NP247703A30
beta 2-Microglobulin Antibody (SPM617), Alexa Fluor™ 350, Novus Biologicals™
Manufacturer: Novus Biologicals
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | NP247703A30-Each-of-1 | In Stock | ₹ 55,271.76 |
NP247703A30 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 55,271.76
GST (18%): ₹ 9,948.917
Total Price: ₹ 65,220.677
Antigen
beta 2-Microglobulin
Classification
Monoclonal
Conjugate
Alexa Fluor 350
Formulation
50 mM sodium borate with 0.05% sodium azide
Gene Symbols
B2M
Immunogen
Full length recombinant human beta 2-Microglobulin protein (Uniprot: P61769)
Primary or Secondary
Primary
Test Specificity
Beta2 microglobulin is a 12KDa protein with a pI of 5.6. Serum beta2 microglobulin levels are a reflection of cell turnover. Levels rise with fever, inflammation, and infection. Increased serum levels are also seen in B-cell malignancies and in renal failure and may indicate a worse prognosis for patients with early-stage Hodgkin′s lymphoma. In urine, increased levels are seen in proximal renal tubular disease as well as renal transplant rejection. Beta2 microglobulin levels can rise either because its rate of synthesis has increased (e.g. in AIDS, malignant monoclonal plasma cell dyscrasia, solid tumours and autoimmune disease) or because of impaired renal filtration (e.g. due to renal insufficiency, graft rejection or nephrotoxicity induced by post-transplantation immunosuppressive therapy)
Content And Storage
Store at 4°C in the dark.
Applications
Flow Cytometry, Immunohistochemistry, Immunohistochemistry (Paraffin), Immunofluorescence
Clone
SPM617
Dilution
Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Paraffin, Flow (Cell Surface), Immunofluorescence
Gene Alias
beta chain of MHC class I molecules, beta-2-microglobin, beta-2-microglobulin
Host Species
Mouse
Quantity
0.1 mL
Gene ID (Entrez)
567
Target Species
Human, Primate
Isotype
IgG1 κ
Related Products
Description
- beta 2-Microglobulin Monoclonal specifically detects beta 2-Microglobulin in Human, Primate samples
- It is validated for Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Flow (Cell Surface), Immunofluorescence.
Compare Similar Items
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Antigen: beta 2-Microglobulin
Classification: Monoclonal
Conjugate: Alexa Fluor 350
Formulation: 50 mM sodium borate with 0.05% sodium azide
Gene Symbols: B2M
Immunogen: Full length recombinant human beta 2-Microglobulin protein (Uniprot: P61769)
Primary or Secondary: Primary
Test Specificity: Beta2 microglobulin is a 12KDa protein with a pI of 5.6. Serum beta2 microglobulin levels are a reflection of cell turnover. Levels rise with fever, inflammation, and infection. Increased serum levels are also seen in B-cell malignancies and in renal failure and may indicate a worse prognosis for patients with early-stage Hodgkin′s lymphoma. In urine, increased levels are seen in proximal renal tubular disease as well as renal transplant rejection. Beta2 microglobulin levels can rise either because its rate of synthesis has increased (e.g. in AIDS, malignant monoclonal plasma cell dyscrasia, solid tumours and autoimmune disease) or because of impaired renal filtration (e.g. due to renal insufficiency, graft rejection or nephrotoxicity induced by post-transplantation immunosuppressive therapy)
Content And Storage: Store at 4°C in the dark.
