Manufacturer: Novus Biologicals
Pack Size | SKU | Availability | Price |
---|---|---|---|
Each of 1 | NP2429A32-Each-of-1 | In Stock | ₹ 55,271.76 |
NP2429A32 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 55,271.76
GST (18%): ₹ 9,948.917
Total Price: ₹ 65,220.677
Desmoglein-2
Monoclonal
Alexa Fluor 532
50 mM sodium borate with 0.05% sodium azide
DSG2
Recombinant human Desmoglein-2 protein (Uniprot: Q14126)
Primary
Recognizes a protein of 165kDa, identified as Desmoglein-2 (DSG2). This monoclonal antibody recognizes the extracellular domain of human desmoglein-2. Desmoglein-2 is a member of the desmosomal cadherin family. Desmosomes are intercellular adhering junctions that represent cell surface attachment sites for intermediate filament. Desmocollins and desmogleins are the main desmosomal transmembrane proteins. Desmogleins consist of Dsg1, Dsg2, Dsg3, and Dsg4 isoforms. Within the desmosome, the extracellular domain of desmoglein is essential for calcium dependent heterophilic binding to the desmocollins, whereas the intracellular domain is essential for binding to the desmosomal plaque protein, plakoglobin. Human Desmoglein-2 is a type I transmembrane glycoprotein of 1117 amino acid (aa) residues with a 23 aa signal peptide and a 25 aa propeptide. It differs from other classic cadherins by having four instead of five cadherin repeat domains in its extracellular region, and a much larger cyto
Store at 4°C in the dark.
Western Blot, Flow Cytometry, Immunocytochemistry, Immunofluorescence
[8E5]
Western Blot, Flow Cytometry, Immunocytochemistry/Immunofluorescence
ARVC10, ARVD10, Cadherin family member 5, CDHF5MGC117034, CMD1BB, desmoglein 2, desmoglein-2, HDGC, MGC117036, MGC117037
Mouse
0.1 mL
1829
Human
IgG1 κ