OPA104050

Tyrosine Hydroxylase Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 OPA104050-Each-of-1 In Stock ₹ 50,565.96

OPA104050 - Each of 1

₹ 50,565.96

In Stock

Quantity

1

Base Price: ₹ 50,565.96

GST (18%): ₹ 9,101.873

Total Price: ₹ 59,667.833

Antigen

Tyrosine Hydroxylase

Classification

Polyclonal

Formulation

0.01M HEPES with 0.15M NaCl, 0.1mg/mL BSA, 50% glycerol and no preservative; pH 7.5

Gene Accession No.

P04177, P07101, P24529

Gene Symbols

TH

Immunogen

SDS-denatured, native rat tyrosine hydroxylase purified from pheochromocytoma

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Multi-species, Mouse, Rat

Product Type

Antibody

Isotype

IgG

Applications

Immunocytochemistry, Immunohistochemistry, Immunohistochemistry (Frozen), Western Blot

Conjugate

Unconjugated

Gene

TH

Gene Alias

dystonia 14; DYT14; DYT5b; EC 1.14.16.2; HGNC:11782; Th; TH isoform 3; TH isoform a; th1; TH-4; The; TY3H; TYH; TYH antibody; Tyrosine 3-hydroxylase; tyrosine 3-monooxygenase; tyrosine hydroxylase

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

21823, 25085, 7054

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Related Products

Img

Thermo Scientific

PA131402

--

Img

Thermo Scientific

PA126793

--

Img

Thermo Scientific

MA181819

--

Img

Thermo Scientific

MA183365

--

Img

Thermo Scientific

MA1932

--

Img

Thermo Scientific

MA180331

--

Img

Thermo Scientific

MA146412

--

Img

Thermo Scientific

PA130675

--

Description

  • In Western blot, this antibody detects a single ∽60 kDa protein representing tyrosine hydroxylase from rat brain lysates of PC-12 cells stimulated by okadaic acid
  • Immunohistochemical staining of TH in human brain with OPA1-04050 results in intense labeling of the dopaminergic neurons in the substantia nigra
  • Store at -20oC short term, 80oC long term
  • Tyrosine hydroxylase (TH) is an enzyme involved in the synthesis of catecholamine neurotransmitters dopamine, epinephrine, and norepinephrine
  • In all species, catecholamine synthesis is regulated by the interaction of TH with a cofactor, tetrahydrobiopterin (BH4)
  • BH4 binds to the TH catalytic domain, resulting in enzymatic activity
  • Unlike TH in non-primate species, four human TH mRNA splice variants (hTH1-hTH4) have been isolated
  • These variants are identical in their catalytic domain, but differ in their N-terminal, regulatory domains
  • TH is also responsible for the conversion of L-tyrosine to L-dopa
  • TH plays a key role in the physiology of adrenergic neurons
  • The role of TH in the synthesis of catecholamine neurotransmitters suggests a correlation between the enzyme and a number of neuropathogenic diseases including: Parkinson's disease, schizophrenia, Segawa syndrome, and dystonia, as well as a variety of cardiovascular diseases.

Compare Similar Items

Show Difference

Img

Thermo Scientific

OPA104050

--


Antigen:
Tyrosine Hydroxylase

Classification:
Polyclonal

Formulation:
0.01M HEPES with 0.15M NaCl, 0.1mg/mL BSA, 50% glycerol and no preservative; pH 7.5

Gene Accession No.:
P04177, P07101, P24529

Gene Symbols:
TH

Immunogen:
SDS-denatured, native rat tyrosine hydroxylase purified from pheochromocytoma

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Multi-species, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunocytochemistry, Immunohistochemistry, Immunohistochemistry (Frozen), Western Blot

Conjugate:
Unconjugated

Gene:
TH

Gene Alias:
dystonia 14; DYT14; DYT5b; EC 1.14.16.2; HGNC:11782; Th; TH isoform 3; TH isoform a; th1; TH-4; The; TY3H; TYH; TYH antibody; Tyrosine 3-hydroxylase; tyrosine 3-monooxygenase; tyrosine hydroxylase

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
21823, 25085, 7054

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Thermo Scientific

OPA104060

--


Antigen:
mGluR1

Classification:
Polyclonal

Formulation:
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and no preservative; pH 7.5

