OPA104116
Phospho-NMDAR2B (Tyr1472) Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | OPA104116-Each-of-1 | In Stock | ₹ 47,357.46 |
OPA104116 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 47,357.46
GST (18%): ₹ 8,524.343
Total Price: ₹ 55,881.803
Antigen
Phospho-NMDAR2B (Tyr1472)
Classification
Polyclonal
Formulation
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and no preservative; pH 7.5
Gene Accession No.
Q00960, Q01097
Gene Symbols
GRIN2B
Immunogen
Synthetic phospho-peptide corresponding to amino acid residues surrounding Tyr1472 of rat GRIN2B conjugated to KLH
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Mouse, Rat
Product Type
Antibody
Isotype
IgG
Applications
Immunocytochemistry, Western Blot
Conjugate
Unconjugated
Gene
GRIN2B
Gene Alias
AW490526; EIEE27; GluN2B; GluRepsilon2; glutamate [NMDA] receptor subunit epsilon-2; glutamate ionotropic receptor NMDA type subunit 2B; glutamate receptor; glutamate receptor ionotropic, NMDA 2B; glutamate receptor subunit epsilon-2; glutamate receptor, ionotropic, NMDA2B; glutamate receptor, ionotropic, NMDA2B (epsilon 2); glutamate receptor, ionotropic, N-methyl D-aspartate 2B; GRIN 2B; GRIN2B; HGNC:4586; hNR 3; hNR3; LOW QUALITY PROTEIN: glutamate receptor ionotropic, NMDA 2B; MGC142178; MGC142180; MRD6; Nmdar2b; NMDE2; NME2; N-methyl D-aspartate receptor 2B; N-methyl D-aspartate receptor subtype 2B; N-methyl-D-aspartate receptor subunit 2B; N-methyl-D-aspartate receptor subunit 3; NR2B; NR3
Host Species
Rabbit
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
14812, 24410
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Related Products
Description
- This antibody is predicted to react with bovine, canine, chicken, human, mouse, non-human primate and zebrafish based on 100% sequence homology
- In Western blot, this antibody detects a ∽180 kDa protein representing NMDAR NR2B-subunit protein phosphorylated at Tyr1472
- It also labels proteins of ∽65k and ∽115k
- Immunolabeling is completely blocked by blocked by either lamda-Ptase or by the phosphopeptide used as the antigen but not by the corresponding dephosphopeptide
- NMDAR2B is a member of the N-methyl-D-aspartate (NMDA) class of ionotropic glutamate receptors
- NMDA receptors (NMDAR) have been shown to be involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning
- NMDAR play a role in neuronal development and has been implicated in several disorders of the central nervous system including Alzheimer’s Disease, epilepsy and ischemic neuronal cell death
- Overexpression of the NR2B subunit of the receptor has been associated with increases in learning and memory while aged, memory impaired animals have deficiencies in NR2B expression
- Tyr1472 on NR2B is phosphorylated and this may lead to the increased expression of the NMDAR at the synapse that plays a role in synaptic plasticity
- NMDR2B is a heterotrimer comprised of seven enetically encoded and differentially expressed subunits that include NR1, NR2 and NR3
- Diseases associated with the dysfunction of NMDAR2B include epileptic encephalopathy, autosomal dominant 6-related mental retardation.
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Antigen: Phospho-NMDAR2B (Tyr1472)
Classification: Polyclonal
Formulation: 0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and no preservative; pH 7.5
Gene Accession No.: Q00960, Q01097
Gene Symbols: GRIN2B
Immunogen: Synthetic phospho-peptide corresponding to amino acid residues surrounding Tyr1472 of rat GRIN2B conjugated to KLH
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Mouse, Rat
Product Type: Antibody
Isotype: IgG
Applications: Immunocytochemistry, Western Blot
Conjugate: Unconjugated
Gene: GRIN2B
Gene Alias: AW490526; EIEE27; GluN2B; GluRepsilon2; glutamate [NMDA] receptor subunit epsilon-2; glutamate ionotropic receptor NMDA type subunit 2B; glutamate receptor; glutamate receptor ionotropic, NMDA 2B; glutamate receptor subunit epsilon-2; glutamate receptor, ionotropic, NMDA2B; glutamate receptor, ionotropic, NMDA2B (epsilon 2); glutamate receptor, ionotropic, N-methyl D-aspartate 2B; GRIN 2B; GRIN2B; HGNC:4586; hNR 3; hNR3; LOW QUALITY PROTEIN: glutamate receptor ionotropic, NMDA 2B; MGC142178; MGC142180; MRD6; Nmdar2b; NMDE2; NME2; N-methyl D-aspartate receptor 2B; N-methyl D-aspartate receptor subtype 2B; N-methyl-D-aspartate receptor subunit 2B; N-methyl-D-aspartate receptor subunit 3; NR2B; NR3
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 14812, 24410
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
Phospho-NMDAR2B (Tyr1472)
Classification:
Polyclonal
Formulation:
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and no preservative; pH 7.5
Gene Accession No.:
Q00960, Q01097
Gene Symbols:
GRIN2B
Immunogen:
Synthetic phospho-peptide corresponding to amino acid residues surrounding Tyr1472 of rat GRIN2B conjugated to KLH
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Applications:
Immunocytochemistry, Western Blot
Conjugate:
Unconjugated
Gene:
GRIN2B
Gene Alias:
AW490526; EIEE27; GluN2B; GluRepsilon2; glutamate [NMDA] receptor subunit epsilon-2; glutamate ionotropic receptor NMDA type subunit 2B; glutamate receptor; glutamate receptor ionotropic, NMDA 2B; glutamate receptor subunit epsilon-2; glutamate receptor, ionotropic, NMDA2B; glutamate receptor, ionotropic, NMDA2B (epsilon 2); glutamate receptor, ionotropic, N-methyl D-aspartate 2B; GRIN 2B; GRIN2B; HGNC:4586; hNR 3; hNR3; LOW QUALITY PROTEIN: glutamate receptor ionotropic, NMDA 2B; MGC142178; MGC142180; MRD6; Nmdar2b; NMDE2; NME2; N-methyl D-aspartate receptor 2B; N-methyl D-aspartate receptor subtype 2B; N-methyl-D-aspartate receptor subunit 2B; N-methyl-D-aspartate receptor subunit 3; NR2B; NR3
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
14812, 24410
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Antigen: p38 MAPK
Classification: Polyclonal
Formulation: PBS with 0.2% gelatin and 0.1% sodium azide
Gene Accession No.: P47811, P70618, Q16539
Gene Symbols: MAPK14
Immunogen: Synthetic peptide corresponding to the carboxy terminal region of mouse p38.
Quantity: 1 mL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Applications: Immunocytochemistry, Immunohistochemistry (Frozen), Immunoprecipitation, Western Blot
Conjugate: Unconjugated
Gene: MAPK14
