OPA104114

GABRA6 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 OPA104114-Each-of-1 In Stock ₹ 44,705.10

OPA104114 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

GABRA6

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Gabra6

Gene Alias

alpha6, GABA subunit A receptor alpha 6, GABA(A) receptor subunit alpha-6, GABA(A) receptor, alpha 6, GABA-A receptor alpha-6 subunit, GABAAR alpha6, GABA-ARalpha6, GABRA 6, Gabra6, Gabra-6, gamma-aminobutyric acid, gamma-aminobutyric acid A receptor, alpha 6, gamma-aminobutyric acid (GABA) A receptor, alpha 6, gamma-aminobutyric acid (GABA) A receptor, subunit alpha 6, gamma-aminobutyric acid (GABA-A) receptor, subunit alpha 6, gamma-aminobutyric acid A receptor, alpha 6, gamma-aminobutyric acid receptor subunit alpha-6, gamma-aminobutyric acid type A receptor alpha6 subunit, subunit alpha 6 gamma-aminobutyric acid (GABA-A) receptor

Host Species

Rabbit

Quantity

50 μL

Primary or Secondary

Primary

Target Species

Mouse, Rat

Product Type

Antibody

Isotype

IgG

Applications

Western Blot

Concentration

Conc. Not Determined

Formulation

whole serum with no preservative

Gene Accession No.

P16305, P30191

Gene Symbols

Gabra6

Immunogen

Synthetic peptide corresponding to amino acid residues specific to the alpha 6 subunit of rat GABRA6 conjugated to KLH

Regulatory Status

RUO

Gene ID (Entrez)

14399, 29708

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

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Description

  • In Western blot, this antibody detects a ∽57 kDa protein representing GABA-A R alpha 6 subunit in rat brain lysate
  • The immunogenic sequence has no homology with any other GABA-A receptor subunits
  • Gamma-aminobutyric acid (GABA) is the primary inhibitory neurotransmitter in the central nervous system, causing a hyperpolarization of the membrane through the opening of a Cl- channel associated with the GABA-A Receptor (GABA-A R) Subtype
  • GABA-A Rs are important therapeutic targets for a range of sedative, anxiolytic, and hypnotic agents and are implicated in several diseases including epilepsy, anxiety, depression, and substance abuse
  • The GABA-A R is a multimeric subunit complex
  • To date six alphas, four betas and four gammas, plus alternative splicing variants of some of these subunits, have been identified
  • Injection in oocytes or mammalian cell lines of cRNA coding for alpha and beta subunits results in the expression of functional GABA-A Rs sensitive to GABA
  • However, coexpression of a gamma-subunit is required for benzodiazepine modulation
  • The various effects of the benzodiazepines in brain may also be mediated via different alpha subunits of the receptor
  • Lastly, phosphorylation of beta subunits of the receptor has been shown to modulate GABA-A R function.

Compare Similar Items

Show Difference

Img

Thermo Scientific

OPA104114

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Antigen:
GABRA6

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Gabra6

Gene Alias:
alpha6, GABA subunit A receptor alpha 6, GABA(A) receptor subunit alpha-6, GABA(A) receptor, alpha 6, GABA-A receptor alpha-6 subunit, GABAAR alpha6, GABA-ARalpha6, GABRA 6, Gabra6, Gabra-6, gamma-aminobutyric acid, gamma-aminobutyric acid A receptor, alpha 6, gamma-aminobutyric acid (GABA) A receptor, alpha 6, gamma-aminobutyric acid (GABA) A receptor, subunit alpha 6, gamma-aminobutyric acid (GABA-A) receptor, subunit alpha 6, gamma-aminobutyric acid A receptor, alpha 6, gamma-aminobutyric acid receptor subunit alpha-6, gamma-aminobutyric acid type A receptor alpha6 subunit, subunit alpha 6 gamma-aminobutyric acid (GABA-A) receptor

Host Species:
Rabbit

Quantity:
50 μL

Primary or Secondary:
Primary

Target Species:
Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Western Blot

Concentration:
Conc. Not Determined

Formulation:
whole serum with no preservative

Gene Accession No.:
P16305, P30191

Gene Symbols:
Gabra6

Immunogen:
Synthetic peptide corresponding to amino acid residues specific to the alpha 6 subunit of rat GABRA6 conjugated to KLH

Regulatory Status:
RUO

Gene ID (Entrez):
14399, 29708

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Thermo Scientific

OPA104116

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Antigen:
Phospho-NMDAR2B (Tyr1472)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
GRIN2B

Gene Alias:
AW490526; EIEE27; GluN2B; GluRepsilon2; glutamate [NMDA] receptor subunit epsilon-2; glutamate ionotropic receptor NMDA type subunit 2B; glutamate receptor; glutamate receptor ionotropic, NMDA 2B; glutamate receptor subunit epsilon-2; glutamate receptor, ionotropic, NMDA2B; glutamate receptor, ionotropic, NMDA2B (epsilon 2); glutamate receptor, ionotropic, N-methyl D-aspartate 2B; GRIN 2B; GRIN2B; HGNC:4586; hNR 3; hNR3; LOW QUALITY PROTEIN: glutamate receptor ionotropic, NMDA 2B; MGC142178; MGC142180; MRD6; Nmdar2b; NMDE2; NME2; N-methyl D-aspartate receptor 2B; N-methyl D-aspartate receptor subtype 2B; N-methyl-D-aspartate receptor subunit 2B; N-methyl-D-aspartate receptor subunit 3; NR2B; NR3

Host Species:
Rabbit

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunocytochemistry, Western Blot

Concentration:
__

Formulation:
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and no preservative; pH 7.5

Gene Accession No.:
Q00960, Q01097

Gene Symbols:
GRIN2B

Immunogen:
Synthetic phospho-peptide corresponding to amino acid residues surrounding Tyr1472 of rat GRIN2B conjugated to KLH

Regulatory Status:
RUO

Gene ID (Entrez):
14812, 24410

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Thermo Scientific

OPA110080

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Antigen:
p38 MAPK

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
MAPK14

Gene Alias:
Crk1; CSAID-binding protein; Csaids binding protein; CSBP; CSBP1; CSBP2; CSPB1; cytokine suppressive anti-inflammatory drug binding protein; cytokine suppressive anti-inflammatory drug binding protein 1; cytokine suppressive anti-inflammatory drug-binding protein; cytokine-supressive anti-inflammatory drug binding protein; Exip; Hog; MAP kinase 11; MAP kinase 13; MAP kinase 14; MAP kinase 2; MAP kinase Mxi2; MAP kinase p38 alpha; MAP kinase p38 beta; MAP kinase p38 delta; MAPK 11; MAPK 13; MAPK 14; Mapk11; Mapk13; MAPK-13; Mapk14; MAX-interacting protein 2; mitogen activated protein kinase 11; mitogen activated protein kinase 13; mitogen activated protein kinase 14; mitogen-activated protein kinase 11; Mitogen-activated protein kinase 13; mitogen-activated protein kinase 14; mitogen-activated protein kinase 14A; mitogen-activated protein kinase p38 alpha; Mitogen-activated protein kinase p38 beta; mitogen-activated protein kinase p38 delta; mitogen-activated protein kinase p38-2; MXI2; p38; p38 alpha; p38 delta MAP kinase; p38 MAP kinase; p38 MAP kinase alpha; p38 MAPK; p38 mitogen activated protein kinase; p38-2; p38a; p38ALPHA; p38-alpha; p38alpha Exip; P38b; p38Beta; p38beta2; p38delta; p38Hog; p38MAPK; Prkm11; PRKM13; PRKM14; Prkm15; protein kinase, mitogen activated kinase, 11, p38beta; reactive kinase; RK; SAPK/Erk/kinase 4; SAPK2; SAPK2A; SAPK2B; SAPK4; Serk4; Stress-activated protein kinase 2a; Stress-activated protein kinase 2b; Stress-activated protein kinase 4; stress-activated protein kinase-2; stress-activated protein kinase-2b; tRNA synthetase cofactor p38

Host Species:
Rabbit

Quantity:
1 mL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunocytochemistry, Immunohistochemistry (Frozen), Immunoprecipitation, Western Blot

Concentration:
0.2 mg/mL

Formulation:
PBS with 0.2% gelatin and 0.1% sodium azide

Gene Accession No.:
P47811, P70618, Q16539

Gene Symbols:
MAPK14

Immunogen:
Synthetic peptide corresponding to the carboxy terminal region of mouse p38.

Regulatory Status:
RUO

Gene ID (Entrez):
1432, 26416, 81649

Content And Storage:
4° C, do not freeze

Form:
Liquid

Img

Thermo Scientific

OPA110100

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Antigen:
EGFR

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
EGFR

Gene Alias:
2.7.10.1; 9030024J15Rik; AI552599; avian erythroblastic leukemia viral (v-erbB) oncogene homolog; avian erythroblastic leukemia viral (v-erb-b) oncogene homolog; cell growth inhibiting protein 40; cell proliferation-inducing protein 61; EC 2.7.10.1; egf receptor; Egfr; EGFR-related peptide; epidermal growth factor receptor; epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian); Epidermal growth factor receptor formerly avian erythroblastic leukemia viral (v-erbB) oncogene homolog (Erbb1); epidermal growth factor receptor, formerly avian erythroblastic leukemia viral (v-erbB) oncogene homolog (Erbb1); ERBB; ERBB1; ErbB-1; erb-b2 receptor tyrosine kinase 1; Errb1; Errp; HER1; kinase EGFR; mENA; NISBD2; Oncogene ERBB; PIG61; Proto-oncogene c-ErbB-1; receptor tyrosine-protein kinase erbB-1; Urogastrone; wa2; wa-2; Wa5; waved 2

Host Species:
Rabbit

Quantity:
1 mL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Concentration:
0.2 mg/mL

Formulation:
PBS with 0.2% gelatin and 0.1% sodium azide

Gene Accession No.:
P00533, Q01279

Gene Symbols:
EGFR

Immunogen:
Synthetic peptide corresponding to the carboxy terminal region of human EGFR.

Regulatory Status:
RUO

Gene ID (Entrez):
13649, 1956, 24329

Content And Storage:
4° C, do not freeze

Form:
Liquid