NP23304A32

MALT1 Antibody (MT1/410), Alexa Fluor™ 532, Novus Biologicals™

Manufacturer: Novus Biologicals

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Pack Size SKU Availability Price
Each of 1 NP23304A32-Each-of-1 In Stock ₹ 55,271.76

NP23304A32 - Each of 1

₹ 55,271.76

In Stock

Quantity

1

Base Price: ₹ 55,271.76

GST (18%): ₹ 9,948.917

Total Price: ₹ 65,220.677

Antigen

MALT1

Classification

Monoclonal

Conjugate

Alexa Fluor 532

Formulation

50 mM sodium borate with 0.05% sodium azide

Gene Symbols

MALT1

Immunogen

Human MALT1 recombinant fragment (aa701-808) (Uniprot: Q9UDY8)

Quantity

0.1 mL

Primary or Secondary

Primary

Test Specificity

Mucosa associated lymphoid tissue lymphoma translocation gene 1 (MALT1) is found in extranodal low-grade B cell lymphomas. MALT1 encodes two Ig-like C2-type domains and fuses with an API2 gene, which is highly expressed in adult lymphoid tissue. The translocation of this MALT1 gene, which maps to human chromosome 18q21, and the apoptosis-inhibiting API2 gene results in an increased development of MALT lymphomas and apoptosis inhibition. Sites at which this API2-MALT1 (11;18)(q21;q21) translocation commonly occurs are within human lung and kidney tissue. MALT lymphoma expresses nuclear Bcl10, which mediates the oligomerization and activation of a MALT1 caspase-like domain. MALT1 mRNA is found in pre-B cells, mature B cells and plasma cells.

Content And Storage

Store at 4°C in the dark.

Applications

ELISA

Clone

MT1/410

Dilution

ELISA

Gene Alias

caspase-like protein, DKFZp434L132, EC 3.4.22.-, MALT associated translocation, MALT lymphoma-associated translocation, MLT1, MLTMALT-lymphoma associated translocation, mucosa associated lymphoid tissue lymphoma translocation gene 1, mucosa-associated lymphoid tissue lymphoma translocation protein 1, paracaspase

Host Species

Mouse

Purification Method

Protein A or G purified

Research Discipline

Apoptosis, Cancer, Tumor Suppressors

Gene ID (Entrez)

10892.0

Target Species

Human

Isotype

IgG1 κ

Description

  • MALT1 Monoclonal specifically detects MALT1 in Human samples
  • It is validated for Western Blot, Immunohistochemistry, Immunohistochemistry-Paraffin.

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Novus Biologicals

NP23304A32

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Antigen:
MALT1

Classification:
Monoclonal

Conjugate:
Alexa Fluor 532

Formulation:
50 mM sodium borate with 0.05% sodium azide

Gene Symbols:
MALT1

Immunogen:
Human MALT1 recombinant fragment (aa701-808) (Uniprot: Q9UDY8)

Quantity:
0.1 mL

Primary or Secondary:
Primary

Test Specificity:
Mucosa associated lymphoid tissue lymphoma translocation gene 1 (MALT1) is found in extranodal low-grade B cell lymphomas. MALT1 encodes two Ig-like C2-type domains and fuses with an API2 gene, which is highly expressed in adult lymphoid tissue. The translocation of this MALT1 gene, which maps to human chromosome 18q21, and the apoptosis-inhibiting API2 gene results in an increased development of MALT lymphomas and apoptosis inhibition. Sites at which this API2-MALT1 (11;18)(q21;q21) translocation commonly occurs are within human lung and kidney tissue. MALT lymphoma expresses nuclear Bcl10, which mediates the oligomerization and activation of a MALT1 caspase-like domain. MALT1 mRNA is found in pre-B cells, mature B cells and plasma cells.

Content And Storage:
Store at 4°C in the dark.

Applications:
ELISA

Clone:
MT1/410

Dilution:
ELISA

Gene Alias:
caspase-like protein, DKFZp434L132, EC 3.4.22.-, MALT associated translocation, MALT lymphoma-associated translocation, MLT1, MLTMALT-lymphoma associated translocation, mucosa associated lymphoid tissue lymphoma translocation gene 1, mucosa-associated lymphoid tissue lymphoma translocation protein 1, paracaspase

Host Species:
Mouse

Purification Method:
Protein A or G purified

Research Discipline:
Apoptosis, Cancer, Tumor Suppressors

Gene ID (Entrez):
10892.0

Target Species:
Human

Isotype:
IgG1 κ

Img

Novus Biologicals

NP233060A32

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Antigen:
Vimentin

Classification:
Monoclonal

Conjugate:
Alexa Fluor 532

Formulation:
50 mM sodium borate with 0.05% sodium azide

Gene Symbols:
VIM

Immunogen:
Recombinant full-length human vimentin protein (Uniprot: P08670)

Quantity:
0.1 mL

Primary or Secondary:
Primary

Test Specificity:
This monoclonal antibody reacts with a 58kDa protein identified as Vimentin. It shows no cross-reaction with other closely related intermediate filament proteins (IFP however, when used in panels with other antibodies, it is useful for the sub-classification of a given tumor. Expression of Vimentin, when used in conjunction with anti-keratin, is helpful when distinguishing melanomas from undifferentiated carcinomas and large cell lymphomas. All melanomas and Schwannomas react strongly with anti-Vimentin. It labels a variety of mesenchymal cells, including melanocytes, lymphocytes, endothelial cells, and fibroblasts. Non-reactivity of anti-Vimentin is often considered more useful than its positive reactivity, since there are a few tumors that do not contain Vimentin, e.g. hepatoma and seminoma. Anti-Vimentin is also useful as a tissue process control reagent.

Content And Storage:
Store at 4°C in the dark.

Applications:
Western Blot, ELISA, Immunoassay

Clone:
VM452

Dilution:
Western Blot, ELISA, Knockout Validated

Gene Alias:
FLJ36605, vimentin

Host Species:
Mouse

Purification Method:
Protein A or G purified

Research Discipline:
Biologically Active Proteins, Cancer, Cellular Markers, Cytoskeleton Markers, Growth and Development, Hypoxia, Neuronal Cell Markers, Neuronal Stem Cell Markers, Neuroscience, Phospho Specific, Signal Transduction, Stem Cell Markers, Stem Cells

Gene ID (Entrez):
7431.0

Target Species:
Human, Porcine, Bovine, Canine, Chicken, Feline, Goat, Mouse, Rat

Isotype:
IgG1 κ

Img

Novus Biologicals

NP233060A70

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Antigen:
Vimentin

Classification:
Monoclonal

Conjugate:
Alexa Fluor 750

Formulation:
50 mM sodium borate with 0.05% sodium azide

Gene Symbols:
VIM

Immunogen:
Recombinant full-length human vimentin protein (Uniprot: P08670)

Quantity:
0.1 mL

Primary or Secondary:
Primary

Test Specificity:
This monoclonal antibody reacts with a 58kDa protein identified as Vimentin. It shows no cross-reaction with other closely related intermediate filament proteins (IFP however, when used in panels with other antibodies, it is useful for the sub-classification of a given tumor. Expression of Vimentin, when used in conjunction with anti-keratin, is helpful when distinguishing melanomas from undifferentiated carcinomas and large cell lymphomas. All melanomas and Schwannomas react strongly with anti-Vimentin. It labels a variety of mesenchymal cells, including melanocytes, lymphocytes, endothelial cells, and fibroblasts. Non-reactivity of anti-Vimentin is often considered more useful than its positive reactivity, since there are a few tumors that do not contain Vimentin, e.g. hepatoma and seminoma. Anti-Vimentin is also useful as a tissue process control reagent.

Content And Storage:
Store at 4°C in the dark.

Applications:
Western Blot, ELISA, Immunoassay

Clone:
VM452

Dilution:
Western Blot, ELISA, Knockout Validated

Gene Alias:
FLJ36605, vimentin

Host Species:
Mouse

Purification Method:
Protein A or G purified

Research Discipline:
__

Gene ID (Entrez):
7431

Target Species:
Human, Porcine, Bovine, Canine, Chicken, Feline, Goat, Mouse, Rat

Isotype:
IgG1 κ

Img

Novus Biologicals

NP233062A30

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Antigen:
NF-H

Classification:
Monoclonal

Conjugate:
Alexa Fluor 350

Formulation:
50 mM sodium borate with 0.05% sodium azide

Gene Symbols:
NEFH

Immunogen:
Triton-X 100 insoluble protein fraction of rat brain (Uniprot: P12036)

Quantity:
0.1 mL

Primary or Secondary:
Primary

Test Specificity:
This monoclonal antibody reacts with a 200kDa protein, identified as heavy sub-unit of neurofilaments (NF-H). Neurofilaments make up the main structural elements of axons and dendrites and are found in neurons, peripheral nerves, and sympathetic ganglion cells. Neurofilaments consist of three major subunits with molecular weights of 68kDa (NF-L), 160kDa (NF-M) and 200kDa (NF-H). Anti-neurofilament stains a number of neural, neuroendocrine, and endocrine tumors. Neuromas, ganglioneuromas, gangliogliomas, ganglioneuroblastomas, and neuroblastomas stain positively for anti-neurofilament. Neurofilaments are also present in paragangliomas as well as adrenal and extra-adrenal pheochromocytomas. Carcinoids, neuroendocrine carcinomas of the skin, and oat cell carcinomas of the lung also express neurofilament.

Content And Storage:
Store at 4°C in the dark.

Applications:
ELISA

Clone:
RT97

Dilution:
ELISA

Gene Alias:
200 kDa neurofilament protein, KIAA0845, Neurofilament Heavy (200kDa), neurofilament heavy polypeptide, Neurofilament triplet H protein, neurofilament, heavy polypeptide, neurofilament, heavy polypeptide 200kDa, NF200, NFH, NF-H

Host Species:
Mouse

Purification Method:
Protein A or G purified

Research Discipline:
Autophagy, Cellular Markers, Cytoskeleton Markers, Neurodegeneration, Neurofilaments, Neuronal Cell Markers, Neuroscience

Gene ID (Entrez):
4744.0

Target Species:
Human, Mouse, Rat, Porcine, Chicken

Isotype:
IgG1 κ