Applications: Flow Cytometry, Immunohistochemistry, Immunohistochemistry (Paraffin), Immunofluorescence
Clone: SPM617
Dilution: Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Paraffin, Flow (Cell Surface), Immunofluorescence
Gene Alias: beta chain of MHC class I molecules, beta-2-microglobin, beta-2-microglobulin
Host Species: Mouse
Quantity: 0.1 mL
Gene ID (Entrez): 567
Target Species: Human, Primate
Isotype: IgG1 κ
Antigen:
beta 2-Microglobulin
Classification:
Monoclonal
Conjugate:
Alexa Fluor 350
Formulation:
50 mM sodium borate with 0.05% sodium azide
Gene Symbols:
B2M
Immunogen:
Full length recombinant human beta 2-Microglobulin protein (Uniprot: P61769)
Primary or Secondary:
Primary
Test Specificity:
Beta2 microglobulin is a 12KDa protein with a pI of 5.6. Serum beta2 microglobulin levels are a reflection of cell turnover. Levels rise with fever, inflammation, and infection. Increased serum levels are also seen in B-cell malignancies and in renal failure and may indicate a worse prognosis for patients with early-stage Hodgkin′s lymphoma. In urine, increased levels are seen in proximal renal tubular disease as well as renal transplant rejection. Beta2 microglobulin levels can rise either because its rate of synthesis has increased (e.g. in AIDS, malignant monoclonal plasma cell dyscrasia, solid tumours and autoimmune disease) or because of impaired renal filtration (e.g. due to renal insufficiency, graft rejection or nephrotoxicity induced by post-transplantation immunosuppressive therapy)
Content And Storage:
Store at 4°C in the dark.
Applications:
Flow Cytometry, Immunohistochemistry, Immunohistochemistry (Paraffin), Immunofluorescence
Clone:
SPM617
Dilution:
Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Paraffin, Flow (Cell Surface), Immunofluorescence
Gene Alias:
beta chain of MHC class I molecules, beta-2-microglobin, beta-2-microglobulin
Host Species:
Mouse
Quantity:
0.1 mL
Gene ID (Entrez):
567
Target Species:
Human, Primate
Isotype:
IgG1 κ
Antigen: beta 2-Microglobulin
Classification: Monoclonal
Conjugate: Alexa Fluor 532
Formulation: 50 mM sodium borate with 0.05% sodium azide
Gene Symbols: B2M
Immunogen: Full length recombinant human beta 2-Microglobulin protein (Uniprot: P61769)
Primary or Secondary: Primary
Test Specificity: Beta2 microglobulin is a 12KDa protein with a pI of 5.6. Serum beta2 microglobulin levels are a reflection of cell turnover. Levels rise with fever, inflammation, and infection. Increased serum levels are also seen in B-cell malignancies and in renal failure and may indicate a worse prognosis for patients with early-stage Hodgkin′s lymphoma. In urine, increased levels are seen in proximal renal tubular disease as well as renal transplant rejection. Beta2 microglobulin levels can rise either because its rate of synthesis has increased (e.g. in AIDS, malignant monoclonal plasma cell dyscrasia, solid tumours and autoimmune disease) or because of impaired renal filtration (e.g. due to renal insufficiency, graft rejection or nephrotoxicity induced by post-transplantation immunosuppressive therapy)
Content And Storage: Store at 4°C in the dark.
Applications: Flow Cytometry, Immunohistochemistry, Immunohistochemistry (Paraffin), Immunofluorescence
Clone: SPM617
Dilution: Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Paraffin, Flow (Cell Surface), Immunofluorescence
Gene Alias: beta chain of MHC class I molecules, beta-2-microglobin, beta-2-microglobulin
Host Species: Mouse
Quantity: 0.1 mL
Gene ID (Entrez): 567.0
Target Species: Human, Primate
Isotype: IgG1 κ
Antigen:
beta 2-Microglobulin
Classification:
Monoclonal
Conjugate:
Alexa Fluor 532
Formulation:
50 mM sodium borate with 0.05% sodium azide
Gene Symbols:
B2M
Immunogen:
Full length recombinant human beta 2-Microglobulin protein (Uniprot: P61769)
Primary or Secondary:
Primary
Test Specificity:
Beta2 microglobulin is a 12KDa protein with a pI of 5.6. Serum beta2 microglobulin levels are a reflection of cell turnover. Levels rise with fever, inflammation, and infection. Increased serum levels are also seen in B-cell malignancies and in renal failure and may indicate a worse prognosis for patients with early-stage Hodgkin′s lymphoma. In urine, increased levels are seen in proximal renal tubular disease as well as renal transplant rejection. Beta2 microglobulin levels can rise either because its rate of synthesis has increased (e.g. in AIDS, malignant monoclonal plasma cell dyscrasia, solid tumours and autoimmune disease) or because of impaired renal filtration (e.g. due to renal insufficiency, graft rejection or nephrotoxicity induced by post-transplantation immunosuppressive therapy)
Content And Storage:
Store at 4°C in the dark.