Gene Alias: Crk1; CSAID-binding protein; Csaids binding protein; CSBP; CSBP1; CSBP2; CSPB1; cytokine suppressive anti-inflammatory drug binding protein; cytokine suppressive anti-inflammatory drug binding protein 1; cytokine suppressive anti-inflammatory drug-binding protein; cytokine-supressive anti-inflammatory drug binding protein; Exip; Hog; MAP kinase 11; MAP kinase 13; MAP kinase 14; MAP kinase 2; MAP kinase Mxi2; MAP kinase p38 alpha; MAP kinase p38 beta; MAP kinase p38 delta; MAPK 11; MAPK 13; MAPK 14; Mapk11; Mapk13; MAPK-13; Mapk14; MAX-interacting protein 2; mitogen activated protein kinase 11; mitogen activated protein kinase 13; mitogen activated protein kinase 14; mitogen-activated protein kinase 11; Mitogen-activated protein kinase 13; mitogen-activated protein kinase 14; mitogen-activated protein kinase 14A; mitogen-activated protein kinase p38 alpha; Mitogen-activated protein kinase p38 beta; mitogen-activated protein kinase p38 delta; mitogen-activated protein kinase p38-2; MXI2; p38; p38 alpha; p38 delta MAP kinase; p38 MAP kinase; p38 MAP kinase alpha; p38 MAPK; p38 mitogen activated protein kinase; p38-2; p38a; p38ALPHA; p38-alpha; p38alpha Exip; P38b; p38Beta; p38beta2; p38delta; p38Hog; p38MAPK; Prkm11; PRKM13; PRKM14; Prkm15; protein kinase, mitogen activated kinase, 11, p38beta; reactive kinase; RK; SAPK/Erk/kinase 4; SAPK2; SAPK2A; SAPK2B; SAPK4; Serk4; Stress-activated protein kinase 2a; Stress-activated protein kinase 2b; Stress-activated protein kinase 4; stress-activated protein kinase-2; stress-activated protein kinase-2b; tRNA synthetase cofactor p38
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 1432, 26416, 81649
Content And Storage: 4° C, do not freeze
Form: Liquid
Antigen:
p38 MAPK
Classification:
Polyclonal
Formulation:
PBS with 0.2% gelatin and 0.1% sodium azide
Gene Accession No.:
P47811, P70618, Q16539
Gene Symbols:
MAPK14
Immunogen:
Synthetic peptide corresponding to the carboxy terminal region of mouse p38.
Quantity:
1 mL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Applications:
Immunocytochemistry, Immunohistochemistry (Frozen), Immunoprecipitation, Western Blot
Conjugate:
Unconjugated
Gene:
MAPK14
Gene Alias:
Crk1; CSAID-binding protein; Csaids binding protein; CSBP; CSBP1; CSBP2; CSPB1; cytokine suppressive anti-inflammatory drug binding protein; cytokine suppressive anti-inflammatory drug binding protein 1; cytokine suppressive anti-inflammatory drug-binding protein; cytokine-supressive anti-inflammatory drug binding protein; Exip; Hog; MAP kinase 11; MAP kinase 13; MAP kinase 14; MAP kinase 2; MAP kinase Mxi2; MAP kinase p38 alpha; MAP kinase p38 beta; MAP kinase p38 delta; MAPK 11; MAPK 13; MAPK 14; Mapk11; Mapk13; MAPK-13; Mapk14; MAX-interacting protein 2; mitogen activated protein kinase 11; mitogen activated protein kinase 13; mitogen activated protein kinase 14; mitogen-activated protein kinase 11; Mitogen-activated protein kinase 13; mitogen-activated protein kinase 14; mitogen-activated protein kinase 14A; mitogen-activated protein kinase p38 alpha; Mitogen-activated protein kinase p38 beta; mitogen-activated protein kinase p38 delta; mitogen-activated protein kinase p38-2; MXI2; p38; p38 alpha; p38 delta MAP kinase; p38 MAP kinase; p38 MAP kinase alpha; p38 MAPK; p38 mitogen activated protein kinase; p38-2; p38a; p38ALPHA; p38-alpha; p38alpha Exip; P38b; p38Beta; p38beta2; p38delta; p38Hog; p38MAPK; Prkm11; PRKM13; PRKM14; Prkm15; protein kinase, mitogen activated kinase, 11, p38beta; reactive kinase; RK; SAPK/Erk/kinase 4; SAPK2; SAPK2A; SAPK2B; SAPK4; Serk4; Stress-activated protein kinase 2a; Stress-activated protein kinase 2b; Stress-activated protein kinase 4; stress-activated protein kinase-2; stress-activated protein kinase-2b; tRNA synthetase cofactor p38
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
1432, 26416, 81649
Content And Storage:
4° C, do not freeze
Form:
Liquid
Antigen: EGFR
Classification: Polyclonal
Formulation: PBS with 0.2% gelatin and 0.1% sodium azide
Gene Accession No.: P00533, Q01279
Gene Symbols: EGFR
Immunogen: Synthetic peptide corresponding to the carboxy terminal region of human EGFR.
Quantity: 1 mL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Applications: Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Conjugate: Unconjugated
Gene: EGFR
Gene Alias: 2.7.10.1; 9030024J15Rik; AI552599; avian erythroblastic leukemia viral (v-erbB) oncogene homolog; avian erythroblastic leukemia viral (v-erb-b) oncogene homolog; cell growth inhibiting protein 40; cell proliferation-inducing protein 61; EC 2.7.10.1; egf receptor; Egfr; EGFR-related peptide; epidermal growth factor receptor; epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian); Epidermal growth factor receptor formerly avian erythroblastic leukemia viral (v-erbB) oncogene homolog (Erbb1); epidermal growth factor receptor, formerly avian erythroblastic leukemia viral (v-erbB) oncogene homolog (Erbb1); ERBB; ERBB1; ErbB-1; erb-b2 receptor tyrosine kinase 1; Errb1; Errp; HER1; kinase EGFR; mENA; NISBD2; Oncogene ERBB; PIG61; Proto-oncogene c-ErbB-1; receptor tyrosine-protein kinase erbB-1; Urogastrone; wa2; wa-2; Wa5; waved 2
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 13649, 1956, 24329
Content And Storage: 4° C, do not freeze
Form: Liquid
Antigen:
EGFR
Classification:
Polyclonal
Formulation:
PBS with 0.2% gelatin and 0.1% sodium azide
Gene Accession No.:
P00533, Q01279
Gene Symbols:
EGFR
Immunogen:
Synthetic peptide corresponding to the carboxy terminal region of human EGFR.
Quantity:
1 mL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Applications:
Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Conjugate:
Unconjugated
Gene:
EGFR
Gene Alias:
2.7.10.1; 9030024J15Rik; AI552599; avian erythroblastic leukemia viral (v-erbB) oncogene homolog; avian erythroblastic leukemia viral (v-erb-b) oncogene homolog; cell growth inhibiting protein 40; cell proliferation-inducing protein 61; EC 2.7.10.1; egf receptor; Egfr; EGFR-related peptide; epidermal growth factor receptor; epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian); Epidermal growth factor receptor formerly avian erythroblastic leukemia viral (v-erbB) oncogene homolog (Erbb1); epidermal growth factor receptor, formerly avian erythroblastic leukemia viral (v-erbB) oncogene homolog (Erbb1); ERBB; ERBB1; ErbB-1; erb-b2 receptor tyrosine kinase 1; Errb1; Errp; HER1; kinase EGFR; mENA; NISBD2; Oncogene ERBB; PIG61; Proto-oncogene c-ErbB-1; receptor tyrosine-protein kinase erbB-1; Urogastrone; wa2; wa-2; Wa5; waved 2
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
13649, 1956, 24329
Content And Storage:
4° C, do not freeze
Form:
Liquid
Antigen: GIPR
Classification: Polyclonal
Formulation: PBS with 0.1% sodium azide
Gene Accession No.: P48546
Gene Symbols: GIPR
Immunogen: Synthetic peptide (KLH conjugated) to the N-terminus.
Quantity: 25 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Applications: Immunohistochemistry (Paraffin)
Conjugate: Unconjugated
Gene: GIPR
Gene Alias: gastric inhibitory peptide receptor; gastric inhibitory polypeptide receptor; GIP receptor; Gippr; Gipr; GIP-R; Glucose-dependent insulinotropic polypeptide receptor; Gm1081; Gm160; PGQTL2; RATGIPPR
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 2696
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
GIPR
Classification:
Polyclonal
Formulation:
PBS with 0.1% sodium azide
Gene Accession No.:
P48546
Gene Symbols:
GIPR
Immunogen:
Synthetic peptide (KLH conjugated) to the N-terminus.
Quantity:
25 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Applications:
Immunohistochemistry (Paraffin)
Conjugate:
Unconjugated
Gene:
GIPR
Gene Alias:
gastric inhibitory peptide receptor; gastric inhibitory polypeptide receptor; GIP receptor; Gippr; Gipr; GIP-R; Glucose-dependent insulinotropic polypeptide receptor; Gm1081; Gm160; PGQTL2; RATGIPPR
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
2696
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid