NP247806A70

PD-1 Antibody (SPM597), Alexa Fluor™ 750, Novus Biologicals™

Manufacturer: Novus Biologicals

Select a Size

Pack Size SKU Availability Price
Each of 1 NP247806A70-Each-of-1 In Stock ₹ 56,298.48

NP247806A70 - Each of 1

₹ 56,298.48

In Stock

Quantity

1

Base Price: ₹ 56,298.48

GST (18%): ₹ 10,133.726

Total Price: ₹ 66,432.206

Antigen

PD-1

Classification

Monoclonal

Conjugate

Alexa Fluor 750

Formulation

50 mM sodium borate with 0.05% sodium azide

Gene Symbols

PDCD1

Immunogen

Recombinant full-length human PD-1 protein (Uniprot: Q15116)

Primary or Secondary

Primary

Test Specificity

PDCD-1 (programmed cell death-1 protein), also designated CD279, is a type I transmembrane receptor and a member of the immunoglobin gene superfamily. It is expressed on activated T-cells, B-cells, and myeloid cells. Anti-PDCD-1 is a marker of angioimmunoblastic lymphoma and suggests a unique cell of origin for this neoplasm. Unlike CD10 and BCL6, PDCD-1 is expressed by few B-cells, so anti-PDCD-1 may be a more specific and useful diagnostic marker in angioimmunoblastic lymphoma. In addition, PDCD-1 expression provides evidence that angioimmunoblastic lymphoma is a neoplasm derived from germinal center-associated T-cells.

Content And Storage

Store at 4°C in the dark.

Applications

Flow Cytometry, Immunohistochemistry, Immunohistochemistry (Paraffin), Immunofluorescence

Clone

SPM597

Dilution

Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Paraffin, Immunofluorescence

Gene Alias

CD279, CD279 antigen, hPD-1, PD1hPD-l, programmed cell death 1, programmed cell death protein 1, Protein PD-1, SLEB2

Host Species

Mouse

Quantity

0.1 mL

Gene ID (Entrez)

5133

Target Species

Human

Isotype

IgG1 κ

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Description

  • PD-1 Monoclonal specifically detects PD-1 in Human samples
  • It is validated for Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunofluorescence.

Compare Similar Items

Show Difference

Img

Novus Biologicals

NP247806A70

--


Antigen:
PD-1

Classification:
Monoclonal

Conjugate:
Alexa Fluor 750

Formulation:
50 mM sodium borate with 0.05% sodium azide

Gene Symbols:
PDCD1

Immunogen:
Recombinant full-length human PD-1 protein (Uniprot: Q15116)

Primary or Secondary:
Primary

Test Specificity:
PDCD-1 (programmed cell death-1 protein), also designated CD279, is a type I transmembrane receptor and a member of the immunoglobin gene superfamily. It is expressed on activated T-cells, B-cells, and myeloid cells. Anti-PDCD-1 is a marker of angioimmunoblastic lymphoma and suggests a unique cell of origin for this neoplasm. Unlike CD10 and BCL6, PDCD-1 is expressed by few B-cells, so anti-PDCD-1 may be a more specific and useful diagnostic marker in angioimmunoblastic lymphoma. In addition, PDCD-1 expression provides evidence that angioimmunoblastic lymphoma is a neoplasm derived from germinal center-associated T-cells.

Content And Storage:
Store at 4°C in the dark.

Applications:
Flow Cytometry, Immunohistochemistry, Immunohistochemistry (Paraffin), Immunofluorescence

Clone:
SPM597

Dilution:
Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Paraffin, Immunofluorescence

Gene Alias:
CD279, CD279 antigen, hPD-1, PD1hPD-l, programmed cell death 1, programmed cell death protein 1, Protein PD-1, SLEB2

Host Species:
Mouse

Quantity:
0.1 mL

Gene ID (Entrez):
5133

Target Species:
Human

Isotype:
IgG1 κ

Img

Novus Biologicals

NP247806A94

--


Antigen:
PD-1

Classification:
Monoclonal

Conjugate:
Alexa Fluor 594

Formulation:
50 mM sodium borate with 0.05% sodium azide

Gene Symbols:
PDCD1

Immunogen:
Recombinant full-length human PD-1 protein (Uniprot: Q15116)

Primary or Secondary:
Primary

Test Specificity:
PDCD-1 (programmed cell death-1 protein), also designated CD279, is a type I transmembrane receptor and a member of the immunoglobin gene superfamily. It is expressed on activated T-cells, B-cells, and myeloid cells. Anti-PDCD-1 is a marker of angioimmunoblastic lymphoma and suggests a unique cell of origin for this neoplasm. Unlike CD10 and BCL6, PDCD-1 is expressed by few B-cells, so anti-PDCD-1 may be a more specific and useful diagnostic marker in angioimmunoblastic lymphoma. In addition, PDCD-1 expression provides evidence that angioimmunoblastic lymphoma is a neoplasm derived from germinal center-associated T-cells.

Content And Storage:
Store at 4°C in the dark.

Applications:
Flow Cytometry, Immunohistochemistry, Immunohistochemistry (Paraffin), Immunofluorescence

Clone:
SPM597

Dilution:
Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Paraffin, Immunofluorescence

Gene Alias:
CD279, CD279 antigen, hPD-1, PD1hPD-l, programmed cell death 1, programmed cell death protein 1, Protein PD-1, SLEB2

Host Species:
Mouse

Quantity:
0.1 mL

Gene ID (Entrez):
5133

Target Species:
Human

Isotype:
IgG1 κ

Img

Novus Biologicals

NP247807A30

--


Antigen:
MVP

Classification:
Monoclonal

Conjugate:
Alexa Fluor 350

Formulation:
50 mM sodium borate with 0.05% sodium azide

Gene Symbols:
MVP

Immunogen:
Proteins precipitated from human breast cancer MCF-7 cells

Primary or Secondary:
Primary

Test Specificity:
Recognizes a protein of 104kDa-110kDa, characterized as major vault protein (MVP). Vaults are large ribonucleoprotein particles (RNPs) present in all eukaryotic cells. They have a complex morphology, including several small molecules of RNA, but a single protein species. The MVP accounts for >70% of their mass. Their shape is reminiscent of the nucleopore central plug. Treatment of cells with estradiol increases the amount of MVP in nuclear extract. The hormone-dependent interaction of vaults with ER is prevented in vitro by sodium molybdate. Antibodies to estrogen, progesterone and glucocorticoid receptors are able to co-immunoprecipitate the MVP. MVP is overexpressed in many neoplastic tissues and cell lines. Expression of MVP predicts a poor response to chemotherapy.

Content And Storage:
Store at 4°C in the dark.

Applications:
Flow Cytometry, Immunohistochemistry, Immunohistochemistry (Paraffin), Immunofluorescence

Clone:
1032

Dilution:
Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Paraffin, Immunofluorescence

Gene Alias:
LRPVAULT1, Lung resistance-related protein, major vault protein

Host Species:
Mouse

Quantity:
0.1 mL

Gene ID (Entrez):
9961

Target Species:
Human

Isotype:
IgG1 κ

Img

Novus Biologicals

NP247807A70

--


Antigen:
MVP

Classification:
Monoclonal

Conjugate:
Alexa Fluor 750

Formulation:
50 mM sodium borate with 0.05% sodium azide

Gene Symbols:
MVP

Immunogen:
Proteins precipitated from human breast cancer MCF-7 cells

Primary or Secondary:
Primary

Test Specificity:
Recognizes a protein of 104kDa-110kDa, characterized as major vault protein (MVP). Vaults are large ribonucleoprotein particles (RNPs) present in all eukaryotic cells. They have a complex morphology, including several small molecules of RNA, but a single protein species. The MVP accounts for >70% of their mass. Their shape is reminiscent of the nucleopore central plug. Treatment of cells with estradiol increases the amount of MVP in nuclear extract. The hormone-dependent interaction of vaults with ER is prevented in vitro by sodium molybdate. Antibodies to estrogen, progesterone and glucocorticoid receptors are able to co-immunoprecipitate the MVP. MVP is overexpressed in many neoplastic tissues and cell lines. Expression of MVP predicts a poor response to chemotherapy.

Content And Storage:
Store at 4°C in the dark.

Applications:
Flow Cytometry, Immunohistochemistry, Immunohistochemistry (Paraffin), Immunofluorescence

Clone:
1032

Dilution:
Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Paraffin, Immunofluorescence

Gene Alias:
LRPVAULT1, Lung resistance-related protein, major vault protein

Host Species:
Mouse

Quantity:
0.1 mL

Gene ID (Entrez):
9961.0

Target Species:
Human

Isotype:
IgG1 κ