Gene Accession No.:
P23385, P97772

Gene Symbols:
Grm1

Immunogen:
Synthetic peptide corresponding to the C-terminal region of rat GRM1 conjugated to KLH

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunohistochemistry, Western Blot

Conjugate:
Unconjugated

Gene:
Grm1

Gene Alias:
4930455H15Rik; ENSMUSG00000075319; G protein coupled receptor family C group 1 member A; G protein coupled receptor, family C, group 1, member A; G protein-coupled receptor, family C, group 1, member A; glutamate metabotropic receptor 1; glutamate receptor; glutamate receptor, metabotropic 1; Gm10828; GPRC1A; GRM1; GRM1A; Metabotropic glutamate receptor 1; MGLU1; MGLUR1; mGluR1a; nmf373; PPP1R85; protein phosphatase 1, regulatory subunit 85; rcw; SCAR13; wobl

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
14816, 24414

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Thermo Scientific

OPA104111

--


Antigen:
GABRG2

Classification:
Polyclonal

Formulation:
whole serum with no preservative

Gene Accession No.:
P18508, P22723

Gene Symbols:
Gabrg2

Immunogen:
Synthetic peptide corresponding to amino acid residues specific to the gamma 2 subunit of rat GABRG2 conjugated to KLH

Quantity:
50 μL

Primary or Secondary:
Primary

Target Species:
Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunohistochemistry, Western Blot

Conjugate:
Unconjugated

Gene:
Gabrg2

Gene Alias:
CAE2, ECA2, GABA(A) receptor subunit gamma-2, GABA(A) receptor, gamma 2, GABAA-R, GABRA2, Gabrg2, Gabrg-2, gamma2, gamma-aminobutyrate receptor type A gamma-2 subuni, gamma-aminobutyric acid, gamma-aminobutyric acid A receptor, gamma 2, gamma-aminobutyric acid (GABA) A receptor, gamma 2, gamma-aminobutyric acid (GABA) A receptor, subunit gamma 2, gamma-aminobutyric acid (GABA-A) receptor, subunit gamma 2, gamma-aminobutyric acid A receptor gamma 2, gamma-aminobutyric acid A receptor, gamma 2, gamma-aminobutyric acid receptor subunit gamma-2, gamma-aminobutyric acid type A receptor gamma2 subunit, gamma-aminobutyric acid type A receptor subunit gamma2, GEFSP3, LOC553402 protein, LOW QUALITY PROTEIN: gamma-aminobutyric acid receptor subunit gamma-2, si:ch211-145n14.1

Host Species:
Rabbit

Purification Method:
__

Regulatory Status:
RUO

Gene ID (Entrez):
14406, 29709

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Thermo Scientific

OPA104114

--


Antigen:
GABRA6

Classification:
Polyclonal

Formulation:
whole serum with no preservative

Gene Accession No.:
P16305, P30191

Gene Symbols:
Gabra6

Immunogen:
Synthetic peptide corresponding to amino acid residues specific to the alpha 6 subunit of rat GABRA6 conjugated to KLH

Quantity:
50 μL

Primary or Secondary:
Primary

Target Species:
Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Western Blot

Conjugate:
Unconjugated

Gene:
Gabra6

Gene Alias:
alpha6, GABA subunit A receptor alpha 6, GABA(A) receptor subunit alpha-6, GABA(A) receptor, alpha 6, GABA-A receptor alpha-6 subunit, GABAAR alpha6, GABA-ARalpha6, GABRA 6, Gabra6, Gabra-6, gamma-aminobutyric acid, gamma-aminobutyric acid A receptor, alpha 6, gamma-aminobutyric acid (GABA) A receptor, alpha 6, gamma-aminobutyric acid (GABA) A receptor, subunit alpha 6, gamma-aminobutyric acid (GABA-A) receptor, subunit alpha 6, gamma-aminobutyric acid A receptor, alpha 6, gamma-aminobutyric acid receptor subunit alpha-6, gamma-aminobutyric acid type A receptor alpha6 subunit, subunit alpha 6 gamma-aminobutyric acid (GABA-A) receptor

Host Species:
Rabbit

Purification Method:
__

Regulatory Status:
RUO

Gene ID (Entrez):
14399, 29708

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid