NP247921A30

Cyclin D1 Antibody (CCND1/809), Alexa Fluor™ 350, Novus Biologicals™

Manufacturer: Novus Biologicals

Select a Size

Pack Size SKU Availability Price
Each of 1 NP247921A30-Each-of-1 In Stock ₹ 55,271.76

NP247921A30 - Each of 1

₹ 55,271.76

In Stock

Quantity

1

Base Price: ₹ 55,271.76

GST (18%): ₹ 9,948.917

Total Price: ₹ 65,220.677

Antigen

Cyclin D1

Classification

Monoclonal

Conjugate

Alexa Fluor 350

Formulation

50 mM sodium borate with 0.05% sodium azide

Gene Symbols

CCND1

Immunogen

Recombinant human Cyclin D1 protein (Uniprot: P24385)

Quantity

0.1 mL

Primary or Secondary

Primary

Test Specificity

Recognizes a protein of 36kDa, identified as cyclin D1. Cyclin D1, one of the key cell cycle regulators, is a putative proto-oncogene overexpressed in a wide variety of human neoplasms. This antibody neutralizes the activity of cyclin D1 in vivo. About 60% of mantle cell lymphomas (MCL) contain a t(11; 14)(q13; q32) translocation resulting in over-expression of cyclin D1. This antibody is useful in identifying mantle cell lymphomas (cyclin D1 positive) from CLL/SLL and follicular lymphomas (cyclin D1 negative). Occasionally, hairy cell leukemia and plasma cell myeloma weakly express Cyclin D1.

Content And Storage

Store at 4°C in the dark.

Applications

Western Blot, Flow Cytometry, Immunohistochemistry, Immunohistochemistry (Paraffin), Immunofluorescence

Clone

CCND1/809

Dilution

Western Blot, Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Paraffin, Immunofluorescence

Gene Alias

B-cell lymphoma 1 protein, BCL-1, BCL-1 oncogene, BCL1D11S287E, cyclin D1, cyclin D1 (PRAD1: parathyroid adenomatosis 1), G1/S-specific cyclin D1, G1/S-specific cyclin-D1, PRAD1 oncogene, PRAD1B-cell CLL/lymphoma 1, U21B31

Host Species

Mouse

Purification Method

Protein A or G purified

Research Discipline

Cancer, Cell Cycle and Replication, Core ESC Like Genes, mTOR Pathway, Stem Cell Markers, Wnt Signaling Pathway

Gene ID (Entrez)

595.0

Target Species

Human

Isotype

IgG2a κ

Related Products

Img

Novus Biologicals

NP247893A30

--

Img

Novus Biologicals

NP24782A94

--

Img

Novus Biologicals

NP24783A70

--

Img

Novus Biologicals

NP247879A30

--

Img

Novus Biologicals

NP23493A32

--

Img

Novus Biologicals

NP23493A70

--

Img

Novus Biologicals

NP23493A94

--

Img

Novus Biologicals

NP247879A94

--

Description

  • Cyclin D1 Monoclonal specifically detects Cyclin D1 in Human samples
  • It is validated for Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Paraffin.

Compare Similar Items

Show Difference

Img

Novus Biologicals

NP247921A30

--


Antigen:
Cyclin D1

Classification:
Monoclonal

Conjugate:
Alexa Fluor 350

Formulation:
50 mM sodium borate with 0.05% sodium azide

Gene Symbols:
CCND1

Immunogen:
Recombinant human Cyclin D1 protein (Uniprot: P24385)

Quantity:
0.1 mL

Primary or Secondary:
Primary

Test Specificity:
Recognizes a protein of 36kDa, identified as cyclin D1. Cyclin D1, one of the key cell cycle regulators, is a putative proto-oncogene overexpressed in a wide variety of human neoplasms. This antibody neutralizes the activity of cyclin D1 in vivo. About 60% of mantle cell lymphomas (MCL) contain a t(11; 14)(q13; q32) translocation resulting in over-expression of cyclin D1. This antibody is useful in identifying mantle cell lymphomas (cyclin D1 positive) from CLL/SLL and follicular lymphomas (cyclin D1 negative). Occasionally, hairy cell leukemia and plasma cell myeloma weakly express Cyclin D1.

Content And Storage:
Store at 4°C in the dark.

Applications:
Western Blot, Flow Cytometry, Immunohistochemistry, Immunohistochemistry (Paraffin), Immunofluorescence

Clone:
CCND1/809

Dilution:
Western Blot, Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Paraffin, Immunofluorescence

Gene Alias:
B-cell lymphoma 1 protein, BCL-1, BCL-1 oncogene, BCL1D11S287E, cyclin D1, cyclin D1 (PRAD1: parathyroid adenomatosis 1), G1/S-specific cyclin D1, G1/S-specific cyclin-D1, PRAD1 oncogene, PRAD1B-cell CLL/lymphoma 1, U21B31

Host Species:
Mouse

Purification Method:
Protein A or G purified

Research Discipline:
Cancer, Cell Cycle and Replication, Core ESC Like Genes, mTOR Pathway, Stem Cell Markers, Wnt Signaling Pathway

Gene ID (Entrez):
595.0

Target Species:
Human

Isotype:
IgG2a κ

Img

Novus Biologicals

NP247922A32

--


Antigen:
Pax7

Classification:
Monoclonal

Conjugate:
Alexa Fluor 532

Formulation:
50 mM sodium borate with 0.05% sodium azide

Gene Symbols:
PAX7

Immunogen:
Recombinant fragment (aa301-505) of human Pax7 protein (exact sequence is proprietary) (Uniprot: P23759)

Quantity:
0.1 mL

Primary or Secondary:
Primary

Test Specificity:
The Pax gene family of nuclear transcription factors is comprised of nine members that function during embryogenesis to regulate the temporal and position-dependent differentiation of cells. In addition, the family is involved in a variety of signal transduction pathways in the adult organism. Mutations in the Pax family of proteins have been linked to disease and cancer in humans. Pax-7 is a protein specifically expressed in cultured satellite cell-derived myoblasts. In situ hybridization reveals that Pax-7 is also expressed in satellite cells residing in adult muscle. A chromosomal aberration in the gene encoding Pax-7 causes rhabdomyosarcoma 2 (RMS2) (also called alveolar rhabdomyosarcoma).

Content And Storage:
Store at 4°C in the dark.

Applications:
Immunohistochemistry, Immunohistochemistry (Paraffin)

Clone:
PAX7/1187

Dilution:
Immunohistochemistry, Immunohistochemistry-Paraffin

Gene Alias:
FLJ37460, HuP1, paired box 7, paired box gene 7, paired box homeotic gene 7, paired box protein Pax-7, paired domain gene 7, PAX7 transcriptional factor, PAX7B, RMS2

Host Species:
Mouse

Purification Method:
Protein A or G purified

Research Discipline:
Apoptosis, Mesenchymal Stem Cell Markers, Stem Cell Markers

Gene ID (Entrez):
5081.0

Target Species:
Human

Isotype:
IgG1 κ

Img

Novus Biologicals

NP247922A70

--


Antigen:
Pax7

Classification:
Monoclonal

Conjugate:
Alexa Fluor 750

Formulation:
50 mM sodium borate with 0.05% sodium azide

Gene Symbols:
PAX7

Immunogen:
Recombinant fragment (aa301-505) of human Pax7 protein (exact sequence is proprietary) (Uniprot: P23759)

Quantity:
0.1 mL

Primary or Secondary:
Primary

Test Specificity:
The Pax gene family of nuclear transcription factors is comprised of nine members that function during embryogenesis to regulate the temporal and position-dependent differentiation of cells. In addition, the family is involved in a variety of signal transduction pathways in the adult organism. Mutations in the Pax family of proteins have been linked to disease and cancer in humans. Pax-7 is a protein specifically expressed in cultured satellite cell-derived myoblasts. In situ hybridization reveals that Pax-7 is also expressed in satellite cells residing in adult muscle. A chromosomal aberration in the gene encoding Pax-7 causes rhabdomyosarcoma 2 (RMS2) (also called alveolar rhabdomyosarcoma).

Content And Storage:
Store at 4°C in the dark.

Applications:
Immunohistochemistry, Immunohistochemistry (Paraffin)

Clone:
PAX7/1187

Dilution:
Immunohistochemistry, Immunohistochemistry-Paraffin

Gene Alias:
FLJ37460, HuP1, paired box 7, paired box gene 7, paired box homeotic gene 7, paired box protein Pax-7, paired domain gene 7, PAX7 transcriptional factor, PAX7B, RMS2

Host Species:
Mouse

Purification Method:
__

Research Discipline:
__

Gene ID (Entrez):
5081

Target Species:
Human

Isotype:
IgG1 κ

Img

Novus Biologicals

NP247922A94

--


Antigen:
Pax7

Classification:
Monoclonal

Conjugate:
Alexa Fluor 594

Formulation:
50 mM sodium borate with 0.05% sodium azide

Gene Symbols:
PAX7

Immunogen:
Recombinant fragment (aa301-505) of human Pax7 protein (exact sequence is proprietary) (Uniprot: P23759)

Quantity:
0.1 mL

Primary or Secondary:
Primary

Test Specificity:
The Pax gene family of nuclear transcription factors is comprised of nine members that function during embryogenesis to regulate the temporal and position-dependent differentiation of cells. In addition, the family is involved in a variety of signal transduction pathways in the adult organism. Mutations in the Pax family of proteins have been linked to disease and cancer in humans. Pax-7 is a protein specifically expressed in cultured satellite cell-derived myoblasts. In situ hybridization reveals that Pax-7 is also expressed in satellite cells residing in adult muscle. A chromosomal aberration in the gene encoding Pax-7 causes rhabdomyosarcoma 2 (RMS2) (also called alveolar rhabdomyosarcoma).

Content And Storage:
Store at 4°C in the dark.

Applications:
Immunohistochemistry, Immunohistochemistry (Paraffin)

Clone:
PAX7/1187

Dilution:
Immunohistochemistry, Immunohistochemistry-Paraffin

Gene Alias:
FLJ37460, HuP1, paired box 7, paired box gene 7, paired box homeotic gene 7, paired box protein Pax-7, paired domain gene 7, PAX7 transcriptional factor, PAX7B, RMS2

Host Species:
Mouse

Purification Method:
Protein A or G purified

Research Discipline:
Apoptosis, Mesenchymal Stem Cell Markers, Stem Cell Markers

Gene ID (Entrez):
5081.0

Target Species:
Human

Isotype:
IgG1 κ