
Test Specificity
Recognizes the ∽145kDa human c-Abl, the ∽150kDa mouse c-Abl, v-Abl, and the Bcr/Abl translocation products in ALL (∽190kDa) and CML (∽210kDa). Does not inhibit protein tyrosine kinase activity. Antibody Target Gene Symbol: ABL1 Target Synonym: ABL, AI325092, bcr/abl, C-ABL, C-ABL 1B, CABL1, E430008G22Rik, JTK7, MGC117749, p145Abl, p150, v-abl Entrez Gene Name: c-abl oncogene 1, receptor tyrosine kinase
Content And Storage
2°C to 8°C
Isotype
IgG1
Related Products
Description
- Specifically detects c-Abl Clone: 24-21 in Human, Mouse samples, and it is validated for Immunofluorescence, Immunoprecipitation The abl oncogene was initially identified as the viral transforming gene (v abl ) of Abelson murine leukemia virus (A-MuLV), from a chemically thymectomized mouse inoculated with Moloney murine leukemia virus (M MuLV)
- The v- abl genome consists of M-MuLV gag sequences fused to mouse c- abl , resulting in the production of phosphoproteins, p160 and p120 gag/c- abl with protein-tyrosine kinase activity, as the major translational products
- The abl oncogene is implicated in several human leukemias including 90-95% of chronic myelocytic (CML), 20-25% of adult acute lymphoblastic (ALL), and 2-5% of pediatric ALL
- In these leukemias the c- abl proto-oncogene undergoes a chromosomal (9;22) translocation producing the Philadelphia (Ph1) chromosome resulting in the fusion of c- abl sequences to the bcr gene of chromosome 22
- The molecular consequences of this translocation is the generation of a chimeric bcr /c- abl mRNA encoding activated abl protein-tyrosine kinase.
Compare Similar Items
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Antigen: c-Abl
Classification: Monoclonal
Conjugate: Unconjugated
Host Species: Mouse
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Mouse
Form: Purified
Applications: Immunofluorescence, Immunoprecipitation
Clone: 24-21
Formulation: In 0.05M sodium phosphate buffer, 0.2% gelatin, pH 7.5.
Immunogen: a recombinant protein consisting of the carboxyl region of v-abl protein fused to TrpE
Regulatory Status: RUO
Test Specificity: Recognizes the ∽145kDa human c-Abl, the ∽150kDa mouse c-Abl, v-Abl, and the Bcr/Abl translocation products in ALL (∽190kDa) and CML (∽210kDa). Does not inhibit protein tyrosine kinase activity. Antibody Target Gene Symbol: ABL1 Target Synonym: ABL, AI325092, bcr/abl, C-ABL, C-ABL 1B, CABL1, E430008G22Rik, JTK7, MGC117749, p145Abl, p150, v-abl Entrez Gene Name: c-abl oncogene 1, receptor tyrosine kinase
Content And Storage: 2°C to 8°C
Isotype: IgG1
Antigen:
c-Abl
Classification:
Monoclonal
Conjugate:
Unconjugated
Host Species:
Mouse
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Form:
Purified
Applications:
Immunofluorescence, Immunoprecipitation
Clone:
24-21
Formulation:
In 0.05M sodium phosphate buffer, 0.2% gelatin, pH 7.5.
Immunogen:
a recombinant protein consisting of the carboxyl region of v-abl protein fused to TrpE
Regulatory Status:
RUO
Test Specificity:
Recognizes the ∽145kDa human c-Abl, the ∽150kDa mouse c-Abl, v-Abl, and the Bcr/Abl translocation products in ALL (∽190kDa) and CML (∽210kDa). Does not inhibit protein tyrosine kinase activity. Antibody Target Gene Symbol: ABL1 Target Synonym: ABL, AI325092, bcr/abl, C-ABL, C-ABL 1B, CABL1, E430008G22Rik, JTK7, MGC117749, p145Abl, p150, v-abl Entrez Gene Name: c-abl oncogene 1, receptor tyrosine kinase
Content And Storage:
2°C to 8°C
Isotype:
IgG1
Antigen: c-H-Ras
Classification: Monoclonal
Conjugate: Unconjugated
Host Species: Mouse
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Form: Purified
Applications: Immunoblot, Immunofluorescence, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation
Clone: F235-1.7.1
Formulation: In 50mM sodium phosphate buffer, 0.2% gelatin, pH 7.4.
Immunogen: recombinant p21 Ras
Regulatory Status: RUO
Test Specificity: Recognizes the ∽21kDa c-H-Ras protein in normal skin tissue and Rat1 cells. Does not react with c-K-Ras or c-N-Ras p21. A doublet may be seen due to farnesylation.
Content And Storage: 2°C to 8°C
Isotype: IgG1
Antigen:
c-H-Ras
Classification:
Monoclonal
Conjugate:
Unconjugated
Host Species:
Mouse
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Form:
Purified
Applications:
Immunoblot, Immunofluorescence, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation
Clone:
F235-1.7.1
Formulation:
In 50mM sodium phosphate buffer, 0.2% gelatin, pH 7.4.
Immunogen:
recombinant p21 Ras
Regulatory Status:
RUO
Test Specificity:
Recognizes the ∽21kDa c-H-Ras protein in normal skin tissue and Rat1 cells. Does not react with c-K-Ras or c-N-Ras p21. A doublet may be seen due to farnesylation.
Content And Storage:
2°C to 8°C
Isotype:
IgG1
Antigen: c-H-Ras
Classification: Monoclonal
Conjugate: Unconjugated
Host Species: Mouse
Quantity: 200 μg
Primary or Secondary: Primary
Target Species: Human
Form: Liquid
Applications: Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin)
Clone: F235-1.7.1
Formulation: In 50mM sodium phosphate buffer, 0.2% gelatin, pH 7.4, ≤0.1% Sodium Azide.
Immunogen: recombinant p21 Ras
Regulatory Status: RUO
Test Specificity: __
Content And Storage: 2°-8°C
Isotype: IgG1
Antigen:
c-H-Ras
Classification:
Monoclonal
Conjugate:
Unconjugated
Host Species:
Mouse
Quantity:
200 μg
Primary or Secondary:
Primary
Target Species:
Human
Form:
Liquid
Applications:
Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin)
Clone:
F235-1.7.1
Formulation:
In 50mM sodium phosphate buffer, 0.2% gelatin, pH 7.4, ≤0.1% Sodium Azide.
Immunogen:
recombinant p21 Ras
Regulatory Status:
RUO
Test Specificity:
__
Content And Storage:
2°-8°C
Isotype:
IgG1
Antigen: c-K-Ras
Classification: Monoclonal
Conjugate: Unconjugated
Host Species: Mouse
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Form: Purified
Applications: Immunoblot, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation
Clone: 234-4.2
Formulation: In 50mM sodium phosphate buffer, 0.2% gelatin, pH 7.5.
Immunogen: recombinant, rat K-Ras
Regulatory Status: RUO
Test Specificity: Recognizes c-K-Ras and v-K-Ras in SW480 and Y1 cells and normal skin tissue. Cross-reacts with c-H-Ras and c-N-Ras.
Content And Storage: 2°C to 8°C
Isotype: IgG2a
Antigen:
c-K-Ras
Classification:
Monoclonal
Conjugate:
Unconjugated
Host Species:
Mouse
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Form:
Purified
Applications:
Immunoblot, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation
Clone:
234-4.2
Formulation:
In 50mM sodium phosphate buffer, 0.2% gelatin, pH 7.5.
Immunogen:
recombinant, rat K-Ras
Regulatory Status:
RUO
Test Specificity:
Recognizes c-K-Ras and v-K-Ras in SW480 and Y1 cells and normal skin tissue. Cross-reacts with c-H-Ras and c-N-Ras.
Content And Storage:
2°C to 8°C
Isotype:
IgG2a