Applications:
Flow Cytometry, Immunohistochemistry, Immunohistochemistry (Paraffin), Immunofluorescence
Clone:
SPM617
Dilution:
Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Paraffin, Flow (Cell Surface), Immunofluorescence
Gene Alias:
beta chain of MHC class I molecules, beta-2-microglobin, beta-2-microglobulin
Host Species:
Mouse
Quantity:
0.1 mL
Gene ID (Entrez):
567.0
Target Species:
Human, Primate
Isotype:
IgG1 κ
Antigen: beta 2-Microglobulin
Classification: Monoclonal
Conjugate: Alexa Fluor 594
Formulation: 50 mM sodium borate with 0.05% sodium azide
Gene Symbols: B2M
Immunogen: Full length recombinant human beta 2-Microglobulin protein (Uniprot: P61769)
Primary or Secondary: Primary
Test Specificity: Beta2 microglobulin is a 12KDa protein with a pI of 5.6. Serum beta2 microglobulin levels are a reflection of cell turnover. Levels rise with fever, inflammation, and infection. Increased serum levels are also seen in B-cell malignancies and in renal failure and may indicate a worse prognosis for patients with early-stage Hodgkin′s lymphoma. In urine, increased levels are seen in proximal renal tubular disease as well as renal transplant rejection. Beta2 microglobulin levels can rise either because its rate of synthesis has increased (e.g. in AIDS, malignant monoclonal plasma cell dyscrasia, solid tumours and autoimmune disease) or because of impaired renal filtration (e.g. due to renal insufficiency, graft rejection or nephrotoxicity induced by post-transplantation immunosuppressive therapy)
Content And Storage: Store at 4°C in the dark.
Applications: Flow Cytometry, Immunohistochemistry, Immunohistochemistry (Paraffin), Immunofluorescence
Clone: SPM617
Dilution: Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Paraffin, Flow (Cell Surface), Immunofluorescence
Gene Alias: beta chain of MHC class I molecules, beta-2-microglobin, beta-2-microglobulin
Host Species: Mouse
Quantity: 0.1 mL
Gene ID (Entrez): 567.0
Target Species: Human, Primate
Isotype: IgG1 κ
Antigen:
beta 2-Microglobulin
Classification:
Monoclonal
Conjugate:
Alexa Fluor 594
Formulation:
50 mM sodium borate with 0.05% sodium azide
Gene Symbols:
B2M
Immunogen:
Full length recombinant human beta 2-Microglobulin protein (Uniprot: P61769)
Primary or Secondary:
Primary
Test Specificity:
Beta2 microglobulin is a 12KDa protein with a pI of 5.6. Serum beta2 microglobulin levels are a reflection of cell turnover. Levels rise with fever, inflammation, and infection. Increased serum levels are also seen in B-cell malignancies and in renal failure and may indicate a worse prognosis for patients with early-stage Hodgkin′s lymphoma. In urine, increased levels are seen in proximal renal tubular disease as well as renal transplant rejection. Beta2 microglobulin levels can rise either because its rate of synthesis has increased (e.g. in AIDS, malignant monoclonal plasma cell dyscrasia, solid tumours and autoimmune disease) or because of impaired renal filtration (e.g. due to renal insufficiency, graft rejection or nephrotoxicity induced by post-transplantation immunosuppressive therapy)
Content And Storage:
Store at 4°C in the dark.
Applications:
Flow Cytometry, Immunohistochemistry, Immunohistochemistry (Paraffin), Immunofluorescence
Clone:
SPM617
Dilution:
Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Paraffin, Flow (Cell Surface), Immunofluorescence
Gene Alias:
beta chain of MHC class I molecules, beta-2-microglobin, beta-2-microglobulin
Host Species:
Mouse
Quantity:
0.1 mL
Gene ID (Entrez):
567.0
Target Species:
Human, Primate
Isotype:
IgG1 κ
Antigen: beta 2-Microglobulin
Classification: Monoclonal
Conjugate: Alexa Fluor 350
Formulation: 50 mM sodium borate with 0.05% sodium azide
Gene Symbols: B2M
Immunogen: Full length recombinant human beta 2-Microglobulin protein (Uniprot: P61769 )
Primary or Secondary: Primary
Test Specificity: Recognizes a protein of 12kDa, identified as beta-2 microglobulin. Major histocompatibility complex (MHC) class 1 molecules bind to antigens for presentation on the surface of cells. The proteasome is responsible for producing these antigens from the components of foreign pathogens. MHC class 1 molecules consist of an alpha heavy chain that contains three subdomains (alpha1, alpha2, alpha3) and a non-covalent associating light chain, known as beta-2-Microglobulin. beta-2-Microglobulin associates with the alpha3 subdomain of the alpha heavy chain and forms an immunoglobulin domain-like structure that mediates proper folding and expression of MHC class 1 molecules. The alpha1 and alpha2 domains of the alpha heavy chain form the peptide antigen-binding cleft. Mutations in the beta-2-Microglobulin gene can enhance the progression of malignant melanoma phenotypes.
Content And Storage: Store at 4°C in the dark.
Applications: Flow Cytometry, Immunohistochemistry, Immunohistochemistry (Paraffin), Immunofluorescence
Clone: B2M/961
Dilution: Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Paraffin, Flow (Cell Surface), Immunofluorescence
Gene Alias: beta chain of MHC class I molecules, beta-2-microglobin, beta-2-microglobulin
Host Species: Mouse
Quantity: 0.1 mL
Gene ID (Entrez): 567.0
Target Species: Human, Primate
Isotype: IgG2b κ
Antigen:
beta 2-Microglobulin
Classification:
Monoclonal
Conjugate:
Alexa Fluor 350
Formulation:
50 mM sodium borate with 0.05% sodium azide
Gene Symbols:
B2M
Immunogen:
Full length recombinant human beta 2-Microglobulin protein (Uniprot: P61769 )
Primary or Secondary:
Primary
Test Specificity:
Recognizes a protein of 12kDa, identified as beta-2 microglobulin. Major histocompatibility complex (MHC) class 1 molecules bind to antigens for presentation on the surface of cells. The proteasome is responsible for producing these antigens from the components of foreign pathogens. MHC class 1 molecules consist of an alpha heavy chain that contains three subdomains (alpha1, alpha2, alpha3) and a non-covalent associating light chain, known as beta-2-Microglobulin. beta-2-Microglobulin associates with the alpha3 subdomain of the alpha heavy chain and forms an immunoglobulin domain-like structure that mediates proper folding and expression of MHC class 1 molecules. The alpha1 and alpha2 domains of the alpha heavy chain form the peptide antigen-binding cleft. Mutations in the beta-2-Microglobulin gene can enhance the progression of malignant melanoma phenotypes.
Content And Storage:
Store at 4°C in the dark.
Applications:
Flow Cytometry, Immunohistochemistry, Immunohistochemistry (Paraffin), Immunofluorescence
Clone:
B2M/961
Dilution:
Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Paraffin, Flow (Cell Surface), Immunofluorescence
Gene Alias:
beta chain of MHC class I molecules, beta-2-microglobin, beta-2-microglobulin
Host Species:
Mouse
Quantity:
0.1 mL
Gene ID (Entrez):
567.0
Target Species:
Human, Primate
Isotype:
IgG2b κ