NP234662A94

CD68/SR-D1 Antibody (KP1 + C68/684), Alexa Fluor™ 594, Novus Biologicals™

Manufacturer: Novus Biologicals

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Pack Size SKU Availability Price
Each of 1 NP234662A94-Each-of-1 In Stock ₹ 55,271.76

NP234662A94 - Each of 1

₹ 55,271.76

In Stock

Quantity

1

Base Price: ₹ 55,271.76

GST (18%): ₹ 9,948.917

Total Price: ₹ 65,220.677

Antigen

CD68/SR-D1

Classification

Monoclonal

Conjugate

Alexa Fluor 594

Formulation

50 mM sodium borate with 0.05% sodium azide

Gene Symbols

CD68

Immunogen

This CD68/SR-D1 Antibody (KP1 + C68/684) was developed against subcellular fraction of human alveolar macrophages (KP1); Recombinant human CD68 protein (C68/684).

Quantity

0.1 mL

Primary or Secondary

Primary

Test Specificity

This antibody recognizes a glycoprotein of 110kDa, which is identified as CD68. It is important for identifying macrophages in tissue sections. It stains macrophages in a wide variety of human tissues, including Kupffer cells and macrophages in the red pulp of the spleen, in lamina propria of the gut, in lung alveoli, and in bone marrow. It reacts with myeloid precursors and peripheral blood granulocytes. It also reacts with plasmacytoid T cells, which are supposed to be of monocyte/macrophage origin. It shows strong granular cytoplasmic staining of chronic and acute myeloid leukemia and also reacts with rare cases of true histiocytic neoplasia. Lymphomas are negative or show few granules.

Content And Storage

Store at 4°C in the dark.

Applications

Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen)

Clone

KP1 + C68/684

Dilution

Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen, Flow (Intracellular)

Gene Alias

CD68 antigenmacrophage antigen CD68, CD68 molecule, DKFZp686M18236, GP110, macrosialin, SCARD1, scavenger receptor class D, member 1

Host Species

Mouse

Purification Method

Protein A or G purified

Research Discipline

Cell Biology, Cytokine Research, Immunology, Microglia Markers

Gene ID (Entrez)

968

Target Species

Human, Feline, Primate, Rat

Isotype

IgG1 κ

Description

  • CD68/SR-D1 Monoclonal specifically detects CD68/SR-D1 in Human, Mouse, Rat, Feline, Monkey samples
  • It is validated for Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Paraffin, Flow (Intracellular).

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Novus Biologicals

NP234662A94

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Antigen:
CD68/SR-D1

Classification:
Monoclonal

Conjugate:
Alexa Fluor 594

Formulation:
50 mM sodium borate with 0.05% sodium azide

Gene Symbols:
CD68

Immunogen:
This CD68/SR-D1 Antibody (KP1 + C68/684) was developed against subcellular fraction of human alveolar macrophages (KP1); Recombinant human CD68 protein (C68/684).

Quantity:
0.1 mL

Primary or Secondary:
Primary

Test Specificity:
This antibody recognizes a glycoprotein of 110kDa, which is identified as CD68. It is important for identifying macrophages in tissue sections. It stains macrophages in a wide variety of human tissues, including Kupffer cells and macrophages in the red pulp of the spleen, in lamina propria of the gut, in lung alveoli, and in bone marrow. It reacts with myeloid precursors and peripheral blood granulocytes. It also reacts with plasmacytoid T cells, which are supposed to be of monocyte/macrophage origin. It shows strong granular cytoplasmic staining of chronic and acute myeloid leukemia and also reacts with rare cases of true histiocytic neoplasia. Lymphomas are negative or show few granules.

Content And Storage:
Store at 4°C in the dark.

Applications:
Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen)

Clone:
KP1 + C68/684

Dilution:
Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen, Flow (Intracellular)

Gene Alias:
CD68 antigenmacrophage antigen CD68, CD68 molecule, DKFZp686M18236, GP110, macrosialin, SCARD1, scavenger receptor class D, member 1

Host Species:
Mouse

Purification Method:
Protein A or G purified

Research Discipline:
Cell Biology, Cytokine Research, Immunology, Microglia Markers

Gene ID (Entrez):
968

Target Species:
Human, Feline, Primate, Rat

Isotype:
IgG1 κ

Img

Novus Biologicals

NP234663A30

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Antigen:
Ku70/XRCC6

Classification:
Monoclonal

Conjugate:
Alexa Fluor 350

Formulation:
50 mM sodium borate with 0.05% sodium azide

Gene Symbols:
XRCC6

Immunogen:
Nuclear extract of human HL-60 cells

Quantity:
0.1 mL

Primary or Secondary:
Primary

Test Specificity:
Recognizes a dimer of two proteins of 70kDa and ∼80kDa, identified as two subunits of Ku. This monoclonal antibody recognizes a conformational epitope of p70/p80 dimer, which is destroyed during Western blotting. The p70/p80 dimer is important for function of a 460kDa DNA-dependent protein kinase. Ku protein plays a role in cell signaling, proliferation, DNA repair, replication, transcriptional activation, and apoptosis.

Content And Storage:
Store at 4°C in the dark.

Applications:
Flow Cytometry, Immunocytochemistry, Immunofluorescence

Clone:
KU729

Dilution:
Flow Cytometry, Immunocytochemistry/Immunofluorescence, Flow (Intracellular)

Gene Alias:
5′-deoxyribose-5-phosphate lyase Ku70, 5′-dRP lyase Ku70, 70 kDa subunit of Ku antigen, ATP-dependent DNA helicase 2 subunit 1, ATP-dependent DNA helicase II 70 kDa subunit, CTC box binding factor 75 kDa subunit, CTC box-binding factor 75 kDa subunit, CTC75, CTCBF, D22S731, EC 3.6.4.-, EC 4.2.99.-, G22P1Ku70, Ku autoantigen p70 subunit, Ku autoantigen, 70kDa, KU70, ML8,70 kDa subunit, Thyroid-lupus autoantigen, thyroid-lupus autoantigen p70, TLAAD22S671, X-ray repair complementing defective repair in Chinese hamster cells 6DNA repair protein XRCC6, X-ray repair cross-complementing protein 6

Host Species:
Mouse

Purification Method:
Protein A or G purified

Research Discipline:
__

Gene ID (Entrez):
2547

Target Species:
Human, Primate, Chicken, Mouse, Rat

Isotype:
IgG1 κ

Img

Novus Biologicals

NP234663A32

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Antigen:
Ku70/XRCC6

Classification:
Monoclonal

Conjugate:
Alexa Fluor 532

Formulation:
50 mM sodium borate with 0.05% sodium azide

Gene Symbols:
XRCC6

Immunogen:
Nuclear extract of human HL-60 cells

Quantity:
0.1 mL

Primary or Secondary:
Primary

Test Specificity:
Recognizes a dimer of two proteins of 70kDa and ∼80kDa, identified as two subunits of Ku. This monoclonal antibody recognizes a conformational epitope of p70/p80 dimer, which is destroyed during Western blotting. The p70/p80 dimer is important for function of a 460kDa DNA-dependent protein kinase. Ku protein plays a role in cell signaling, proliferation, DNA repair, replication, transcriptional activation, and apoptosis.

Content And Storage:
Store at 4°C in the dark.

Applications:
Flow Cytometry, Immunocytochemistry, Immunofluorescence

Clone:
KU729

Dilution:
Flow Cytometry, Immunocytochemistry/Immunofluorescence, Flow (Intracellular)

Gene Alias:
5′-deoxyribose-5-phosphate lyase Ku70, 5′-dRP lyase Ku70, 70 kDa subunit of Ku antigen, ATP-dependent DNA helicase 2 subunit 1, ATP-dependent DNA helicase II 70 kDa subunit, CTC box binding factor 75 kDa subunit, CTC box-binding factor 75 kDa subunit, CTC75, CTCBF, D22S731, EC 3.6.4.-, EC 4.2.99.-, G22P1Ku70, Ku autoantigen p70 subunit, Ku autoantigen, 70kDa, KU70, ML8,70 kDa subunit, Thyroid-lupus autoantigen, thyroid-lupus autoantigen p70, TLAAD22S671, X-ray repair complementing defective repair in Chinese hamster cells 6DNA repair protein XRCC6, X-ray repair cross-complementing protein 6

Host Species:
Mouse

Purification Method:
Protein A or G purified

Research Discipline:
Breast Cancer, Cancer, DNA Double Strand Break Repair, DNA Repair, Non homologous end joining

Gene ID (Entrez):
2547.0

Target Species:
Human, Primate, Chicken, Mouse, Rat

Isotype:
IgG1 κ

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Novus Biologicals

NP234664A30

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Antigen:
Lambda Light Chain

Classification:
Monoclonal

Conjugate:
Alexa Fluor 350

Formulation:
50 mM sodium borate with 0.05% sodium azide

Gene Symbols:
IGLC1

Immunogen:
Purified human lambda light chain

Quantity:
0.1 mL

Primary or Secondary:
Primary

Test Specificity:
This monoclonal antibody is specific to Lambda Light Chain of immunoglobulin and shows no cross-reaction with Lambda Light Chain or any of the five heavy chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. The ratio of Kappa to Lambda is 70:30. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the Lambda Light Chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkins lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant.

Content And Storage:
Store at 4°C in the dark.

Applications:
Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)

Clone:
LAM03

Dilution:
Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen

Gene Alias:
IGLC, immunoglobulin lambda constant group

Host Species:
Mouse

Purification Method:
Protein A or G purified

Research Discipline:
Adaptive Immunity, Immunology

Gene ID (Entrez):
3537.0

Target Species:
Human

Isotype:
IgG1 κ